Modulation of Escherichia Coli O157:H7 Mediated Production of Proinflammatory Mediators by Two Species of Lactobacilli in Two Conditionally Immortal Colon Epithelial Cell Lines

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ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Modulation of Escherichia Coli O157:H7 Mediated Production of Proinflammatory Mediators by Two Species of Lactobacilli in Two Conditionally Immortal Colon Epithelial Cell Lines by : Erica M. Block

Download or read book Modulation of Escherichia Coli O157:H7 Mediated Production of Proinflammatory Mediators by Two Species of Lactobacilli in Two Conditionally Immortal Colon Epithelial Cell Lines written by Erica M. Block and published by . This book was released on 2004 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modulation of Intestinal Epithelial Cell-Mediated Defence Responses by Metabolic Products of Lactobacillus Rhamnosus Gg and Escherichia Coli Nissle 1917

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Publisher : Open Dissertation Press
ISBN 13 : 9781361308776
Total Pages : pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis Modulation of Intestinal Epithelial Cell-Mediated Defence Responses by Metabolic Products of Lactobacillus Rhamnosus Gg and Escherichia Coli Nissle 1917 by : Zhijian Chen

Download or read book Modulation of Intestinal Epithelial Cell-Mediated Defence Responses by Metabolic Products of Lactobacillus Rhamnosus Gg and Escherichia Coli Nissle 1917 written by Zhijian Chen and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Modulation of Intestinal Epithelial Cell-mediated Defence Responses by Metabolic Products of Lactobacillus Rhamnosus GG and Escherichia Coli Nissle 1917" by Zhijian, Chen, 陈智健, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Probiotics are defined as live microorganisms that confer beneficial effects to health when administered in a sufficient amount. In previous studies about the beneficial effects of probiotic bacteria to health, particularly in the fields of intestinal mucosa defence responses, specific probiotics, in a strain-dependent manner, show some potential to reinforce the integrity of intestinal epithelium and/or regulate some immune components. However, the mechanisms involved in the interactions between probiotics or bioactive components of probiotics with the intestinal epithelium are still not yet clearly defined or systematically studied. Among all possible routes of modulation by probiotics of intestinal epithelial cell-mediated defence responses, modulations of mucin and trefoil factor expression as well as the cytokine profiles are important components of the innate and adaptive mucosal immune responses of the intestinal epithelial cells and are considered to play important role in the intestinal defence responses against pathogenic bacteria. This thesis examined and characterized the in vitro modulation effects by metabolic products of two commonly studied probiotics bacterial strains, Lactobacillus rhamnosus GG (LGG) and Escherichia coli Nissle 1917 (EcN), on the intestinal epithelial cell-mediated defence responses. It was found that the metabolic products of EcN decreased the transcriptional levels of secretory mucins MUC5AC, MUC5B and MUC2 while LGG metabolic products only down-regulated that of MUC5AC. In partial agreement with the reduction of mucin gene expression levels, intracellular MUC5B and MUC2 mucin expression was reduced by EcN metabolic products and MUC5AC and MUC2 by the metabolic products of LGG. In contrast, the extracellular MUC5AC and MUC2 mucin expression tended to increase upon the effects of both LGG and EcN metabolic products, which might result from accumulative effects of the modulation on extracellular mucin secretion during the time of treatment or the differential responsiveness of cellular mucin gene and protein expression upon stimulation. The expression of trefoil factor 3 in both gene and protein levels upon the effects of EcN metabolic products while those of LGG enhanced the transcriptional but not protein level. As for the modulation of cytokine profiles, LGG metabolic products mainly influence the secretion of anti-inflammatory cytokines such as IL-4, IL-5 and IL-10 in a moderate manner while EcN metabolic products exerted broad pro-inflammatory potential to the intestinal epithelial cells by inducing the secretion of pro-inflammatory cytokines such as IL-8, MCP-1, TGF-α, TNF-α and GM-CSF, which indicated that the metabolic products of LGG and EcN might initiate differential signaling pathway to influence the intestinal epithelial adaptive immune responses. To conclude, the present research provides evidence to substantiate that LGG and EcN display differential modulation mechanisms of the intestinal epithelial cell-mediated defence responses that involve intestinal-cell mediated mucin and trefoil factor secretion as well as pro- and anti-inflammatory cytokine expression. DOI: 10.5353/th_b4979967 Subjects: Intestines - Infections Epithelial cells Intestinal mucosa Lactobacillus Escherichia coli

Colon Epithelial Cells Exposed to Probiotic Bacteria Modify Macrophage Activation and Chemotaxis in Response to a Bacterial Pathogen

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ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Colon Epithelial Cells Exposed to Probiotic Bacteria Modify Macrophage Activation and Chemotaxis in Response to a Bacterial Pathogen by : Amanda Doris Metz

Download or read book Colon Epithelial Cells Exposed to Probiotic Bacteria Modify Macrophage Activation and Chemotaxis in Response to a Bacterial Pathogen written by Amanda Doris Metz and published by . This book was released on 2007 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic Applications of Honey and its Phytochemicals

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Publisher : Springer Nature
ISBN 13 : 9811567999
Total Pages : 404 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Therapeutic Applications of Honey and its Phytochemicals by : Muneeb U. Rehman

Download or read book Therapeutic Applications of Honey and its Phytochemicals written by Muneeb U. Rehman and published by Springer Nature. This book was released on 2020-12-21 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals. It is reported to be beneficial in the treatment of various diseases, such as those affecting the respiratory, cardiovascular, gastrointestinal, and nervous systems, as well as diabetes mellitus and certain types of cancers; however, there is limited literature describing the use of honey in modern medicine. This book provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.

Integrative Cardiology

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Publisher : Springer
ISBN 13 : 331940010X
Total Pages : 273 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Integrative Cardiology by : Massimo Fioranelli

Download or read book Integrative Cardiology written by Massimo Fioranelli and published by Springer. This book was released on 2017-02-10 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a detailed guide to a new integrative approach to the prevention and treatment of various cardiac disorders and risk factors, including coronary artery disease, congestive heart failure, arrhythmias, dyslipidemia, and hypertension. This approach combines various strategies, including metabolic cardiology, low-dose medicine, exercise programs, stress management programs, evaluation for inherited risk factors, and various other healing modalities. Metabolic cardiology focuses on the prevention, management, and treatment of cardiovascular disease at the cellular level through biochemical interventions with nutritional supplements that can promote energy production in the heart. Low-dose medicine, on the other hand, interprets pathological phenomena as an imbalance in intercellular signaling that may be corrected through the administration of low physiological doses of messenger molecules. Therapies outside of mainstream medicine may also be deployed in integrative cardiology, for example acupuncture, herbal medicine, and homeopathy. Integrative Cardiology will be of interest to all practitioners wishing to learn about an approach that incorporates the incredible advances in medication and technology with a focus on nutrition, lifestyle, and mind–body influences.

Sherris Medical Microbiology

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Publisher : McGraw-Hill Europe
ISBN 13 : 9780071638548
Total Pages : 1026 pages
Book Rating : 4.6/5 (385 download)

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Book Synopsis Sherris Medical Microbiology by : Ryan

Download or read book Sherris Medical Microbiology written by Ryan and published by McGraw-Hill Europe. This book was released on 2010-01-01 with total page 1026 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial Cell-to-Cell Communication

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Publisher : Cambridge University Press
ISBN 13 : 9780521846387
Total Pages : 330 pages
Book Rating : 4.8/5 (463 download)

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Book Synopsis Bacterial Cell-to-Cell Communication by : Donald R. Demuth

Download or read book Bacterial Cell-to-Cell Communication written by Donald R. Demuth and published by Cambridge University Press. This book was released on 2006-02-23 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many bacterial diseases are caused by organisms growing together as communities or biofilms. These microorganisms have the capacity to coordinately regulate specific sets of genes by sensing and communicating amongst themselves utilizing a variety of signals. This book examines the mechanisms of quorum sensing and cell-to-cell communication in bacteria and the roles that these processes play in regulating virulence, bacterial interactions with host tissues, and microbial development. Recent studies suggest that microbial cell-to-cell communication plays an important role in the pathogenesis of a variety of disease processes.

Medical Microbiology

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ISBN 13 :
Total Pages : 740 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Microbiology by : Patrick R. Murray

Download or read book Medical Microbiology written by Patrick R. Murray and published by . This book was released on 1998 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clinically relevant introduction focusing on those microbes that cause disease in humans. Following basic principles, basic concepts in the immune response, and general principles of laboratory diagnosis, sections cover bacteriology, virology, mycology and parasitology. Chapters in these sections begin with etiology, then discuss epidemiology, host defenses, identification, diagnosis, prevention, and control. Expanded information on immunology and a new chapter on arthropods are included. Annotation copyrighted by Book News, Inc., Portland, OR

Nutrition in Adolescence

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Publisher : Times Mirror Magazine
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Nutrition in Adolescence by : L. Kathleen Mahan

Download or read book Nutrition in Adolescence written by L. Kathleen Mahan and published by Times Mirror Magazine. This book was released on 1984 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: This text focuses on the nutritional aspects of adolescents and attempts to provide nutrition, dietetics and nursing students with information concerning the characteristics and needs of this group. In addition to a theoretical discussion of nutritional issues in adolescence, this book also contains practical information about providing nutritional care and helping teenagers change their eating habits. Topics include: the physical and psychological characteristics of adolescent growth and development, adolescent life-style and eating behavior, eating disorders, nutrition and adolescent pregnancy, and nurition counseling.

Microstructure and Mechanical Properties of Titanium Alloys

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Publisher : Mdpi AG
ISBN 13 : 9783036522838
Total Pages : 220 pages
Book Rating : 4.5/5 (228 download)

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Book Synopsis Microstructure and Mechanical Properties of Titanium Alloys by : Artur Shugurov

Download or read book Microstructure and Mechanical Properties of Titanium Alloys written by Artur Shugurov and published by Mdpi AG. This book was released on 2021-10-26 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium and its alloys are widely used engineering materials within the aerospace, automotive, energy and chemical industries. Their unique combination of high strength-to-weight ratio, strong resistance to creep, excellent corrosion resistance, and low heat conductivity makes them suitable for a wide range of applications. A large variety of microstructures, including lamellar, martensite, equiaxed globular and bimodal (duplex) microstructures can be obtained in titanium alloys depending on the thermomechanical processing routes. Despite a large amount of work in the field of investigation of microstructure evolution and mechanical properties of titanium alloys, detailed studies of the effect of their microstructure on the mechanical behavior are still necessary because of ever-increasing demands for structural materials to optimize their properties for different applications by varying processing parameters and resulting microstructures. This Special Issue is focused on various aspects of microstructure evolution in titanium alloy samples obtained using traditional and additive technologies and subjected to different processing techniques as well as on the relation between their microstructure and mechanical behavior. The presented original articles cover the areas of preparation and experimental characterization of titanium alloys as well as computer simulation of their mechanical behavior under different loading conditions.

Public Finance in Theory and Practice

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Publisher : Taylor & Francis US
ISBN 13 : 9780415585972
Total Pages : 0 pages
Book Rating : 4.5/5 (859 download)

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Book Synopsis Public Finance in Theory and Practice by : Holley H. Ulbrich

Download or read book Public Finance in Theory and Practice written by Holley H. Ulbrich and published by Taylor & Francis US. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public Finance in Theory and Practice is the most accessible introduction to public finance and public economics available and is any student's first stop for the key tenets of the field including public goods and externalities, taxation, provision for health and education and the analysis of government's role in the economy. With the accession to power in the United States of an administration promising to take a more active role in the economy, now is the time to take stock of how far this process should proceed. Ulbrich's book is the perfect guide to the changing world of public finance.

The MIND Diet

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Publisher : Simon and Schuster
ISBN 13 : 1612436293
Total Pages : 164 pages
Book Rating : 4.6/5 (124 download)

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Book Synopsis The MIND Diet by : Maggie Moon

Download or read book The MIND Diet written by Maggie Moon and published by Simon and Schuster. This book was released on 2016-10-04 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improve your brain health and lower your risk of mental decline by following the breakthrough Mediterranean-DASH Intervention for Neurodegenerative Delay. Enjoying a high quality of life as you get older means taking care of your brain as much as your body. And research suggests that what you eat today will help (or hurt) your cognitive abilities later. The MIND Diet explains the science behind mental fitness in an approachable and understandable way. More importantly, this helpful guide presents an easy-to-follow program for keeping your mind sharp by eating the right foods and avoiding brain-harming ones. Packed with dishes that are not only delicious but also help improve memory, concentration and mental acuity, The MIND Diet’s healthy recipes include: Brussels Sprouts Frittata Sweet Potato Lentil Soup Pistachio Mint Couscous Guacamole-Stuffed Tomatoes Apricot-Glazed Salmon Tango Fish Tacos Banana Chocolate Cookies Roasted Chicken with Fennel

Food, People, and Nutrition

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ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Food, People, and Nutrition by : Eleanor F. Eckstein

Download or read book Food, People, and Nutrition written by Eleanor F. Eckstein and published by . This book was released on 1980 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: People and food interactions determine what and how much is eaten. In order to help people choose a nutritious diet, information on nutrient requirements, and nutrient composition of foods and the effect of variations in nutrient supply or demand are presented. Knowledge from several disciplines in food and nutrition science are combined: whole body and cellular nutrition; life cycle nutrition; food technology; meal management; and the cultural aspects of foods. The effect of nutritional status on cells and specialized organs is discussed. Man's relation to the food environment (food ecology) is described. Other chapters cover dietary assessment, nutritional risk and life expectancy, nutrition for special groups, and the food and nutrition delivery system.

Nutrition and Mental Health

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Publisher : CRC Press
ISBN 13 : 1439863369
Total Pages : 313 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Nutrition and Mental Health by : Ruth Leyse-Wallace

Download or read book Nutrition and Mental Health written by Ruth Leyse-Wallace and published by CRC Press. This book was released on 2013-01-29 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although primary advanced vitamin and mineral deficiencies are rare in the developed world, many common health conditions deplete nutritional status, including sub-optimal dietary intake, frequent alcohol consumption, changes in appetite due to aging, food allergies or sensitivities, special diets, and eating disorders. Covering topics as diverse a

Leaders in Homoeopathic Therapeutics

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Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Leaders in Homoeopathic Therapeutics by : Eugene Beauharnais Nash

Download or read book Leaders in Homoeopathic Therapeutics written by Eugene Beauharnais Nash and published by . This book was released on 1899 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbiology and Immunology

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Publisher :
ISBN 13 : 9780815189831
Total Pages : 400 pages
Book Rating : 4.1/5 (898 download)

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Book Synopsis Microbiology and Immunology by : Ken S. Rosenthal

Download or read book Microbiology and Immunology written by Ken S. Rosenthal and published by . This book was released on 1996-01-01 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is intended to help students prepare for examinations, and contains 100-150 questions, along with another 500 questions on the accompanying diskette. It includes tips on how to arrange study time, and how to take timed multiple-choice exams. The text contains answers to the questions, and the questions on the disk are arranged so as to allow students to pinpoint strengths and areas needing further study.

Greenhouse Technology and Management

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Publisher : CABI
ISBN 13 : 1780641036
Total Pages : 373 pages
Book Rating : 4.7/5 (86 download)

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Book Synopsis Greenhouse Technology and Management by : Nicolás Castilla

Download or read book Greenhouse Technology and Management written by Nicolás Castilla and published by CABI. This book was released on 2013 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translation of the second ed.: Invernaderos de plaastico: tecnologaia y manejo.