Molecular Regulation Of The Mhc Class Ii Associated Invariant Chain Gene Ii Expression

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B Cell Receptor Signaling

Author : Tomohiro Kurosaki
Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 233 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis B Cell Receptor Signaling by : Tomohiro Kurosaki

Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Medical Biochemistry

Author : Chung Eun Ha
Publisher : Academic Press
ISBN 13 : 0080916880
Total Pages : 600 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Essentials of Medical Biochemistry by : Chung Eun Ha

Download or read book Essentials of Medical Biochemistry written by Chung Eun Ha and published by Academic Press. This book was released on 2011-01-28 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert biochemist N.V. Bhagavan's new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor. - Clinical focus emphasizing relevant physiologic and pathophysiologic biochemical concepts - Interactive multiple-choice questions to prep for USMLE exams - Clinical case studies for understanding basic science, diagnosis, and treatment of human diseases - Instructional overview figures, flowcharts, and tables to enhance understanding

Naturally Processed Peptides

Author : Alessandro Sette
Publisher : S Karger Ag
ISBN 13 : 9783805557559
Total Pages : 0 pages
Book Rating : 4.5/5 (575 download)

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Book Synopsis Naturally Processed Peptides by : Alessandro Sette

Download or read book Naturally Processed Peptides written by Alessandro Sette and published by S Karger Ag. This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Regulation of the MHC Class II-associated Invariant Chain Gene (Ii) Expression

Author : Li Zhu
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Molecular Regulation of the MHC Class II-associated Invariant Chain Gene (Ii) Expression by : Li Zhu

Download or read book Molecular Regulation of the MHC Class II-associated Invariant Chain Gene (Ii) Expression written by Li Zhu and published by . This book was released on 1990 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Herpesviruses

Author : Ann Arvin
Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Human Herpesviruses by : Ann Arvin

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Gene Vaccines

Author : Josef Thalhamer
Publisher : Springer Science & Business Media
ISBN 13 : 3709104394
Total Pages : 332 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Gene Vaccines by : Josef Thalhamer

Download or read book Gene Vaccines written by Josef Thalhamer and published by Springer Science & Business Media. This book was released on 2011-08-31 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.

Immunology and Developmental Biology of the Chicken

Author : Olli Vainio
Publisher : Springer Science & Business Media
ISBN 13 : 3642800572
Total Pages : 281 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Immunology and Developmental Biology of the Chicken by : Olli Vainio

Download or read book Immunology and Developmental Biology of the Chicken written by Olli Vainio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Books on both chicken immunology and developmental biology are rare. This one, however, summarizes all aspects of both areas and therefore represents a valuable compendium for experienced researchers as well as for all newcomers to the field. Following a lengthy discussion of the origin of hemopoietic cells, regulatory elements for the differentiation of these cells and B and T cell lymphopoiesis, the book goes on to describe the generation of transgenic chickens as well as an additional basic feature in embryogenesis: the positioning of organ anlage, e.g. the limb bud. To round off, a valuable compilation of monoclonal antibodies further enhances the practical usefulness of this important book.

HLA in Health and Disease

Author : Robert Lechler
Publisher : Academic Press
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HLA in Health and Disease by : Robert Lechler

Download or read book HLA in Health and Disease written by Robert Lechler and published by Academic Press. This book was released on 2000-05-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and definitive work succeeds and expands on the highly successful HLA and Disease published in 1994. This new edition has been updated, redesigned and reorganised into three sections making it an invaluable reference. The introductory section summarises current knowledge on the structure, function, genetics and evolution of the HLA system. It clarifies its complex and ever changing nomenclature and discusses the mechanisms underlying disease associations with HLA alleles. The second section deals with the importance of HLA in the context of different clinical specialities. Individual chapters describe the association between HLA polymorphism and each disease. The final section features chapters on current laboratory practice in histocompatibility and tissue typing. HLA in Health and Disease is essential reading for basic and clinical researchers working in immunology and immunogenetics, transplantation medicine and autoimmunity. It will also be of interest to anyone in the fields of rheumatology, diabetology, nephrology, allergy, dermatology, neurology, endocrinology, cancer biology, respiratory medicine, haematology, molecular biology and biochemistry. Key Features Structure, function and genetics of HLA HLA nomenclature Evolution of HLA polymorphisms HLA associations in arthritis and rheumatology, renal disease, neurology, diabetes and endocrinology, gastroenterology, respiratory disease, ophthalmology, infections, dermatology and psychiatry HLA and organ transplantation Serological and PCR-based methods in HLA typing Cellular techniques in testing histocompatibility Edited and written by an international panel of experts in the field

Encyclopedia of Cell Biology

Author :
Publisher : Academic Press
ISBN 13 : 0123947960
Total Pages : 2972 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Encyclopedia of Cell Biology by :

Download or read book Encyclopedia of Cell Biology written by and published by Academic Press. This book was released on 2015-08-07 with total page 2972 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

The HLA FactsBook

Author : Steven G.E. Marsh
Publisher : Elsevier
ISBN 13 : 0080542506
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The HLA FactsBook by : Steven G.E. Marsh

Download or read book The HLA FactsBook written by Steven G.E. Marsh and published by Elsevier. This book was released on 1999-12-13 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references

Antigen Processing and Presentation

Author : Robert Edward Humphreys
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Antigen Processing and Presentation by : Robert Edward Humphreys

Download or read book Antigen Processing and Presentation written by Robert Edward Humphreys and published by . This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the few volumes dedicated to antigen processing, this unique text is not only especially current but also valuable for its description of petentially "hot" areas with its "Future Directions" sections. * Current, important topics covered by this text include: Processing and presentation of foreign and self protein antigens to T lymphocytes Intracellular assembley and transport of MHC proteins Regulation of the assembley and expression of processed antigen-MHC complexes

Natural History of the Major Histocompatibility Complex

Author : Jan Klein
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 820 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Natural History of the Major Histocompatibility Complex by : Jan Klein

Download or read book Natural History of the Major Histocompatibility Complex written by Jan Klein and published by Wiley-Interscience. This book was released on 1986 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is a natural history of the major histocompatibility complex written for anyone who is working on the MHC but wants to step back and review the complex in its entirety; for anyone who wants to be introduced to the MHC; or for anyone who is just curious about this much talked-about chromosomal region. By natural history is meant an all encompassing treatment of the MHC, both human and mouse, in its entire range and its details - but presented in a way that anybody can understand without consulting a variety of other sources. Most of the details are summarized in the form of tables whereas the text concentrates on generalizations and discussions. Thus, the book will be of interest to immunologists and geneticists seeking an overview of the subject and to graduate students in these disciplines. It will also be of value to technicians working in HLA-typing laboratories.

Streptococcal Superantigens

Author : Anshu Babbar
Publisher : Springer
ISBN 13 : 3319224557
Total Pages : 51 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Streptococcal Superantigens by : Anshu Babbar

Download or read book Streptococcal Superantigens written by Anshu Babbar and published by Springer. This book was released on 2015-07-24 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides ample knowledge and better understanding of Streptococcus pyogenes and their superantigens. Many illustrations make this a highly informative book. This book elucidates briefly Streptococcus pyogenes as a strict human pathogen possessing an array of virulence factors. These help in evading host immune responses such as by the activation of non-specific T-cell subpopulations by producing superantigens. This book mainly focuses on streptococcal superantigens and explains how they are different from conventional antigens. Moreover, it elaborates those diseases in which superantigens are actively involved. Useful aspects of superantigens and different therapeutic interventions to eradicate superantigens induced diseased are also discussed.

Encyclopedia of Biological Chemistry

Author :
Publisher : Elsevier
ISBN 13 : 0128220406
Total Pages : 0 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Encyclopedia of Biological Chemistry by :

Download or read book Encyclopedia of Biological Chemistry written by and published by Elsevier. This book was released on 2021-07-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Biological Chemistry, Six Volume Set has always been characterized by its unique and comprehensive content. Since publication of the 2nd edition, many important discoveries have been made leading to novel concepts in several areas of biochemistry, and new technologies have advanced our understanding of key processes of life. All of these advances are included in the new and expanded third edition. With its 6 volumes, this is the most up-to-date and complete resource on biochemistry and molecular biology, provided through contributions by leading experts in the field. A ‘one-stop’, comprehensive resource on "the chemistry of life", including a wealth of information and critical summaries to support research and teaching activities Each chapter is written concisely to guide the reader though the topic, using a consistent and unified terminology Clearly organized into seven logical sections, each curated by a world-leader in the field and the Editor in Chief

Antigen Processing

Author : Peter van Endert
Publisher : Humana Press
ISBN 13 : 9781627032179
Total Pages : 0 pages
Book Rating : 4.0/5 (321 download)

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Book Synopsis Antigen Processing by : Peter van Endert

Download or read book Antigen Processing written by Peter van Endert and published by Humana Press. This book was released on 2013-01-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antigen processing is a biological process that prepares antigens for the presentation to special cells in the immune system called T lymphocytes. In Antigen Processing: Methods and Protocols, expert researchers in the field provide a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. The chapters follow chronology of intracellular processing events, ending with recognition of peptide-MHC complexes at the cell surface by T lymphocytes. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antigen Processing: Methods and Protocols is designed for beginners and experts interested in studying antigen processing.