Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine

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Publisher : Elsevier
ISBN 13 : 0323972624
Total Pages : 556 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine by : J. Miguel Oliveira

Download or read book Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine written by J. Miguel Oliveira and published by Elsevier. This book was released on 2023-11-28 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related injuries that can affect muscles, bones and joints and lead to severe complications of the neuromuscular system, it is imperative to develop new treatment strategies to delay or repair associated diseases and to promote optimal long-term health. Presents the fundamentals of the complex interplay of cells with biomaterials in musculoskeletal tissue engineering Includes coverage of stem cells and cell-based therapies, in vitro and in vivo models, nanotechnology, bioprinting, computational modeling, regulatory and clinical translation, and much more Written by global leaders in the field

Musculoskeletal Tissue Engineering

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Author :
Publisher : Elsevier
ISBN 13 : 0128242108
Total Pages : 385 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Musculoskeletal Tissue Engineering by : Yupeng Chen

Download or read book Musculoskeletal Tissue Engineering written by Yupeng Chen and published by Elsevier. This book was released on 2021-11-04 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Musculoskeletal Tissue Engineering introduces the fundamental concepts and translational applications of musculoskeletal tissue engineering, in combination with emerging technologies and materials. Sections discuss Tissues and Technologies, covering a range of musculoskeletal tissues, including bone, cartilage, ligament and more. Each chapter in this section details core tissue engineering principles specific to each tissue type. Next, a Technologies section looks at the range of biomaterials used in musculoskeletal tissue engineering, focusing on biocompatibility of materials and interactions at the material-tissue interface. Other chapters cover nanotechnology, 3D printing, gene therapy, tissue chips, and more. This book offers an advanced reference text for researchers in biomedical engineering, materials science and regenerative medicine. Details various materials and cutting-edge technologies for musculoskeletal tissue engineering Covers a range of musculoskeletal tissues, including bone, cartilage, ligament, tendon, meniscus, and more Provides a balance between basic concepts and translational applications for a broad audience

Regenerative Engineering of Musculoskeletal Tissues and Interfaces

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Author :
Publisher : Woodhead Publishing
ISBN 13 : 1782423141
Total Pages : 462 pages
Book Rating : 4.7/5 (824 download)

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Book Synopsis Regenerative Engineering of Musculoskeletal Tissues and Interfaces by : Syam Nukavarapu

Download or read book Regenerative Engineering of Musculoskeletal Tissues and Interfaces written by Syam Nukavarapu and published by Woodhead Publishing. This book was released on 2015-04-24 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine

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Author :
Publisher : Academic Press
ISBN 13 : 0128033991
Total Pages : 252 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine by : Justin Brown

Download or read book Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine written by Justin Brown and published by Academic Press. This book was released on 2016-11-03 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine Focuses on how materials of structures can be designed to be resistant while promoting viable grafts Contains major tissue types that are covered with a strategy for each material and structure

Biomaterials and Stem Cells in Regenerative Medicine

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Publisher : CRC Press
ISBN 13 : 1439879257
Total Pages : 567 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biomaterials and Stem Cells in Regenerative Medicine by : Murugan Ramalingam

Download or read book Biomaterials and Stem Cells in Regenerative Medicine written by Murugan Ramalingam and published by CRC Press. This book was released on 2012-07-03 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include: Polymeric systems for stem cell delivery The potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissues The optimization of the interaction between stem cells and biomaterial substrates The source and nature of stem cells for tissue engineering applications The clinical translation of stem cell–based tissue engineering for regenerative medicine From fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

Biomaterials for Musculoskeletal Regeneration

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Author :
Publisher : Springer
ISBN 13 : 9811030596
Total Pages : 420 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Biomaterials for Musculoskeletal Regeneration by : Bikramjit Basu

Download or read book Biomaterials for Musculoskeletal Regeneration written by Bikramjit Basu and published by Springer. This book was released on 2016-11-01 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the basics of the biomaterials science its applications to bone tissue engineering. The introductory section describes the most necessary concepts and techniques related to the cell and molecular biology with a particular focus on evaluating the biocompatibility property. The layout of this book facilitates easier understanding of the area of bone tissue engineering. The book integrates the Materials Science and Biological Science. It covers processing and basic material properties of various biocompatible metals and ceramics-based materials, in vitro and in vivo biocompatibility and toxicity assessment in the context of bone tissue engineering, and processing and properties of metal-, ceramic- and polymer-based biocomposites, including the fabrication of porous scaffold materials. The book can be used as a textbook for senior undergraduate and graduate coursework. It will also be a useful reference for researchers and professionals working in the area.

A Tissue Regeneration Approach to Bone and Cartilage Repair

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Author :
Publisher : Springer
ISBN 13 : 9783319379715
Total Pages : 0 pages
Book Rating : 4.3/5 (797 download)

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Book Synopsis A Tissue Regeneration Approach to Bone and Cartilage Repair by : Hala Zreiqat

Download or read book A Tissue Regeneration Approach to Bone and Cartilage Repair written by Hala Zreiqat and published by Springer. This book was released on 2016-09-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

Engineering Stem Cells for Tissue Regeneration

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Author :
Publisher :
ISBN 13 : 9789813147751
Total Pages : 542 pages
Book Rating : 4.1/5 (477 download)

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Book Synopsis Engineering Stem Cells for Tissue Regeneration by : Ngan Huang

Download or read book Engineering Stem Cells for Tissue Regeneration written by Ngan Huang and published by . This book was released on 2018 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bone Tissue Engineering

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Publisher : CRC Press
ISBN 13 : 1135501912
Total Pages : 500 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger

Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Muscle Regeneration

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Author :
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 582 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Muscle Regeneration by : Alexander Mauro

Download or read book Muscle Regeneration written by Alexander Mauro and published by Raven Press (ID). This book was released on 1979 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Articular Cartilage Tissue Engineering

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1598298755
Total Pages : 183 pages
Book Rating : 4.5/5 (982 download)

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Book Synopsis Articular Cartilage Tissue Engineering by : Kyriacos A. Athanasiou

Download or read book Articular Cartilage Tissue Engineering written by Kyriacos A. Athanasiou and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

Tissue Repair, Contraction and the Myofibroblast

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Publisher : Springer Science & Business Media
ISBN 13 : 0387336508
Total Pages : 154 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Tissue Repair, Contraction and the Myofibroblast by : Christine Chaponnier

Download or read book Tissue Repair, Contraction and the Myofibroblast written by Christine Chaponnier and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Repair, Contraction and the Myofibroblast summarizes the latest findings concerning the biology of the myofibroblast, a cell involved in the evolution and contraction of granulation tissue and of fibrotic changes. Coverage shows that the myofibroblast is responsible for the development of hypertrophic scars, pulmonary and renal fibrosis and bronchial asthma. Reviews the cell biology and pathology of the myofibroblast as well as mechanisms of fibrosis evolution in many organs and tissues.

Functional Tissue Engineering

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Publisher : Springer Science & Business Media
ISBN 13 : 0387955534
Total Pages : 434 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Functional Tissue Engineering by : Farshid Guilak

Download or read book Functional Tissue Engineering written by Farshid Guilak and published by Springer Science & Business Media. This book was released on 2003-07-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: -Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology

Neural Tissue Biomechanics

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Publisher : Springer Science & Business Media
ISBN 13 : 9783642138904
Total Pages : 288 pages
Book Rating : 4.1/5 (389 download)

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Book Synopsis Neural Tissue Biomechanics by : Lynne E. Bilston

Download or read book Neural Tissue Biomechanics written by Lynne E. Bilston and published by Springer Science & Business Media. This book was released on 2011-07-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Damage to the central nervous system resulting from pathological mechanical loading can occur as a result of trauma or disease. Such injuries lead to significant disability and mortality. The peripheral nervous system, while also subject to injury from trauma and disease, also transduces physiological loading to give rise to sensation, and mechanotransduction is also thought to play a role in neural development and growth. This book gives a complete and quantitative description of the fundamental mechanical properties of neural tissues, and their responses to both physiological and pathological loading. This book reviews the methods used to characterize the nonlinear viscoelastic properties of central and peripheral neural tissues, and the mathematical and sophisticated computational models used to describe this behaviour. Mechanisms and models of neural injury from both trauma and disease are reviewed from the molecular to macroscopic scale. The book provides a comprehensive picture of the mechanical and biological response of neural tissues to the full spectrum of mechanical loading to which they are exposed. This book provides a comprehensive reference for professionals involved in pre prevention of injury to the nervous system, whether this arises from trauma or disease.

3D Bioprinting for Reconstructive Surgery

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Publisher : Woodhead Publishing
ISBN 13 : 0081012160
Total Pages : 450 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis 3D Bioprinting for Reconstructive Surgery by : Daniel Thomas

Download or read book 3D Bioprinting for Reconstructive Surgery written by Daniel Thomas and published by Woodhead Publishing. This book was released on 2017-11-14 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. Discusses new possibilities in tissue engineering with 3D printing Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues Reviews emerging technologies in addition to commercial techniques

Decellularized Materials

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Publisher : Springer Nature
ISBN 13 : 9813369620
Total Pages : 517 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Decellularized Materials by : Xiaoming Li

Download or read book Decellularized Materials written by Xiaoming Li and published by Springer Nature. This book was released on 2021-04-28 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.

Stem Cell Engineering

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Publisher : Springer Science & Business Media
ISBN 13 : 3642118658
Total Pages : 547 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Stem Cell Engineering by : Gerhard M. Artmann

Download or read book Stem Cell Engineering written by Gerhard M. Artmann and published by Springer Science & Business Media. This book was released on 2010-10-29 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.