Metallothionein IV

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Author :
Publisher : Birkhäuser
ISBN 13 : 3034888473
Total Pages : 641 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Metallothionein IV by : C. Klaasen

Download or read book Metallothionein IV written by C. Klaasen and published by Birkhäuser. This book was released on 2012-12-06 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.

Metallothioneins and Related Chelators

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110436272
Total Pages : 544 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Metallothioneins and Related Chelators by : Astrid Sigel

Download or read book Metallothioneins and Related Chelators written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-07-24 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.

Metallothioneins in Biochemistry and Pathology

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Author :
Publisher : World Scientific
ISBN 13 : 9812778942
Total Pages : 335 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis Metallothioneins in Biochemistry and Pathology by : Paolo Zatta

Download or read book Metallothioneins in Biochemistry and Pathology written by Paolo Zatta and published by World Scientific. This book was released on 2008 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.

Nanoscopic Materials

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849739072
Total Pages : 938 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Nanoscopic Materials by : Emil Roduner

Download or read book Nanoscopic Materials written by Emil Roduner and published by Royal Society of Chemistry. This book was released on 2014-08-12 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible overview of the underlying physico-chemical and physical principles of nanoscience.

Metal Ions and Neurodegenerative Disorders

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Publisher : World Scientific
ISBN 13 : 9812383980
Total Pages : 538 pages
Book Rating : 4.8/5 (123 download)

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Book Synopsis Metal Ions and Neurodegenerative Disorders by : Paolo Zatta

Download or read book Metal Ions and Neurodegenerative Disorders written by Paolo Zatta and published by World Scientific. This book was released on 2003 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lipids, proteins, nucleic acids, etc. In addition, several modifications indicative of oxidative stress have been described in association with neurons, neurofibrillary tangles and senile plaques in Alzheimer's disease, including advanced glycation end products and free carbonyl oxidation.Oxidative damage and antioxidant responses are now well characterized, but sources of damaging free radicals are yet to be fully understood. Evidences of alteration in metal ions metabolism have been reported in various diseases like Alzheimer's, Wilson, Menkes, Prion, Pick, Huntington disease, epilepsy and other pathological events. Thus, metal ions play a pivotal role in neurodegenerative phenomena.Chelation therapy is still in the early days of its development, but research in this area could lead to new products that could revolutionize treatment. Two international conferences on ?Metals and the Brain: From Neurochemistry to Neurodegeneration? (Padova, Italy, 2000 and Fez, Morocco, 2002) were recently held to discuss the role of metal ions in neurophysiopathology. A third will be held in 2005 in Johannesburg, South Africa.This book follows the same train of thought as those conferences, in order to highlight the unquestionable importance of metal ions in the research on the neurophysiopathology of neurodegenerative diseases. The excellent reputation of the scientists who have contributed to this project ensures the quality of the chapters presented here, and hopefully this will help spur new research initiatives in the field, which is still in its infancy.

Metal Ions And Neurodengenerative Disorders

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Author :
Publisher : World Scientific
ISBN 13 : 9814485764
Total Pages : 538 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Metal Ions And Neurodengenerative Disorders by : Paolo Zatta

Download or read book Metal Ions And Neurodengenerative Disorders written by Paolo Zatta and published by World Scientific. This book was released on 2003-11-03 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lipids, proteins, nucleic acids, etc. In addition, several modifications indicative of oxidative stress have been described in association with neurons, neurofibrillary tangles and senile plaques in Alzheimer's disease, including advanced glycation end products and free carbonyl oxidation.Oxidative damage and antioxidant responses are now well characterized, but sources of damaging free radicals are yet to be fully understood. Evidences of alteration in metal ions metabolism have been reported in various diseases like Alzheimer's, Wilson, Menkes, Prion, Pick, Huntington disease, epilepsy and other pathological events. Thus, metal ions play a pivotal role in neurodegenerative phenomena.Chelation therapy is still in the early days of its development, but research in this area could lead to new products that could revolutionize treatment. Two international conferences on “Metals and the Brain: From Neurochemistry to Neurodegeneration” (Padova, Italy, 2000 and Fez, Morocco, 2002) were recently held to discuss the role of metal ions in neurophysiopathology. A third will be held in 2005 in Johannesburg, South Africa.This book follows the same train of thought as those conferences, in order to highlight the unquestionable importance of metal ions in the research on the neurophysiopathology of neurodegenerative diseases. The excellent reputation of the scientists who have contributed to this project ensures the quality of the chapters presented here, and hopefully this will help spur new research initiatives in the field, which is still in its infancy.

Copper Proteins and Copper Enzymes

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Author :
Publisher : CRC Press
ISBN 13 : 1351079344
Total Pages : 250 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Copper Proteins and Copper Enzymes by : Rene Lontie

Download or read book Copper Proteins and Copper Enzymes written by Rene Lontie and published by CRC Press. This book was released on 2018-02-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes of Copper Proteins and Copper Enzymes are intended to describe the contemporary spectroscopy and other biophysical chemistry now being applied to copper proteins in order to determine the structures of their active sites. Several chapters of the treatise describe the functional understanding which is emerging from the new work. The authors are all major contributors to research progress on copper proteins and the volumes will be found to be definitive and authoritative.

Metal Metabolism in Animals

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Publisher : MDPI
ISBN 13 : 3038428434
Total Pages : 367 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Metal Metabolism in Animals by : Reinhard Dallinger

Download or read book Metal Metabolism in Animals written by Reinhard Dallinger and published by MDPI. This book was released on 2018-04-20 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Metal Metabolism in Animals" that was published in IJMS

Protein Sensors and Reactive Oxygen Species, Part B: Thiol Enzymes and Proteins

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Author :
Publisher : Elsevier
ISBN 13 : 0080496962
Total Pages : 439 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Protein Sensors and Reactive Oxygen Species, Part B: Thiol Enzymes and Proteins by :

Download or read book Protein Sensors and Reactive Oxygen Species, Part B: Thiol Enzymes and Proteins written by and published by Elsevier. This book was released on 2002-03-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.

Protein Sensors and Reactive Oxygen Species

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Publisher : Academic Press
ISBN 13 : 0121822516
Total Pages : 440 pages
Book Rating : 4.1/5 (218 download)

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Book Synopsis Protein Sensors and Reactive Oxygen Species by : Helmut Sies

Download or read book Protein Sensors and Reactive Oxygen Species written by Helmut Sies and published by Academic Press. This book was released on 2002 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.

Examining the Current State of Cosmetics

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Author :
Publisher :
ISBN 13 :
Total Pages : 540 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Examining the Current State of Cosmetics by : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health

Download or read book Examining the Current State of Cosmetics written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health and published by . This book was released on 2013 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cadmium and Health

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Publisher : CRC Press
ISBN 13 : 042952272X
Total Pages : 320 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Cadmium and Health by : Lars T. Friberg

Download or read book Cadmium and Health written by Lars T. Friberg and published by CRC Press. This book was released on 2019-06-27 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1985: Volume 1: Exposure, Dose and Metabolism, treats analysis of cadmium, its uses and occurrence in the environment, cadmium and metallothionein, normal values in human tissues and fluids, metabolism, and presents a metabolic model for cadmium.

Cancer Drug Resistance

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Publisher : Springer Science & Business Media
ISBN 13 : 1597450359
Total Pages : 611 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Cancer Drug Resistance by : Beverly A. Teicher

Download or read book Cancer Drug Resistance written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2007-11-09 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

Nephrotoxicity in the Experimental and Clinical Situation

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Publisher : Springer Science & Business Media
ISBN 13 : 9400933711
Total Pages : 448 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Nephrotoxicity in the Experimental and Clinical Situation by : P.H. Bach

Download or read book Nephrotoxicity in the Experimental and Clinical Situation written by P.H. Bach and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Inorganic Chemistry

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Publisher : University Science Books
ISBN 13 : 9781891389436
Total Pages : 794 pages
Book Rating : 4.3/5 (894 download)

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Book Synopsis Biological Inorganic Chemistry by : Ivano Bertini

Download or read book Biological Inorganic Chemistry written by Ivano Bertini and published by University Science Books. This book was released on 2007 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Binding, Transport and Storage of Metal Ions in Biological Cells

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782622829
Total Pages : 990 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Binding, Transport and Storage of Metal Ions in Biological Cells by : Wolfgang Maret

Download or read book Binding, Transport and Storage of Metal Ions in Biological Cells written by Wolfgang Maret and published by Royal Society of Chemistry. This book was released on 2014-07-09 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

NMR of Proteins and Small Biomolecules

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Publisher : Springer Science & Business Media
ISBN 13 : 3642289169
Total Pages : 255 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis NMR of Proteins and Small Biomolecules by : Guang Zhu

Download or read book NMR of Proteins and Small Biomolecules written by Guang Zhu and published by Springer Science & Business Media. This book was released on 2012-03-28 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Application of NMR and Molecular Docking in Structure-Based Drug Discovery, by Jaime L. Stark and Robert Powers NMR as a Unique Tool in Assessment and Complex Determination of Weak Protein-Protein Interactions, by Olga Vinogradova and Jun Qin The Use of Residual Dipolar Coupling in Studying Proteins by NMR, by Kang Chen und Nico Tjandra NMR Studies of Metalloproteins, by Hongyan Li and Hongzhe Sun Recent Developments in 15N NMR Relaxation Studies that Probe Protein Backbone Dynamics, by Rieko Ishima Contemporary Methods in Structure Determination of Membrane Proteins by Solution NMR, by Tabussom Qureshi and Natalie K. Goto Protein Structure Determination by Solid-State NMR, by Xin Zhao Dynamic Nuclear Polarization: New Methodology and Applications, by Kong Hung Sze, Qinglin Wu, Ho Sum Tse and Guang Zhu