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Mobility And Proximity In Biological Membranes
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Book Synopsis Mobility and Proximity in Biological Membranes by : S. Damjanovich
Download or read book Mobility and Proximity in Biological Membranes written by S. Damjanovich and published by CRC Press. This book was released on 2018-01-18 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell surface membranes have long been characterized as two-dimensional fluids whose mobile components are randomized by diffusion in the plane of the membrane bilayer. Recent research has indicated that cell surface membranes are highly organized and ordered and that important functional units of membranes appear as arrays of interacting molecules rather than as single, freely diffusing molecules. Mobility and Proximity in Biological Membranes provides an overview of the results obtained from biophysical methods for probing the organization of cell surface membranes. These results are presented in the context of detailed treatments of the theory and the technical demands of each of the methods. The book describes a versatile and easily applied mode for investigating molecular proximities in plasma membranes in a flow cytometer. Its analysis of lipid fluidity and viscosity of membranes and the rotational mobility of proteins offers intimate insight into the physical chemistry of biological membranes. The electrophysiology of lymphocytes is presented with focus on its importance in different diseases. New techniques are described, and new data, new possibilities, and future trends are presented by world experts. This book's chapters can serve both as guides to the existing literature and as starting points for new experiments and approaches associated with problems in membrane function.
Book Synopsis Mobility and Proximity in Biological Membranes by : S. Damjanovich
Download or read book Mobility and Proximity in Biological Membranes written by S. Damjanovich and published by CRC Press. This book was released on 2018-01-18 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell surface membranes have long been characterized as two-dimensional fluids whose mobile components are randomized by diffusion in the plane of the membrane bilayer. Recent research has indicated that cell surface membranes are highly organized and ordered and that important functional units of membranes appear as arrays of interacting molecules rather than as single, freely diffusing molecules. Mobility and Proximity in Biological Membranes provides an overview of the results obtained from biophysical methods for probing the organization of cell surface membranes. These results are presented in the context of detailed treatments of the theory and the technical demands of each of the methods. The book describes a versatile and easily applied mode for investigating molecular proximities in plasma membranes in a flow cytometer. Its analysis of lipid fluidity and viscosity of membranes and the rotational mobility of proteins offers intimate insight into the physical chemistry of biological membranes. The electrophysiology of lymphocytes is presented with focus on its importance in different diseases. New techniques are described, and new data, new possibilities, and future trends are presented by world experts. This book's chapters can serve both as guides to the existing literature and as starting points for new experiments and approaches associated with problems in membrane function.
Book Synopsis Membrane Permeability: 100 Years Since Ernest Overton by :
Download or read book Membrane Permeability: 100 Years Since Ernest Overton written by and published by Academic Press. This book was released on 1999-05-21 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Provides an historical perspective of Overton's contributions to the theory of narcosis Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion
Book Synopsis Membrane Protein-Cytoskeleton Interactions by :
Download or read book Membrane Protein-Cytoskeleton Interactions written by and published by Academic Press. This book was released on 1996-11-21 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
Book Synopsis Modeling Differential Equations in Biology by : Clifford Henry Taubes
Download or read book Modeling Differential Equations in Biology written by Clifford Henry Taubes and published by Cambridge University Press. This book was released on 2008-01-17 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a very successful one-semester course taught at Harvard, this text teaches students in the life sciences how to use differential equations to help their research. It needs only a semester's background in calculus. Ideas from linear algebra and partial differential equations that are most useful to the life sciences are introduced as needed, and in the context of life science applications, are drawn from real, published papers. It also teaches students how to recognize when differential equations can help focus research. A course taught with this book can replace the standard course in multivariable calculus that is more usually suited to engineers and physicists.
Book Synopsis Membrane Organization and Dynamics by : Amitabha Chattopadhyay
Download or read book Membrane Organization and Dynamics written by Amitabha Chattopadhyay and published by Springer. This book was released on 2017-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes.
Book Synopsis Biochemical Roles of Eukaryotic Cell Surface Macromolecules by : Abhijit Chakrabarti
Download or read book Biochemical Roles of Eukaryotic Cell Surface Macromolecules written by Abhijit Chakrabarti and published by Springer. This book was released on 2014-11-18 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organization · GPCRs and other receptors · biophysical approaches to study membrane interactions · glycoconjugate metabolism · dysregulation · molecular mechanisms involved in cell-cell and cell-matrix interaction · glycans in infectious and neurological diseases · cancer and glycosyltransferases as drug targets.
Book Synopsis Methods in Membrane Lipids by : Alex M. Dopico
Download or read book Methods in Membrane Lipids written by Alex M. Dopico and published by Springer Science & Business Media. This book was released on 2007-08-30 with total page 1265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.
Book Synopsis Fluorescent Proteins by : Kevin F. Sullivan
Download or read book Fluorescent Proteins written by Kevin F. Sullivan and published by Elsevier. This book was released on 2007-12-14 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Fluorescent Proteins presents current applications of autofluorescent proteins in cell and molecular biology authored by researchers from many of the key laboratories in the field. Starting from a current review of the broad palette of fluorescent proteins available, several chapters focus on key autofluorescent protein variants, including spectral variants, photodynamic variants as well as chimeric FP approaches. Molecular applications are addressed in chapters that detail work with single molecules, approaches to generating protein fusions and biosensors as well as analysis of protein-protein interactions in vivo by FRET, fluorescence polarization and fluorescence cross correlation techniques. A number of approaches to in vivo dynamics are presented, including FRAP, photoactivation, and 4-dimensional microscopy. Behavior of spindle components, membrane proteins, mRNA trafficking as well as analysis of cell types in tissues and in development are detailed and provide models for a wide variety of experimental approaches. In addition, several chapters deal directly with the computational issues involved in processing multidimensional image data and using fluorescent imaging to probe cellular behavior with quantitative modeling. This volume brings together the latest perspective and techniques on fluorescent proteins and will be an invaluable reference in a wide range of laboratories.
Book Synopsis Fundamentals of Light Microscopy and Electronic Imaging by : Douglas B. Murphy
Download or read book Fundamentals of Light Microscopy and Electronic Imaging written by Douglas B. Murphy and published by John Wiley & Sons. This book was released on 2012-08-22 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Light Microscopy and Electronic Imaging, Second Edition provides a coherent introduction to the principles and applications of the integrated optical microscope system, covering both theoretical and practical considerations. It expands and updates discussions of multi-spectral imaging, intensified digital cameras, signal colocalization, and uses of objectives, and offers guidance in the selection of microscopes and electronic cameras, as well as appropriate auxiliary optical systems and fluorescent tags. The book is divided into three sections covering optical principles in diffraction and image formation, basic modes of light microscopy, and components of modern electronic imaging systems and image processing operations. Each chapter introduces relevant theory, followed by descriptions of instrument alignment and image interpretation. This revision includes new chapters on live cell imaging, measurement of protein dynamics, deconvolution microscopy, and interference microscopy. PowerPoint slides of the figures as well as other supplementary materials for instructors are available at a companion website: www.wiley.com/go/murphy/lightmicroscopy
Book Synopsis The Living Barrier by : Roy J. Levin
Download or read book The Living Barrier written by Roy J. Levin and published by Butterworth-Heinemann. This book was released on 2014-05-12 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Living Barrier: A Primer on Transfer across Biological Membranes provides information pertinent to the movement of molecules across cell membranes. This book covers a variety of topics, including cell membrane, membrane transfer, water transfer, and movement of charged solutes. Organized into nine chapters, this book begins with an overview of the basic ideas of the cell membrane and reviews the experimental evidence about the structure of the cell membrane. This text then reviews the classical electron microscope pictures of membranes. Other chapters consider the interactions between electrical potentials and the movements of charged substances, which make the membrane transfer of these substances much more complicated than those of neutral molecules. This book discusses as well the aspects of water structure and its influence on membrane permeability. The final chapter deals with the methods by which membranes are synthesized. This book is a valuable resource for biochemists, physiologists, pharmacologists, and botanists.
Book Synopsis Lipid Rafts and Caveolae by : Christopher J. Fielding
Download or read book Lipid Rafts and Caveolae written by Christopher J. Fielding and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
Book Synopsis Fluorescent Methods to Study Biological Membranes by : Yves Mely
Download or read book Fluorescent Methods to Study Biological Membranes written by Yves Mely and published by Springer Science & Business Media. This book was released on 2012-10-10 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous advances have been made in the last few years in our understanding of membrane characteristics and functions. In this context, the present book illustrates some of these major advances by collecting review articles written by highly respected experts. The book is organized in three parts, the first of which deals with membrane probes and model membranes. The second part describes the use of advanced quantitative and high-resolution techniques to explore the properties of biological membranes, illustrating the key progress made regarding membrane organization, dynamics and interactions. The third part is focused on the investigation of membrane proteins using the same techniques, and notably on the membrane receptors that play a central role in signaling pathways and therapeutic strategies. All chapters provide comprehensive information on membranes and their exploration for beginners in the field and advanced researchers alike.
Download or read book Current Topics in Membranes written by and published by . This book was released on 1996 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biophysical Aspects of Transmembrane Signaling by : Sandor Damjanovich
Download or read book Biophysical Aspects of Transmembrane Signaling written by Sandor Damjanovich and published by Springer Science & Business Media. This book was released on 2005-05-20 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transmembrane signaling is one of the most significant cell biological events in the life and death of cells in general and lymphocytes in particular. Until recently biochemists and biophysicists were not accustomed to thinking of these processes from the side of a high number of complex biochemical events and an equally high number of physical changes at molecular and cellular levels at the same time. Both types of researchers were convinced that their findings are the most decisive, having higher importance than the findings of the other scientist population. Both casts were wrong. Life, even at cellular level, has a number of interacting physical and biochemical mechanisms, which finally build up the creation of an "excited" cell that will respond to particular signals from the outer or inner world. This book handles both aspects of the signalling events, and in some cases tries to unify our concepts and help understand the signals that govern the life and death of our cells. Not only the understanding, but also the interference (e.g. medication) may depend on the full knowledge of both sides. These above statements are supported by the application of highly diverse physical and biochemical technologies demonstrated and explained by experts who are pioneers of their particular scientific field.
Book Synopsis Structure and Properties of Cell Membrane Structure and Properties of Cell Membranes by : Benga
Download or read book Structure and Properties of Cell Membrane Structure and Properties of Cell Membranes written by Benga and published by CRC Press. This book was released on 2018-01-18 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in-depth presentations in membrane biology by specialists of international repute. The volumes examine world literature on recent advances in understanding the molecular struc-ture and properties of membranes, the role they play in cellular physiology and cell-cell interactions, and the alterations leading to abnormal cells. Illustrations, tables, and useful appendices com-plement the text. Those professionals actively working in the field of cell membrane investigations as well as biologists, biochemists, biophysicists, physicians, and academicians, will find this work beneficial.
