Metabolomics From Fundamentals To Clinical Applications

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Metabolomics: From Fundamentals to Clinical Applications

Author : Alessandra Sussulini
Publisher : Springer
ISBN 13 : 3319476564
Total Pages : 350 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Metabolomics: From Fundamentals to Clinical Applications by : Alessandra Sussulini

Download or read book Metabolomics: From Fundamentals to Clinical Applications written by Alessandra Sussulini and published by Springer. This book was released on 2017-01-28 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.

Metabolomics

Author : Jeevan Prasain
Publisher : BoD – Books on Demand
ISBN 13 : 9535128531
Total Pages : 218 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Metabolomics by : Jeevan Prasain

Download or read book Metabolomics written by Jeevan Prasain and published by BoD – Books on Demand. This book was released on 2016-12-28 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics: Fundamentals and Applications authoritatively presents the basic principles and applications of metabolomics. Topics covered in this book range from the analysis of metabolites from different biological sources and their data processing and statistical analysis. This book serves as a basic guide for a wide range of audiences from less familiar with metabolomics techniques to more experienced researchers seeking to understand complex biological systems from the systems biology approach.

Metabolomics Â€“ Fundamentals and Applications

Author :
Publisher :
ISBN 13 : 9789535128540
Total Pages : pages
Book Rating : 4.1/5 (285 download)

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Book Synopsis Metabolomics Â€“ Fundamentals and Applications by :

Download or read book Metabolomics Â€“ Fundamentals and Applications written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Capillary Electrophoresis - Mass Spectrometry for Proteomics and Metabolomics

Author : Rawi Ramautar
Publisher : John Wiley & Sons
ISBN 13 : 3527833102
Total Pages : 404 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Capillary Electrophoresis - Mass Spectrometry for Proteomics and Metabolomics by : Rawi Ramautar

Download or read book Capillary Electrophoresis - Mass Spectrometry for Proteomics and Metabolomics written by Rawi Ramautar and published by John Wiley & Sons. This book was released on 2022-10-03 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics A powerful and essential resource for researchers with an interest in CE-MS In Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications, a team of distinguished researchers delivers a comprehensive overview of bioanalytical capillary electrophoresis coupled to mass spectrometry (CE-MS). The book explains foundational principles, technology as well the strategies and techniques used in data analysis for metabolic and proteomic studies. It also provides a global overview of recent developments and advances for improving CE-MS sensitivity and reproducibility. An essential handbook for everyone performing metabolomic and proteomic analysis, the information provided here will assist researchers in tapping into the full potential of this technique to answer biological and clinical questions. Readers will also find: A thorough introduction to the principles of capillary electrophoresis, including its fundamentals, CE separation modes, capillary coatings, and the fundamentals of mass spectrometry In-depth examinations of technological developments in capillary electrophoresis, including sample preparation, online preconcentration, detection sensitivity, and metabolic coverage Comprehensive discussions of metabolomic studies, including their biomedical and clinical applications Recent advances in proteomics, including top-down and bottom-up approaches Perfect for analytical and clinical chemists, Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications will also earn a place in the libraries of biochemists, molecular biologists, and other molecular life scientists.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Chromatographic Methods in Metabolomics

Author : Tuulia Hyotylainen
Publisher : Royal Society of Chemistry
ISBN 13 : 1849737274
Total Pages : 350 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Chromatographic Methods in Metabolomics by : Tuulia Hyotylainen

Download or read book Chromatographic Methods in Metabolomics written by Tuulia Hyotylainen and published by Royal Society of Chemistry. This book was released on 2013-09-06 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of a metabolic profile was introduced in 1971, when gas chromatography demonstrated a range of compounds present in human samples. Now termed metabolomics, the field is still emerging, and chromatography remains an essential tool for determining metabolites in a living system. This is the first book to present the chromatographic techniques used in metabolomics in a fundamental way. Sample preparation and quality control are described in detail, and all forms of chromatography applied to metabolomics are included. The editors present guidelines on selecting the most appropriate methodology, making the book an accessible guide to anyone entering the field. Handling data and applications are also described. This is an essential handbook for any laboratory looking to embark on a metabolomics research programme and includes the fundamentals of chromatography alongside the latest developments in the field.

Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

Author : Joel Faintuch
Publisher : Academic Press
ISBN 13 : 0128152508
Total Pages : 506 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications by : Joel Faintuch

Download or read book Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications written by Joel Faintuch and published by Academic Press. This book was released on 2019-01-03 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike. Provides comprehensive coverage on diagnosis, therapy, pharmacotherapy and disease prevention in context of the microbiome and metabolome Focuses on the proposed physiological or pathological conditions Presents an up-to-date, useful reference

Clinical Metabolomics Applications in Genetic Diseases

Author : Anas M. Abdel Rahman
Publisher : Springer Nature
ISBN 13 : 9819951623
Total Pages : 349 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Clinical Metabolomics Applications in Genetic Diseases by : Anas M. Abdel Rahman

Download or read book Clinical Metabolomics Applications in Genetic Diseases written by Anas M. Abdel Rahman and published by Springer Nature. This book was released on 2023-10-31 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book helps readers discover the forefront of personalized medicine on clinical metabolomics and its applications in genetic diseases. This comprehensive guide offers a functional relationship map between cell components and genetic variations in various diseases, providing insights that can be applied to personalized medicine. The book covers the latest developments in metabolomics for health, with practical guidance for clinical experts looking to advance their laboratory techniques and career. The metabolomics profile is a powerful tool that has revolutionized our understanding of the relationship between genetics, clinical readouts, and disease outcomes. By integrating metabolomics with genomics and clinical phenotypes, the authors have developed diagnostic and prediction models that have vastly improved patient outcomes and deepened the understanding of disease mechanisms. This model has been successfully applied in various conditions, including inborn errors of metabolism, primary immunodeficiency, and endocrine disorders. However, integrating metabolomics with other omics datasets and clinical phenotypes requires careful study design, analytical tools, and data analysis and interpretation. This groundbreaking new book provides essential guidance for researchers, students, and professionals looking to leverage metabolomics in their own work, including biochemical and clinical geneticists, pharmacogenomics and pharmacometabolomics experts, pharmaceutics and diagnostic researchers, medical scientists, clinical dietitians, metabolic engineers, clinical chemists, and personalized medicine specialists.

Metabolomics

Author : Xianquan Zhan
Publisher : BoD – Books on Demand
ISBN 13 : 1839690836
Total Pages : 170 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Metabolomics by : Xianquan Zhan

Download or read book Metabolomics written by Xianquan Zhan and published by BoD – Books on Demand. This book was released on 2021-09-01 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics is the methodology and theory to study the metabolome, including targeted approaches based on selected/multiple reaction monitoring (SRM/MRM) and untargeted approaches based on nuclear magnetic resonance (NMR) or mass spectrometry (MS). The metabolome contains all metabolites derived from sugars, lipids, proteins, and nucleic acids in a given biological system, tissue, cell, or body fluid in a metabolic network system. Metabolomic variations directly link to molecular mechanisms of a disease, reliable therapeutic targets, and effective biomarkers for prediction, diagnosis, and prognostic assessment of disease. This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.

Single-Cell Omics

Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 012817532X
Total Pages : 384 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Single-Cell Omics by : Debmalya Barh

Download or read book Single-Cell Omics written by Debmalya Barh and published by Academic Press. This book was released on 2019-07-31 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis. Covers the diverse single cell omics applications in the biomedical field Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis Written by experts across the world, it brings different points-of-view and study cases to fully give a comprehensive overview of the topic

Metabolomics

Author : Vijay Soni
Publisher : Springer Nature
ISBN 13 : 3031390946
Total Pages : 527 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Metabolomics by : Vijay Soni

Download or read book Metabolomics written by Vijay Soni and published by Springer Nature. This book was released on 2023-10-24 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book Introduces the extensive applications of metabolomics from all possible areas of research and development so that not only an undergraduate can understand the advancement of metabolomics, but an entrepreneur can harness the knowledge to address possible problems to make a perfect tool to address their research question. Topics covered include the role of metabolomics in the development of agriculture, plant pathology, and their applications; the generalized application of the metabolomics and use of related technologies in various sectors of industries; and the future of metabolomics and upcoming related technologies that can fill the gap between different -omics and their applications for the betterment of humankind. This is an ideal book for university professors, researchers, and advanced-level scientists who are exploring different avenues in metabolomics. Availability of this concise information in one place will aid scientists by expanding their arsenal of techniques and can be helpful to bring more collaborations and to identify the expert at the global level.

Global metabolic profiling clinical applications

Author : Georgios Theodoridis
Publisher :
ISBN 13 : 9781909453609
Total Pages : 192 pages
Book Rating : 4.4/5 (536 download)

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Book Synopsis Global metabolic profiling clinical applications by : Georgios Theodoridis

Download or read book Global metabolic profiling clinical applications written by Georgios Theodoridis and published by . This book was released on 2014 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MALDI Mass Spectrometry Imaging

Author : Tiffany Siegel Porta
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162414
Total Pages : 541 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis MALDI Mass Spectrometry Imaging by : Tiffany Siegel Porta

Download or read book MALDI Mass Spectrometry Imaging written by Tiffany Siegel Porta and published by Royal Society of Chemistry. This book was released on 2021-12-03 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

Applications of NMR Spectroscopy

Author : Atta-ur- Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1681084392
Total Pages : 238 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Applications of NMR Spectroscopy by : Atta-ur- Rahman

Download or read book Applications of NMR Spectroscopy written by Atta-ur- Rahman and published by Bentham Science Publishers. This book was released on 2017-12-04 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The sixth volume of the series features reviews focusing on NMR spectroscopic techniques for studying tautomerism, applications in medical diagnosis, in food chemistry and identifying secondary metabolites.

Environmental Metabolomics

Author : Diana Alvarez-Munoz
Publisher : Elsevier
ISBN 13 : 0128181974
Total Pages : 368 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Environmental Metabolomics by : Diana Alvarez-Munoz

Download or read book Environmental Metabolomics written by Diana Alvarez-Munoz and published by Elsevier. This book was released on 2020-05-19 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Metabolomics Applications in Field and Laboratory Studies: From the Exposome to the Metabolome presents an overview of the current state of aquatic environments and problems caused by human pressure and daily life. The presence of contaminants in nature and their effects are evaluated, along with recommendations for preservation. This book not only shows readers how to implement techniques, it also guides them through the process. As metabolomics becomes a more routine technique for environmental studies and future perspectives, a guide for validation and globalization of current approaches is needed. Presents relevant and reliable information on the use of different analytical techniques for establishing the environmental metabolomics of polluted systems Includes a critical review of each central topic in every chapter, together with a bibliography and future trends Provides, for the first time, a global opinion and guide for achieving standardized results

Metabolomics Perspectives

Author : Jacopo Troisi
Publisher : Academic Press
ISBN 13 : 0323850634
Total Pages : 685 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Metabolomics Perspectives by : Jacopo Troisi

Download or read book Metabolomics Perspectives written by Jacopo Troisi and published by Academic Press. This book was released on 2022-03-15 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics Perspectives: From Theory to Practical Application is an expertly written volume, which provides a thorough description of the current state-of-the-art in the metabolomics field. The philosophy behind the book is to guide the reader in a step-by-step exploration of metabolomics experiments, ranging from sample preparation to data extraction, analysis and interpretation, and to discuss the main current applications and future perspectives of this emerging science. Armed with critical insights, coupled with a clear writing, the book consists of three main sections. The first one introduces the pivotal theoretical fundamentals and provides a comprehensive overview of the "wet" laboratory workflow, including protocol instructions and a detailed description of experimental methods and analytical techniques. The second section covers a wide range of topics in the context of data analysis, including guidance in exploratory analysis, supervised and unsupervised machine learning approaches and validation and optimization methods. In addition to the several examples reported in the text, the book features an R package, specifically designed to perform all the described algorithms, which is hosted on a companion website (www.metabolomicsperspectives.com) together with several sets of available metabolomic data. Finally, an extensive dissertation describes the latest advances and the major fields of interest for metabolomics applications, highlighting their crucial potentials for future biomedical research. Thus, this book represents a must-read for both experienced researchers, interested in metabolomics, and newcomers to the field. Provides an in-depth description of the metabolomics experimental workflow and its applications in life science and biomedical research Features chapter contributions from the greatest international experts in the field Includes an R package and several sets of metabolomics data, hosted on a companion website

Microbial Metabolomics

Author : David J. Beale
Publisher : Springer
ISBN 13 : 3319463268
Total Pages : 321 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Microbial Metabolomics by : David J. Beale

Download or read book Microbial Metabolomics written by David J. Beale and published by Springer. This book was released on 2016-12-05 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together contributions from global experts who have helped to facilitate the exciting and rapid advances that are taking place in microbial metabolomics. The main application of this field is in clinical and veterinary microbiology, but there is a great potential to apply metabolomics to help to better understand complex biological systems that are dominated by multiple-species microbial populations exposed to changing growth and nutritional conditions. In particular, environmental (e.g., water, soil), food (e.g., microbial spoilage, food pathogens), and agricultural and industrial applications are seen as developing areas for microbial metabolomics. As such, the book includes contributions with clinical, environmental, and industrial perspectives.