Molecular Approaches to Tumor Immunotherapy

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Publisher : World Scientific
ISBN 13 : 9789810227937
Total Pages : 348 pages
Book Rating : 4.2/5 (279 download)

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Book Synopsis Molecular Approaches to Tumor Immunotherapy by : Yang Liu

Download or read book Molecular Approaches to Tumor Immunotherapy written by Yang Liu and published by World Scientific. This book was released on 1998 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles in this book are contributed by leading scientists working in the fields of immunology, tumor immunotherapy, and gene therapy. The book identifies the opportunities that modern immunology and molecular biology have provided for tumor therapy. Moreover, it contains critical essays that analyze the progress and obstacles of tumor immunotherapy.

Tumor Immunology and Immunotherapy – Molecular Methods

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Publisher : Academic Press
ISBN 13 : 0128186720
Total Pages : 554 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Tumor Immunology and Immunotherapy – Molecular Methods by :

Download or read book Tumor Immunology and Immunotherapy – Molecular Methods written by and published by Academic Press. This book was released on 2019-11-13 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy – Molecular Methods, Volume 629, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this release include Droplet digital PCR for measuring circulating tumor-derived DNA, Detection and quantification of cytosolic DNA, Methods to detect endogenous dsRNA induction and recognition, Quantification of eIF2alpha phosphorylation during immunogenic cell death, Assessment of annexin A1 release during immunogenic cell death, Luciferase-assisted detection of extracellular ATP in the course of ICD, The P2X7 receptor: structure and function, and much more. Contains the authority of authors who are leaders in their field Provides a comprehensive source on new methods and research in enzymology

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

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Publisher : Academic Press
ISBN 13 : 0128121017
Total Pages : 848 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy by : Herbert B. Newton

Download or read book Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy written by Herbert B. Newton and published by Academic Press. This book was released on 2018-03-28 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors

Molecular Approaches to Cancer Immunotherapy

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (81 download)

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Book Synopsis Molecular Approaches to Cancer Immunotherapy by : Ralph A. Reisfeld

Download or read book Molecular Approaches to Cancer Immunotherapy written by Ralph A. Reisfeld and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel Immunotherapeutic Approaches to the Treatment of Cancer

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Publisher : Springer
ISBN 13 : 3319298275
Total Pages : 285 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Novel Immunotherapeutic Approaches to the Treatment of Cancer by : Paul D. Rennert

Download or read book Novel Immunotherapeutic Approaches to the Treatment of Cancer written by Paul D. Rennert and published by Springer. This book was released on 2016-05-30 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer care is undergoing a radical transformation as novel technologies are directed toward new treatments and personalized medicine. The most dramatic advances in the treatment of cancer have come from therapeutics that augment the immune response to tumors. The immune checkpoint inhibitors are the best-known and most highly advanced examples of Immune Therapeutics targeting tumor cells and include approved antibody drugs directed at the cell surface proteins CTLA4 and PD-1. These are now considered foundational treatments for several solid tumor indications, and that list of indications is growing quickly. More broadly, antibodies have become workhorse molecules across the entire immunotherapy landscape. Antibodies to novel targets modulate the activity of diverse immune cell regulatory proteins. Engineered antibodies can induce tumor cell death or expose tumor cells to poisonous toxins (ADCC and ADC, respectively). Bi-specific antibodies can engage multiple tumor targets simultaneously, or can redirect lymphocytes to attack tumor cells. The antigen-binding domains within antibodies can be spliced onto cell stimulatory domains and transduced into T cells or NK cells, creating remarkable tumor-specific cellular therapeutics (CAR-T, CAR-NK). Beyond antibody-based therapies there are highly diverse and differentiated technology tool kits being applied to immunotherapy. Small molecule drugs are being developed to attack the tumor microenvironment, novel tumor vaccine approaches are showing great promise, patient lymphocytes are being isolated, expanded and reintroduced to patients, gene-editing techniques are becoming widely deployed, and a vast number of new tumor targets, and mutated tumor proteins (neoantigens), are being discovered. The past decade has seen unprecedented success in the treatment of diverse cancers. The authors of this volume have been asked to not only review progress to date, but importantly, to look ahead, and anticipate the evolution of cancer treatment across diverse Immune Therapeutic approaches. Our hypothesis is that the advances we are seeing across the immunotherapy landscape will further evolve and synergize, leading us finally to outright cures for many cancers.

Tumor Immunology and Immunotherapy - Integrated Methods Part B

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Author :
Publisher : Academic Press
ISBN 13 : 0128206675
Total Pages : 404 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Tumor Immunology and Immunotherapy - Integrated Methods Part B by :

Download or read book Tumor Immunology and Immunotherapy - Integrated Methods Part B written by and published by Academic Press. This book was released on 2020-04-01 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quantification methods of Transforming Growth Factor beta (TGF??) activity in the setting of cancer immunotherapy, Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses, Tracking and interrogating tissue-resident and recruited microglia in brain tumors, Metabolomics and lipidomics of the tumor microenvironment, Monitoring abscopal responses to radiation in mice, and much more. Provides an array of authors who are authorities in the field Presents comprehensiveness coverage of the topics Includes a broad level of detail and in-depth coverage

molecular Approaches to Immunology

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Publisher : Elsevier
ISBN 13 : 0323153968
Total Pages : 367 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis molecular Approaches to Immunology by : E.E. Smith

Download or read book molecular Approaches to Immunology written by E.E. Smith and published by Elsevier. This book was released on 2012-12-02 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens. The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume. This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Oncoimmunology

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Publisher : Springer
ISBN 13 : 3319624318
Total Pages : 700 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Oncoimmunology by : Laurence Zitvogel

Download or read book Oncoimmunology written by Laurence Zitvogel and published by Springer. This book was released on 2017-12-13 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.

Tumor Immunology and Immunotherapy - Integrated Methods Part B

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Author :
Publisher : Academic Press
ISBN 13 : 0128206683
Total Pages : 406 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Tumor Immunology and Immunotherapy - Integrated Methods Part B by :

Download or read book Tumor Immunology and Immunotherapy - Integrated Methods Part B written by and published by Academic Press. This book was released on 2020-03-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quantification methods of Transforming Growth Factor beta (TGF?ß) activity in the setting of cancer immunotherapy, Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses, Tracking and interrogating tissue-resident and recruited microglia in brain tumors, Metabolomics and lipidomics of the tumor microenvironment, Monitoring abscopal responses to radiation in mice, and much more. Provides an array of authors who are authorities in the field Presents comprehensiveness coverage of the topics Includes a broad level of detail and in-depth coverage

Systems Biology in Cancer Immunotherapy

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Publisher : Bentham Science Publishers
ISBN 13 : 1681083078
Total Pages : 167 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Systems Biology in Cancer Immunotherapy by : Mahbuba Rahman

Download or read book Systems Biology in Cancer Immunotherapy written by Mahbuba Rahman and published by Bentham Science Publishers. This book was released on 2016-06-07 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decades, systems biology approaches have been applied in different areas of life science research including oncology. Researchers now understand the hallmarks of cancer cells such as abnormal cell growth, inflammation, dysregulated metabolic pathways and drug resistance properties at a molecular level. Systems biology approaches have enabled researchers to investigate cancer immunology by identifying cancer related biomarkers on immune cells, and to study the effect of different therapies in tissue cultures and mouse models. Systems Biology in Cancer Immunotherapy explains the scope of systems biology in understanding the immune response to neoplasms. The book introduces readers to the concepts crucial to cancer immunology before delving into the applied systems biology topics such as the metabolic pathways in cancer cells, the biomolecular roles of signal transduction molecules and their respective biochemical pathways ad cancer immunotherapy. A brief conclusion at the end also provides some information from a clinical and commercial perspective on cancer immunotherapy. This volume is intended as an introductory reference for life science and medical students, researchers and academics interested in the application of systems biology to the immune system in oncology research and chemotherapy practice.

Cancer Immunotherapy

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Publisher : Springer Nature
ISBN 13 : 107163593X
Total Pages : 313 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Cancer Immunotherapy by : Velia Siciliano

Download or read book Cancer Immunotherapy written by Velia Siciliano and published by Springer Nature. This book was released on 2023-12-09 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Tumor Immunology and Immunotherapy - Integrated Methods Part A

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Publisher : Academic Press
ISBN 13 : 0128188758
Total Pages : 344 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Tumor Immunology and Immunotherapy - Integrated Methods Part A by :

Download or read book Tumor Immunology and Immunotherapy - Integrated Methods Part A written by and published by Academic Press. This book was released on 2020-02-28 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry, High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more. Authored by leaders in the field of enzymology Provides a comprehensiveness level of discussion on the field Presents a highly specialized group of topics that delve deep into new updates and future prospects

Immunotherapy of Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1597450111
Total Pages : 517 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Immunotherapy of Cancer by : Mary L. Disis

Download or read book Immunotherapy of Cancer written by Mary L. Disis and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens, adoptive T cell therapy, and adaptive and innate immunity. The challenges in clinical trial design, the need for biomarkers of response-such as novel imaging techniques and immunologic monitoring-and the new advances and directions in cancer immunotherapy are also fully examined.

Single-cell Molecular Characterization for Improving Cancer Immunotherapy

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Publisher : Frontiers Media SA
ISBN 13 : 2889744795
Total Pages : 124 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Single-cell Molecular Characterization for Improving Cancer Immunotherapy by : Qihui Shi

Download or read book Single-cell Molecular Characterization for Improving Cancer Immunotherapy written by Qihui Shi and published by Frontiers Media SA. This book was released on 2022-02-22 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Qihui Shi is the scientific co-founder of JunHealth, a company aiming to developing single-cell sequencing technologies for clinical applications, and received research funding from BeiGene.

Tumor Immunology

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Publisher : CRC Press
ISBN 13 : 0203301854
Total Pages : 224 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Tumor Immunology by : Giorgio Parmiani

Download or read book Tumor Immunology written by Giorgio Parmiani and published by CRC Press. This book was released on 2002-04-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in immunology and molecular biology have resulted in new therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation, and interplay of cells involved in anti-tumor immunity have made the clinical control of some cancers more plausible than previously tho

Cancer Immunotherapy

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Publisher : Academic Press
ISBN 13 : 0128165766
Total Pages : 354 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cancer Immunotherapy by : David B. Teplow

Download or read book Cancer Immunotherapy written by David B. Teplow and published by Academic Press. This book was released on 2019-08-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Immunotherapy, Volume 165 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to different approaches to cancer immunotherapy, with this release focusing on TNFR2 in cancer immunology and immunotherapy, From the Hellstrom paradox towards cancer cure, CAR T-cell treatment of T-cell malignancy , Immunotherapy of pancreatic cancer, Cancer stem cell immunology/immunotherapy, Cytokine release syndrome, Tumor cell-based mechanisms of resistance to immune attack, and Mushroom compounds in cancer immunotherapy. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Cancer Immunotherapy and Biological Cancer Treatments

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789848628
Total Pages : 114 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Cancer Immunotherapy and Biological Cancer Treatments by : Hilal Arnouk

Download or read book Cancer Immunotherapy and Biological Cancer Treatments written by Hilal Arnouk and published by BoD – Books on Demand. This book was released on 2019-11-13 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, biological cancer therapies, including immunotherapy, have moved from the bench to mainstream medical treatments of several types of cancer. The success of these treatments relies on innovative approaches to specifically interfere with molecular targets that are involved in the growth, progression, and spread of malignant cells, or to bypass the tumor evasion of the immune system utilizing the latest advances in cancer vaccine development, formulation, and delivery. This book presents an up-to-date overview of novel cancer biological and immunotherapeutic approaches, including cancer vaccines, mimetic vaccines, monoclonal antibodies, adoptive T-cell transfer, chimeric antigen receptor T- cells, tumor infiltrating lymphocytes, dendritic cells, natural killer cells, immune checkpoint inhibitors, laser ablation, and immune stimulating interstitial laser thermotherapy.