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Microfabricated Components For An Integrated Microfluidic Electroanalysis System
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Book Synopsis Microfabricated Components for an Integrated Microfluidic Electroanalysis System by : Ponnambalam Selvaganapathy
Download or read book Microfabricated Components for an Integrated Microfluidic Electroanalysis System written by Ponnambalam Selvaganapathy and published by . This book was released on 2002 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microfluidic Biochemical Analysis System with Electro-osmotic Pump and Thermally Responsive Polymer Valve by : Senol Mutlu
Download or read book Microfluidic Biochemical Analysis System with Electro-osmotic Pump and Thermally Responsive Polymer Valve written by Senol Mutlu and published by . This book was released on 2005 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microfabrication Techniques for Scalable Manufacturing of Integrated Microfluidic Devices by : Jonathan Pegan
Download or read book Microfabrication Techniques for Scalable Manufacturing of Integrated Microfluidic Devices written by Jonathan Pegan and published by . This book was released on 2013 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micromachining techniques have enabled the rapid expansion of small-scale medical devices. However, as these techniques were originally developed for the integrated circuit industry, many of the processes and materials are ill suited for use in biological systems. Importantly, as current biomedical devices are larger then integrated circuits, scalability of manufacturing becomes a major challenge. There is a great need to discover new techniques and materials in the fabrication of biomedical microdevices that are inexpensive and can be easily scaled up for commercial production. Presented in this work are microfabrication techniques adapted for use with shape-memory polymers. These shape-memory polymers are less costly and more biocompatible then standard biomedical microdevice processes and materials. Notably, as these films are flexible, they are compatible with roll-to-roll manufacturing. These films are used to create a number of biomedical microdevices inexpensively with scalable fabrication processes to aid in the translation of biomedical microtechnology for point-of-care diagnostics.
Book Synopsis An Integrated Microfluidic Platform for Chemical and Biological Sensing Employing Polymer-coated Piezoelectric Microcantilevers by : Masoud Khabiry
Download or read book An Integrated Microfluidic Platform for Chemical and Biological Sensing Employing Polymer-coated Piezoelectric Microcantilevers written by Masoud Khabiry and published by . This book was released on 2015 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic integrated systems offer several advantages compared to macroscopic techniques. The ability to handle small sample volumes, portability, and the low cost of the devices are the most significant of these advantages. Microfluidic systems have substantially advanced the landscape of chemical and biological research. Microfluidic platforms hold great promise in manipulation and examination of single cells, single molecules, sensor integration, chemical synthesis, biochemical assays, bioanalysis, and high-throughput screening. In addition, microfluidic systems have great potential for integration of Micro/Nano electromechanical systems (MEMS/NEMS) and microcantilever-based sensors. In this work, an integrated microfluidic system with shear-protective regions that enables cell and particle immobilization, sensor integration, and nanoparticle synthesis is presented. Thus, a novel and simple microfluidic device for capturing small volume of cells by using sidewall microgroove containing channels and microposts is developed. The developed microfluidic system enabled the control of fluid flow and shear stress profiles. Furthermore, the shear stress variation and cell positioning in the sidewall microgrooves were investigated. Moreover, the histograms of cell locations in the microgrooves were provided and the most probable destination of the cells was presented. In the microfluidic device, further investigation on extracting cell information from image data was carried out. Hence, a cell segmentation technique was developed for cell counting and extracting the cell information from the microfluidic device. This platform also has the capability of integration of polymer coated piezoelectric microcantilevers which can be functionalized for analyte detection. Piezoelectric microcantilever-based sensors provide less complex system, eliminate the need for external optics and optical alignments, operate under larger gap distances, consume less power and generate less heat. Furthermore, piezoelectric microcantilever-based sensors can operate in the self-sensing manner where a piezoelectric layer embedded in the structure of the microcantilevers can be used for both sensing and actuating purposes. Moreover, an excellent way of enhancing and broadening the applicability and functionality of piezoelectric microcantilever-based sensors is to coat them with a layer of sensitive polymer. The data obtained from analyte detection by polymer coated piezoelectric microcantilever was presented. In addition, through a combined mathematical modeling the experimental findings were rationalized. Integration of microfluidic platform containing polymer coated piezoelectric microcantilever was presented. Utilization of three-dimensional (3D) printing method for developing of the microfluidic component of integrated system was discussed. Alternative physical set-up of the integrated microfluidic platform containing microcantilever array was presented. Microfluidic devices are also able to rapidly mix reagents, and provide homogenous reaction environments. These features make them an ideal platform for nanoparticle synthesis. In this work, capability of nanoparticle synthesis by our microfluidic platform was also presented. In particular, flow focusing microfluidic technique for continuous synthesis of nanoparticles was examined. There are some improvements that can be pursued for further investigation on the presented integrated platform such as using different shapes and angles of sidewall microgrooves. Overall, it is possible to use this simple and adaptable platform for a sensitive detection of a wide range of analytes.
Book Synopsis Modular Integration of Microfluidic Systems on Printed Circuit Boards by : Sarkis Babikian
Download or read book Modular Integration of Microfluidic Systems on Printed Circuit Boards written by Sarkis Babikian and published by . This book was released on 2011 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic technology has the potential to revolutionize practices in analytical chemistry, biology and point of care applications, through the introduction of small, automated and portable microfluidic systems that can replicate fluidic assays using reduced amount of samples. However, this cannot be realized without integrating active components and functionalities into these devices, which has presented a significant challenge for microfluidic fabrication. In this work, a modular integration method is proposed to promote standardized and low cost fabrication of microfluidic systems on printed circuit boards (PCB) and allow the integration of standard electronic components into these systems. Industrial polyurethane is introduced and characterized to fabricate microfluidics on PCBs. A novel surface mount microfluidic thermal component is reported and successfully integrated into a microfluidic chip to perform on-chip cell lysis and isotachophoretic separation of analytes.
Book Synopsis Microfluidic Circuitry via Additive Manufacturing by : Casey Carter Glick
Download or read book Microfluidic Circuitry via Additive Manufacturing written by Casey Carter Glick and published by . This book was released on 2005 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics, the science and engineering of fluid at small scales, affords numerous benefits for applications in chemistry and biology, including rapid reaction rates, reaction uniformity and precision, and reagent minimization but the technology remains limited by the availability of appropriate control mechanisms and related microfluidic components. Microfluidic devices have traditionally been fabricated using soft-lithography, which is time-consuming, costly, and reliant on extensive facilities. Over the past decade, research has shifted towards developing alternate methods such as additive manufacturing (widely known as three-dimensional (3D) printing) to fabricate microfluidic structures. This dissertation has developed three methods for resolving the fabrication and control problems of microfluidics using a combination of standard microfluidic/MEMS techniques with newer 3D printing techniques: optofluidic lithographic microfluidic circuitry, 3D-printed transfer molding, and fully-3D-printed fluidic circuitry. The basic theory of microfluidic control systems, including the hydraulic analogy and fluidic circuitry, the low Reynolds number approximation to the Navier-Stokes equations, and neglectable terms in microfluidic models are first investigated. Optofluidic lithography, where photocurable liquids are selectively solidified under UV exposure, is utilized as a means of fabricating moving microfluidic structures within a microchannel. Several variants of microfluidic control mechanisms are demonstrated, including current sources (for regulation of fluid flow-rates to $29.2 \pm 0.8$ \si{\micro\liter/min} for pressures from $5-10$ kPa), and microfluidic gain valves (for controlling a high-pressure channel with a low-pressure one to achieve a dynamic gain of $6.30 \pm 0.23$). A hybrid manufacturing process, where 3D printed polymer molds are used to make multi-layer PDMS constructions by employing unique molding, bonding, alignment, and rapid assembly processes. Specifically, a novel single-layer, two-sided molding method is developed to realize two channels levels, non-planar membranes/valves, vertical interconnects (vias) between channel levels, and built-in inlet/outlet ports for fast linkages to external fluidic systems. As a demonstration, a single-layer membrane micro-valve is constructed, dramatically reducing the number of fabrication steps. Additionally, multilayer structures are fabricated through an intra-layer bonding procedure which uses custom 3D printed stamps to selectively apply uncured liquid PDMS adhesive only to bonding interfaces without clogging fluidic channels. Using built-in alignment marks to accurately position both stamps and individual layers, this technique is demonstrated by rapidly assembling a six-layer microfluidic device. By using the multi-jet-based additive manufacturing, fully-3D-printed microfluidic circuitry components are demonstrated, including fluidic resistors, capacitors, diodes (for a diodicity of $80.6 \pm 1.8$), and transistors (for a dynamic pressure gain of $3.01 \pm 0.78$) through the combination of experimental, simulation, and analytical methods, which are integrated complex microfluidic circuits, such as half- and full-wave microfluidic rectifiers. The hydraulic analogy circuitry exhibits similar transfer functions to its electronic counterparts, but ultimately behaves more similarly to vacuum triodes than to actual transistors. When combined with fully-realized microfluidic IF-gate and CMOS-analog components, this research may allow for fabrication of analog microfluidic operational-amplifiers, which could allow for fully-analog control of microfluidic systems using high-gain amplification of small pressure signals, and the CAD-based nature of the design process makes it simple for researchers to readily combine multiple microfluidic components into larger integrated microfluidic circuit networks.
Download or read book Microfluidics written by Yu Song and published by John Wiley & Sons. This book was released on 2018-05-07 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2003 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nanoelectrochemistry by : Michael V. Mirkin
Download or read book Nanoelectrochemistry written by Michael V. Mirkin and published by CRC Press. This book was released on 2015-03-27 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale electrochemistry has revolutionized electrochemical research and technologies and has impacted other fields, including nanotechnology and nanoscience, biology, and materials chemistry. This book examines well-established concepts and principles and provides an updated overview of the field and its applications. The first two chapters contain theoretical background, specifically, theories of electron transfer, transport, and double-layer processes at nanoscale electrochemical interfaces. The next chapters examine the electrochemical studies of nanomaterials and nanosystems, as well as the applications of nanoelectrochemical techniques. Each chapter can be read independently, providing readers with a compact, up-to-date review of th
Book Synopsis 3D Printed Microfluidic Devices by : Savas Tasoglu
Download or read book 3D Printed Microfluidic Devices written by Savas Tasoglu and published by MDPI. This book was released on 2019-01-10 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines
Author :Society of Photo-optical Instrumentation Engineers Publisher :SPIE-International Society for Optical Engineering ISBN 13 : Total Pages :182 pages Book Rating :4.F/5 ( download)
Book Synopsis Micro- and Nanofabricated Structures and Devices for Biomedical Environmental Applications II by : Society of Photo-optical Instrumentation Engineers
Download or read book Micro- and Nanofabricated Structures and Devices for Biomedical Environmental Applications II written by Society of Photo-optical Instrumentation Engineers and published by SPIE-International Society for Optical Engineering. This book was released on 1999 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Agricultural and Food Electroanalysis by : Alberto Escarpa
Download or read book Agricultural and Food Electroanalysis written by Alberto Escarpa and published by John Wiley & Sons. This book was released on 2015-07-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Agricultural and Food Electroanalysis offers a comprehensive rationale of electroanalysis, revealing its enormous potential in agricultural food analysis. A unique approach is used which fills a gap in the literature by bringing in applications to everyday problems. This timely text presents in-depth descriptions about different electrochemical techniques following their basic principles, instrumentation and main applications. Such techniques offer invaluable features such as inherent miniaturization, high sensitivity and selectivity, low cost, independence of sample turbidity, high compatibility with modern technologies such as microchips and biosensors, and the use of exciting nanomaterials such as nanoparticles, nanotubes and nanowires. Due to the advantages that modern electroanalytical techniques bring to food analysis, and the huge importance and emphasis given today to food quality and safety, this comprehensive work will be an essential read for professionals and researchers working in analytical laboratories and development departments, and a valuable guide for students studying for careers in food science, technology and chemistry.
Book Synopsis Challenges in Green Analytical Chemistry by : Miguel de la Guardia
Download or read book Challenges in Green Analytical Chemistry written by Miguel de la Guardia and published by Royal Society of Chemistry. This book was released on 2011 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at managers of analytical laboratories but will also interest teachers of analytical chemistry and green public policy makers this is a must for anyone working in or affiliated with Green Chemistry.
Book Synopsis Handbook of Green Analytical Chemistry by : Miguel de la Guardia
Download or read book Handbook of Green Analytical Chemistry written by Miguel de la Guardia and published by John Wiley & Sons. This book was released on 2012-02-23 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging field of green analytical chemistry is concerned with the development of analytical procedures that minimize consumption of hazardous reagents and solvents, and maximize safety for operators and the environment. In recent years there have been significant developments in methodological and technological tools to prevent and reduce the deleterious effects of analytical activities; key strategies include recycling, replacement, reduction and detoxification of reagents and solvents. The Handbook of Green Analytical Chemistry provides a comprehensive overview of the present state and recent developments in green chemical analysis. A series of detailed chapters, written by international specialists in the field, discuss the fundamental principles of green analytical chemistry and present a catalogue of tools for developing environmentally friendly analytical techniques. Topics covered include: Concepts: Fundamental principles, education, laboratory experiments and publication in green analytical chemistry. The Analytical Process: Green sampling techniques and sample preparation, direct analysis of samples, green methods for capillary electrophoresis, chromatography, atomic spectroscopy, solid phase molecular spectroscopy, derivative molecular spectroscopy and electroanalytical methods. Strategies: Energy saving, automation, miniaturization and photocatalytic treatment of laboratory wastes. Fields of Application: Green bioanalytical chemistry, biodiagnostics, environmental analysis and industrial analysis. This advanced handbook is a practical resource for experienced analytical chemists who are interested in implementing green approaches in their work.
Book Synopsis Micro Total Analysis Systems by : Albert Berg
Download or read book Micro Total Analysis Systems written by Albert Berg and published by Springer Science & Business Media. This book was released on 1995 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of silicon-based microsystems for chemical analysis is one of the most promising concepts in the recent developments in micro system technology (MST). It is expected that chemical sensors will be increasingly integrated in so-called miniaturized total analysis systems (muTAS), a concept first presented by Ciba-Geigy. In such systems, all steps in a chemical determination, from sampling to detection and data treatment, are integrated in one miniature instrument. muTAS offer a variety of advantages over conventional analysis systems such as improved analytical performance, reduced reagent and power consumption, small size, possibility of new and more complicated functions, higher reliability and lower fabrication costs. Application of muTAS may be found in fields like process industry, environmental monitoring, medical diagnostics, aeronautics, automotive industry, etc.
Book Synopsis Applications of Nanomaterials in Sensors and Diagnostics by : Adisorn Tuantranont
Download or read book Applications of Nanomaterials in Sensors and Diagnostics written by Adisorn Tuantranont and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent progress in the synthesis of nanomaterials and our fundamental understanding of their properties has led to significant advances in nanomaterial-based gas, chemical and biological sensors. Leading experts around the world highlight the latest findings on a wide range of nanomaterials including nanoparticles, quantum dots, carbon nanotubes, molecularly imprinted nanostructures or plastibodies, nanometals, DNA-based structures, smart nanomaterials, nanoprobes, magnetic nanomaterials, organic molecules like phthalocyanines and porphyrins, and the most amazing novel nanomaterial, called graphene. Various sensing techniques such as nanoscaled electrochemical detection, functional nanomaterial-amplified optical assays, colorimetry, fluorescence and electrochemiluminescence, as well as biomedical diagnosis applications, e.g. for cancer and bone disease, are thoroughly reviewed and explained in detail. This volume will provide an invaluable source of information for scientists working in the field of nanomaterial-based technology as well as for advanced students in analytical chemistry, biochemistry, electrochemistry, material science, micro- and nanotechnology.
Book Synopsis CRC Concise Encyclopedia of Nanotechnology by : Boris Ildusovich Kharisov
Download or read book CRC Concise Encyclopedia of Nanotechnology written by Boris Ildusovich Kharisov and published by CRC Press. This book was released on 2016-01-06 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CRC Concise Encyclopedia of Nanotechnology sets the standard against which all other references of this nature are measured. As such, it is a major resource for both skilled professionals and novices to nanotechnology.The book examines the design, application, and utilization of devices, techniques, and technologies critical to research at the
