Bugs As Drugs

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Bugs as Drugs

Author : Robert A. Britton
Publisher : John Wiley & Sons
ISBN 13 : 1555819702
Total Pages : 514 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Bugs as Drugs by : Robert A. Britton

Download or read book Bugs as Drugs written by Robert A. Britton and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

Drugs and Bugs - a little book about medicines

Author : Fredrik Brouneus
Publisher : BoD - Books on Demand
ISBN 13 : 918007104X
Total Pages : 41 pages
Book Rating : 4.1/5 (8 download)

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Book Synopsis Drugs and Bugs - a little book about medicines by : Fredrik Brouneus

Download or read book Drugs and Bugs - a little book about medicines written by Fredrik Brouneus and published by BoD - Books on Demand. This book was released on 2020-08-31 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Drugs and Bugs you will read about everything that is exciting about medicines - from crocodile poo and hippo fat in ancient Egypt, to today's injections and tablets. You will find out how vaccines work, why antibiotics are useless against the common cold and how scientists go about inventing new medicines. You will also learn about viruses, bacteria, fungi and parasites, how they attack the body and how we defend ourselves - both with and without medicines. And lots more! Drugs and Bugs is written by Fredrik Brouneus, pharmacist and writer. The book is richly illustrated by Nina Erixon-Lindroth, illustrator and neuroscientist.

Microbes, Bugs and Wonder Drugs

Author : Frances R. Balkwill
Publisher : Ashgate Publishing
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (97 download)

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Book Synopsis Microbes, Bugs and Wonder Drugs by : Frances R. Balkwill

Download or read book Microbes, Bugs and Wonder Drugs written by Frances R. Balkwill and published by Ashgate Publishing. This book was released on 1995 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aims to introduce the subject of disease, and the history of drugs and their use and abuse. 9-11 yrs.

Bombs, Bugs, Drugs, and Thugs

Author : Loch K. Johnson
Publisher : NYU Press
ISBN 13 : 0814771734
Total Pages : 510 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Bombs, Bugs, Drugs, and Thugs by : Loch K. Johnson

Download or read book Bombs, Bugs, Drugs, and Thugs written by Loch K. Johnson and published by NYU Press. This book was released on 2002 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Johnson, author of the acclaimed Secret Agencies and ""an experienced overseer of intelligence"" (Foreign Affairs), here examines the present state and future challenges of American strategic intelligence.

Bugs, Drugs, & Smoke

Author : World Health Organization
Publisher :
ISBN 13 : 9789241564366
Total Pages : 151 pages
Book Rating : 4.5/5 (643 download)

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Book Synopsis Bugs, Drugs, & Smoke by : World Health Organization

Download or read book Bugs, Drugs, & Smoke written by World Health Organization and published by . This book was released on 2011 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the World Health Organization (WHO) was founded in 1948, the world has changed dramatically and so too has its health. But while some scourges (e.g. smallpox and polio) have subsided, others have made a comeback (e.g. tuberculosis) and frightening new diseases (e.g. Ebola and Marburg) have appeared. This book is primarily for young people, especially those interested in working in public health. It explains in simple, non-technical language how humankind developed techniques to protect the health of communities, drawing on first-hand interviews with leading public health figures. It covers a wide range of topics, from the control of infectious disease outbreaks to fighting the stigma attached to mental health conditions. These narratives, told from many parts of the world, show how individuals, communities, institutions and countries can improve people's health when they work together. They show the role that WHO has played in providing countries with the technical support and coordination to make progress in health possible.

Thugs, Drugs and the War on Bugs

Author : Brad Case
Publisher :
ISBN 13 : 9780981989501
Total Pages : 0 pages
Book Rating : 4.9/5 (895 download)

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Book Synopsis Thugs, Drugs and the War on Bugs by : Brad Case

Download or read book Thugs, Drugs and the War on Bugs written by Brad Case and published by . This book was released on 2010-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is the number one killer in the United States? Medical treatment. Western medicine has cures for surprisingly few diseases and actually causes illness with its drugs for every disease approach. Infectious diseases are making a comeback due to the overuse of antibiotics and our war on germs. We've seen an exponential rise in autism while vaccinating more than any other country. According to the Journal of the American Medical Association, properly prescribed medication is the fourth leading cause of death, hospitals are the third, and medical doctors kill more than all other forms of accidental death combined. This first book in the Why We're Sick series exposes the myths, lies, greed, and just plain bungling that is the untold story of Western medicine. Deeply researched, deadly serious, yet often humorous and irreverent, no other work so thoroughly explains how we got into this mess and what we can do to be truly healthy.

Superbugs

Author : William Hall
Publisher : Harvard University Press
ISBN 13 : 0674985079
Total Pages : 236 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis Superbugs by : William Hall

Download or read book Superbugs written by William Hall and published by Harvard University Press. This book was released on 2018-04-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.

The Bad Bug Book

Author : FDA
Publisher : Imp
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Bad Bug Book by : FDA

Download or read book The Bad Bug Book written by FDA and published by Imp. This book was released on 2004 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bad Bug was created from the materials assembled at the FDA website of the same name. This handbook provides basic facts regarding foodborne pathogenic microorganisms and natural toxins. It brings together in one place information from the Food & Drug Administration, the Centers for Disease Control & Prevention, the USDA Food Safety Inspection Service, and the National Institutes of Health.

Good Germs, Bad Germs

Author : Jessica Snyder Sachs
Publisher : Hill and Wang
ISBN 13 : 1429923296
Total Pages : 304 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Good Germs, Bad Germs by : Jessica Snyder Sachs

Download or read book Good Germs, Bad Germs written by Jessica Snyder Sachs and published by Hill and Wang. This book was released on 2008-09-30 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making Peace with Microbes Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"— an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes—which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones—each custom-designed for maximum health benefits.

Viruses Vs. Superbugs

Author : T. Häusler
Publisher : Springer
ISBN 13 : 0230552285
Total Pages : 307 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Viruses Vs. Superbugs by : T. Häusler

Download or read book Viruses Vs. Superbugs written by T. Häusler and published by Springer. This book was released on 2016-05-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.

How to Fight Harmful Microbial Bugs and Superbugs?

Author : Alain Fischer
Publisher : Frontiers Media SA
ISBN 13 : 2889714667
Total Pages : 209 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis How to Fight Harmful Microbial Bugs and Superbugs? by : Alain Fischer

Download or read book How to Fight Harmful Microbial Bugs and Superbugs? written by Alain Fischer and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolution of human beings has been shaped to a large extent by microbes. A number of microbes are innocuous or even contribute to our health equilibrium. This is the case of bacteria and viral phages present in our gut. However, several bacteria, viruses, parasites, and fungi are damaging our bodies, causing a number of acute and chronic diseases. Until recently, these bugs represented the main causes of death. Better hygiene, vaccines, antibiotics and other anti-microbial drugs have resulted in a better control or cure of many infections. However, malaria, tuberculosis, and AIDS still represent major threats in several countries and the recent epidemics of Ebola and Zika demonstrate how vulnerable we are to newly emerging viruses. Furthermore, diarrhea and pneumonia caused by bacteria or viruses still kill millions of children worldwide. Most importantly, bacteria resistant to existing antibiotics are multiplying at a high pace and these superbugs are expected to kill more and more people in the coming years. Clearly, we need to develop more effective approaches to tackle bugs and superbugs. Better hygiene and better vaccine coverage must be considered first and education of kids is essential in this respect. This is the main objective of this series of papers published in Frontiers for Young Minds under the heading “How to Fight Harmful Microbial Bugs and Superbugs?”. Another key objective of the collection is to elicit the interest of children for research on innovative anti-microbial therapies and vaccines.

Natural Defense

Author : Emily Monosson
Publisher : Island Press
ISBN 13 : 1610917189
Total Pages : 199 pages
Book Rating : 4.6/5 (19 download)

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Book Synopsis Natural Defense by : Emily Monosson

Download or read book Natural Defense written by Emily Monosson and published by Island Press. This book was released on 2017-06-20 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: We rely on chemical cures to keep our bodies free from disease and our farms free from bugs and weeds. While human and agricultural health are rarely considered together, both are based on the same ecology, and both are being threatened by organisms that have evolved to resist our antibiotics and pesticides. Fortunately, scientists are finding new solutions that work with, rather than against, nature. There are viruses that bust apart bacteria; insect pheromones that throw crop-destroying moths into a misguided sexual frenzy; plant genes edited to protect against disease; and a resurgence of the ancient practice of fecal transplants. In this hopeful book, Monosson offers a fascinating look into the future of natural defenses.

Microbial Threats to Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309185548
Total Pages : 397 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Threats to Health by : Institute of Medicine

Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

The Drugs Don't Work

Author : Professor Dame Sally Davies
Publisher : Penguin UK
ISBN 13 : 0241968887
Total Pages : 50 pages
Book Rating : 4.2/5 (419 download)

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Book Synopsis The Drugs Don't Work by : Professor Dame Sally Davies

Download or read book The Drugs Don't Work written by Professor Dame Sally Davies and published by Penguin UK. This book was released on 2013-09-15 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for England 'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren. Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food. No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall. Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College. Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics. Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.

The Antibiotic Era

Author : Scott H. Podolsky
Publisher : JHU Press
ISBN 13 : 1421415933
Total Pages : 324 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis The Antibiotic Era by : Scott H. Podolsky

Download or read book The Antibiotic Era written by Scott H. Podolsky and published by JHU Press. This book was released on 2015-01-15 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the post-World War II "wonder drug" revolution, antibiotics were viewed as a panacea for mastering infectious disease. This book narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed

Treatment of Bone and Soft Tissue Sarcomas

Author : Per-Ulf Tunn
Publisher : Springer Science & Business Media
ISBN 13 : 3540779604
Total Pages : 372 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Treatment of Bone and Soft Tissue Sarcomas by : Per-Ulf Tunn

Download or read book Treatment of Bone and Soft Tissue Sarcomas written by Per-Ulf Tunn and published by Springer Science & Business Media. This book was released on 2008-12-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Superbugs

Author : Matt McCarthy
Publisher : Penguin
ISBN 13 : 0735217521
Total Pages : 304 pages
Book Rating : 4.7/5 (352 download)

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Book Synopsis Superbugs by : Matt McCarthy

Download or read book Superbugs written by Matt McCarthy and published by Penguin. This book was released on 2019-05-21 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?