Molecular Imaging Of Small Animals

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Small Animal Imaging

Author : Fabian Kiessling
Publisher : Springer
ISBN 13 : 3319422022
Total Pages : 875 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Small Animal Imaging by : Fabian Kiessling

Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer. This book was released on 2017-05-22 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.

Molecular Imaging of Small Animals

Author : Habib Zaidi
Publisher : Springer
ISBN 13 : 1493908944
Total Pages : 760 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Molecular Imaging of Small Animals by : Habib Zaidi

Download or read book Molecular Imaging of Small Animals written by Habib Zaidi and published by Springer. This book was released on 2014-05-27 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

Handbook of Small Animal Imaging

Author : George C. Kagadis
Publisher : CRC Press
ISBN 13 : 131536042X
Total Pages : 1080 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Handbook of Small Animal Imaging by : George C. Kagadis

Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2018-09-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

Small Animal Imaging

Author : Fabian Kiessling
Publisher : Springer Science & Business Media
ISBN 13 : 3642129455
Total Pages : 597 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Small Animal Imaging by : Fabian Kiessling

Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer Science & Business Media. This book was released on 2010-11-29 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small animal imaging has been recognized as an important tool in preclinical research. Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of a suboptimal imaging modality and/or shortcomings in study design, experimental setup, and data evaluation. This textbook is a practical guide to the use of non-invasive imaging in preclinical research. Each of the available imaging modalities is discussed in detail, with the assistance of numerous informative illustrations. In addition, many useful hints are provided on the installation of a small animal unit, study planning, animal handling, and the cost-effective performance of small animal imaging. Cross-calibration methods, data postprocessing, and special imaging applications are also considered in depth. This is the first book to cover all the practical basics in small animal imaging, and it will prove an invaluable aid for researchers, students, and technicians.

Small-Animal SPECT Imaging

Author : Matthew A. Kupinski
Publisher : Springer Science & Business Media
ISBN 13 : 0387252940
Total Pages : 294 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Small-Animal SPECT Imaging by : Matthew A. Kupinski

Download or read book Small-Animal SPECT Imaging written by Matthew A. Kupinski and published by Springer Science & Business Media. This book was released on 2007-05-27 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.

Targeted Molecular Imaging

Author : Michael J. Welch
Publisher : CRC Press
ISBN 13 : 1439841950
Total Pages : 390 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Targeted Molecular Imaging by : Michael J. Welch

Download or read book Targeted Molecular Imaging written by Michael J. Welch and published by CRC Press. This book was released on 2012-02-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.

Molecular Imaging

Author : Ralph Weissleder
Publisher : PMPH-USA
ISBN 13 : 9781607950059
Total Pages : 1384 pages
Book Rating : 4.9/5 (5 download)

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Book Synopsis Molecular Imaging by : Ralph Weissleder

Download or read book Molecular Imaging written by Ralph Weissleder and published by PMPH-USA. This book was released on 2010 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Molecular Imaging

Author : Shankar Vallabhajosula
Publisher : Springer Science & Business Media
ISBN 13 : 3540767355
Total Pages : 379 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Molecular Imaging by : Shankar Vallabhajosula

Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Small animal imaging: Technological and methodological advances to improve the translational power

Author : Monique R. Bernsen
Publisher : Frontiers Media SA
ISBN 13 : 2832511384
Total Pages : 152 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Small animal imaging: Technological and methodological advances to improve the translational power by : Monique R. Bernsen

Download or read book Small animal imaging: Technological and methodological advances to improve the translational power written by Monique R. Bernsen and published by Frontiers Media SA. This book was released on 2023-01-13 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emission Tomography

Author : Miles N. Wernick
Publisher : Elsevier
ISBN 13 : 9780080521879
Total Pages : 596 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Emission Tomography by : Miles N. Wernick

Download or read book Emission Tomography written by Miles N. Wernick and published by Elsevier. This book was released on 2004-12-07 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: PET and SPECT are two of today’s most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world’s fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging. *Contains thorough tutorial treatments, coupled with coverage of advanced topics *Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors *Include color artwork

Molecular Imaging

Author : Brian D. Ross
Publisher : Academic Press
ISBN 13 : 0128163879
Total Pages : 1872 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Molecular Imaging by : Brian D. Ross

Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Molecular Imaging in Oncology

Author : Martin G. Pomper
Publisher : CRC Press
ISBN 13 : 1000654400
Total Pages : 762 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Molecular Imaging in Oncology by : Martin G. Pomper

Download or read book Molecular Imaging in Oncology written by Martin G. Pomper and published by CRC Press. This book was released on 2008-10-13 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: With molecular imaging becoming one the fastest growing topics in medical schools, Informa Healthcare presents Molecular Imaging in Oncology, the first comprehensive reference on molecular imaging in oncology.Giving clinicians and researchers a greater understanding of the current field, this text covers:instrumentation and techniquescancer imaging

Biophysical Techniques in Drug Discovery

Author : Angeles Canales
Publisher : Royal Society of Chemistry
ISBN 13 : 1788012860
Total Pages : 336 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Biophysical Techniques in Drug Discovery by : Angeles Canales

Download or read book Biophysical Techniques in Drug Discovery written by Angeles Canales and published by Royal Society of Chemistry. This book was released on 2017-11-14 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysical techniques are used in many key stages of the drug discovery process including in screening for new receptor ligands, in characterising drug mechanisms, and in validating data from biochemical and cellular assays. This book provides an overview of the biophysical methods applied in drug discovery today, including traditional techniques and newer developments. Perspectives from academia and industry across a spectrum of techniques are brought together in a single volume. Small and biotherapeutic approaches are covered and strengths and limitations of each technique are presented. Case studies illustrate the application of each technique in real applied examples. Finally, the book covers recent developments in areas such as electron microscopy with discussions of their possible impact on future drug discovery. This is a go-to volume for biophysicists, analytical chemists and medicinal chemists providing a broad overview of techniques of contemporary interest in drug discovery.

Targeted Molecular Imaging

Author : Michael J. Welch
Publisher : Taylor & Francis
ISBN 13 : 1439841969
Total Pages : 388 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Targeted Molecular Imaging by : Michael J. Welch

Download or read book Targeted Molecular Imaging written by Michael J. Welch and published by Taylor & Francis. This book was released on 2012-02-24 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.

Handbook of Small Animal Imaging

Author : George C. Kagadis
Publisher : CRC Press
ISBN 13 : 1315362791
Total Pages : 602 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Handbook of Small Animal Imaging by : George C. Kagadis

Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2018-09-03 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

Molecular Imaging

Author : Jie Tian
Publisher : Springer Science & Business Media
ISBN 13 : 3642343031
Total Pages : 699 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Molecular Imaging by : Jie Tian

Download or read book Molecular Imaging written by Jie Tian and published by Springer Science & Business Media. This book was released on 2013-07-23 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.

Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy

Author : Yuji Kuge
Publisher : Springer
ISBN 13 : 4431558942
Total Pages : 326 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy by : Yuji Kuge

Download or read book Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy written by Yuji Kuge and published by Springer. This book was released on 2016-04-02 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.