The Link Between Obesity and Cancer

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Publisher : Academic Press
ISBN 13 : 0323909663
Total Pages : 302 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis The Link Between Obesity and Cancer by : Raman Mehrzad

Download or read book The Link Between Obesity and Cancer written by Raman Mehrzad and published by Academic Press. This book was released on 2022-09-22 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Link between Obesity and Cancer provides a comprehensive review on the relationship between obesity and cancer, presenting global perspectives on obesity and cancer incidence that are followed by in-depth discussions on cancers for which we have new evidence of a causal relationship with obesity. Readers will gain fundamental knowledge on which cancer types are related to obesity. In addition, this updated resource provides significant knowledge for clinicians on when to act, along with specific management guidelines for patients, as well as how to understand potential risk factors and how to directly or indirectly minimize these risks. The book also provides never-before-published scientific data for any researcher in the field, identifying molecular mechanisms and links behind the development of malignancy and promoting research in new and effective target pathways in developing therapeutic strategies. Provides essential knowledge on how to understand the link between obesity and cancer and why and how this occurs Presents a significant knowledge base for clinicians on when to act, along with patient management guidelines for patients with obesity and potential risk factors Contains new scientific data and findings for researchers that identify the molecular mechanisms and links behind the development of malignancy

Physical Activity and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3642042317
Total Pages : 389 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Physical Activity and Cancer by : Kerry S. Courneya

Download or read book Physical Activity and Cancer written by Kerry S. Courneya and published by Springer Science & Business Media. This book was released on 2010-11-26 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Weight Control and Physical Activity

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Author :
Publisher : IARC
ISBN 13 : 9789283230069
Total Pages : 346 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Weight Control and Physical Activity by : Harri Vainio

Download or read book Weight Control and Physical Activity written by Harri Vainio and published by IARC. This book was released on 2002 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

Obesity and Gynecology

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Publisher : Elsevier
ISBN 13 : 0128179201
Total Pages : 353 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Obesity and Gynecology by : Tahir A. Mahmood

Download or read book Obesity and Gynecology written by Tahir A. Mahmood and published by Elsevier. This book was released on 2020-06-11 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity and Gynecology, Second Edition, presents updated chapters on a variety of topics, ranging from adolescent obesity, contraception, assisted reproduction and sexual dysfunction, to bariatric surgery and improving semen parameters. The prevalence of obesity in men and women continues to dramatically increase around the world. Obesity presents specific challenges in relation to male and female infertility and general gynecology. Patients who are obese require specific considerations and knowledge. Presents an essential reference on the significant risks of obesity related to contraception, male and female infertility, and general gynecology Builds foundational knowledge, showing how obesity relates to general gynecology, including menstrual disorders, breasts cancer, menopause and sexual dysfunction Assembles critically evaluated chapters that focus on obesity and gynecology to meet the practical needs of gynecologists, endocrinologists and general practitioners

Obesity and Cancer

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Author :
Publisher : Springer
ISBN 13 : 3319425420
Total Pages : 258 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Obesity and Cancer by : Tobias Pischon

Download or read book Obesity and Cancer written by Tobias Pischon and published by Springer. This book was released on 2016-12-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.

Global Health Complications of Obesity

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Publisher : Elsevier
ISBN 13 : 0128197528
Total Pages : 482 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Global Health Complications of Obesity by : Jahangir Moini

Download or read book Global Health Complications of Obesity written by Jahangir Moini and published by Elsevier. This book was released on 2020-04-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Health Complications of Obesity presents a valuable resource for research scientists and clinicians by covering the burden of obesity and related diseases and serving as a starting point for in-depth discussions in academic settings and for obesity-treatment specialists. Obesity is associated with a statistically higher risk of heart disease, hypertension, insulin resistance, type 2 diabetes and many other diseases. This succinct resource focuses on the current data, research and management of obesity. It is essential reading for healthcare professionals, endocrinologists, nutritionists, public health students and medical students. Presents clinical cases, key terms and targeted references Addresses diseases including diabetes, cancer, hypertension, osteoarthritis, fatty liver disease, infertility, renal failure and depression Provides a link to new knowledge that is ideal for both researchers and clinicians

The Role of Obesity in Cancer Survival and Recurrence

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Author :
Publisher : National Academies Press
ISBN 13 : 0309253365
Total Pages : 126 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Role of Obesity in Cancer Survival and Recurrence by : Institute of Medicine

Download or read book The Role of Obesity in Cancer Survival and Recurrence written by Institute of Medicine and published by National Academies Press. This book was released on 2012-06-12 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer.

Obesity as a Common Denominator in Breast Cancer and Cardiovascular Disease

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Author :
Publisher : Cambridge Scholars Publishing
ISBN 13 : 152752180X
Total Pages : 199 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis Obesity as a Common Denominator in Breast Cancer and Cardiovascular Disease by : Katarzyna Rygiel

Download or read book Obesity as a Common Denominator in Breast Cancer and Cardiovascular Disease written by Katarzyna Rygiel and published by Cambridge Scholars Publishing. This book was released on 2018-11-15 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is widely regarded as a shared, modifiable risk factor of both breast cancer (BC) and cardiovascular disease (CVD). Human epidermal growth factor receptor 2 (HER2)-positive BC displays very aggressive behavior, and can be effectively treated with targeted therapies and chemotherapy regimens, though such treatments can induce cardiotoxicity. While the main research efforts are appropriately focused on the management of BC and heart failure (HF), obesity and its metabolic consequences, which are often linked with both these conditions, often remain unaddressed. This book combines a very practical approach, grounded in medical research, to these interconnected medical problems, in order to bridge the gap between current guidelines and clinical practice. It will serve to educate medical team members, such as oncologists, cardiologists, primary care physicians, and nurses, on cardioprotection, and moderate weight reduction. It highlights a need for the balanced integration of modern treatments of BC and HF, with healthy nutrition, regular physical activity, and helpful strategies to cope with chronic stress. In addition, the book represents a supportive resource for BC patients or survivors, who wish to be actively engaged in their long-term therapy journey.

Obesity and Lipotoxicity

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Publisher : Springer
ISBN 13 : 331948382X
Total Pages : 624 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Obesity and Lipotoxicity by : Ayse Basak Engin

Download or read book Obesity and Lipotoxicity written by Ayse Basak Engin and published by Springer. This book was released on 2017-06-05 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.

Energy Balance and Obesity

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Author :
Publisher : IARC Working Group Report
ISBN 13 : 9789283225195
Total Pages : 0 pages
Book Rating : 4.2/5 (251 download)

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Book Synopsis Energy Balance and Obesity by : Isabelle Romieu

Download or read book Energy Balance and Obesity written by Isabelle Romieu and published by IARC Working Group Report. This book was released on 2018-01-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the relationship between energy balance and obesity is essential to develop effective prevention programs and policies. The International Agency for Research on Cancer convened a Working Group of world-leading experts in December 2015 to review the evidence regarding energy balance and obesity, with a focus on low- and middle-income countries, and to consider the following scientific questions: (i) Are the drivers of the obesity epidemic related only to energy excess and/or do specific foods or nutrients play a major role in this epidemic? (ii) What are the factors that modulate these associations? (iii) Which types of data and/or studies will further improve our understanding? This book provides summaries of the evidence from the literature as well as the Working Group's conclusions and recommendations to tackle the global epidemic of obesity.

ABC of Obesity

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Publisher : John Wiley & Sons
ISBN 13 : 1444312707
Total Pages : 64 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis ABC of Obesity by : Naveed Sattar

Download or read book ABC of Obesity written by Naveed Sattar and published by John Wiley & Sons. This book was released on 2009-04-08 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.

Obesity

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Publisher : World Health Organization
ISBN 13 : 9241208945
Total Pages : 267 pages
Book Rating : 4.2/5 (412 download)

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Book Synopsis Obesity by : World Health Organization

Download or read book Obesity written by World Health Organization and published by World Health Organization. This book was released on 2000 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report issues a call for urgent action to combat the growing epidemic of obesity, which now affects developing and industrialized countries alike. Adopting a public health approach, the report responds to both the enormity of health problems associated with obesity and the notorious difficulty of treating this complex, multifactorial disease. With these problems in mind, the report aims to help policy-makers introduce strategies for prevention and management that have the greatest chance of success. The importance of prevention as the most sensible strategy in developing countries, where obesity coexists with undernutrition, is repeatedly emphasized. Recommended lines of action, which reflect the consensus reached by 25 leading authorities, are based on a critical review of current scientific knowledge about the causes of obesity in both individuals and populations. While all causes are considered, major attention is given to behavioural and societal changes that have increased the energy density of diets, overwhelmed sophisticated regulatory systems that control appetite and maintain energy balance, and reduced physical activity. Specific topics discussed range from the importance of fat content in the food supply as a cause of population-wide obesity, through misconceptions about obesity held by both the medical profession and the public, to strategies for dealing with the alarming prevalence of obesity in children. "... the volume is clearly written, and carries a wealth of summary information that is likely to be invaluable for anyone interested in the public health aspects of obesity and fatness, be they students, practitioner or researcher." - Journal of Biosocial Science

The Cancer Code

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Publisher : HarperCollins
ISBN 13 : 0062894021
Total Pages : 368 pages
Book Rating : 4.0/5 (628 download)

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Book Synopsis The Cancer Code by : Dr. Jason Fung

Download or read book The Cancer Code written by Dr. Jason Fung and published by HarperCollins. This book was released on 2020-11-10 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Author of the international bestsellers The Diabetes Code and The Obesity Code Dr. Jason Fung returns with an eye-opening biography of cancer in which he offers a radical new paradigm for understanding cancer—and issues a call to action for reducing risk moving forward. Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline . . . but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease—what it is, how it manifests, and why it is so challenging to treat. In this rousing narrative, Dr. Fung identifies the medical community’s many missteps in cancer research—in particular, its focus on genetics, or what he terms the “seed” of cancer, at the expense of examining the “soil,” or the conditions under which cancer flourishes. Dr. Fung—whose groundbreaking work in the treatment of obesity and diabetes has won him international acclaim—suggests that the primary disease pathway of cancer is caused by the dysregulation of insulin. In fact, obesity and type 2 diabetes significantly increase an individual’s risk of cancer. In this accessible read, Dr. Fung provides a new paradigm for dealing with cancer, with recommendations for what we can do to create a hostile soil for this dangerous seed. One such strategy is intermittent fasting, which reduces blood glucose, lowering insulin levels. Another, eliminating intake of insulin-stimulating foods, such as sugar and refined carbohydrates. For hundreds of years, cancer has been portrayed as a foreign invader we’ve been powerless to stop. By reshaping our view of cancer as an internal uprising of our own healthy cells, we can begin to take back control. The seed of cancer may exist in all of us, but the power to change the soil is in our hands.

Breast Cancer Metastasis and Drug Resistance

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Author :
Publisher : Springer Nature
ISBN 13 : 3030203018
Total Pages : 427 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Breast Cancer Metastasis and Drug Resistance by : Aamir Ahmad

Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Hormonal Contraception and Post-menopausal Hormonal Therapy

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Author :
Publisher : World Health Organization
ISBN 13 :
Total Pages : 692 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hormonal Contraception and Post-menopausal Hormonal Therapy by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Hormonal Contraception and Post-menopausal Hormonal Therapy written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluates evidence for an increased risk of cancer in women using combined oral contraceptives, progestogen-only hormonal contraceptives, post-menopausal estrogen therapy, and post-menopausal estrogen-progestogen therapy. Although the carcinogenicity of these preparations has been extensively investigated, the book stresses the many complex methodological issues that must be considered when interpreting findings and weighing results. Evidence of an association between use of these preparations and positive effects on health, including a reduced risk of some cancers, is also critically assessed. The first and most extensive monograph evaluates evidence of an association between the use of combined oral contraceptives and cancer at nine sites. Concerning breast cancer, the evaluation concludes that, even if the association is causal, the excess risk for breast cancer associated with patterns of use that are typical today is very small. Studies of predominantly high-dose preparations found an increased risk of hepatocellular carcinoma in the absence of hepatitis viruses. Citing these findings, the evaluation concludes that there is sufficient evidence in humans for the carcinogenicity of combined oral contraceptives. The evaluation also found sufficient evidence for the carcinogenicity of some, but not all, combined preparations in animals. Combined oral contraceptives were classified as carcinogenic to humans. The evaluation also cites conclusive evidence that these agents have a protective effect against cancers of the ovary and endometrium. Progestogen-only contraceptives are evaluated in the second monograph, which considers the association with cancer at six sites. The evaluation found no evidence of an increased risk for breast cancer. Although the evaluation found sufficient evidence in animals for the carcinogenicity of medroxyprogesterone acetate, evidence for the carcinogenicity of progestogen-only contraceptives in humans was judged inadequate. Progestogen-only contraceptives were classified as possibly carcinogenic to humans. The third monograph, on post-menopausal estrogen therapy, considers evidence of an association with cancer at eight sites. Findings from a large number of epidemiological studies indicate a small increase in the risk of breast cancer in women who have used these preparations for five years or more. Studies consistently show an association between use of post-menopausal estrogen therapy and an increased risk for endometrial cancer. Data on the association with other cancers were either inconclusive or suggested no effect on risk. The evaluation concludes that post-menopausal estrogen therapy is carcinogenic to humans. The final monograph evaluates the association between the use of post-menopausal estrogen-progestogen therapy and cancer at four sites. The evaluation of limited data on breast cancer found an increased relative risk observed with long-term use. Data were judged insufficient to assess the effects of past use and of different progestogen compounds, doses, and treatment schedules. For endometrial cancer, the evaluation found an increase in risk relative to non-users when the progestogen was added to the cycle for 10 days or fewer. Post-menopausal estrogen-progestogen therapy was classified as possibly carcinogenic to humans. Concerning post-menopausal therapy in general, the book notes that evidence of carcinogenic risks must be placed in perspective of potential benefits. The prevention of osteoporotic fractures is cited as the best-established benefit. Evidence also suggests that estrogen prevents heart disease and may prevent memory loss and dementia.

Dietary Phytochemicals

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Author :
Publisher : Springer Nature
ISBN 13 : 3030729990
Total Pages : 262 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Dietary Phytochemicals by : Chukwuebuka Egbuna

Download or read book Dietary Phytochemicals written by Chukwuebuka Egbuna and published by Springer Nature. This book was released on 2021-08-20 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.

Management of Muscle Invasive Bladder Cancer

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Author :
Publisher : Springer Nature
ISBN 13 : 3030579158
Total Pages : 575 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Management of Muscle Invasive Bladder Cancer by : Sanchia S. Goonewardene

Download or read book Management of Muscle Invasive Bladder Cancer written by Sanchia S. Goonewardene and published by Springer Nature. This book was released on 2021-02-02 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a systematic review of the management and treatment of this disease. The concise and highly structured chapters feature essential background knowledge and commentary on recent advances within each step of a range of patient pathways. Management of Muscle Invasive Bladder Cancer provides a framework for patients’ care based on the research, as well as practically and clinically oriented guidelines. This book is relevant to trainees and practicing urologists and oncologists, in addition to medical professionals involved in the treatment of bladder cancer.