Molecular Neurobiology Of Addiction Recovery

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Molecular Neurobiology of Addiction Recovery

Author : Kenneth Blum
Publisher : Springer Science & Business Media
ISBN 13 : 146147230X
Total Pages : 98 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Molecular Neurobiology of Addiction Recovery by : Kenneth Blum

Download or read book Molecular Neurobiology of Addiction Recovery written by Kenneth Blum and published by Springer Science & Business Media. This book was released on 2013-05-27 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans are biologically programmed to seek out pleasurable experiences. These experiences are processed in the mesolimbic system, also referred to as the "reward center" of the brain, where a number of chemical messengers work in concert to provide a net release of dopamine in the Nucleus Accumbens. In some genetically predisposed individuals, addiction occurs when the mechanisms of the mesolimbic system are disrupted by the use of various drugs of abuse. Since Alcoholics Anonymous was founded in 1935, it's 12 step program of spiritual and character development has helped countless alcoholics and drug addicts curb their self-destructive behaviors. However, the program was developed at a time when comparatively little was known about the function of the brain and it has never been studied scientifically. This is the first book to take a systematic look at the molecular neurobiology associated with each of the 12 steps and to review the significant body of addiction research literature that is pertinent to the program.

Drugs, Addiction, and the Brain

Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0123869595
Total Pages : 351 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Drugs, Addiction, and the Brain by : George F. Koob

Download or read book Drugs, Addiction, and the Brain written by George F. Koob and published by Academic Press. This book was released on 2014-07-12 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction

Neural Mechanisms of Addiction

Author : Mary Torregrossa
Publisher : Academic Press
ISBN 13 : 0128123311
Total Pages : 308 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neural Mechanisms of Addiction by : Mary Torregrossa

Download or read book Neural Mechanisms of Addiction written by Mary Torregrossa and published by Academic Press. This book was released on 2018-08-24 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. - Transcends multiple neural, neurochemical and behavioral domains - Summarizes advances in the field of addiction research since the advent of optogenetics - Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms

Pathways of Addiction

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309175380
Total Pages : 329 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pathways of Addiction by : Institute of Medicine

Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-10-01 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

Memoirs of an Addicted Brain

Author : Marc Lewis
Publisher : Doubleday Canada
ISBN 13 : 0385669267
Total Pages : 322 pages
Book Rating : 4.3/5 (856 download)

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Book Synopsis Memoirs of an Addicted Brain by : Marc Lewis

Download or read book Memoirs of an Addicted Brain written by Marc Lewis and published by Doubleday Canada. This book was released on 2011-10-04 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A gripping, ultimately triumphant memoir that's also the most comprehensive and comprehensible study of the neuroscience of addiction written for the general public. FROM THE INTRODUCTION: "We are prone to a cycle of craving what we don't have, finding it, using it up or losing it, and then craving it all the more. This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?" The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception. Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

Neurobiology of Addiction

Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0123849756
Total Pages : 0 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Neurobiology of Addiction by : George F. Koob

Download or read book Neurobiology of Addiction written by George F. Koob and published by Academic Press. This book was released on 2025-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. - Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction - Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work - Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Biological Research on Addiction

Author :
Publisher : Academic Press
ISBN 13 : 0123983606
Total Pages : 759 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Biological Research on Addiction by :

Download or read book Biological Research on Addiction written by and published by Academic Press. This book was released on 2013-05-17 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. - Each article provides glossary, full references, suggested readings, and a list of web resources - Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available - Discusses the genetic basis of addiction - Covers basic science research from a variety of animal studies

Medications for Opioid Use Disorder Save Lives

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309486483
Total Pages : 175 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Medications for Opioid Use Disorder Save Lives by : National Academies of Sciences, Engineering, and Medicine

Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Addiction

Author : David Nutt
Publisher : Oxford University Press, USA
ISBN 13 : 0199685703
Total Pages : 102 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Addiction by : David Nutt

Download or read book Addiction written by David Nutt and published by Oxford University Press, USA. This book was released on 2013-09-26 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for psychiatrists, clinical psychologists, trainees, and specialist nurses, as well as primary care physicians/GPs with a special interest in mental health conditions and other healthcare professionals.

Addiction

Author : Gene M. Heyman
Publisher : Harvard University Press
ISBN 13 : 0674264436
Total Pages : 213 pages
Book Rating : 4.6/5 (742 download)

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Book Synopsis Addiction by : Gene M. Heyman

Download or read book Addiction written by Gene M. Heyman and published by Harvard University Press. This book was released on 2010-10-15 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a book sure to inspire controversy, Gene Heyman argues that conventional wisdom about addiction—that it is a disease, a compulsion beyond conscious control—is wrong. Drawing on psychiatric epidemiology, addicts’ autobiographies, treatment studies, and advances in behavioral economics, Heyman makes a powerful case that addiction is voluntary. He shows that drug use, like all choices, is influenced by preferences and goals. But just as there are successful dieters, there are successful ex-addicts. In fact, addiction is the psychiatric disorder with the highest rate of recovery. But what ends an addiction? At the heart of Heyman’s analysis is a startling view of choice and motivation that applies to all choices, not just the choice to use drugs. The conditions that promote quitting a drug addiction include new information, cultural values, and, of course, the costs and benefits of further drug use. Most of us avoid becoming drug dependent, not because we are especially rational, but because we loathe the idea of being an addict. Heyman’s analysis of well-established but frequently ignored research leads to unexpected insights into how we make choices—from obesity to McMansionization—all rooted in our deep-seated tendency to consume too much of whatever we like best. As wealth increases and technology advances, the dilemma posed by addictive drugs spreads to new products. However, this remarkable and radical book points to a solution. If drug addicts typically beat addiction, then non-addicts can learn to control their natural tendency to take too much.

Theory and Practice of Addiction Counseling

Author : Pamela S. Lassiter
Publisher : SAGE Publications
ISBN 13 : 1506317316
Total Pages : 653 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis Theory and Practice of Addiction Counseling by : Pamela S. Lassiter

Download or read book Theory and Practice of Addiction Counseling written by Pamela S. Lassiter and published by SAGE Publications. This book was released on 2017-02-17 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theory and Practice of Addiction Counseling by Pamela S. Lassiter and John R. Culbreth brings together contemporary theories of addiction and helps readers connect those theories to practice using a common multicultural case study. Theories covered include motivational interviewing, moral theory, developmental theory, cognitive behavioral theories, attachment theory, and sociological theory. Each chapter focuses on a single theory, describing its basic tenets, philosophical underpinnings, key concepts, and strengths and weaknesses. Each chapter also shows how practitioners using the theory would respond to a common case study, giving readers the opportunity to compare how the different theoretical approaches are applied to client situations. A final chapter discusses approaches to relapse prevention.

Author :
Publisher :
ISBN 13 : 0190275332
Total Pages : 577 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis by :

Download or read book written by and published by . This book was released on with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurobiology of Alcohol Dependence

Author : Antonio Noronha
Publisher : Elsevier
ISBN 13 : 0124071554
Total Pages : 573 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Neurobiology of Alcohol Dependence by : Antonio Noronha

Download or read book Neurobiology of Alcohol Dependence written by Antonio Noronha and published by Elsevier. This book was released on 2014-05-02 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. - Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels - Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence - Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available

Imaging of the Human Brain in Health and Disease

Author : Philip Seeman
Publisher : Elsevier
ISBN 13 : 012418684X
Total Pages : 534 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Imaging of the Human Brain in Health and Disease by : Philip Seeman

Download or read book Imaging of the Human Brain in Health and Disease written by Philip Seeman and published by Elsevier. This book was released on 2013-11-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Magnesium in the Central Nervous System

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Overcoming Your Alcohol or Drug Problem

Author : Dennis C. Daley
Publisher : Oxford University Press
ISBN 13 : 0198042035
Total Pages : 186 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Overcoming Your Alcohol or Drug Problem by : Dennis C. Daley

Download or read book Overcoming Your Alcohol or Drug Problem written by Dennis C. Daley and published by Oxford University Press. This book was released on 2006-06-15 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: A substance use problem exists when one experiences any type of difficulty related to using alcohol, tobacco, or other drugs including illicit street drugs or prescribed drugs such as painkillers or tranquilizers. The difficulty can be in any area of life; medical or physical, psychological, family, interpersonal, social, academic, occupational, legal, financial, or spiritual. This expanded new edition of the successful Graywind Publications title provides the reader with practical information and skills to help them understand and change a drug or alcohol problem. Designed to be used in conjunction with therapy or counseling, it focuses on special issues involved in stopping substance use and in changing behaviors or aspects of one's lifestyle that keep the substance use problem active. The information presented is derived from a wealth of research studies, and discusses the most effective recovery strategies from the examination of cognitive-behavoral treatment. TreatmentsThatWorkTM represents the gold standard of behavioral healthcare interventions! · All programs have been rigorously tested in clinical trials and are backed by years of research · A prestigious scientific advisory board, led by series Editor-In-Chief David H. Barlow, reviews and evaluates each intervention to ensure that it meets the highest standard of evidence so you can be confident that you are using the most effective treatment available to date · Our books are reliable and effective and make it easy for you to provide your clients with the best care available · Our corresponding workbooks contain psychoeducational information, forms and worksheets, and homework assignments to keep clients engaged and motivated · A companion website (www.oup.com/us/ttw) offers downloadable clinical tools and helpful resources · Continuing Education (CE) Credits are now available on select titles in collaboration with PsychoEducational Resources, Inc. (PER)

The Thirteenth Step

Author : Markus Heilig
Publisher : Columbia University Press
ISBN 13 : 0231539029
Total Pages : 316 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis The Thirteenth Step by : Markus Heilig

Download or read book The Thirteenth Step written by Markus Heilig and published by Columbia University Press. This book was released on 2015-05-12 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past thirty years have witnessed a revolution in the science of addiction, yet we still rely on outdated methods of treatment. Expensive new programs for managing addiction are also flourishing, but since they are not based in science, they offer little benefit to people who cannot afford to lose money or faith in their recovery. Clarifying the cutting-edge science of addiction for both practitioners and general readers, The Thirteenth Step pairs stories of real patients with explanations of key concepts relating to their illness. A police chief who disappears on the job illustrates the process through which a drug can trigger the brain circuits mediating relapse. One person's effort to find a burrito shack in a foreign city illuminates the reward prediction error signaled by the brain chemical dopamine. With these examples and more, this volume paints a vivid, readable portrait of drug seeking, escalation, and other aspects of addiction and suggests science-based treatments that promise to improve troubling relapse rates. Merging science and human experience, The Thirteenth Step offers compassionate, valuable answers to anyone who hopes for a better handle on a confounding disease.