Molecular Biology of the SARS-Coronavirus

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Publisher : Springer Science & Business Media
ISBN 13 : 364203683X
Total Pages : 328 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Molecular Biology of the SARS-Coronavirus by : Sunil K. Lal

Download or read book Molecular Biology of the SARS-Coronavirus written by Sunil K. Lal and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: SARS was the ?rst new plague of the twenty-?rst century. Within months, it spread worldwide from its “birthplace” in Guangdong Province, China, affecting over 8,000 people in 25 countries and territories across ?ve continents. SARS exposed the vulnerability of our modern globalised world to the spread of a new emerging infection. SARS (or a similar new emerging disease) could neither have spread so rapidly nor had such a great global impact even 50 years ago, and arguably, it was itself a product of our global inter-connectedness. Increasing af?uence and a demand for wild-game as exotic food led to the development of large trade of live animal and game animal markets where many species of wild and domestic animals were co-housed, providing the ideal opportunities for inter-species tra- mission of viruses and other microbes. Once such a virus jumped species and attacked humans, the increased human mobility allowed the virus the opportunity for rapid spread. An infected patient from Guangdong who stayed for one day at a hotel in Hong Kong led to the transmission of the disease to 16 other guests who travelled on to seed outbreaks of the disease in Toronto, Singapore, and Vietnam, as well as within Hong Kong itself. The virus exploited the practices used in modern intensive care of patients with severe respiratory disease and the weakness in infection control practices within our health care systems to cause outbreaks within hospitals, further amplifying the spread of the disease. Health-care itself has become a two-edged sword.

Coronaviruses

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Publisher :
ISBN 13 : 9781912530359
Total Pages : 0 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Coronaviruses by : Volker Thiel

Download or read book Coronaviruses written by Volker Thiel and published by . This book was released on 2020-01-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paperback. ISBN 978-1-912530-35-9. In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. Essential reading for all coronavirologists as well as scientists working on other viruses of the respiratory and/or gastrointestinal tract.

The COVID-19 Pandemic: Epidemiology, Molecular Biology and Therapy

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9811481857
Total Pages : 276 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis The COVID-19 Pandemic: Epidemiology, Molecular Biology and Therapy by : Shama Parveen

Download or read book The COVID-19 Pandemic: Epidemiology, Molecular Biology and Therapy written by Shama Parveen and published by Bentham Science Publishers. This book was released on 2021-02-01 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Coronavirus Disease 2019 (COVID-19) pandemic has affected almost every part of the globe with millions of cases and over a million deaths. The pandemic has had a significant global economic impact and addressing it systematically requires significant efforts from researchers, healthcare workers and governments. The COVID-19 Pandemic covers relevant aspects of this viral pandemic including information about the SARS-CoV-2 pathogen (morphology, genome, proteins, structural protein genes, replication), global epidemiology, transmission, risk factors, clinical manifestation, management, host immune response, pathogenesis, diagnosis and therapeutic agents (antivirals, natural compounds and vaccines). Readers will find basic and advanced knowledge about the disease organized into simple and easy-to-read chapters about the disease, making this book a handy and comprehensive reference for general readers, academics and biology students, alike.

Coronaviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 1461529964
Total Pages : 462 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Coronaviruses by : Hubert Laude

Download or read book Coronaviruses written by Hubert Laude and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.

SARS- and Other Coronaviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 9781588298676
Total Pages : 368 pages
Book Rating : 4.2/5 (986 download)

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Book Synopsis SARS- and Other Coronaviruses by : Dave Cavanagh

Download or read book SARS- and Other Coronaviruses written by Dave Cavanagh and published by Springer Science & Business Media. This book was released on 2008-09-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2003, the word "coronavirus" spread across the globe, somewhat further than the virus that sparked the panic. In this book, expert researchers examine these devastating viruses through 23 state-of-the-art, widely applicable protocols with minute detail. Comprehensive and cutting-edge, the book serves as an ideal guide for all virologists and especially for those working with coronaviruses. Written by international experts, this book is relevant to a wide array of professions.

Coronaviruses

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Publisher :
ISBN 13 : 9781912530342
Total Pages : pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Coronaviruses by : Volker Thiel

Download or read book Coronaviruses written by Volker Thiel and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. The book is divided into two sections: Part I focuses on the molecular biology of the virus itself and includes topics such as coronavirus binding and entry, replicase gene function, cis-acting RNA elements, coronavirus discontinuous transcription, reverse genetics, genome packaging and molecular evolution. In Part II of the book, the focus is on molecular and cellu.

Clinical, Biological and Molecular Aspects of COVID-19

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Publisher : Springer Nature
ISBN 13 : 3030592618
Total Pages : 356 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Clinical, Biological and Molecular Aspects of COVID-19 by : Paul C. Guest

Download or read book Clinical, Biological and Molecular Aspects of COVID-19 written by Paul C. Guest and published by Springer Nature. This book was released on 2021-03-03 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines. This new volume will increase readers’ understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

Learning from SARS

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Publisher : National Academies Press
ISBN 13 : 0309182158
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Learning from SARS by : Institute of Medicine

Download or read book Learning from SARS written by Institute of Medicine and published by National Academies Press. This book was released on 2004-04-26 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of severe acute respiratory syndrome (SARS) in late 2002 and 2003 challenged the global public health community to confront a novel epidemic that spread rapidly from its origins in southern China until it had reached more than 25 other countries within a matter of months. In addition to the number of patients infected with the SARS virus, the disease had profound economic and political repercussions in many of the affected regions. Recent reports of isolated new SARS cases and a fear that the disease could reemerge and spread have put public health officials on high alert for any indications of possible new outbreaks. This report examines the response to SARS by public health systems in individual countries, the biology of the SARS coronavirus and related coronaviruses in animals, the economic and political fallout of the SARS epidemic, quarantine law and other public health measures that apply to combating infectious diseases, and the role of international organizations and scientific cooperation in halting the spread of SARS. The report provides an illuminating survey of findings from the epidemic, along with an assessment of what might be needed in order to contain any future outbreaks of SARS or other emerging infections.

Molecular Biology and Pathogenesis of Coronaviruses

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Publisher : Springer Science & Business Media
ISBN 13 : 1461593735
Total Pages : 408 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular Biology and Pathogenesis of Coronaviruses by : P. J. Rottier

Download or read book Molecular Biology and Pathogenesis of Coronaviruses written by P. J. Rottier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the Institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today - to be constructed from essentially three polypeptides - to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, - to generate these subgenomic RNAs through specific fusion of non contiguous sequences, - to mature by budding from intracellular membranes, - to cause persistent infection with neurological involvement and sometimes immunopathological conditons. These and many other findings have been established only very recently. The articles collected in this book reveal and/or further detail these findings. Since these Proceedings contain the combined scientific presentations of representatives from virtually all laboratories engaged in the field, they provide a fairly comprehensive review of the state of the art in corona virology.

Understanding Coronavirus

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Publisher : Cambridge University Press
ISBN 13 : 1009086650
Total Pages : 167 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Understanding Coronavirus by : Raul Rabadan

Download or read book Understanding Coronavirus written by Raul Rabadan and published by Cambridge University Press. This book was released on 2021-10-14 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the identification of the first cases of the coronavirus in December 2019, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the virus, unproven therapies, and inconsistent public health measures, have all served to increase anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? In this concise and accessible introduction, a leading expert provides answers to these commonly asked questions. This revised and updated edition now also covers how the virus mutates, how important these mutations are, how vaccines work, and what we can expect in the near and long-term future.

Molecular Biology of Sars-Cov-2

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Publisher :
ISBN 13 : 9781975231323
Total Pages : 0 pages
Book Rating : 4.2/5 (313 download)

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Book Synopsis Molecular Biology of Sars-Cov-2 by : HASELTINE

Download or read book Molecular Biology of Sars-Cov-2 written by HASELTINE and published by . This book was released on 2024-07-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2

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Publisher : National Academies Press
ISBN 13 : 0309680948
Total Pages : 111 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2 by : National Academies of Sciences, Engineering, and Medicine

Download or read book Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2 written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-09-29 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December 2019, new cases of severe pneumonia were first detected in Wuhan, China, and the cause was determined to be a novel beta coronavirus related to the severe acute respiratory syndrome (SARS) coronavirus that emerged from a bat reservoir in 2002. Within six months, this new virusâ€"SARS coronavirus 2 (SARS-CoV-2)â€"has spread worldwide, infecting at least 10 million people with an estimated 500,000 deaths. COVID-19, the disease caused by SARS-CoV-2, was declared a public health emergency of international concern on January 30, 2020 by the World Health Organization (WHO) and a pandemic on March 11, 2020. To date, there is no approved effective treatment or vaccine for COVID-19, and it continues to spread in many countries. Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2: Modernizing Pandemic Response Strategies lays out a framework to define and describe the data needs for a system to track and correlate viral genome sequences with clinical and epidemiological data. Such a system would help ensure the integration of data on viral evolution with detection, diagnostic, and countermeasure efforts. This report also explores data collection mechanisms to ensure a representative global sample set of all relevant extant sequences and considers challenges and opportunities for coordination across existing domestic, global, and regional data sources.

Corona- and Related Viruses

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Publisher : Springer Science & Business Media
ISBN 13 : 1461518997
Total Pages : 592 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Corona- and Related Viruses by : Gary A. Levy

Download or read book Corona- and Related Viruses written by Gary A. Levy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corona- and related viruses are important human and animal pathogens that also serve as models for other viral-mediated diseases. Interest in these pathogens has grown tremendously since the First International Symposium was held at the Institute of Virology and Immunobiology of the University of Wiirzburg, Germany. The Sixth International Symposium was held in Quebec City from August 27 to September I, 1994, and provided further understanding of the molecular biology, immunology, and pathogenesis of corona-, toro-, and arterivirus infections. Lectures were given on the molecular biology, pathogenesis, immune responses, and development of vaccines. Studies on the pathogenesis of coronavirus infections have been focused mainly on murine coronavirus, and mouse hepatitis virus. Neurotropic strains ofMHV (e.g., JHM, A59) cause a demyelinating disease that has served as an animal model for human multiple sclerosis. Dr. Samuel Dales, of the University of Western Ontario, London, Canada, gave a state-of-the-art lecture on our current under standing of the pathogenesis of JHM-induced disease.

Coronavirus Replication and Reverse Genetics

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540214946
Total Pages : 278 pages
Book Rating : 4.2/5 (149 download)

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Book Synopsis Coronavirus Replication and Reverse Genetics by : Luis Enjuanes

Download or read book Coronavirus Replication and Reverse Genetics written by Luis Enjuanes and published by Springer Science & Business Media. This book was released on 2004-10-05 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

SARS-CoV-2

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Publisher : Humana
ISBN 13 : 9781071621134
Total Pages : 0 pages
Book Rating : 4.6/5 (211 download)

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Book Synopsis SARS-CoV-2 by : Justin Jang Hann Chu

Download or read book SARS-CoV-2 written by Justin Jang Hann Chu and published by Humana. This book was released on 2023-05-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume provides the increasing number of SARS-CoV-2 researchers with a useful handbook covering multidisciplinary approaches on various aspects of SARS-CoV-2 research, brought together by leading laboratories across the globe. Topics covered include techniques in clinical and diagnostic virology, basic protocols in cell and virus culture, as well as bioinformatics and proteomics approaches in cellular response studies. This comprehensive collection also covers methods in immunology, animal models, antivirals and vaccine development strategies, as well as biorisk and mitigation measurements for SARS-CoV-2 research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that is vital for success in the lab. Practical and timely, SARS-CoV-2: Methods and Protocols serves as an ideal guide for scientists investigating this prevalent and perilous RNA virus and the novel coronavirus disease that results from it.

Coronavirus Replication and Reverse Genetics

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Publisher : Springer Science & Business Media
ISBN 13 : 3540267654
Total Pages : 261 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Coronavirus Replication and Reverse Genetics by : Luis Enjuanes

Download or read book Coronavirus Replication and Reverse Genetics written by Luis Enjuanes and published by Springer Science & Business Media. This book was released on 2005-10-25 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

Immunobiology of COVID-19

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Publisher : Elsevier
ISBN 13 : 0443132852
Total Pages : 262 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Immunobiology of COVID-19 by :

Download or read book Immunobiology of COVID-19 written by and published by Elsevier. This book was released on 2024-01-17 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive and in-depth exploration of the SARS-CoV-2 virus and its impact on human health. Written by a team of expert contributors, the book covers various aspects of the virus, including its structure, life cycle, and genomic replication. It delves into the epidemiology of COVID-19, comparing it with other related coronaviruses and discussing the concept of herd immunity. The structural biology of SARS-CoV-2 is examined, with a focus on techniques such as electron microscopy and cryo-electron tomography. The book also explores the biology of SARS-CoV-2 variants and their immune evasion strategies. Furthermore, it delves into the pathogenesis of COVID-19, examining its multiorgan manifestations and the long-term effects of the disease. The innate and adaptive immune responses to SARS-CoV-2 are discussed in detail, along with the role of B cells and T cells in the immune response. The volume concludes with a look at future insights and potential developments in the field. Accompanied by illustrative diagrams and visuals, this volume would aid in grasping complex concepts, serving as a valuable resource for researchers, healthcare professionals, and anyone interested in understanding the intricate details of SARS-CoV-2 and its impact on global health. Comprehensive coverage of various aspects of the COVID-19 pandemic, including virus structure, variants, immune responses, disease pathogenesis including its multiorgan manifestations and long COVID Focus on in-depth analysis of innate and adaptive immune responses to SARS-CoV-2, including B cell and T cell responses, discussing the recognition and activation mechanisms, antibody production, immunological memory as well as the role of spike proteins in immunological regulation Richly illustrated with informative diagrams, providing visual aids to enhance understanding of complex concepts and structures related to COVID-19