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Modulation Of Igfbp2 Upon Aging Obesity And Insulin Resistance In Mice And Humans
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Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling
Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Muscle and Exercise Physiology by : Jerzy A. Zoladz
Download or read book Muscle and Exercise Physiology written by Jerzy A. Zoladz and published by Academic Press. This book was released on 2018-11-05 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. - Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity - Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes - Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging
Book Synopsis Endocrinology in Clinical Practice, Second Edition by : Philip E. Harris
Download or read book Endocrinology in Clinical Practice, Second Edition written by Philip E. Harris and published by CRC Press. This book was released on 2014-03-24 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology is a complex specialty that spans a wide range of diseases, disorders, and conditions. The field is now moving toward an increasingly personalized approach to patient management, with a greater focus on mechanisms of disease and biomarkers. Written by internationally renowned specialists, the second edition of Endocrinology in Clinical Practice provides a cutting-edge, problem-orientated approach to the management of clinical problems in endocrinology. Highlights of the new edition include: An overview of neuroendocrine disease Strides made by the identification of aryl hydrocarbon receptor–interacting protein mutations in patients with familial isolated pituitary adenomas The diverse roles of IGF-I Changes in diagnostic imaging and the increasing use of positron emission tomography The rapidly increasing incidence of neuroendocrine tumors and their management Hereditary primary hyperparathyroidism and multiple endocrine neoplasia Mechanistic and genomic advances related to disorders of calcium regulation and infertility The endocrinology of aging Protocols for pituitary function testing With complete updates to existing chapters, the second edition also presents new research data, diagnostic techniques, treatment options, and safety concerns related to existing therapies. This edition offers current guidance and scientifically focused information relevant to a range of clinical problems, making it an essential reference for practicing endocrinologists and specialist clinicians.
Book Synopsis Nutrient Regulation of Insulin Secretion by : Peter R. Flatt
Download or read book Nutrient Regulation of Insulin Secretion written by Peter R. Flatt and published by Ashgate Publishing. This book was released on 1992 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mechanisms of release of insulin in response to the body's intake of nutrients has long been one of the central problems of research into diabetes. This book presents the latest findings on the topic from the leading laboratories in the field.
Book Synopsis Obesity and Lipotoxicity by : Ayse Basak Engin
Download or read book Obesity and Lipotoxicity written by Ayse Basak Engin and published by Springer. This book was released on 2017-06-05 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
Book Synopsis Growth Hormone in Adults by : Anders Juul
Download or read book Growth Hormone in Adults written by Anders Juul and published by Cambridge University Press. This book was released on 2000-04-27 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.
Book Synopsis The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease by : Hae-Young Chung
Download or read book The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease written by Hae-Young Chung and published by MDPI. This book was released on 2021-01-29 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer’s disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, “The effects of calorie restriction and intermittent fasting on health and disease”, focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases.
Book Synopsis Anti-diabetes and Anti-obesity Medicinal Plants and Phytochemicals by : Bashar Saad
Download or read book Anti-diabetes and Anti-obesity Medicinal Plants and Phytochemicals written by Bashar Saad and published by Springer. This book was released on 2017-05-11 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a systematic review of traditional herbal medicine and their active compounds, as well as their mechanism of action in the prevention and treatment of diabetes and obesity. The side effects and safety of herbal-derived anti-diabetic and anti-obesity phytochemicals are detailed in depth, and the text has a strong focus on current and future trends in anti-diabetic medicinal plants. This unique and comprehensive text is the only current book on the market focusing exclusively on medicinal plants used to combat obesity and diabetes. An introductory chapter focuses on diabetes and obesity and introduces the major causes and main treatments of this increasing epidemic in modern society. Readers are then introduced to medicinal plants, including details on their therapeutic aspects, plus side effects and safety. Following chapters focus on anti-diabetic and anti-obesity medicinal plants, as well as phytogenic natural products in the treatment of each. The text closes by focusing on present and future trends and challenges in these medicinal plants. Anti-diabetes and Anti-obesity Medicinal Plants and Phytochemicals: Safety, Efficacy, and Action Mechanisms is a much-needed and truly original work, finally presenting in one place all the necessary information on medicinal plants used in conjunction with obesity and diabetes prevention.
Book Synopsis The IGF System by : Charles T. Roberts
Download or read book The IGF System written by Charles T. Roberts and published by Firefly Books. This book was released on 1999-06 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been over 40 years since the original report by Salmon and Daughaday demon strating that the ability of GH to stimulate sulfation of cartilage was mediated by a "sulfation factor. " In the ensuing decades, it has become apparent that this "sulfation factor activity" encompasses a complex system ofligands (IGFs), receptors, and carrier proteins that are, in tum, responsible for a wide array of cellular actions. The IGF system has been demonstrated to be critically involved in both intrauterine and postnatal growth, and to have important implications in cancer biology as well, owing to the ability of the IGFs to function in endocrine, paracrine, and autocrine modes and given the wide distri bution of IGFs in virtually every organ system. The contributions to The /GF System reflect the wide span of interest in the IGF system and its implications for normal and abnormal growth and metabolism. The chapters have been divided into four broad sections: I. Molecular biology of the IGF system; II. Bio logical actions of the IGFs; III. IGF physiology; and IV. Clinical aspects of the IGFs. We have made every effort to highlight the major contemporary themes in IGF biology, but as is inevitable in such a fast-moving field, perspectives will continue to change as new information is accumulated.
Book Synopsis Nutrition and Immunity by : Maryam Mahmoudi
Download or read book Nutrition and Immunity written by Maryam Mahmoudi and published by Springer. This book was released on 2019-07-30 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.
Book Synopsis Obesity and Cancer by : Tobias Pischon
Download or read book Obesity and Cancer written by Tobias Pischon and published by Springer. This book was released on 2016-12-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.
Book Synopsis Insulin-like Growth Factors by : Derek LeRoith
Download or read book Insulin-like Growth Factors written by Derek LeRoith and published by CRC Press. This book was released on 1991-05-28 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, the continued interest in insulin-related growth factors has been documented by a plethora of research programs and publications focused on these growth factors. Both molecular and cellular biological techniques have improved and enabled investigators to study the properties of the growth factors in depth. This volume covers the molecular (genetic) aspects of the growth factors, their binding proteins and receptors, as well as those factors affecting their gene transcription and translation. In addition, aspects of the cellular action of these growth factors through their receptors and how this impacts normal cellular function are discussed. The book will provide valuable information for researchers in physiology, biology, endocrinology, and metabolism.
Book Synopsis Obesity and Cancer by : Shashank Kumar
Download or read book Obesity and Cancer written by Shashank Kumar and published by Springer Nature. This book was released on 2021-07-18 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry.
Book Synopsis The Endocrine System in Sports and Exercise by : William J. Kraemer
Download or read book The Endocrine System in Sports and Exercise written by William J. Kraemer and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.
Book Synopsis The Common Marmoset in Captivity and Biomedical Research by : Robert P. Marini
Download or read book The Common Marmoset in Captivity and Biomedical Research written by Robert P. Marini and published by Academic Press. This book was released on 2018-11-19 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. - Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications - Includes contributions from renowned and international authors and editors - Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series
Book Synopsis Global Action Plan on Physical Activity 2018-2030 by : World Health Organization
Download or read book Global Action Plan on Physical Activity 2018-2030 written by World Health Organization and published by World Health Organization. This book was released on 2019-01-21 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regular physical activity is proven to help prevent and treat noncommunicable diseases (NCDs) such as heart disease stroke diabetes and breast and colon cancer. It also helps to prevent hypertension overweight and obesity and can improve mental health quality of life and well-being. In addition to the multiple health benefits of physical activity societies that are more active can generate additional returns on investment including a reduced use of fossil fuels cleaner air and less congested safer roads. These outcomes are interconnected with achieving the shared goals political priorities and ambition of the Sustainable Development Agenda 2030. The new WHO global action plan to promote physical activity responds to the requests by countries for updated guidance and a framework of effective and feasible policy actions to increase physical activity at all levels. It also responds to requests for global leadership and stronger regional and national coordination and the need for a whole-of-society response to achieve a paradigm shift in both supporting and valuing all people being regularly active according to ability and across the life course. The action plan was developed through a worldwide consultation process involving governments and key stakeholders across multiple sectors including health sports transport urban design civil society academia and the private sector.
Download or read book Insulin and IGFs written by and published by Academic Press. This book was released on 2009-03-10 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.This volume focuses on insulin and IGFs. - Longest running series published by Academic Press - Contributions by leading international authorities