Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications

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Publisher : Elsevier
ISBN 13 : 044318867X
Total Pages : 490 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications by : Huseyin Tombuloglu

Download or read book Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications written by Huseyin Tombuloglu and published by Elsevier. This book was released on 2024-08-01 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the field of genomics has progressed, our understanding of microbiology has also developed. With the advent of next-generation sequencing methods and advancements in instrumental resolution, complex transcriptome, proteome, and metabolome data could be analyzed, as well as detailed annotation of microbial genomes. Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical and industrial fields. It consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics will be highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications. The book will be beneficial for researchers who study microbial genomics in universities, post-graduate and graduate programs (biology, biotechnology, medicine, genetics, microbiology, industrial and environmental microbiology, etc.), as well as the pharmaceutical and industrial sector. Presents the recent genomic developments in the industrial applications of microorganisms Summarizes recent developments in microbial genomics, emphasizing the role of next-generation sequencing in functional genomics Focus on how transcriptomics can help better understand host responses to pathogen infection Describes applications of genomics in clinical microbiology

Microbial Resources

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Publisher : Academic Press
ISBN 13 : 012805140X
Total Pages : 356 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Microbial Resources by : Ipek Kurtboke

Download or read book Microbial Resources written by Ipek Kurtboke and published by Academic Press. This book was released on 2017-03-31 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material. Covers aspects of foundational information related to microbiology, microbial ecology, and diversity, as well as new advances in microbial genomics Provides information on the utilization of microbial resources in biotechnology Covers legislative issues and related law in biodiscovery Fills a need for a very broad audience and is a good resource for microbiologists seeking to know the extent of microbiology approaches, the policies associated with microbiology, and potential career paths for researchers Has significant added value due to the inclusion of comprehensive coverage of the biology, ecology, biochemistry and international legislation surrounding these applications

Human Genetics and Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 1118537661
Total Pages : 280 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Human Genetics and Genomics by : Bruce R. Korf

Download or read book Human Genetics and Genomics written by Bruce R. Korf and published by John Wiley & Sons. This book was released on 2012-11-19 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Bugs as Drugs

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Publisher : John Wiley & Sons
ISBN 13 : 1555819702
Total Pages : 514 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Bugs as Drugs by : Robert A. Britton

Download or read book Bugs as Drugs written by Robert A. Britton and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

The Science and Applications of Microbial Genomics

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Publisher : National Academies Press
ISBN 13 : 0309268192
Total Pages : 429 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Microbial Genomics by : Institute of Medicine

Download or read book The Science and Applications of Microbial Genomics written by Institute of Medicine and published by National Academies Press. This book was released on 2013-05-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.

Medical and Health Genomics

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Publisher : Academic Press
ISBN 13 : 0127999221
Total Pages : 360 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Medical and Health Genomics by : Dhavendra Kumar

Download or read book Medical and Health Genomics written by Dhavendra Kumar and published by Academic Press. This book was released on 2016-06-04 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering

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Publisher : Elsevier
ISBN 13 : 0080475108
Total Pages : 319 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering by :

Download or read book Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering written by and published by Elsevier. This book was released on 2007-02-27 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.

Microbial Functional Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 9780471071907
Total Pages : 624 pages
Book Rating : 4.0/5 (719 download)

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Book Synopsis Microbial Functional Genomics by : Jizhong Zhou

Download or read book Microbial Functional Genomics written by Jizhong Zhou and published by John Wiley & Sons. This book was released on 2004-03-19 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Functional Genomics offers a timely summary of the principles, approaches, and applications. It presents a comprehensive review of microbial functional genomics, covering microbial diversity, microbial genome sequencing, genomic technologies, genome-wide functional analysis, applied functional genomics, and future directions. An introduction will offer a definition of the field and an overview of the historical and comparative genomics aspects.

Physiology, Genomics, and Biotechnological Applications of Extremophiles

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Publisher : IGI Global
ISBN 13 : 1799891461
Total Pages : 473 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Physiology, Genomics, and Biotechnological Applications of Extremophiles by : Gunjal, Aparna B.

Download or read book Physiology, Genomics, and Biotechnological Applications of Extremophiles written by Gunjal, Aparna B. and published by IGI Global. This book was released on 2021-12-10 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremophiles are organisms that are able to live in extreme conditions due to their unique physiological and genetic adaptations. Extremophiles are harnessed for their extremozymes that have wide applications in biotechnology, pharmaceutics, and industry. Recent developments in genomics and proteomics have helped unravel the mechanism of survival, physiological adaptation, and genomics structure of extremophiles. Physiology, Genomics, and Biotechnological Applications of Extremophiles covers innovative developments in understanding the physiology and biochemistry of extremophiles using the -omics perspective, focuses on the advancement in mechanisms of the extremophiles that makes them able to survive under extreme conditions, and discusses the applications of extremophiles in astrobiology. Covering topics such as genomics and the history and identification of extremophiles, it is ideal for students, professors, researchers, academicians, microbiologists, agricultural scientists, and biotechnologists.

Pharmaceutical industry 4.0: Future, Challenges & Application

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Publisher : CRC Press
ISBN 13 : 100096518X
Total Pages : 423 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Pharmaceutical industry 4.0: Future, Challenges & Application by : Rishabha Malviya

Download or read book Pharmaceutical industry 4.0: Future, Challenges & Application written by Rishabha Malviya and published by CRC Press. This book was released on 2023-12-14 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry is on the cusp of a new age, with the need for personalized therapy, more complex production processes, smaller batch sizes and rising manufacturing costs. It is necessary to continuously adapt to the rapidly changing environment using novel technology and improved operational efficiency and flexibility. To achieve this, intelligent manufacturing seems to be a definite answer. Pharma 4.0 is a framework for adapting digital strategies to the unique contexts of pharmaceutical manufacturing. This book provides a deep insight into key technologies that will modernize pharmaceutical manufacturing and facilitate digital transformation. Throughout the book we discuss technologies, application and challenges for applying digital technology in pharmaceutical industry, including: • Focus on an overview of Industry 4.0 and its application in the pharmaceutical field • Most recent advances in the pharmaceutical industry • Understanding the concepts of emerging technology trends for drug discovery.

Genomics: commercial opportunities from a scientific revolution

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Publisher : Taylor & Francis
ISBN 13 : 100094221X
Total Pages : 234 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Genomics: commercial opportunities from a scientific revolution by : L G Copping

Download or read book Genomics: commercial opportunities from a scientific revolution written by L G Copping and published by Taylor & Francis. This book was released on 2023-04-28 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title covers topical and unexplored issues relating to the commercial outcome of the genetic revolution which will be of great interest to both academia and industry. The book discusses whether the availability of genome sequence information will yie

Microbial Biotechnology

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Publisher : Springer
ISBN 13 : 9811071403
Total Pages : 544 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Microbial Biotechnology by : Jayanta Kumar Patra

Download or read book Microbial Biotechnology written by Jayanta Kumar Patra and published by Springer. This book was released on 2018-02-14 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book, is a collection of 25 chapters describing the recent advancements in the application of microbial technology in the food and pharmacology sector. The main focus of this book is application of microbes, food preservation techniques utilizing microbes, probiotics, seaweeds, algae, enzymatic abatement of urethane in fermentation of beverages, bioethanol production, pesticides, probiotic biosurfactants, drought tolerance, synthesis of application of oncolytic viruses in cancer treatment, microbe based metallic nanoparticles, agro chemicals, endophytes, metabolites, antibiotics etc. This book highlighted the significant aspects of the vast subject area of microbial biotechnology and their potential applications in food and pharmacology with various topics from eminent experts around the World. This book would serve as an excellent reference book for researchers and students in the Food Science, Food Biotechnology, Microbiology and Pharmaceutical fields.

WHO guidelines on use of medically important antimicrobials in food-producing animals

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Publisher : World Health Organization
ISBN 13 : 9789241550130
Total Pages : 0 pages
Book Rating : 4.5/5 (51 download)

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Book Synopsis WHO guidelines on use of medically important antimicrobials in food-producing animals by : World Health Organization

Download or read book WHO guidelines on use of medically important antimicrobials in food-producing animals written by World Health Organization and published by World Health Organization. This book was released on 2017-11-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.

Bioprospecting of Microorganism-Based Industrial Molecules

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Publisher : John Wiley & Sons
ISBN 13 : 1119717248
Total Pages : 452 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Bioprospecting of Microorganism-Based Industrial Molecules by : Sudhir P. Singh

Download or read book Bioprospecting of Microorganism-Based Industrial Molecules written by Sudhir P. Singh and published by John Wiley & Sons. This book was released on 2021-12-13 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial diversity and reveal new avenues of research investigation. Readers will also benefit from: A thorough introduction to microbial biodiversity and bioprospecting An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.

Microbial Genomics and Drug Discovery

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Publisher : CRC Press
ISBN 13 : 9780203911464
Total Pages : 272 pages
Book Rating : 4.9/5 (114 download)

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Book Synopsis Microbial Genomics and Drug Discovery by : Thomas J. Dougherty

Download or read book Microbial Genomics and Drug Discovery written by Thomas J. Dougherty and published by CRC Press. This book was released on 2003-05-14 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control, inhibition of antibacterial resistance, and acceleration of the drug discovery process. This comprehensive reference describes procedures to recognize common targets in various bacterial species for the design of broad-spectrum antibiotics and clearly illustrates the use of pathway tools in a genomics-based drug discovery project.

The 15th International Conference Interdisciplinarity in Engineering

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Publisher : Springer Nature
ISBN 13 : 3030938174
Total Pages : 869 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis The 15th International Conference Interdisciplinarity in Engineering by : Liviu Moldovan

Download or read book The 15th International Conference Interdisciplinarity in Engineering written by Liviu Moldovan and published by Springer Nature. This book was released on 2022-02-02 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains research papers that were accepted for presentation at the 15th International Conference on Interdisciplinarity in Engineering—INTER-ENG 2021, which was held on October 7–8, 2021, in the city of Târgu Mureș, Romania. The general scope of the conference “Innovative aspects of Industry 4.0 concepts aimed at consolidating the digital future of manufacturing in companies” is proposing a new approach related to the development of a new generation of smart factories grounded on the manufacturing and assembly process digitalization. It is related to advance manufacturing technology, lean manufacturing, sustainable manufacturing, additive manufacturing, and manufacturing tools and equipment. It is a leading international professional and scientific forum of great interest for engineers and scientists who can read in this book research works contributions and recent developments as well as current practices in advanced fields of engineering.

Microbes

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Publisher : John Wiley & Sons
ISBN 13 : 1118311892
Total Pages : 731 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Microbes by : Prakash S. Bisen

Download or read book Microbes written by Prakash S. Bisen and published by John Wiley & Sons. This book was released on 2012-06-22 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible introduction to the world of microbes—from basic microbe biology through industrial applications Microbes affect our lives in a variety of ways—playing an important role in our health, food, agriculture, and environment. While some microbes are beneficial, others are pathogenic or opportunistic. Microbes: Concepts and Applications describes basic microbe biology and identification and shows not only how they operate in the subfields of medicine, biotechnology, environmental science, bioengineering, agriculture, and food science, but how they can be harnessed as a resource. It provides readers with a solid grasp of etiologic agents, pathogenic processes, epidemiology, and the role of microbes as therapeutic agents. Placing a major emphasis on omics technology, the book covers recent developments in the arena of microbes and discusses their role in industry and agriculture, as well as in related fields such as immunology, cell biology, and molecular biology. It offers complete discussions of the major bacterial, viral, fungal, and parasitic pathogens; includes information on emerging infectious diseases, antibiotic resistance, and bioterrorism; and talks about the future challenges in microbiology. The most complete treatment of microbial biology available, Microbes features eye-opening chapters on: Human and Microbial World Gene Technology: Application and Techniques Molecular Diagnostic and Medical Microbiology Identification and Classification of Microbes Diversity of Microorganisms Microbes in Agriculture Microbes as a Tool for Industry and Research Complete with charts and figures, this book is an invaluable textbook for university teachers, students, researchers, and people everywhere who care about microorganisms.