Microbial Evolution

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Publisher :
ISBN 13 : 9781621820376
Total Pages : 0 pages
Book Rating : 4.8/5 (23 download)

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Book Synopsis Microbial Evolution by : Howard Ochman

Download or read book Microbial Evolution written by Howard Ochman and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria have been the dominant forms of life on Earth for the past 3.5 billion years. They rapidly evolve, constantly changing their genetic architecture through horizontal DNA transfer and other mechanisms. Consequently, it can be difficult to define individual species and determine how they are related. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines how bacteria and other microbes evolve, focusing on insights from genomics-based studies. Contributors discuss the origins of new microbial populations, the evolutionary and ecological mechanisms that keep species separate once they have diverged, and the challenges of constructing phylogenetic trees that accurately reflect their relationships. They describe the organization of microbial genomes, the various mutations that occur, including the birth of new genes de novo and by duplication, and how natural selection acts on those changes. The role of horizontal gene transfer as a strong driver of microbial evolution is emphasized throughout. The authors also explore the geologic evidence for early microbial evolution and describe the use of microbial evolution experiments to examine phenomena like natural selection. This volume will thus be essential reading for all microbial ecologists, population geneticists, and evolutionary biologists.

Molecular Mechanisms of Microbial Evolution

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Publisher : Springer
ISBN 13 : 3319690787
Total Pages : 448 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Molecular Mechanisms of Microbial Evolution by : Pabulo H. Rampelotto

Download or read book Molecular Mechanisms of Microbial Evolution written by Pabulo H. Rampelotto and published by Springer. This book was released on 2018-10-12 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most profound paradigms that have transformed our understanding about life over the last decades was the acknowledgement that microorganisms play a central role in shaping the past and present environments on Earth and the nature of all life forms. Each organism is the product of its history and all extant life traces back to common ancestors, which were microorganisms. Nowadays, microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. Microbial evolution occurred and continues to take place in a great variety of environmental conditions. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. In addition, the molecular mechanisms by which microorganisms communicate/interact with each other and with multicellular organisms remains poorly understood. Such patterns of microbe-host interaction are essential to understand the evolution of microbial symbiosis and pathogenesis.Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health. Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.

Microbial Evolution and Co-Adaptation

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Publisher : National Academies Press
ISBN 13 : 0309131219
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine

Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

Microbial Evolution under Extreme Conditions

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110340712
Total Pages : 290 pages
Book Rating : 4.1/5 (13 download)

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Book Synopsis Microbial Evolution under Extreme Conditions by : Corien Bakermans

Download or read book Microbial Evolution under Extreme Conditions written by Corien Bakermans and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-03-10 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today's microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. Microbial evolution occurred and continues to take place in a vast variety of environmental conditions that range from anoxic to oxic, from hot to cold, from free-living to symbiotic, etc. Some of these physicochemical conditions are considered "extreme", particularly when inhabitants are limited to microorganisms. It is easy to imagine that microbial life in extreme environments is somehow more constrained and perhaps subjected to different evolutionary pressures. But what do we actually know about microbial evolution under extreme conditions and how can we apply that knowledge to other conditions? Appealingly, extreme environments with their relatively limited numbers of inhabitants can serve as good model systems for the study of evolutionary processes. A look at the microbial inhabitants of today's extreme environments provides a snapshot in time of evolution and adaptation to extreme conditions. These adaptations manifest at different levels from established communities and species to genome content and changes in specific genes that result in altered function or gene expression. But as a recent (2011) report from the American Academy of Microbiology observes: "A complex issue in the study of microbial evolution is unraveling the process of evolution from that of adaptation. In many cases, microbes have the capacity to adapt to various environmental changes by changing gene expression or community composition as opposed to having to evolve entirely new capabilities." We have learned much about how microbes are adapted to extreme conditions but relatively little is known about these adaptations evolved. How did the different processes of evolution such as mutation, immigration, horizontal (lateral) gene transfer, recombination, hybridization, genetic drift, fixation, positive and negative selection, and selective screens contribute to the evolution of these genes, genomes, microbial species, communities, and functions? What are typical rates of these processes? How prevalent are each of these processes under different conditions? This book explores the current state of knowledge about microbial evolution under extreme conditions and addresses the following questions: What is known about the processes of microbial evolution (mechanisms, rates, etc.) under extreme conditions? Can this knowledge be applied to other systems and what is the broader relevance? What remains unknown and requires future research? These questions will be addressed from several perspectives including different extreme environments, specific organisms, and specific evolutionary processes.

Microcosmos

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Publisher : Univ of California Press
ISBN 13 : 0520340515
Total Pages : 304 pages
Book Rating : 4.5/5 (23 download)

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Book Synopsis Microcosmos by : Lynn Margulis

Download or read book Microcosmos written by Lynn Margulis and published by Univ of California Press. This book was released on 2023-04-28 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Microcosmos is nothing less than the saga of the life of the planet. Lynn Margulis and Dorion Sagan have put it all together, literally, in this extraordinary book, which is unlike any treatment of evolution for a general readership that I have encountered before. A fascinating account that we humans should be studying now for clues to our own survival."—From the Foreword by Dr. Lewis Thomas Microcosmos brings together the remarkable discoveries of microbiology in the later decades of the 20th century and the pioneering research of Dr. Margulis to create a vivid new picture of the world that is crucial to our understanding of the future of the planet. Addressed to general readers, the book provides a beautifully written view of evolution as a process based on interdependency and their interconnectedness of all life on the planet.

The Hologenome Concept: Human, Animal and Plant Microbiota

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Publisher : Springer Science & Business Media
ISBN 13 : 3319042416
Total Pages : 187 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis The Hologenome Concept: Human, Animal and Plant Microbiota by : Eugene Rosenberg

Download or read book The Hologenome Concept: Human, Animal and Plant Microbiota written by Eugene Rosenberg and published by Springer Science & Business Media. This book was released on 2014-01-31 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

The Social Biology of Microbial Communities

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Publisher : National Academies Press
ISBN 13 : 0309264324
Total Pages : 633 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Social Biology of Microbial Communities by : Institute of Medicine

Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.

The New Science of Metagenomics

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Publisher : National Academies Press
ISBN 13 : 0309106761
Total Pages : 170 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The New Science of Metagenomics by : National Research Council

Download or read book The New Science of Metagenomics written by National Research Council and published by National Academies Press. This book was released on 2007-06-24 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.

Links Between Geological Processes, Microbial Activities & Evolution of Life

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Publisher : Springer Science & Business Media
ISBN 13 : 1402083068
Total Pages : 359 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Links Between Geological Processes, Microbial Activities & Evolution of Life by : Yildirim Dilek

Download or read book Links Between Geological Processes, Microbial Activities & Evolution of Life written by Yildirim Dilek and published by Springer Science & Business Media. This book was released on 2008-07-01 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial systems in extreme environments and in the deep biosphere may be analogous to potential life on other planetary bodies and hence may be used to investigate the possibilities of extraterrestrial life. This book examines the mode and nature of links between geological processes and microbial activities and their significance for the origin and evolution of life on the Earth and possibly on other planets. This is a truly interdisciplinary science with societal relevance.

Genetics and Evolution of Infectious Diseases

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Publisher : Elsevier
ISBN 13 : 0123848903
Total Pages : 773 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc and published by Elsevier. This book was released on 2010-12-17 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Microbes and Evolution

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Publisher :
ISBN 13 : 9781555815400
Total Pages : 0 pages
Book Rating : 4.8/5 (154 download)

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Book Synopsis Microbes and Evolution by : Roberto Kolter

Download or read book Microbes and Evolution written by Roberto Kolter and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the fundamental role of microbes in the natural history of our planet with 40 first-person essays written by microbiologists with a passion for evolutionary biology, whose thinking and career paths in science were influenced by Darwin's seminal work On the Origin of Species.

Microbes

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Publisher : Rowman & Littlefield
ISBN 13 : 1633886352
Total Pages : 314 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis Microbes by : Phillip K. Peterson

Download or read book Microbes written by Phillip K. Peterson and published by Rowman & Littlefield. This book was released on 2020-08-08 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book that tells both sides of the story of germs: that they are critically important for our health and that the dangers of emerging pathogens continue to wreak havoc in our bodies and around the world. With straight-forward and engaging writing, infectious diseases physician Phillip Peterson surveys how our understanding of viruses has changed throughout history, from early plagues and pandemics to more recent outbreaks like HIV/AIDS, Ebola, Zika, and Coronavirus. Microbes also takes on contemporary issues like the importance of vaccinations in the face of the growing anti-vaxxer movement, as well as the rise of cutting-edge health treatments like fecal transplants. Peterson relays his first-hand experience dealing with an unprecedented emergence of new microbial threats. Yet at the same time he has witnessed the astounding recent discoveries of the crucial role of the microbes that colonize our body surfaces in human health. Microbes explains for general readers where these germs came from, what they do to and for us, and what can be done to stop the bad actors and foster the benefactors.

Evolution of Virulence in Eukaryotic Microbes

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Publisher : John Wiley & Sons
ISBN 13 : 1118308131
Total Pages : 912 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Evolution of Virulence in Eukaryotic Microbes by : L. David Sibley

Download or read book Evolution of Virulence in Eukaryotic Microbes written by L. David Sibley and published by John Wiley & Sons. This book was released on 2012-06-07 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique and timely review of the emergence of eukaryotic virulence in fungi, oomycetes, and protozoa, as they affect both animals and plants Evolution of Virulence in Eukaryotic Microbes addresses new developments in defining the molecular basis of virulence in eukaryotic pathogens. By examining how pathogenic determinants have evolved in concert with their hosts, often overcoming innate and adaptive immune mechanisms, the book takes a fresh look at the selective processes that have shaped their evolution. Introductory chapters ground the reader in principal evolutionary themes such as phylogenetics and genetic exchange, building a basis of knowledge for later chapters covering advances in genetic tools, how pathogens exchange genetic material in nature, and the common themes of evolutionary adaptation that lead to disease in different hosts. With the goal of linking the research findings of the many disparate scientific communities in the field, the book: Assembles for the first time a collection of chapters on the diversity of eukaryotic microorganisms and the influence of evolutionary forces on the origins and emergence of their virulent attributes Highlights examples from three important, divergent groups of eukaryotic microorganisms that cause disease in animals and plants: oomycetes, protozoan parasites, and fungi Covers how the development of genetic tools has fostered the identification and functional analyses of virulence determinants Addresses how pathogens exchange genetic material in nature via classical or modified meiotic processes, horizontal gene transfer, and sexual cycles including those that are cryptic or even unisexual Provides a broad framework for formulating future studies by illustrating themes common to different pathogenic microbes Evolution of Virulence in Eukaryotic Microbes is an ideal book for microbiologists, evolutionary biologists and medical professionals, as well as graduate students, postdoctoral fellows, and faculty members working on the evolution of pathogens.

Evolution

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Publisher : Academic Press
ISBN 13 : 0128004177
Total Pages : 206 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Evolution by : David Zeigler

Download or read book Evolution written by David Zeigler and published by Academic Press. This book was released on 2014-04-14 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution: Components and Mechanisms introduces the many recent discoveries and insights that have added to the discipline of organic evolution, and combines them with the key topics needed to gain a fundamental understanding of the mechanisms of evolution. Each chapter covers an important topic or factor pertinent to a modern understanding of evolutionary theory, allowing easy access to particular topics for either study or review. Many chapters are cross-referenced. Modern evolutionary theory has expanded significantly within only the past two to three decades. In recent times the definition of a gene has evolved, the definition of organic evolution itself is in need of some modification, the number of known mechanisms of evolutionary change has increased dramatically, and the emphasis placed on opportunity and contingency has increased. This book synthesizes these changes and presents many of the novel topics in evolutionary theory in an accessible and thorough format. This book is an ideal, up-to-date resource for biologists, geneticists, evolutionary biologists, developmental biologists, and researchers in, as well as students and academics in these areas and professional scientists in many subfields of biology. Discusses many of the mechanisms responsible for evolutionary change Includes an appendix that provides a brief synopsis of these mechanisms with most discussed in greater detail in respective chapters Aids readers in their organization and understanding of the material by addressing the basic concepts and topics surrounding organic evolution Covers some topics not typically addressed, such as opportunity, contingency, symbiosis, and progress

Man and Microbes

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Publisher : Simon and Schuster
ISBN 13 : 0684822709
Total Pages : 276 pages
Book Rating : 4.6/5 (848 download)

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Book Synopsis Man and Microbes by : Arno Karlen

Download or read book Man and Microbes written by Arno Karlen and published by Simon and Schuster. This book was released on 1996-05-22 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: A noted medical historian places recent outbreaks of deadly diseases in historical perspective, with accounts of other alarming and recurring diseases throughout history and of the ways in which humans have adapted. Reprint. 17,500 first printing.

Defensive Mutualism in Microbial Symbiosis

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Publisher : CRC Press
ISBN 13 : 9781420069327
Total Pages : 430 pages
Book Rating : 4.0/5 (693 download)

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Book Synopsis Defensive Mutualism in Microbial Symbiosis by : James F. White Jr.

Download or read book Defensive Mutualism in Microbial Symbiosis written by James F. White Jr. and published by CRC Press. This book was released on 2009-05-26 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anemones and fish, ants and acacia trees, fungus and trees, buffaloes and oxpeckers--each of these unlikely duos is an inimitable partnership in which the species’ coexistence is mutually beneficial. More specifically, they represent examples of defensive mutualism, when one species receives protection against predators or parasites in exchange for offering shelter or food to its partner species. Explores the Diverse Range of Defensive Mutualisms Involving Microbial Symbionts The past 20 years, since this phenomenon first began receiving attention, have been marked by a deluge of research in a variety of organism kingdoms and much has been discovered about this intriguing behavior. Defensive Mutualism in Microbial Symbiosis includes basic ecological and biological information on defensive mutualisms, explores how they function, and evaluates how they have evolved. It also looks at the implications of symbiosis defensive compounds as a new frontier in bioexploration for drug and natural product discovery--the first book to explore this possibility. Chapters Written by Field Authorities The book expands the concept of defensive mutualisms to evaluate defense against environmental abiotic and biotic stresses. Addressing the topic of defensive mutualisms in microbial symbiosis across this wide spectrum, it includes chapters on defensive mutualistic associations involving multiple kingdoms of organisms in terrestrial and aquatic ecosystems--plant, animal, fungi, bacteria, and protozoans. Defensive Mutualism in Microbial Symbiosis unifies scattered findings into a single compendium, providing a valuable reference for field researchers and those in academia to assimilate and acquire a knowledgeable perspective on defensive mutualism, particularly those involving microbial partners.

Polyextremophiles

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Publisher : Springer Science & Business Media
ISBN 13 : 940076488X
Total Pages : 626 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Polyextremophiles by : Joseph Seckbach

Download or read book Polyextremophiles written by Joseph Seckbach and published by Springer Science & Business Media. This book was released on 2013-05-13 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many Microorganisms and some macro-organisms can live under extreme conditions. For example, high and low temperature, acidic and alkaline conditions, high salt areas, high pressure, toxic compounds, high level of ionizing radiation, anoxia and absence of light, etc. Many organisms inhabit environments characterized by more than one form of stress (Polyextremophiles). Among them are those who live in hypersaline and alkaline, hot and acidic, cold/hot and high hydrostatic pressure, etc. Polyextremophiles found in desert regions have to copy with intense UV irradiation and desiccation, high as well as low temperatures, and low availability of water and nutrients. This book provides novel results of application to polyextremophiles research ranging from nanotechnology to synthetic biology to the origin of life and beyond.