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Metallothionein In Biology And Medicine
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Book Synopsis Metallothionein in Biology and Medicine by : Curtis D. Klaassen
Download or read book Metallothionein in Biology and Medicine written by Curtis D. Klaassen and published by CRC Press. This book was released on 1991-08-27 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together work from leading researchers to present the most recent advances in research on metallothionein. This protein interests toxicologists because it is thought that metallothionein protects against metal toxicity and possibly against oxidative stress. It is of interest to pharmacologists because modification of metallothionein levels might have a role in cancer chemotherapy. Nutritionists have an interest in this protein because it appears to be a major storage protein for zinc. Biochemists and molecular biologists will be interested in the mechanisms of regulation of this protein because it is extremely inducible.
Download or read book Metallothionein IV written by C. Klaasen and published by Birkhäuser. This book was released on 2012-12-06 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.
Book Synopsis Metallothionein III by : Kazuo T. Suzuki
Download or read book Metallothionein III written by Kazuo T. Suzuki and published by Birkhauser. This book was released on 1993 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metallothioneins in Biochemistry and Pathology by : Paolo Zatta
Download or read book Metallothioneins in Biochemistry and Pathology written by Paolo Zatta and published by World Scientific. This book was released on 2008 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.
Download or read book Metallothionein IV written by C Klaasen and published by . This book was released on 1998-12-01 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metallothionein by : Jeremias H. R. Kägi
Download or read book Metallothionein written by Jeremias H. R. Kägi and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metal Ions in Biology and Medicine by : Philippe Collery
Download or read book Metal Ions in Biology and Medicine written by Philippe Collery and published by John Libbey Eurotext. This book was released on 2000 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of the 6th ISMIBM is to foster exchange of opinions between professionals and specialists working on analysis, research and applications of metal ions, trace elements and minerals in biological, biochemical, medical sciences, toxicology and environmental health. The scientific program, composed of plenary and concurrent sessions, and poster presentations is designed to promote intensive and productive dialogue among experts in these fields. A special program with short courses and mini-symposia have also been organised, featuring specialised areas including toxicology, analysis, pathology, remediation strategies, and environmental medicine. Original contributions (oral and/or poster presentations) are invited on the following themes: Metals and Environmental Health; Molecular Toxicology of Metals; Carcinogenicity of Metals; Speciation of Metals and Other Elements; Uses of Metals in Clinical Applications; Metals and Disease: Environmental and Toxicologic Pathology; Epidemiology and Occupational Health; Metals and Aging; Metals and Homeostasis; Effects of Low and High Nutritional Trace Element Status; Metals and Hormone Actions; Metals and Enzyme Activity; Metals and Chelation Therapy; Health Effects of Arsenic; Risk Assessment of Trace Element Status and Health; Advanced Methods for the Analysis of Trace Elements and Metal Ions.
Book Synopsis Metallothioneins in Normal and Cancer Cells by : Piotr Dziegiel
Download or read book Metallothioneins in Normal and Cancer Cells written by Piotr Dziegiel and published by Springer. This book was released on 2016-02-04 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
Download or read book Metallothionin III written by K.T. Suzuki and published by Birkhäuser. This book was released on 1993-01-01 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the biological roles and medical implications of metallothioneins, and related chemical and biochemical developments. The contributors present and discuss findings on the roles of metallothionein in various kinds of stress conditions, including exposure to heavy metals.
Book Synopsis Selenium in Biology and Medicine by : Albrecht Wendel
Download or read book Selenium in Biology and Medicine written by Albrecht Wendel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: In July, 1988, more than 300 scientists from 29 different countries gathered at Tiibingen, W. Germany, in order to spend 4 days discussing their favourite trace element, selenium. This meeting continued the good tradition of three previous meetings held in Corvallis/Oregon, 1976, in Lubbock/Texas, 1980, and in Beijing/China, in 1984. Incidentally, the University of Tiibingen provided a unique historical background for a Symposium devoted to recent advances in biochemistry, pharmacology, human nutrition and human health; here, the first independent depart ment of Physiological Chemistry in Germany was founded in 1845. Pro fessor H9Ppe-Seyler elucidated here the hemin structure and his student Friedrich Miescher discovered the nucleic acids. This book contains one-half of the oral or poster presentations which were selected before the meeting was held on the basis of a one page abstract. It is the reader who will have to decide whether this time consuming policy of quality assessment was warranted or not.
Book Synopsis Medical Biochemistry by : Antonio Blanco
Download or read book Medical Biochemistry written by Antonio Blanco and published by Academic Press. This book was released on 2022-03-23 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Medical Biochemistry is supported by more than 45 years of teaching experience, providing coverage of basic biochemical topics, including the structural, physical, and chemical properties of water, carbohydrates, lipids, proteins, and nucleic acids. In addition, the general aspects of thermodynamics, enzymes, bioenergetics, and metabolism are presented in straightforward and easy-to-comprehend language. This book ties these concepts into more complex aspects of biochemistry using a systems approach, dedicating chapters to the integral study of biological phenomena, including cell membrane structure and function, gene expression and regulation, protein synthesis and post-translational modifications, metabolism in specific organs and tissues, autophagy, cell receptors, signal transduction pathways, biochemical bases of endocrinology, immunity, vitamins and minerals, and hemostasis. The field of biochemistry is continuing to grow at a fast pace. This edition has been revised and expanded with all-new sections on the cell plasma membrane, the human microbiome, autophagy, noncoding, small and long RNAs, epigenetics, genetic diseases, virology and vaccines, cell signaling, and different modes of programmed cell death. The book has also been updated with full-color figures, new tables, chapter summaries, and further medical examples to improve learning and better illustrate the concepts described and their clinical significance. Integrates basic biochemistry principles with molecular biology and molecular physiology Illustrates basic biochemical concepts through medical and physiological examples Utilizes a systems approach to understanding biological phenomena Fully updated for recent studies and expanded to include clinically relevant examples and succinct chapter summaries
Book Synopsis Zinc Biochemistry, Physiology, and Homeostasis by : W. Maret
Download or read book Zinc Biochemistry, Physiology, and Homeostasis written by W. Maret and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters in this book review the remarkable advances in the field of zinc biology over the last decade. Zinc is essential for life, in particular for growth and development, through its role in hundreds of zinc enzymes and thousands of zinc proteins. Its catalytic, structural, and regulatory functions in these proteins impact metabolism, gene expression, and signal transduction, including neurotransmission. Among the micronutrients, zinc may rank with iron as to its importance for public health. The topics covered range from single molecules to cells and to whole organisms: the chemistry, design, and application of fluorophores for the determination of cellular zinc; the role of zinc in proliferation, differentiation, and apoptosis of cells; proteins that transport, sense, and distribute zinc and together form a cellular homeostatic system; the coordination chemistry of zinc in metalloproteins; the role of zinc in the brain as a neuromodulator/transmitter; the dependence of the immune system on zinc; zinc homeostasis in the whole human body.
Book Synopsis Handbook on the Toxicology of Metals: Specific metals by : Lars Friberg
Download or read book Handbook on the Toxicology of Metals: Specific metals written by Lars Friberg and published by Elsevier Science & Technology. This book was released on 1986 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.
Book Synopsis Metal Ions in Biological Systems by : Helmut Sigel
Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 2023-07-14 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume first considers the categories of zinc metalloenzymes, together with models of the enzymic metal-ion binding sites. It covers the nutritional aspects of zinc: its absorption and excretion, its influence on the activity of enzymes and hormones, and the zinc deficiency syndrome.
Book Synopsis Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc by : Institute of Medicine
Download or read book Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.
Book Synopsis Biological Inorganic Chemistry by : Robert R. Crichton
Download or read book Biological Inorganic Chemistry written by Robert R. Crichton and published by Elsevier. This book was released on 2007-12-11 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters
Book Synopsis Zinc Signals in Cellular Functions and Disorders by : Toshiyuki Fukada
Download or read book Zinc Signals in Cellular Functions and Disorders written by Toshiyuki Fukada and published by Springer. This book was released on 2014-09-25 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the crucial role of "zinc signals" in biological processes on a molecular and physiological basis, discussing future directions and questions underlying this unique phenomenon. To accomplish this, a group of worldwide leaders in the field, who have made outstanding contributions, overview zinc signals from a professional standpoint. Zinc plays an indispensable role in various cellular processes. It regulates a great number of protein functions including transcription factors, enzymes, adapters, and growth factors as a structural or catalytic factor or both. Recently, another function of zinc has received extensive interest and attention because of its potential importance as a signaling mediator. Zinc plays a dynamic role as an intracellular and extracellular signaling factor and thus regulates cellular signaling pathways, which enables communication between cells, conversion of extracellular stimuli to intracellular signals, and control of various intracellular events. These functions of zinc have become recognized as “zinc signals,” which play critical roles in physiology, and therefore their imbalance can cause a variety of problems with regard to human health. Because the notion of zinc signals is quite new and no integrative review books focusing on them have yet been published, we believe this book will provide very timely information on the subject and thus should be of importance and interest to a wide range of readers.
