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Micro And Nanofluidic Devices For Complexed Dna Analysis At The Single Molecule Level
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Book Synopsis Micro- and Nanomanipulation Tools by : Yu Sun
Download or read book Micro- and Nanomanipulation Tools written by Yu Sun and published by John Wiley & Sons. This book was released on 2015-11-23 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Das erste Handbuch, das Robotertechnik und Nanotechnologie verbindet, als Nachschlagewerk die Grundlagen zusammenfasst und neue Anwendungen in den Bereichen Halbleiter-Packaging, klinische Diagnose und Chirurgie vorstellt. Durchgängig mit aufregenden Aufnahmen auf Nanoebene.
Book Synopsis Single Molecule Analysis by : Iddo Heller
Download or read book Single Molecule Analysis written by Iddo Heller and published by Springer Nature. This book was released on 2023-11-13 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition volume expands on the previous editions with new discussions on the latest techniques and developments in the field. The chapters in this book are organized into four parts, and cover topics such as optical tweezers; single-molecule fluorescence tools; atomic force microscopy; magnetic tweezers; applications to virus protein shells, unfolding of proteins, nucleic acids, motor proteins, in vivo and in vitro; and protocols to establish specific surface interactions and perform force calibration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Single Molecule Analysis: Methods and Protocols, Third Edition is a valuable resource for all researchers who want to learn more about this exciting and still expanding field. Chapters 2, 7, 8, 9, 12, 18, and 19 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Electrokinetic Particle Transport in Micro-/Nanofluidics by : Shizhi Qian
Download or read book Electrokinetic Particle Transport in Micro-/Nanofluidics written by Shizhi Qian and published by CRC Press. This book was released on 2012-06-19 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous applications of micro-/nanofluidics are related to particle transport in micro-/nanoscale channels, and electrokinetics has proved to be one of the most promising tools to manipulate particles in micro/nanofluidics. Therefore, a comprehensive understanding of electrokinetic particle transport in micro-/nanoscale channels is crucial to the development of micro-/nanofluidic devices. Electrokinetic Particle Transport in Micro-/Nanofluidics: Direct Numerical Simulation Analysis provides a fundamental understanding of electrokinetic particle transport in micro-/nanofluidics involving electrophoresis, dielectrophoresis, electroosmosis, and induced-charge electroosmosis. The book emphasizes the direct numerical simulation of electrokinetic particle transport phenomena, plus several supportive experimental studies. Using the commercial finite element package COMSOL Multiphysics®, it guides researchers on how to predict the particle transport subjected to electric fields in micro-/nanoscale channels. Researchers in the micro-/nanofluidics community, who may have limited experience in writing their own codes for numerical simulations, can extend the numerical models and codes presented in this book to their own research and guide the development of real micro-/nanofluidics devices. Corresponding COMSOL® script files are provided with the book and can be downloaded from the author’s website.
Book Synopsis Single Cell Analysis by : Tuhin Subhra Santra
Download or read book Single Cell Analysis written by Tuhin Subhra Santra and published by MDPI. This book was released on 2021-06-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells are the most fundamental building block of all living organisms. The investigation of any type of disease mechanism and its progression still remains challenging due to cellular heterogeneity characteristics and physiological state of cells in a given population. The bulk measurement of millions of cells together can provide some general information on cells, but it cannot evolve the cellular heterogeneity and molecular dynamics in a certain cell population. Compared to this bulk or the average measurement of a large number of cells together, single-cell analysis can provide detailed information on each cell, which could assist in developing an understanding of the specific biological context of cells, such as tumor progression or issues around stem cells. Single-cell omics can provide valuable information about functional mutation and a copy number of variations of cells. Information from single-cell investigations can help to produce a better understanding of intracellular interactions and environmental responses of cellular organelles, which can be beneficial for therapeutics development and diagnostics purposes. This Special Issue is inviting articles related to single-cell analysis and its advantages, limitations, and future prospects regarding health benefits.
Book Synopsis Essentials of Micro- and Nanofluidics by : A. Terrence Conlisk
Download or read book Essentials of Micro- and Nanofluidics written by A. Terrence Conlisk and published by Cambridge University Press. This book was released on 2013 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces students to the basic physical principles to analyze fluid flow in micro and nano-size devices. This is the first book that unifies the thermal sciences with electrostatics and electrokinetics and colloid science; electrochemistry; and molecular biology. The author discusses key concepts and principles, such as the essentials of viscous flows, an introduction to electrochemistry, heat and mass transfer phenomena, elements of molecular and cell biology, and much more. This textbook presents state-of-the-art analytical and computational approaches to problems in all of these areas, especially electrokinetic flows, and gives examples of the use of these disciplines to design devices used for rapid molecular analysis, biochemical sensing, drug delivery, DNA analysis, the design of an artificial kidney, and other transport phenomena. This textbook includes exercise problems, modern examples of the applications of these sciences, and a solutions manual available to qualified instructors.
Book Synopsis Nanobiosensors and Nanobioanalyses by : Mun'delanji C. Vestergaard
Download or read book Nanobiosensors and Nanobioanalyses written by Mun'delanji C. Vestergaard and published by Springer. This book was released on 2015-03-18 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of established, cutting-edge, and future trends in the exponentially growing field of nanomaterials and their applications in biosensors and bioanalyses. Part I focuses on the key principles and transduction approaches, reviewing the timeline featuring the important historical milestones in the development and application of nanomaterials in biosensors and bioanalyses. Part II reviews various architectures used in nanobiosensing designs focusing on nanowires, one- and two-dimensional nanostructures, and plasmonic nanobiosensors with interferometric reflectance imaging. Commonly used nanomaterials, functionalization of the nanomaterials, and development of nanobioelectronics are discussed in detail in Part III with examples from screen-printed electrodes, nanocarbon films, and semiconductor quantum dots. Part IV reviews the current applications of carbon nanotubes, nanoneedles, plasmonic sensors, electrochemical scanning microscopes, and field-effect transistors with the future outlook for emerging technologies. Attention is also given to potential challenges, in particular, of taking these technologies at the point-of-need. The book concludes by providing a condensed summary of the contents, with emphasis on future directions. Nanomaterials have become an essential part of biosensors and bioanalyses in the detection and monitoring of medical, pharmaceutical, and environmental conditions, from cancer to chemical warfare agents. This book, with its distinguished editors and international team of expert contributors, will be an essential guide for all those involved in the research, design, development, and application of nanomaterials in biosensors and bioanalyses.
Book Synopsis New Frontiers in Ultrasensitive Bioanalysis by : Xiao-Hong Nancy Xu
Download or read book New Frontiers in Ultrasensitive Bioanalysis written by Xiao-Hong Nancy Xu and published by John Wiley & Sons. This book was released on 2007-06-04 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current research and developments in ultrasensitive bioanalysis New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace. With chapters written by a diverse group of scientists working in the forefront of ultrasensitive bioanalysis, this book provides an overview of the current status and an in-depth understanding of the objectives and future research directions of ultrasensitive bioanalysis. Spanning a wide spectrum of new research approaches, this book: Introduces new theories, ideas, methodologies, technologies, and applications of ultrasensitive bioanalysis in a wide variety of research fields Includes background, fundamentals, and descriptions of instrumentation and techniques behind every experimental design and approach to help readers explore the promising applications of new tools Covers single molecule detection (SMD), single living cell analysis, multi-functional nanoparticle probes, miniaturization, multiplexing, quantitative and qualitative analysis of metal ions and small molecules, and more Discusses techniques such as single molecule microscope and spectroscopy, single nanoparticle optics, single nanoparticle sensors, micro- and nano-fluidics, microarray detection, ultramicroelectrodes, electrochemiluminescence, mass spectrometry, and more This book will be a useful resource and an inspiration for scientists and graduate and undergraduate students in a wide variety of research fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering.
Book Synopsis Cell Analysis on Microfluidics by : Jin-Ming Lin
Download or read book Cell Analysis on Microfluidics written by Jin-Ming Lin and published by Springer. This book was released on 2017-10-25 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.
Book Synopsis Molecular Genetic Pathology by : Liang Cheng
Download or read book Molecular Genetic Pathology written by Liang Cheng and published by Springer. This book was released on 2013-03-05 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
Book Synopsis Micro and Nano Technologies in Bioanalysis by : James W. Lee
Download or read book Micro and Nano Technologies in Bioanalysis written by James W. Lee and published by Methods in Molecular Biology. This book was released on 2009-07-21 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, large-scale advances in technology have led to greater understanding of the world at the biomolecular level. In this book, expert researchers from across the globe explore the technology which makes this analysis possible.
Book Synopsis Nanoplasmonic Sensors by : Alexandre Dmitriev
Download or read book Nanoplasmonic Sensors written by Alexandre Dmitriev and published by Springer Science & Business Media. This book was released on 2012-07-31 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of the finest research in nanoplasmonic sensing done around the world in the last decade. It describes basic theoretical considerations of nanoplasmons in the dielectric environment, gives examples of the multitude of applications of nanoplasmonics in biomedical and chemical sensing, and provides an overview of future trends in optical and non-optical nanoplasmonic sensing. Specifically, readers are guided through both the fundamentals and the latest research in the two major fields nanoplasmonic sensing is applied to – bio- and chemo-sensing – then given the state-of-the-art recipes used in nanoplasmonic sensing research.
Book Synopsis Diagnostic Molecular Biology by : Chang-Hui Shen
Download or read book Diagnostic Molecular Biology written by Chang-Hui Shen and published by Elsevier. This book was released on 2023-06-29 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine. - Provides explanations on how techniques are used to diagnosis at the molecular level - Explains how to use information technology to communicate and assess results in the lab - Enhances our understanding of fundamental molecular biology and places techniques in context - Places protocols into context with practical applications - Includes extra chapters on respiratory viruses (Corona)
Book Synopsis Microfluidics and BioMEMS by : Tuhin Subhra Santra
Download or read book Microfluidics and BioMEMS written by Tuhin Subhra Santra and published by . This book was released on 2020-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. It also elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-NEMS, biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical microdevices.
Book Synopsis Nanolithography and Patterning Techniques in Microelectronics by : D Bucknall
Download or read book Nanolithography and Patterning Techniques in Microelectronics written by D Bucknall and published by Elsevier. This book was released on 2005-09-30 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Techniques such as surface patterning have facilitated the emergence of advanced polymers with applications in areas such as microelectronics. Surface patterning of polymers has conventionally been undertaken by optical lithography. However, a new generation of nanolithographic and patterning techniques has made it possible to develop complex patterns at the nanoscale. Non-conventional lithography and patterning summarises this new range of techniques and their industrial applications.A number of chapters look at ways of forming and modifying surfaces for patterning. These are complemented by chapters on particular patterning techniques such as soft lithography, ion beam patterning, the use of nanostencils, photolithography and inkjet printing. The book also discusses prototyping and the manufacture of particular devices.With its distinguished international team of contributors, Non-conventional lithography and patterning is a standard reference for both those researching and using advanced polymers in such areas as microelectronics and biomedical devices. - Looks at alternative approaches used to develop complex patterns at the nanoscale - Concentrates on state of the art nanolithographic methods - Written by a distinguished international team of contributors
Book Synopsis Spectroscopy and Dynamics of Single Molecules by :
Download or read book Spectroscopy and Dynamics of Single Molecules written by and published by Elsevier. This book was released on 2019-08-14 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopy and Dynamics of Single Molecules: Methods and Applications reviews the most recent developments in spectroscopic methods and applications. Spectroscopic techniques are the chief experimental methods for testing theoretical models and research in this area plays an important role in stimulating new theoretical developments in physical chemistry. This book provides an authoritative insight into the latest advances in the field, highlighting new techniques, current applications, and potential future developments An ideal reference for chemists and physicists alike, Spectroscopy and Dynamics of Single Molecules: Methods and Applications is a useful guide for all those working in the research, design, or application of spectroscopic tools and techniques across a wide range of fields. - Includes the latest research on ultrafast vibrational and electronic dynamics, nonlinear spectroscopies, and single-molecule methods - Makes the content accessible to researchers in chemistry, biophysics, and chemical physics through a rigorous multi-disciplinary approach - Provides content edited by a world-renowned chemist with more than 30 years of experience in research and instruction
Book Synopsis Basic Physical Pharmacy by : Joseph K. H. Ma
Download or read book Basic Physical Pharmacy written by Joseph K. H. Ma and published by Jones & Bartlett Publishers. This book was released on 2013 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Physical Pharmacy provides a thorough yet accessible overview of the principles of physical pharmacy and their application in drug formulation and administration. This definitive guide to physical pharmacy covers all types of pharmaceuticals, from traditional forms and dosages to nanotechnology-based novel dosage design.
Book Synopsis Theoretical Microfluidics by : Henrik Bruus
Download or read book Theoretical Microfluidics written by Henrik Bruus and published by Oxford University Press. This book was released on 2007-09-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics is a young and rapidly expanding scientific discipline, which deals with fluids and solutions in miniaturized systems, the so-called lab-on-a-chip systems. It has applications in chemical engineering, pharmaceutics, biotechnology and medicine. As the lab-on-a-chip systems grow in complexity, a proper theoretical understanding becomes increasingly important. The basic idea of the book is to provide a self-contained formulation of the theoretical framework of microfluidics, and at the same time give physical motivation and examples from lab-on-a-chip technology. After three chapters introducing microfluidics, the governing equations for mass, momentum and energy, and some basic flow solutions, the following 14 chapters treat hydraulic resistance/compliance, diffusion/dispersion, time-dependent flow, capillarity, electro- and magneto-hydrodynamics, thermal transport, two-phase flow, complex flow patterns and acousto-fluidics, as well as the new fields of opto- and nano-fluidics. Throughout the book simple models with analytical solutions are presented to provide the student with a thorough physical understanding of order of magnitudes and various selected microfluidic phenomena and devices. The book grew out of a set of well-tested lecture notes. It is with its many pedagogical exercises designed as a textbook for an advanced undergraduate or first-year graduate course. It is also well suited for self-study.
