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Mixed Effects Models For The Population Approach
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Book Synopsis Mixed Effects Models for the Population Approach by : Marc Lavielle
Download or read book Mixed Effects Models for the Population Approach written by Marc Lavielle and published by CRC Press. This book was released on 2014-07-14 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects ModelsMixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whol
Book Synopsis Mixed Effects Models for Complex Data by : Lang Wu
Download or read book Mixed Effects Models for Complex Data written by Lang Wu and published by CRC Press. This book was released on 2009-11-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.
Book Synopsis Mixed Effects Models for the Population Approach by : Marc Lavielle
Download or read book Mixed Effects Models for the Population Approach written by Marc Lavielle and published by CRC Press. This book was released on 2014-07-14 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects Models Mixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whole population of individuals at the same time. Easy-to-Use Techniques and Tools for Real-World Data Modeling The book first shows how the framework allows model representation for different data types, including continuous, categorical, count, and time-to-event data. This leads to the use of generic methods, such as the stochastic approximation of the EM algorithm (SAEM), for modeling these diverse data types. The book also covers other essential methods, including Markov chain Monte Carlo (MCMC) and importance sampling techniques. The author uses publicly available software tools to illustrate modeling tasks. Methods are implemented in Monolix, and models are visually explored using Mlxplore and simulated using Simulx. Careful Balance of Mathematical Representation and Practical Implementation This book takes readers through the whole modeling process, from defining/creating a parametric model to performing tasks on the model using various mathematical methods. Statisticians and mathematicians will appreciate the rigorous representation of the models and theoretical properties of the methods while modelers will welcome the practical capabilities of the tools. The book is also useful for training and teaching in any field where population modeling occurs.
Book Synopsis Linear Mixed-Effects Models Using R by : Andrzej Gałecki
Download or read book Linear Mixed-Effects Models Using R written by Andrzej Gałecki and published by Springer Science & Business Media. This book was released on 2013-02-05 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Linear mixed-effects models (LMMs) are an important class of statistical models that can be used to analyze correlated data. Such data are encountered in a variety of fields including biostatistics, public health, psychometrics, educational measurement, and sociology. This book aims to support a wide range of uses for the models by applied researchers in those and other fields by providing state-of-the-art descriptions of the implementation of LMMs in R. To help readers to get familiar with the features of the models and the details of carrying them out in R, the book includes a review of the most important theoretical concepts of the models. The presentation connects theory, software and applications. It is built up incrementally, starting with a summary of the concepts underlying simpler classes of linear models like the classical regression model, and carrying them forward to LMMs. A similar step-by-step approach is used to describe the R tools for LMMs. All the classes of linear models presented in the book are illustrated using real-life data. The book also introduces several novel R tools for LMMs, including new class of variance-covariance structure for random-effects, methods for influence diagnostics and for power calculations. They are included into an R package that should assist the readers in applying these and other methods presented in this text.
Book Synopsis Mixed-Effects Models in S and S-PLUS by : José C. Pinheiro
Download or read book Mixed-Effects Models in S and S-PLUS written by José C. Pinheiro and published by Springer Science & Business Media. This book was released on 2009-04-15 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: R, linear models, random, fixed, data, analysis, fit.
Book Synopsis Linear Mixed Models by : Brady T. West
Download or read book Linear Mixed Models written by Brady T. West and published by CRC Press. This book was released on 2006-11-22 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simplifying the often confusing array of software programs for fitting linear mixed models (LMMs), Linear Mixed Models: A Practical Guide Using Statistical Software provides a basic introduction to primary concepts, notation, software implementation, model interpretation, and visualization of clustered and longitudinal data. This easy-to-nav
Download or read book Mixed Models written by Eugene Demidenko and published by John Wiley & Sons. This book was released on 2013-08-05 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition “This book will serve to greatly complement the growing number of texts dealing with mixed models, and I highly recommend including it in one’s personal library.” —Journal of the American Statistical Association Mixed modeling is a crucial area of statistics, enabling the analysis of clustered and longitudinal data. Mixed Models: Theory and Applications with R, Second Edition fills a gap in existing literature between mathematical and applied statistical books by presenting a powerful examination of mixed model theory and application with special attention given to the implementation in R. The new edition provides in-depth mathematical coverage of mixed models’ statistical properties and numerical algorithms, as well as nontraditional applications, such as regrowth curves, shapes, and images. The book features the latest topics in statistics including modeling of complex clustered or longitudinal data, modeling data with multiple sources of variation, modeling biological variety and heterogeneity, Healthy Akaike Information Criterion (HAIC), parameter multidimensionality, and statistics of image processing. Mixed Models: Theory and Applications with R, Second Edition features unique applications of mixed model methodology, as well as: Comprehensive theoretical discussions illustrated by examples and figures Over 300 exercises, end-of-section problems, updated data sets, and R subroutines Problems and extended projects requiring simulations in R intended to reinforce material Summaries of major results and general points of discussion at the end of each chapter Open problems in mixed modeling methodology, which can be used as the basis for research or PhD dissertations Ideal for graduate-level courses in mixed statistical modeling, the book is also an excellent reference for professionals in a range of fields, including cancer research, computer science, and engineering.
Book Synopsis Methods and Applications of Longitudinal Data Analysis by : Xian Liu
Download or read book Methods and Applications of Longitudinal Data Analysis written by Xian Liu and published by Elsevier. This book was released on 2015-09-01 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods and Applications of Longitudinal Data Analysis describes methods for the analysis of longitudinal data in the medical, biological and behavioral sciences. It introduces basic concepts and functions including a variety of regression models, and their practical applications across many areas of research. Statistical procedures featured within the text include: - descriptive methods for delineating trends over time - linear mixed regression models with both fixed and random effects - covariance pattern models on correlated errors - generalized estimating equations - nonlinear regression models for categorical repeated measurements - techniques for analyzing longitudinal data with non-ignorable missing observations Emphasis is given to applications of these methods, using substantial empirical illustrations, designed to help users of statistics better analyze and understand longitudinal data. Methods and Applications of Longitudinal Data Analysis equips both graduate students and professionals to confidently apply longitudinal data analysis to their particular discipline. It also provides a valuable reference source for applied statisticians, demographers and other quantitative methodologists. - From novice to professional: this book starts with the introduction of basic models and ends with the description of some of the most advanced models in longitudinal data analysis - Enables students to select the correct statistical methods to apply to their longitudinal data and avoid the pitfalls associated with incorrect selection - Identifies the limitations of classical repeated measures models and describes newly developed techniques, along with real-world examples.
Book Synopsis A Life Course Perspective on Health Trajectories and Transitions by : Claudine Burton-Jeangros
Download or read book A Life Course Perspective on Health Trajectories and Transitions written by Claudine Burton-Jeangros and published by Springer. This book was released on 2015-08-11 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book examines health trajectories and health transitions at different stages of the life course, including childhood, adulthood and later life. It provides findings that assess the role of biological and social transitions on health status over time. The essays examine a wide range of health issues, including the consequences of military service on body mass index, childhood obesity and cardiovascular health, socio-economic inequalities in preventive health care use, depression and anxiety during the child rearing period, health trajectories and transitions in people with cystic fibrosis and oral health over the life course. The book addresses theoretical, empirical and methodological issues as well as examines different national contexts, which help to identify factors of vulnerability and potential resources that support resilience available for specific groups and/or populations. Health reflects the ability of individuals to adapt to their social environment. This book analyzes health as a dynamic experience. It examines how different aspects of individual health unfold over time as a result of aging but also in relation to changing socioeconomic conditions. It also offers readers potential insights into public policies that affect the health status of a population.
Book Synopsis Mixed Effects Models and Extensions in Ecology with R by : Alain Zuur
Download or read book Mixed Effects Models and Extensions in Ecology with R written by Alain Zuur and published by Springer Science & Business Media. This book was released on 2009-03-05 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses advanced statistical methods that can be used to analyse ecological data. Most environmental collected data are measured repeatedly over time, or space and this requires the use of GLMM or GAMM methods. The book starts by revising regression, additive modelling, GAM and GLM, and then discusses dealing with spatial or temporal dependencies and nested data.
Book Synopsis Doing Meta-Analysis with R by : Mathias Harrer
Download or read book Doing Meta-Analysis with R written by Mathias Harrer and published by CRC Press. This book was released on 2021-09-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book
Book Synopsis Longitudinal Data Analysis by : Garrett Fitzmaurice
Download or read book Longitudinal Data Analysis written by Garrett Fitzmaurice and published by CRC Press. This book was released on 2008-08-11 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory
Book Synopsis Introduction to Mixed Modelling by : N. W. Galwey
Download or read book Introduction to Mixed Modelling written by N. W. Galwey and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mixed modelling is one of the most promising and exciting areas ofstatistical analysis, enabling more powerful interpretation of datathrough the recognition of random effects. However, many perceivemixed modelling as an intimidating and specialized technique. Thisbook introduces mixed modelling analysis in a simple andstraightforward way, allowing the reader to apply the techniqueconfidently in a wide range of situations. Introduction to Mixed Modelling shows that mixedmodelling is a natural extension of the more familiar statisticalmethods of regression analysis and analysis of variance. In doingso, it provides the ideal introduction to this importantstatistical technique for those engaged in the statistical analysisof data. This essential book: Demonstrates the power of mixed modelling in a wide range ofdisciplines, including industrial research, social sciences,genetics, clinical research, ecology and agriculturalresearch. Illustrates how the capabilities of regression analysis can becombined with those of ANOVA by the specification of a mixedmodel. Introduces the criterion of Restricted Maximum Likelihood(REML) for the fitting of a mixed model to data. Presents the application of mixed model analysis to a widerange of situations and explains how to obtain and interpret BestLinear Unbiased Predictors (BLUPs). Features a supplementary website containing solutions toexercises, further examples, and links to the computer softwaresystems GenStat and R. This book provides a comprehensive introduction to mixedmodelling, ideal for final year undergraduate students,postgraduate students and professional researchers alike. Readerswill come from a wide range of scientific disciplines includingstatistics, biology, bioinformatics, medicine, agriculture,engineering, economics, and social sciences.
Book Synopsis Hierarchical Linear Modeling by : G. David Garson
Download or read book Hierarchical Linear Modeling written by G. David Garson and published by SAGE. This book was released on 2013 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a brief, easy-to-read guide to implementing hierarchical linear modeling using three leading software platforms, followed by a set of original how-to applications articles following a standardard instructional format. The "guide" portion consists of five chapters by the editor, providing an overview of HLM, discussion of methodological assumptions, and parallel worked model examples in SPSS, SAS, and HLM software. The "applications" portion consists of ten contributions in which authors provide step by step presentations of how HLM is implemented and reported for introductory to intermediate applications.
Book Synopsis Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models by : Joel S. Owen
Download or read book Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models written by Joel S. Owen and published by John Wiley & Sons. This book was released on 2014-07-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. • Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects • Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment • Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control • Has datasets, programming code, and practice exercises with solutions, available on a supplementary website
Book Synopsis Optimal Design for Nonlinear Response Models by : Valerii V. Fedorov
Download or read book Optimal Design for Nonlinear Response Models written by Valerii V. Fedorov and published by CRC Press. This book was released on 2013-07-15 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors' many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of
Book Synopsis Hierarchical Linear Models by : Stephen W. Raudenbush
Download or read book Hierarchical Linear Models written by Stephen W. Raudenbush and published by SAGE. This book was released on 2002 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition of a text in which Raudenbush (U. of Michigan) and Bryk (sociology, U. of Chicago) provide examples, explanations, and illustrations of the theory and use of hierarchical linear models (HLM). New material in Part I (Logic) includes information on multivariate growth models and other topics.
