Monte Carlo in Heavy Charged Particle Therapy

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Author :
Publisher : CRC Press
ISBN 13 : 1000987655
Total Pages : 528 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Monte Carlo in Heavy Charged Particle Therapy by : Pablo Cirrone

Download or read book Monte Carlo in Heavy Charged Particle Therapy written by Pablo Cirrone and published by CRC Press. This book was released on 2023-11-08 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the current difficulties and unsolved problems in the field of particle therapy and, after analysing them, discusses how (and if) innovative Monte Carlo approaches can be used to solve them. Each book chapter is dedicated to a different sub-discipline, including multi-ion treatments, flash-radiotherapy, laser-accelerated beams, nanoparticles effects, binary reactions to enhance radiobiology, and space-related issues. This is the first book able to provide a comprehensive insight into this exciting field and the growing use of Monte Carlo in medical physics. It will be of interest to graduate students in medicine and medical physics, in addition to researchers and clinical staff. Key Features: Explores the exciting and interdisciplinary topic of Monte Carlo in particle therapy and medicine. Addresses common challenges in the field. Edited by an authority on the subject, with chapter contributions from specialists. Pablo Cirrone is a medical physicist and researcher at the Laboratori Nazionali del Sud of INFN, Italy, where he supports and coordinates various experimental groups. Dr. Cirrone is an expert in the use of proton and ion in radiation treatment and of absolute and relative dosimetry in electron, photon and ion beam. He is an expert in the development and test of detectors for medical applications, of the production and use of laser-driven beams for medical and multidisciplinary applications and recipient of the Michael Gotein Award. He is active on many scientific committees and organizes national and international conferences. Giada Petringa is a researcher at the Laboratori Nazionali del Sud of INFN, Italy. Dr. Petringa has a professional experience in the field of Monte Carlo simulations for medical applications, dosimetry, microdosimetry, and diagnostics with conventional and laser-driven proton beams. In 2019 she had a MSCA-IF-2019 (Marie Sklodowska-Curie Actions-Individual Fellowship) grant funded by the European Community in the framework of the H2020 program. She is a member of the Editorial Board of the international journal Physica Medica - European Journal of Medical. She organized more than fifteen international Geant4 Schools. She is an official member of the Geant4 code Collaboration at CERN since 2019. She is a code developer, and she collaborates to maintain two of the official examples of the code.

Proton Therapy Physics

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Publisher : CRC Press
ISBN 13 : 1439836450
Total Pages : 691 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Proton Therapy Physics by : Harald Paganetti

Download or read book Proton Therapy Physics written by Harald Paganetti and published by CRC Press. This book was released on 2016-04-19 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Calculation of Radiation Therapy Dose Using All Particle Monte Carlo Transport

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (873 download)

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Book Synopsis Calculation of Radiation Therapy Dose Using All Particle Monte Carlo Transport by :

Download or read book Calculation of Radiation Therapy Dose Using All Particle Monte Carlo Transport written by and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The actual radiation dose absorbed in the body is calculated using three-dimensional Monte Carlo transport. Neutrons, protons, deuterons, tritons, helium-3, alpha particles, photons, electrons, and positrons are transported in a completely coupled manner, using this Monte Carlo All-Particle Method (MCAPM). The major elements of the invention include: computer hardware, user description of the patient, description of the radiation source, physical databases, Monte Carlo transport, and output of dose distributions. This facilitated the estimation of dose distributions on a Cartesian grid for neutrons, photons, electrons, positrons, and heavy charged-particles incident on any biological target, with resolutions ranging from microns to centimeters. Calculations can be extended to estimate dose distributions on general-geometry (non-Cartesian) grids for biological and/or non-biological media.

Monte Carlo Methods for Radiation Transport

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Author :
Publisher : Springer
ISBN 13 : 3319441418
Total Pages : 292 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Monte Carlo Methods for Radiation Transport by : Oleg N. Vassiliev

Download or read book Monte Carlo Methods for Radiation Transport written by Oleg N. Vassiliev and published by Springer. This book was released on 2016-10-17 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a guide to the use of Monte Carlo techniques in radiation transport. This topic is of great interest for medical physicists. Praised as a "gold standard" for accurate radiotherapy dose calculations, Monte Carlo has stimulated a high level of research activity that has produced thousands of papers within the past few years. The book is designed primarily to address the needs of an academically inclined medical physicist who wishes to learn the technique, as well as experienced users of standard Monte Carlo codes who wish to gain insight into the underlying mathematics of Monte Carlo algorithms. The book focuses on the fundamentals—giving full attention to and explaining the very basic concepts. It also includes advanced topics and covers recent advances such as transport of charged particles in magnetic fields and the grid-based solvers of the Boltzmann equation.

PEREGRINE

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Publisher :
ISBN 13 :
Total Pages : 11 pages
Book Rating : 4.:/5 (683 download)

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Book Synopsis PEREGRINE by :

Download or read book PEREGRINE written by and published by . This book was released on 1994 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of radiation therapy is to deliver a lethal dose to the tumor while minimizing the dose to normal tissues. To carry out this task, it is critical to calculate correctly the distribution of dose delivered. Monte Carlo transport methods have the potential to provide more accurate prediction of dose distributions than currently-used methods. PEREGRINE is a new Monte Carlo transport code developed at Lawrence Livermore National Laboratory for the specific purpose of modeling the effects of radiation therapy. PEREGRINE transports neutrons, photons, electrons, positrons, and heavy charged-particles, including protons, deuterons, tritons, helium-3, and alpha particles. This paper describes the PEREGRINE transport code and some preliminary results for clinically relevant materials and radiation sources.

Charged Particles in Oncology

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Publisher : Frontiers Media SA
ISBN 13 : 288945391X
Total Pages : 650 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Charged Particles in Oncology by : Marco Durante

Download or read book Charged Particles in Oncology written by Marco Durante and published by Frontiers Media SA. This book was released on 2018-01-31 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.

State-of-the-art Reviews on Energetic Ion-atom and Ion-molecule Collisions

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Publisher : World Scientific Publishing Company
ISBN 13 : 9789811211607
Total Pages : 0 pages
Book Rating : 4.2/5 (116 download)

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Book Synopsis State-of-the-art Reviews on Energetic Ion-atom and Ion-molecule Collisions by : Dževad Belkić

Download or read book State-of-the-art Reviews on Energetic Ion-atom and Ion-molecule Collisions written by Dževad Belkić and published by World Scientific Publishing Company. This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book is based upon a part of the invited and contributing talks at the 25th International Symposium on Ion-Atom Collisions, ISIAC (biennial), held on July 23-25, 2017 in Palm Cove, Queensland, Australia. To aid the general reader, all the authors tried to present their chapters in the context of the development of the addressed particular themes and the underlying major ideas and intricacies. Some chapters contain new results that have not been previously published elsewhere. Whenever possible, the authors made their attempts to connect the basic research in atomic and molecular collision physics with some important applications in other branches of physics as well as across the physics borders. It is hoped that the material presented in this book will be interesting and useful to the beginners and specialists alike. The contents and expositions are deemed to be helpful to the beginners in assessing the potential overlap of some of the presented material with their own research themes and this might provide motivations for possible further upgrades. Likewise, specialists could take advantage of these reviews to see where the addressed themes were and where they are going, in order to acknowledge the fruits of the efforts made thus far and actively contribute to tailoring the directions of future research. Overall, this book is truly interdisciplinary. It judiciously combines experiments and theories within particle collision physics on atomic and molecular levels. It presents state-of-the-art fundamental research in this field. It addresses the possibilities for significant and versatile applications outside standard atomic and molecular collision physics ranging from astrophysics, surface as well as cluster physics/chemistry, hadron therapy in medicine and to the chemical industry. It is then, as Volume 2, fully in the spirit of the "Aims and Scope" of this book series by reference to its "Mission Statement"."-- Back cover.

Proton and Carbon Ion Therapy

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Author :
Publisher : CRC Press
ISBN 13 : 1439816085
Total Pages : 254 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Proton and Carbon Ion Therapy by : C-M Charlie Ma

Download or read book Proton and Carbon Ion Therapy written by C-M Charlie Ma and published by CRC Press. This book was released on 2012-10-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and trea

Particle Radiotherapy

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Publisher : Springer
ISBN 13 : 8132226224
Total Pages : 203 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Particle Radiotherapy by : Arabinda Kumar Rath

Download or read book Particle Radiotherapy written by Arabinda Kumar Rath and published by Springer. This book was released on 2016-03-10 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The results of decades of research and development are providing compelling evidence about the efficacy of radiation therapy with proton and carbon ion beams to achieve superior complication free tumor control leading to a world-wide rapid growth in their clinical use. This book contains comprehensive reviews of the state of the art of the technology and physics of heavy charge particle therapy by the experts from the leading cancer centers of world that will be valuable as a practical guide for radiation therapy professionals interested in these modalities.

New Technologies in Radiation Oncology

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Publisher : Springer Science & Business Media
ISBN 13 : 3540299998
Total Pages : 453 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis New Technologies in Radiation Oncology by : Wolfgang C. Schlegel

Download or read book New Technologies in Radiation Oncology written by Wolfgang C. Schlegel and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Summarizes the state of the art in the most relevant areas of medical physics and engineering applied to radiation oncology - Covers all relevant areas of the subject in detail, including 3D imaging and image processing, 3D treatment planning, modern treatment techniques, patient positioning, and aspects of verification and quality assurance - Conveys information in a readily understandable way that will appeal to professionals and students with a medical background as well as to newcomers to radiation oncology from the field of physics

Monte Carlo Simulations Using MCNPX of Proton and Anti-proton Beam Profiles for Radiation Therapy

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Publisher :
ISBN 13 :
Total Pages : 186 pages
Book Rating : 4.:/5 (642 download)

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Book Synopsis Monte Carlo Simulations Using MCNPX of Proton and Anti-proton Beam Profiles for Radiation Therapy by : Stephen Michael Handley

Download or read book Monte Carlo Simulations Using MCNPX of Proton and Anti-proton Beam Profiles for Radiation Therapy written by Stephen Michael Handley and published by . This book was released on 2010 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Monte Carlo Techniques in Radiation Therapy

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Publisher : CRC Press
ISBN 13 : 1000455556
Total Pages : 291 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Monte Carlo Techniques in Radiation Therapy by : Frank Verhaegen

Download or read book Monte Carlo Techniques in Radiation Therapy written by Frank Verhaegen and published by CRC Press. This book was released on 2021-11-29 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: About ten years after the first edition comes this second edition of Monte Carlo Techniques in Radiation Therapy: Introduction, Source Modelling, and Patient Dose Calculations, thoroughly updated and extended with the latest topics, edited by Frank Verhaegen and Joao Seco. This book aims to provide a brief introduction to the history and basics of Monte Carlo simulation, but again has a strong focus on applications in radiotherapy. Since the first edition, Monte Carlo simulation has found many new applications, which are included in detail. The applications sections in this book cover the following: Modelling transport of photons, electrons, protons, and ions Modelling radiation sources for external beam radiotherapy Modelling radiation sources for brachytherapy Design of radiation sources Modelling dynamic beam delivery Patient dose calculations in external beam radiotherapy Patient dose calculations in brachytherapy Use of artificial intelligence in Monte Carlo simulations This book is intended for both students and professionals, both novice and experienced, in medical radiotherapy physics. It combines overviews of development, methods, and references to facilitate Monte Carlo studies.

Monte Carlo Techniques in Radiation Therapy

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Publisher : CRC Press
ISBN 13 : 1466507926
Total Pages : 344 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Monte Carlo Techniques in Radiation Therapy by : Joao Seco

Download or read book Monte Carlo Techniques in Radiation Therapy written by Joao Seco and published by CRC Press. This book was released on 2013-03-25 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern cancer treatment relies on Monte Carlo simulations to help radiotherapists and clinical physicists better understand and compute radiation dose from imaging devices as well as exploit four-dimensional imaging data. With Monte Carlo-based treatment planning tools now available from commercial vendors, a complete transition to Monte Carlo-based dose calculation methods in radiotherapy could likely take place in the next decade. Monte Carlo Techniques in Radiation Therapy explores the use of Monte Carlo methods for modeling various features of internal and external radiation sources, including light ion beams. The book—the first of its kind—addresses applications of the Monte Carlo particle transport simulation technique in radiation therapy, mainly focusing on external beam radiotherapy and brachytherapy. It presents the mathematical and technical aspects of the methods in particle transport simulations. The book also discusses the modeling of medical linacs and other irradiation devices; issues specific to electron, photon, and proton ion beams and brachytherapy; and the optimization of treatment planning, radiation dosimetry, and quality assurance. Useful to clinical physicists, graduate students, and researchers, this book provides a detailed, state-of-the-art guide to the fundamentals, application, and customization of Monte Carlo techniques in radiotherapy. Through real-world examples, it illustrates the use of Monte Carlo modeling and simulations in dose calculation, beam delivery, kilovoltage and megavoltage imaging, proton radiography, device design, and much more.

Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility

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Publisher : Springer
ISBN 13 : 3658131683
Total Pages : 99 pages
Book Rating : 4.6/5 (581 download)

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Book Synopsis Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility by : Matthias Würl

Download or read book Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility written by Matthias Würl and published by Springer. This book was released on 2016-05-30 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Matthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emitter production cross-sections. In the first part, the field size dependence of the dose output is described for scanned proton beams. Both the Monte Carlo and an analytical computational beam model were able to accurately predict target dose, while the latter tends to overestimate dose in normal tissue. In the second part, the author presents PET measurements of different phantom materials, which were activated by the proton beam. The results indicate that for an irradiation with a high number of protons for the sake of good statistics, dead time losses of the PET scanner may become important and lead to an underestimation of positron-emitter production yields.

Proton Therapy Physics, Second Edition

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Publisher : CRC Press
ISBN 13 : 1351855751
Total Pages : 772 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis Proton Therapy Physics, Second Edition by : Harald Paganetti

Download or read book Proton Therapy Physics, Second Edition written by Harald Paganetti and published by CRC Press. This book was released on 2018-11-19 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics. Features: Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering Discusses clinical aspects, such as treatment planning and quality assurance Offers insight on the past, present, and future of proton therapy from a physics perspective

Particle Physics Reference Library

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Publisher : Springer Nature
ISBN 13 : 3030353184
Total Pages : 1083 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Particle Physics Reference Library by : Christian W. Fabjan

Download or read book Particle Physics Reference Library written by Christian W. Fabjan and published by Springer Nature. This book was released on 2020 with total page 1083 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second open access volume of the handbook series deals with detectors, large experimental facilities and data handling, both for accelerator and non-accelerator based experiments. It also covers applications in medicine and life sciences. A joint CERN-Springer initiative, the "Particle Physics Reference Library" provides revised and updated contributions based on previously published material in the well-known Landolt-Boernstein series on particle physics, accelerators and detectors (volumes 21A, B1,B2,C), which took stock of the field approximately one decade ago. Central to this new initiative is publication under full open access

Principles and Practice of Proton Bean Therapy, AAPM Monograph

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Publisher :
ISBN 13 : 9781936366439
Total Pages : 828 pages
Book Rating : 4.3/5 (664 download)

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Book Synopsis Principles and Practice of Proton Bean Therapy, AAPM Monograph by : Indra J. Das

Download or read book Principles and Practice of Proton Bean Therapy, AAPM Monograph written by Indra J. Das and published by . This book was released on 2015-06-22 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: