Neurobiology Of Addiction

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Neurobiology of Addiction

Author : George F. Koob
Publisher : Elsevier
ISBN 13 : 0080497373
Total Pages : 503 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Neurobiology of Addiction by : George F. Koob

Download or read book Neurobiology of Addiction written by George F. Koob and published by Elsevier. This book was released on 2005-11-11 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

The Science of Addiction: From Neurobiology to Treatment

Author : Carlton K. Erickson
Publisher : W. W. Norton & Company
ISBN 13 : 0393704637
Total Pages : 303 pages
Book Rating : 4.3/5 (937 download)

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Book Synopsis The Science of Addiction: From Neurobiology to Treatment by : Carlton K. Erickson

Download or read book The Science of Addiction: From Neurobiology to Treatment written by Carlton K. Erickson and published by W. W. Norton & Company. This book was released on 2007-02-17 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Runner-up winner of the Hamilton Book Author Award, this book is a comprehensive overview of the neurobiology behind addictions. Neuroscience is clarifying the causes of compulsive alcohol and drug use––while also shedding light on what addiction is, what it is not, and how it can best be treated––in exciting and innovative ways. Current neurobiological research complements and enhances the approaches to addiction traditionally taken in social work and psychology. However, this important research is generally not presented in a forthright, jargon-free way that clearly illustrates its relevance to addiction professionals. The Science of Addiction presents a comprehensive overview of the roles that brain function and genetics play in addiction. It explains in an easy-to-understand way changes in the terminology and characterization of addiction that are emerging based upon new neurobiological research. The author goes on to describe the neuroanatomy and function of brain reward sites, and the genetics of alcohol and other drug dependence. Chapters on the basic pharmacology of stimulants and depressants, alcohol, and other drugs illustrate the specific and unique ways in which the brain and the central nervous system interact with, and are affected by, each of these substances Erickson discusses current and emerging treatments for chemical dependence, and how neuroscience helps us understand the way they work. The intent is to encourage an understanding of the body-mind connection. The busy clinical practitioner will find the chapter on how to read and interpret new research findings on the neurobiological basis of addiction useful and illuminating. This book will help the almost 21.6 million Americans, and millions more worldwide, who abuse or are dependent on drugs by teaching their caregivers (or them) about the latest addiction science research. It is also intended to help addiction professionals understand the foundations and applications of neuroscience, so that they will be able to better empathize with their patients and apply the science to principles of treatment.

Never Enough

Author : Judith Grisel
Publisher : Anchor
ISBN 13 : 0525434909
Total Pages : 258 pages
Book Rating : 4.5/5 (254 download)

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Book Synopsis Never Enough by : Judith Grisel

Download or read book Never Enough written by Judith Grisel and published by Anchor. This book was released on 2020-01-14 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

The Neuroscience of Addiction

Author : Francesca Mapua Filbey
Publisher : Cambridge University Press
ISBN 13 : 110712798X
Total Pages : 209 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis The Neuroscience of Addiction by : Francesca Mapua Filbey

Download or read book The Neuroscience of Addiction written by Francesca Mapua Filbey and published by Cambridge University Press. This book was released on 2019-03-14 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combines classic theories with current neuroscientific studies to explain the addiction cycle, focusing on neuroimaging studies and applications.

The Wiley Handbook on the Cognitive Neuroscience of Addiction

Author : Stephen J. Wilson
Publisher : John Wiley & Sons
ISBN 13 : 1118472241
Total Pages : 552 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis The Wiley Handbook on the Cognitive Neuroscience of Addiction by : Stephen J. Wilson

Download or read book The Wiley Handbook on the Cognitive Neuroscience of Addiction written by Stephen J. Wilson and published by John Wiley & Sons. This book was released on 2015-07-07 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a thorough and up-to-date synthesis of the expansive and highly influential literature from the last 30 years by bringing together contributions from leading authorities in the field, with emphasis placed on the most commonly investigated drugs of abuse. Emphasises the most commonly investigated drugs of abuse, including alcohol, cocaine, nicotine, and opiates Brings together the work of the leading authorities in all major areas of the field Provides novel coverage of cutting-edge methods for using cognitive neuroscience to advance the treatment of addiction, including real-time neurofeedback and brain stimulation methods Includes new material on emerging themes and future directions in the use of cognitive neuroscience to advance addiction science

Drugs, Addiction, and the Brain

Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0123869595
Total Pages : 351 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Drugs, Addiction, and the Brain by : George F. Koob

Download or read book Drugs, Addiction, and the Brain written by George F. Koob and published by Academic Press. This book was released on 2014-07-12 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Addiction Neuroethics

Author : Adrian Carter
Publisher : Cambridge University Press
ISBN 13 : 1139504673
Total Pages : 365 pages
Book Rating : 4.1/5 (395 download)

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Book Synopsis Addiction Neuroethics by : Adrian Carter

Download or read book Addiction Neuroethics written by Adrian Carter and published by Cambridge University Press. This book was released on 2011-11-17 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addiction is a significant health and social problem and one of the largest preventable causes of disease globally. Neuroscience promises to revolutionise our ability to treat addiction, lead to recognition of addiction as a 'real' disorder in need of medical treatment and thereby reduce stigma and discrimination. However, neuroscience raises numerous social and ethical challenges: • If addicted individuals are suffering from a brain disease that drives them to drug use, should we mandate treatment? • Does addiction impair an individual's ability to consent to research or treatment? • How will neuroscience affect social policies towards drug use? Addiction Neuroethics addresses these challenges by examining ethical implications of emerging neurobiological treatments, including: novel psychopharmacology, neurosurgery, drug vaccines to prevent relapse, and genetic screening to identify individuals who are vulnerable to addiction. Essential reading for academics, clinicians, researchers and policy-makers in the fields of addiction, mental health and public policy.

Drugs, Brains, and Behavior

Author :
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Drugs, Brains, and Behavior by :

Download or read book Drugs, Brains, and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neural Mechanisms of Addiction

Author : Mary Torregrossa
Publisher : Academic Press
ISBN 13 : 0128123311
Total Pages : 306 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neural Mechanisms of Addiction by : Mary Torregrossa

Download or read book Neural Mechanisms of Addiction written by Mary Torregrossa and published by Academic Press. This book was released on 2018-08-24 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. Transcends multiple neural, neurochemical and behavioral domains Summarizes advances in the field of addiction research since the advent of optogenetics Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms

The Neurobiology of Addiction

Author : Trevor W. Robbins
Publisher :
ISBN 13 : 0199562156
Total Pages : 327 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis The Neurobiology of Addiction by : Trevor W. Robbins

Download or read book The Neurobiology of Addiction written by Trevor W. Robbins and published by . This book was released on 2010 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades, there have been astonishing advances in our understanding of the neurobiological basis and nature of drug addiction. We now know the initial molecular sites of action, at identified receptors, of virtually all of the major drugs of abuse including cocaine, heroin, and amphetamine, as well as legal drugs such as nicotine and alcohol. We also understand the main components of a 'reward system' and its connections to major brain regions involved in motivation and emotion, such as the amygdala, hippocampus, and prefrontal cortex. The Neurobiology of Addiction describes the latest advances in our understanding of addiction. It brings together world class researchers to debate the nature and extent of addiction, as well as its causes, consequences, and treatment. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine. In addition, it explores increasingly common behavioural addictions such as gambling and obesity. Included are chapters on vulnerability to addiction, genetic factors, opponent motivational processes, animal models, relapse, cognitive deficits associated with drug abuse, new pharmacological treatments, and current controversies concerning different neuropsychological theories of addiction. Throughout, it reports on cutting edge research using brain imaging, and state of the art molecular methodology. The book will make fascinating reading for students and teachers in the field of neuroscience, pharmacology and psychology, as well as experts in the field.

Alcohol

Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0128167947
Total Pages : 402 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Alcohol by : George F. Koob

Download or read book Alcohol written by George F. Koob and published by Academic Press. This book was released on 2021-07-07 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Alcohol, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol

Addiction Mechanisms, Phenomenology and Treatment

Author : W.W. Fleischhacker
Publisher : Springer Science & Business Media
ISBN 13 : 3709105412
Total Pages : 154 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Addiction Mechanisms, Phenomenology and Treatment by : W.W. Fleischhacker

Download or read book Addiction Mechanisms, Phenomenology and Treatment written by W.W. Fleischhacker and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Substance-related disorders pose an increasing challenge not only to the field of psychiatry but also to public health. The rapid development of our society has also changed the face of substance use and abuse, both quantitatively and qualitatively. In this volume international experts present reviews of the latest research covering many areas ranging from neurobiology to psychological management, as well as different drugs, from alcohol to ecstasy.

Dispelling the Myths About Addiction

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309174597
Total Pages : 236 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Dispelling the Myths About Addiction by : Institute of Medicine

Download or read book Dispelling the Myths About Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1997-11-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year about half a million men, women, and children in the United States die from the effects of using nicotine, alcohol, and illegal drugs: one of every four American deaths. Yet research to solve this terrible problem is often perceived as less important than other types of biomedical investigation. Focusing on four major classes of drugs with the greatest social and economic impactâ€"nicotine, alcohol, opioids, and stimulantsâ€"Dispelling the Myths About Addiction examines what is known about addiction and what is needed to develop a talented cadre of investigators and to educate the public about addiction research. The committee explores these areas: Economic costs of addiction. What has been learned about addiction from research into basic neurobiology and the brain, psychosocial and behavioral factors, and epidemiology. Education and training of researchers and the research infrastructure. Public perceptions and their impact on public policy in this field. This volume outlines the challenges and opportunities in addiction research today and makes recommendations to educators, treatment professionals, public and private institutions, and others for how to build support for addiction research and treatment.

Behavioral Neuroscience of Drug Addiction

Author : David W. Self
Publisher : Springer Science & Business Media
ISBN 13 : 3642030017
Total Pages : 392 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Behavioral Neuroscience of Drug Addiction by : David W. Self

Download or read book Behavioral Neuroscience of Drug Addiction written by David W. Self and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.

Neurobiology of Alcohol and the Brain

Author : Ashok K. Singh
Publisher : Academic Press
ISBN 13 : 0128196807
Total Pages : 364 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neurobiology of Alcohol and the Brain by : Ashok K. Singh

Download or read book Neurobiology of Alcohol and the Brain written by Ashok K. Singh and published by Academic Press. This book was released on 2020-10-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the 2018 National Survey on Drug Use and Health, 14.4 million adults aged 18 and older had alcohol use disorder (AUD). Mixing alcohol with other drugs such as opioids or cocaine has become an emerging trend, exacerbating public health concerns and may synergistically augment the seriousness of the adverse effects such as withdrawal symptoms, cardiovascular disorders, liver damage, reproductive abnormalities, and behavioral abnormalities. Despite the seriousness of the situation, possible mechanisms underlying the addiction and the withdrawal symptoms is not yet understood. This has been one of the key hindrances in developing effective treatment. Neurobiology of Alcohol and the Brain addresses the addiction-related problems reviewing both the mechanisms and withdrawal system with alcohol addiction. First, the book discusses the mechanisms of the rewarding and aversive effects, including addiction and the withdrawal symptoms of alcohol drinking. Next, alcohol's interaction with other drugs and ensuing adverse consequences is discussed including current and novel treatments against alcoholism. This is followed by a closer look at mental health and alcohol use disorder comorbidity. Lastly, the reader is provided with examples of an experimental study that describes possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Neurobiology of Alcohol and the Brain will unlock the mechanistic diversities of alcoholism helping to facilitate future developments of new, personalized treatment options for patients suffering from alcohol addiction. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Facing Addiction in America

Author : Office of the Surgeon General
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781974580620
Total Pages : 420 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis Facing Addiction in America by : Office of the Surgeon General

Download or read book Facing Addiction in America written by Office of the Surgeon General and published by Createspace Independent Publishing Platform. This book was released on 2017-08-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.

Neurobiology of Addiction

Author : Alan C. Swann
Publisher : Oxford University Press, USA
ISBN 13 : 9780199367894
Total Pages : 0 pages
Book Rating : 4.3/5 (678 download)

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Book Synopsis Neurobiology of Addiction by : Alan C. Swann

Download or read book Neurobiology of Addiction written by Alan C. Swann and published by Oxford University Press, USA. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Addiction highlights some of the most promising research areas of the rapidly expanding field of addiction. It will be useful as a practical tool for clinicians, research investigators, and trainees-both in addiction and in other illnesses with overlapping mechanisms-as well as an informative resource for non-technical readers who are interested in addiction or mental health policy. The editors have combined their areas of expertise to provide a unique perspective into the prevention and treatment of addictive disorders. Their approach addresses addiction in the broader context of behavioral processes and survival-related adaptations, focusing on its neurobiological precursors and drawing parallels between addictions and other recurrent or progressive psychiatric disorders. The book also emphasizes resilience, clinical contexts of addictive behavior, and treatment strategies that target its underlying neurobiological mechanisms.