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Membrane Permeability 100 Years Since Ernest Overton
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Book Synopsis Membrane Permeability: 100 Years Since Ernest Overton by :
Download or read book Membrane Permeability: 100 Years Since Ernest Overton written by and published by Academic Press. This book was released on 1999-05-21 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Provides an historical perspective of Overton's contributions to the theory of narcosis Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion
Book Synopsis Medicinal Chemistry of Drugs Affecting the Nervous System by : M. O. Faruk Khan
Download or read book Medicinal Chemistry of Drugs Affecting the Nervous System written by M. O. Faruk Khan and published by Bentham Science Publishers. This book was released on 2020-09-24 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of the chemical basis of drug action. Medicinal Chemistry of Drugs Affecting the Nervous System is the second volume of the series and it presents 8 chapters focusing on a comprehensive account of drugs affecting the nervous system. The volume informs readers about the medicinal chemistry of relevant drugs, which includes the mechanism of drug action, detail structure activity relationships and metabolism as well as clinical significance of drugs affecting autonomic and central nervous system. Chapters in this volume cover cholinergic drugs, adrenergic drugs, antipsychotics, antidepressants, sedatives, hypnotics, anxiolytics, antiepileptic drugs, anesthetics and antiparkinsonian drugs, respectively. Students and teachers will be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body. The information offered by the book chapters will give readers a strong neuropharmacology knowledge base required for a practicing pharmacist.
Book Synopsis An Introduction to Biological Membranes by : William Stillwell
Download or read book An Introduction to Biological Membranes written by William Stillwell and published by Newnes. This book was released on 2013-04-20 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.
Book Synopsis Advances in Planar Lipid Bilayers and Liposomes by : A. Leitmannova Liu
Download or read book Advances in Planar Lipid Bilayers and Liposomes written by A. Leitmannova Liu and published by Academic Press. This book was released on 2009-10-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Planar Lipid Bilayers and Liposomes, Volume 10, continues to include invited chapters on a broad range of topics, covering the main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group. Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide. * Incorporates contributions from newcomers and established and experienced researchers * Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives * Serves as an indispensable source of information for new scientists
Book Synopsis Encyclopedia of Astrobiology by : Muriel Gargaud
Download or read book Encyclopedia of Astrobiology written by Muriel Gargaud and published by Springer Nature. This book was released on 2023-07-27 with total page 3376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition the Encyclopedia of Astrobiology serves as the key to a common understanding in the extremely interdisciplinary community of astrobiologists. Each new or experienced researcher and graduate student in adjacent fields of astrobiology will appreciate this reference work in the quest to understand the big picture. The carefully selected group of active researchers contributing to this work are aiming to give a comprehensive international perspective on and to accelerate the interdisciplinary advance of astrobiology. The interdisciplinary field of astrobiology constitutes a joint arena where provocative discoveries are coalescing concerning, e.g. the prevalence of exoplanets, the diversity and hardiness of life, and its chances for emergence. Biologists, astrophysicists, (bio)-chemists, geoscientists and space scientists share this exciting mission of revealing the origin and commonality of life in the Universe. With its overview articles and its definitions the Encyclopedia of Astrobiology not only provides a common language and understanding for the members of the different disciplines but also serves for educating a new generation of young astrobiologists who are no longer separated by the jargon of individual scientific disciplines. This new edition offers ~170 new entries. More than half of the existing entries were updated, expanded or supplemented with figures supporting the understanding of the text. Especially in the fields of astrochemistry and terrestrial extremophiles but also in exoplanets and space sciences in general there is a huge body of new results that have been taken into account in this new edition. Because the entries in the Encyclopedia are in alphabetical order without regard for scientific field, this edition includes a section “Astrobiology by Discipline” which lists the entries by scientific field and subfield. This should be particularly helpful to those enquiring about astrobiology, as it illustrates the broad and detailed nature of the field.
Book Synopsis Na Channels from Phyla to Function by :
Download or read book Na Channels from Phyla to Function written by and published by Academic Press. This book was released on 2016-08-29 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Na Channels from Phyla to Function, the latest volume in the Current Topics in Membranes series, is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up-to-date presentation of the current knowledge in the field of Na Channels. Written by leading experts in the field of Na Channels Contains original material, both textual and illustrative, that make it a very relevant reference Presented in a very comprehensive manner Both researchers in the field and general readers will find this book relevant and up-to-date with regard to its information
Book Synopsis Membrane Organization and Dynamics by : Amitabha Chattopadhyay
Download or read book Membrane Organization and Dynamics written by Amitabha Chattopadhyay and published by Springer. This book was released on 2017-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes.
Download or read book Membrane Fusion written by and published by Academic Press. This book was released on 2011-07-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on Membrane Fusion, beginning with fusion and fission of lipid bilayers, with reviews focused on hemifusion and dynamic remodeling of membranes catalyzed by dynamin. Other topics discussed include viral fusion, intracellular fusion, developmental cell fusion, and theoretical modeling.
Download or read book Basement Membranes written by and published by Academic Press. This book was released on 2015-11-24 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basement Membranes focuses on specialized extracellular matrices that provide the scaffolds used and required by cells to organize themselves into tissues and organs. As basement membranes have been shown to be defective in numerous genetic and acquired diseases and to contribute to the microenvironment of both tumor cells and stem cells, this book presents a view of specific basement membrane components and their roles in development and disease, all written and commented on in chapters written by leaders in the basement membrane field. Written by leading experts in the basement membrane field Contains original material, both textual and illustrative, that should become a very relevant reference material Presents material in a very comprehensive manner Ideal for both researchers in the field and general readers who will find relevant and up-to-date information
Book Synopsis Computational Modeling of Membrane Bilayers by : V. Sundararajan
Download or read book Computational Modeling of Membrane Bilayers written by V. Sundararajan and published by Academic Press. This book was released on 2011-08-29 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. Discusses the current state of electrostatics in biomolecular simulations and future directions Includes information on time and length scales in lipid bilayer simulations Includes a chapter on the nature of lipid rafts
Book Synopsis Functional Organization of Vertebrate Plasma Membrane by :
Download or read book Functional Organization of Vertebrate Plasma Membrane written by and published by Elsevier. This book was released on 2013-11-05 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume covers recent breakthroughs in understanding the molecular and cellular basis for patterning vertebrate plasma membranes. A special emphasis is placed on physiological function with chapters covering signaling in the nervous system and heart, vision, and the immune system. consolidates subjects normally dispersed in the literature presents in one volume a subject that has undergone a recent molecular revolution authors are primary contributors and in some cases the founding figures in their fields
Book Synopsis Free Radical Effects on Membranes by :
Download or read book Free Radical Effects on Membranes written by and published by Academic Press. This book was released on 2008-06-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. This volume consist of eleven chapters from experts in the field that encompass free-radical effects on diverse membrane functions, ranging from selective barrier functions, controlling membrane protein function to discussing how the hydrophobic environment within membranes regulate free radical reactivity. The focus is on articles discussing specific examples in which membranes from different cellular compartments (e.g. plasma, ER, mitochondria) and membrane proteins either regulate reactive species formation and reactivity or are specific targets of reactive species leading to alteration in function. * Provides overviews on biomembranes and the impact their physico-chemical properties have on reactive species reactivity * Focuses is on reactive species and control of cell-signaling pathways * Illustrates the concept that different reactive species can modulate function of specific membrane ion channels in different tissues, including sodium channels, chloride channels, sodium-potassium ATPases and calcium channels in both plasma and intracellular organelle membranes
Book Synopsis Dynamic Plasma Membranes: Portals Between Cells and Physiology by :
Download or read book Dynamic Plasma Membranes: Portals Between Cells and Physiology written by and published by Academic Press. This book was released on 2016-01-09 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the recent advances in understanding plasma membrane organization and function beginning with simple systems and extending to specialized membrane domains of vertebrate cells. Written by leading experts in the field Contains original material, both textual and illustrative, that should become a very relevant reference material Presents material in a very comprehensive manner Ideal for both researchers in the field and general readers who will find relevant and up-to-date information
Book Synopsis LIFE - AS A MATTER OF FAT by : Ole G. Mouritsen
Download or read book LIFE - AS A MATTER OF FAT written by Ole G. Mouritsen and published by Springer. This book was released on 2015-10-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book gives a multi-disciplinary perspective on the physics of life and the particular role played by lipids (fats) and the lipid-bilayer component of cell membranes. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nanotechnology and biomedicine are also described. The first edition of the present book was published in 2005 when lipidomics was still very much an emerging science and lipids about to be recognized as being as important for life as proteins, sugars, and genes. This significantly expanded and revised edition takes into account the tremendous amount of knowledge gained over the past decade. In addition, the book now includes more tutorial material on the biochemistry of lipids and the principles of lipid self-assembly. The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences. From the reviews of the first edition: "This is a highly interesting book and a pleasure to read. It represents a new and excellent pedagogical introduction to the field of lipids and the biophysics of biological membranes. I reckon that physicists and chemists as well as biologists will benefit from this approach to the field and Mouritsen shows a deep insight into the physical chemistry of lipids." (Göran Lindblom, Chemistry and Physics of Lipids 2005, vol. 135, page 105-106) "The book takes the reader on an exciting journey through the lipid world, and Mouritsen attracts the attention with a lively style of writing ... . a comprehensive view of the ‘lipid sea’ can be easily achieved, gaining the right perspectives for envisaging future developments in the nascent field of lipidomics." (Carla Ferreri, ChemBioChem, Vol. 6 (8), 2005)
Book Synopsis Membrane Protein Crystallization by :
Download or read book Membrane Protein Crystallization written by and published by Academic Press. This book was released on 2009-05-29 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization. This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers.
Download or read book The Nociceptive Membrane written by and published by Elsevier. This book was released on 2011-09-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membranes are essential cellular organelles. They not only define cells and other organelles, but also are critical in the cell function by selectively regulating the passage of molecules by acting as a matrix for other signaling molecules, and as conduits of information transfer between the external environment and the cell interior. This series was originally added in 1970 and has since provided a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include History of Ion Channels in the Pain Sensory System; Historical Overview; TRPV1, a Polymodal Sensor in the Nociceptor Terminal; Nociceptive Signals to TRPV1 and its Clinical Potential; Gating, Sensitization and Desensitization of TRPV1; TRP Channels as Thermosensors; ASIC Channels; P2X Receptors in Sensory Neurons; Voltage-Gated Sodium Channels and Neuropathic Pain; Voltage-Gated Potassium Channels in Sensory Neurons.
Book Synopsis Basement Membranes: Cell and Molecular Biology by : Nicholas Kefalides
Download or read book Basement Membranes: Cell and Molecular Biology written by Nicholas Kefalides and published by Gulf Professional Publishing. This book was released on 2005-10-24 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basement Membranes: Cell and Molecular Biology brings together the most important research developments of the past 45 years that have enriched our knowledge and contributed to a better understanding of the biochemistry and cell and molecular biology of basement membranes. It describes the studies that shed light on the ultrastructural organization, the biosynthesis of the macromolecular components, their functions in embryonic development and differentiation, and in the mature state. A major portion of the book is devoted to the description of the genes that regulate the expression of the various structural macromolecules. Reviews the early years of research and the discovery of type IV collagen Presents the diversity of basement membrane morphology Discusses gene structure
