Genetics and Product Formation in Streptomyces

Download Genetics and Product Formation in Streptomyces PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468459228
Total Pages : 318 pages
Book Rating : 4.4/5 (684 download)

DOWNLOAD NOW!


Book Synopsis Genetics and Product Formation in Streptomyces by : Simon Baumberg

Download or read book Genetics and Product Formation in Streptomyces written by Simon Baumberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Streptomycetes are industrially widely used microorganisms due to their ability to produce numerous different chemical compounds. These show very varied effects upon other living systems, and result from profound and subtle biochemical and morphological differentiation during the streptomycete life cycle. It is therefore not surprising that research on the genetics of antibiotic biosynthesis and differentiation in this group is currently progressing rapidly in many countries. Intimately connected with the production of antibiotics is resistance to them; analysis of this is giving further information about the origin and evolution of this class of genes and their hypothesized spread among other microorganisms. Another interesting feature of the Streptomyces group is their mycelial growth. Also, their ecologically important utilization of high molecular weight compounds requires enzymes to be transported outside the cell to hydrolyze non-diffusible substrates. Finally, we have as yet limited understanding of the various mechanisms of genome rearrangement observed in some of these species; deletions and/or amplifications of enormous amounts of DNA can occur without seriously affecting the viability of the organism under laboratory conditions. The present volume, which includes contributions addressing the above subjects and others, originates from a meeting on "Genetics and Product Formation in Streptomyces" sponsored by the Federation of European Microbiological Societies in Erfurt on May 1-6 1990. Compared to previous ones of this kind held in 1979, 1983 and 1987 in Weimar, one can point to impressive progress in the study and applications of Streptomyces genetics.

Canadian Journal of Microbiology

Download Canadian Journal of Microbiology PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.3/5 ( download)

DOWNLOAD NOW!


Book Synopsis Canadian Journal of Microbiology by :

Download or read book Canadian Journal of Microbiology written by and published by . This book was released on 1996 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Enzyme Technologies for Pharmaceutical and Biotechnological Applications

Download Enzyme Technologies for Pharmaceutical and Biotechnological Applications PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9781420002348
Total Pages : 642 pages
Book Rating : 4.0/5 (23 download)

DOWNLOAD NOW!


Book Synopsis Enzyme Technologies for Pharmaceutical and Biotechnological Applications by : Herbert A Kirst

Download or read book Enzyme Technologies for Pharmaceutical and Biotechnological Applications written by Herbert A Kirst and published by CRC Press. This book was released on 2001-06-05 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of enzyme function in human and animal health, this book covers basic principles and applications in antibiotic biosynthesis, biocatalysis, and screening and assay optimization, as well as new and emerging technologies in the biotechnological and pharmaceutical industries. It offers real-world examples of timely laboratory, pharmaceutical and manufacturing processes, including large-scale applications of enzyme manipulations.

Metabolic Engineering of Cephalosporin Biosynthesis in Streptomyces Clavuligerusc︢

Download Metabolic Engineering of Cephalosporin Biosynthesis in Streptomyces Clavuligerusc︢ PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.:/5 (319 download)

DOWNLOAD NOW!


Book Synopsis Metabolic Engineering of Cephalosporin Biosynthesis in Streptomyces Clavuligerusc︢ by : Li-Hong Malmberg

Download or read book Metabolic Engineering of Cephalosporin Biosynthesis in Streptomyces Clavuligerusc︢ written by Li-Hong Malmberg and published by . This book was released on 1995 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides

Download Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0080923356
Total Pages : 703 pages
Book Rating : 4.0/5 (89 download)

DOWNLOAD NOW!


Book Synopsis Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides by :

Download or read book Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides written by and published by Academic Press. This book was released on 2009-04-10 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field In depth coverage of ribosomally-synthesised and Non-ribosomally-synthesised peptides Provides an extremely useful reference for the experienced research scientist

Synthesis of β-Lactam Antibiotics

Download Synthesis of β-Lactam Antibiotics PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401008507
Total Pages : 328 pages
Book Rating : 4.4/5 (1 download)

DOWNLOAD NOW!


Book Synopsis Synthesis of β-Lactam Antibiotics by : Alle Bruggink

Download or read book Synthesis of β-Lactam Antibiotics written by Alle Bruggink and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.

Enzymes Finger Printing

Download Enzymes Finger Printing PDF Online Free

Author :
Publisher : Discovery Publishing House
ISBN 13 : 9788183564090
Total Pages : 334 pages
Book Rating : 4.5/5 (64 download)

DOWNLOAD NOW!


Book Synopsis Enzymes Finger Printing by : Arvind N. Shukla

Download or read book Enzymes Finger Printing written by Arvind N. Shukla and published by Discovery Publishing House. This book was released on 2009 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics and Biochemistry of Antibiotic Production

Download Genetics and Biochemistry of Antibiotic Production PDF Online Free

Author :
Publisher : Butterworth-Heinemann
ISBN 13 : 1483295079
Total Pages : 704 pages
Book Rating : 4.4/5 (832 download)

DOWNLOAD NOW!


Book Synopsis Genetics and Biochemistry of Antibiotic Production by : Colin Stuttard

Download or read book Genetics and Biochemistry of Antibiotic Production written by Colin Stuttard and published by Butterworth-Heinemann. This book was released on 2014-06-28 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Emphasizes the molecular genetics of antibiotic production * Provides the latest information on the organization of genes encoding the biosynthetic pathway * Explores the mechanisms governing their expression and regulation * Examines the role of resistance genes in protecting organisms from their own lethal products Genetics and Biochemistry of Antibiotic Production brings together the most up-to-date information on the genetic and biochemical mechanisms involved in antibiotic production. A collection of internationally recognized authors provide the latest information on the organization, function and regulation of genes responsible for antibiotic synthesis in a range of bacteria. This unique book groups antibiotics according to their biosynthetic affiliation, providing a background into evolutionary relationships while raising intriguing questions about the raison d'etre of antibiotics in nature.

Analysis of Temporal and Spatial Control of Cephamycin C Biosynthesis in Streptomyces Clavuligerus

Download Analysis of Temporal and Spatial Control of Cephamycin C Biosynthesis in Streptomyces Clavuligerus PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 354 pages
Book Rating : 4.:/5 (319 download)

DOWNLOAD NOW!


Book Synopsis Analysis of Temporal and Spatial Control of Cephamycin C Biosynthesis in Streptomyces Clavuligerus by : Anurag Khetan

Download or read book Analysis of Temporal and Spatial Control of Cephamycin C Biosynthesis in Streptomyces Clavuligerus written by Anurag Khetan and published by . This book was released on 1998 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Class 1 Oxidoreductases XII

Download Class 1 Oxidoreductases XII PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540304398
Total Pages : 691 pages
Book Rating : 4.5/5 (43 download)

DOWNLOAD NOW!


Book Synopsis Class 1 Oxidoreductases XII by : Antje Chang

Download or read book Class 1 Oxidoreductases XII written by Antje Chang and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

Bioreaction Engineering Principles

Download Bioreaction Engineering Principles PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 1461507677
Total Pages : 537 pages
Book Rating : 4.4/5 (615 download)

DOWNLOAD NOW!


Book Synopsis Bioreaction Engineering Principles by : Jens Nielsen

Download or read book Bioreaction Engineering Principles written by Jens Nielsen and published by Springer. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.

Microbiology

Download Microbiology PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 784 pages
Book Rating : 4.3/5 (555 download)

DOWNLOAD NOW!


Book Synopsis Microbiology by :

Download or read book Microbiology written by and published by . This book was released on 1996-07 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Engineering

Download Genetic Engineering PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461306418
Total Pages : 346 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!


Book Synopsis Genetic Engineering by : Jane K. Setlow

Download or read book Genetic Engineering written by Jane K. Setlow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixteen contributions cover such topics as the polymerase chain reaction; regulation of alternative splicing; human retinoblastoma susceptibility gene; control of translation initiation in mammalian cells; the utility of streptomycetes as hosts for gene cloning; folding of eukaryotic proteins produc

FEMS Microbiology Letters

Download FEMS Microbiology Letters PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 976 pages
Book Rating : 4.X/5 (6 download)

DOWNLOAD NOW!


Book Synopsis FEMS Microbiology Letters by :

Download or read book FEMS Microbiology Letters written by and published by . This book was released on 1999 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international journal providing for the rapid publication of short reports on microbiological research.

Advances in Enzymology and Related Areas of Molecular Biology, Volume 72, Part A

Download Advances in Enzymology and Related Areas of Molecular Biology, Volume 72, Part A PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470123974
Total Pages : 466 pages
Book Rating : 4.4/5 (71 download)

DOWNLOAD NOW!


Book Synopsis Advances in Enzymology and Related Areas of Molecular Biology, Volume 72, Part A by : Daniel L. Purich

Download or read book Advances in Enzymology and Related Areas of Molecular Biology, Volume 72, Part A written by Daniel L. Purich and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is Part A in a subseries entitled "Amino Acid Metabolism". Topics in Part A should be of immediate interest to those who are broadly concerned with amino acid assimilation and metabolism. Investigators interested in enzyme mechanism and regulation will also find this volume especially valuable.

Enzymology Primer for Recombinant DNA Technology

Download Enzymology Primer for Recombinant DNA Technology PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 008053113X
Total Pages : 727 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!


Book Synopsis Enzymology Primer for Recombinant DNA Technology by : Hyone-Myong Eun

Download or read book Enzymology Primer for Recombinant DNA Technology written by Hyone-Myong Eun and published by Elsevier. This book was released on 1996-06-03 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes are indispensable tools in recombinant DNA technology and genetic engineering. This book not only provides information for enzymologists, but does so in a manner that will also aid nonenymologists in making proper use of these biocatalysts in their research. The Enzymology Primer for Recombinant DNA Technology includes information not usually found in the brief descriptions given in most books on recombinant DNA methodology and gene cloning. Provides essential basics as well as up-to-date information on enzymes most commonly used in recombinant DNA technology Presents information in an easily accessible format to serve as a quick reference source Leads to a better understanding of the role of biocatalysts in recombinant DNA techniques

Evolution of Metabolic Pathways

Download Evolution of Metabolic Pathways PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080531326
Total Pages : 481 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!


Book Synopsis Evolution of Metabolic Pathways by : R. Ibrahim

Download or read book Evolution of Metabolic Pathways written by R. Ibrahim and published by Elsevier. This book was released on 2000-09-15 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen major advances in the cloning of genes encoding enzymes of plant secondary metabolism. This has been further enhanced by the recent project on the sequencing of the Arabidopsis genome. These developments provide the molecular genetic basis to address the question of the Evolution of Metabolic Pathways. This volume provides in-depth reviews of our current knowledge on the evolutionary origin of plant secondary metabolites and the enzymes involved in their biosynthesis. The chapters cover five major topics: 1. Role of secondary metabolites in evolution; 2. Evolutionary origins of polyketides and terpenes; 3. Roles of oxidative reactions in the evolution of secondary metabolism; 4. Evolutionary origin of substitution reactions: acylation, glycosylation and methylation; and 5. Biochemistry and molecular biology of brassinosteroids.