Molecular Epidemiology of Prostate Cancer Progression

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Molecular Epidemiology of Prostate Cancer Progression by : Meda R. Sandu

Download or read book Molecular Epidemiology of Prostate Cancer Progression written by Meda R. Sandu and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This note is part of Quality testing.

Molecular Epidemiology of Prostate Cancer

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ISBN 13 :
Total Pages : 15 pages
Book Rating : 4.:/5 (742 download)

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Book Synopsis Molecular Epidemiology of Prostate Cancer by :

Download or read book Molecular Epidemiology of Prostate Cancer written by and published by . This book was released on 2004 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the Final Report for this project. It provides new updated information since the last report, which was submitted in June 2004, and provides an overall summary of progress, and remaining steps required to meet the study objectives. Although those objectives were not completed during the funding period, they will be completed using other funding sources. The objective of this case-control study is to determine whether oxidative damage is a risk factor for prostate cancer, and whether this mechanism mediates the association between dietary fat and prostate cancer risk. Specifically, cases and controls will be compared with respect to malondialdehyde (MDA) in serum as a measure of oxidative stress, and deoxyguanosine malondialdehyde (dG-MDA) in peripheral lymphocytes and prostate tumor samples as a measure of oxidative DNA damage. In addition to these measures, dietary intake of fats and specific fatty acids, and of antioxidants will be considered as potential effect modifiers or confounding factors, as will serum antioxidant levels. Enrollment of cases and controls, collection of questionnaire data, and collection of serum, plasma and lymphocytes has been completed.

Male Reproductive Cancers

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Publisher : Springer Science & Business Media
ISBN 13 : 1441904492
Total Pages : 347 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Male Reproductive Cancers by : William D. Foulkes

Download or read book Male Reproductive Cancers written by William D. Foulkes and published by Springer Science & Business Media. This book was released on 2009-12-17 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about cancer genetics is rapidly expanding, and has implications for all aspects of cancer research and treatment, including molecular causation, diagnosis, prevention, screening, and treatment. Additionally, while cancer genetics has traditionally focused on mutational events that have their primary effect within the cancer cell, recently the focus has widened, with evidence of the importance of epigenetic events and of cellular interactions in cancer development. The role of common genetic variation in determining the range of individual susceptibility within the population is increasingly recognized, and is now being widely addressed using information from the Human Genome Project. These new research directions will highlight determinants of cancer that lie outside the cancer cell, suggest new targets for intervention, and inform the design of strategies for prevention in groups at increased risk. Today, the NCI is putting more and more money into research into the genetics of cancer. The very first of the NCI’s stated research priorities is a project called The Cancer Genome Atlas. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. The NCI and the NHGRI (National Human Genome Research Institute, where the series editor is employed) have each committed $50 million over three years to the TCGA Pilot Project. This book proposes cover the latest findings in the genetics of male reproductive cancers; specifically cancers of the prostate and testes. The volume will cover the epidemiology of these cancers; model systems, pathology, molecular genetics, and inherited susceptibility.

Studies of the Genetic Epidemiology and Molecular Genetics of Human Prostate Cancer

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ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.:/5 (279 download)

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Book Synopsis Studies of the Genetic Epidemiology and Molecular Genetics of Human Prostate Cancer by : Bob S. Carter

Download or read book Studies of the Genetic Epidemiology and Molecular Genetics of Human Prostate Cancer written by Bob S. Carter and published by . This book was released on 1992 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Genetic Epidemiology of Prostate Cancer

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ISBN 13 :
Total Pages : 62 pages
Book Rating : 4.:/5 (568 download)

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Book Synopsis The Genetic Epidemiology of Prostate Cancer by : Mark Kozicky

Download or read book The Genetic Epidemiology of Prostate Cancer written by Mark Kozicky and published by . This book was released on 2008 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pathology and Epidemiology of Cancer

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Publisher : Springer
ISBN 13 : 3319351532
Total Pages : 664 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Pathology and Epidemiology of Cancer by : Massimo Loda

Download or read book Pathology and Epidemiology of Cancer written by Massimo Loda and published by Springer. This book was released on 2016-09-01 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book integrates the disciplines of cancer pathology and epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the diagnostic, prognostic and predictive molecular pathology of cancer. Epidemiological studies, including descriptive epidemiology, risk factors and molecular mechanisms of disease inform on the etiology and progression of cancer. The text concentrates on major cancers that are currently prevalent and those for which substantial molecular, pathological and epidemiological data is available. Each section is designed to provide an overview of that cancer type in terms of basic biology, review the current epidemiological data surrounding that cancer type and provide information on common practices and challenges related to the molecular pathology of that cancer type. Several relevant techniques in molecular pathology, which facilitate diagnosis and treatment are also explored. Pathology and Epidemiology of Cancer provides a succinct and comprehensive overview of multiple cancer types to guide clinicians during patient care and to guide scientists for innovations in research. It represents an integral resource for pathologists, epidemiologists, medical students as well as translational, basic and clinical science researchers who are all working to progress the field of cancer in terms of diagnosis, treatment and prevention.

Mechanisms of Carcinogenesis

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Patricia A. Buffler

Download or read book Mechanisms of Carcinogenesis written by Patricia A. Buffler and published by World Health Organization. This book was released on 2004 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, molecular epidemiology has become an important discipline in cancer research. It has evolved towards the development, validation and application of markers of susceptibility and, more recently, markers of mechanisms of cancer development. This volume on mechanisms of carcinogenesis covers from an interdisciplinary perspective, the contribution of molecular epidemiology to the understanding of mechanisms of carcinogenesis, and represents a further contribution to the development of molecular epidemiology as a major cancer research domain.

Genetic Epidemiology of Prostate Cancer Statistical Analyses of Genome-wide Association Studies of Prostate Cancer

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Genetic Epidemiology of Prostate Cancer Statistical Analyses of Genome-wide Association Studies of Prostate Cancer by : Seyed Ali Amin Al Olama

Download or read book Genetic Epidemiology of Prostate Cancer Statistical Analyses of Genome-wide Association Studies of Prostate Cancer written by Seyed Ali Amin Al Olama and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Epidemiology

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Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Genetic Epidemiology of Prostate Cancer

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Publisher :
ISBN 13 : 9789173056694
Total Pages : 62 pages
Book Rating : 4.0/5 (566 download)

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Book Synopsis Genetic Epidemiology of Prostate Cancer by : Fredrik Wiklund

Download or read book Genetic Epidemiology of Prostate Cancer written by Fredrik Wiklund and published by . This book was released on 2004 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Prostate Cancer

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Publisher : Springer Nature
ISBN 13 : 303032656X
Total Pages : 483 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Prostate Cancer by : Scott M. Dehm

Download or read book Prostate Cancer written by Scott M. Dehm and published by Springer Nature. This book was released on 2020-01-03 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.

Cancer Epidemiology

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Publisher : Oxford University Press, USA
ISBN 13 : 0199733503
Total Pages : 443 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Cancer Epidemiology by : Amr Soliman

Download or read book Cancer Epidemiology written by Amr Soliman and published by Oxford University Press, USA. This book was released on 2013-07-18 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization's 2008 GLOBOCAN report, 64% of global cancer deaths — and 56% of cancer cases — were registered in countries in Africa, Asia, or Latin America. So while cancer is unquestionably a global burden, its reach in the developing world points to the need for specialized study on cancer in these countries. Cancer Epidemiology: Low- and Middle-Income Countries and Special Populations reviews the current status of cancer epidemiologic research and training — rationale, requisite infrastructure, methodologic principles, and illustrative examples in low- and middle-income countries — in order to facilitate future advances by trained health professionals. The result is a valuable resource for both program leaders and graduate and post-graduate students pursuing careers in international cancer epidemiologic research.

Molecular Subclassification of Prostate Cancer

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ISBN 13 :
Total Pages : 178 pages
Book Rating : 4.:/5 (881 download)

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Book Synopsis Molecular Subclassification of Prostate Cancer by : Rebecca Elizabeth Graff

Download or read book Molecular Subclassification of Prostate Cancer written by Rebecca Elizabeth Graff and published by . This book was released on 2014 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Quick Guide to Cancer Epidemiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3319050680
Total Pages : 110 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis A Quick Guide to Cancer Epidemiology by : Paolo Boffetta

Download or read book A Quick Guide to Cancer Epidemiology written by Paolo Boffetta and published by Springer Science & Business Media. This book was released on 2014-03-22 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Quick Guide to Cancer Epidemiology is an ideal addition to Springer Briefs in Cancer Research. The Brief provides core concepts in cancer epidemiology and also gives a snapshot of the epidemiology of seventeen human cancers. The Brief aims to provide-with quantitative focus-estimates of the global burden of neoplasms, of recent and likely future trends, distribution, causes and strategies for prevention for major groups of cancers. Finally, the Brief will give an overview of severals factors that cause cancer including dietary factors, tobacco smoking, obesity and alcohol consumption.

Precision Molecular Pathology of Prostate Cancer

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Publisher : Springer
ISBN 13 : 3319640968
Total Pages : 564 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Precision Molecular Pathology of Prostate Cancer by : Brian D. Robinson

Download or read book Precision Molecular Pathology of Prostate Cancer written by Brian D. Robinson and published by Springer. This book was released on 2018-02-13 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the following: (1) General principles; (2) Molecular signatures of primary prostate cancer; (3) Molecular signatures of advanced prostate cancer; (4) Key molecular pathways in prostate cancer development and progression; (5) and Precision medicine approach: Diagnosis, treatment, prognosis. Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.

Genetic Epidemiology of Prostate Cancer

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Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Genetic Epidemiology of Prostate Cancer by :

Download or read book Genetic Epidemiology of Prostate Cancer written by and published by . This book was released on 2007 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer results from complex interactions among genetic, endocrine, and environmental factors. Understanding genetic risk factors that contribute to the occurrence of prostate cancer is crucial to design both preventative and therapeutic strategies and to identify at-risk individuals. Plausible candidates for susceptibility genes for prostate cancer risk include genes involved in insulin-like growth factor signaling, androgen signaling, and in immune response. We hypothesized that genetic variation in genes in these pathways was associated with prostate cancer risk. We studied 199 incident prostate cancer cases and 263 age-matched controls. Genotyping was performed for 59 polymorphisms in 18 genes and statistical analyses performed to look at their associations with prostate cancer risk and aggressiveness. As previously reported, the IRS1 G972R GR/RR genotypes (rs1801278) were associated with a significant 2.7-fold increased risk for prostate cancer (95% CI 1.5-4.9, p=0.0007). Other significant results were SNP rs2139924 in IGF1R with a 2.6-fold increased risk (95% CI 1.1-6.5) and rs361072 in PI3KCB with a 1.6 fold increased risk (95% CI 1.03-1.66). These results support a role of the insulin-like growth factor pathway in the etiology of prostate cancer. These results need to be replicated in multiple, larger studies.

Cancer Epidemiology and Prevention

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Publisher : Oxford University Press
ISBN 13 : 0190238674
Total Pages : 1329 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Cancer Epidemiology and Prevention by : Michael Thun

Download or read book Cancer Epidemiology and Prevention written by Michael Thun and published by Oxford University Press. This book was released on 2017-11-07 with total page 1329 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology "Practitioners in epidemiology and oncology will find immense value in this." -JAMA Since its initial publication in 1982, CANCER EPIDEMIOLOGY AND PREVENTION has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans. Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. New and timely chapters on environmental and social-epidemiologic factors include: · The role of social class disparities · The role of obesity and physical inactivity · The potential effects of electromagnetic fields and radiofrequency radiation · The principles of cancer chemoprevention For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authority in the field -- a work of distinction that every lab, library, student, professional, or researcher should have close at hand.