The Handbook of Metabonomics and Metabolomics

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Publisher : Elsevier
ISBN 13 : 0080468004
Total Pages : 573 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Handbook of Metabonomics and Metabolomics by : John C. Lindon

Download or read book The Handbook of Metabonomics and Metabolomics written by John C. Lindon and published by Elsevier. This book was released on 2011-08-11 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. * comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Metabolomics: From Fundamentals to Clinical Applications

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Publisher : Springer
ISBN 13 : 3319476564
Total Pages : 350 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Metabolomics: From Fundamentals to Clinical Applications by : Alessandra Sussulini

Download or read book Metabolomics: From Fundamentals to Clinical Applications written by Alessandra Sussulini and published by Springer. This book was released on 2017-01-28 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.

Computational Methods and Data Analysis for Metabolomics

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Publisher : Humana
ISBN 13 : 9781071602416
Total Pages : 491 pages
Book Rating : 4.6/5 (24 download)

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Book Synopsis Computational Methods and Data Analysis for Metabolomics by : Shuzhao Li

Download or read book Computational Methods and Data Analysis for Metabolomics written by Shuzhao Li and published by Humana. This book was released on 2021-02-01 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive guide to scientists, engineers, and students that employ metabolomics in their work, with an emphasis on the understanding and interpretation of the data. Chapters guide readers through common tools for data processing, using database resources, major techniques in data analysis, and integration with other data types and specific scientific domains. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, practical guidance of methods and techniques, useful web supplements, and connect the steps from experimental metabolomics to scientific discoveries. Authoritative and cutting-edge, Computational Methods and Data Analysis for Metabolomics to ensure successful results in the further study of this vital field.

Metabolomics

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Publisher : Humana
ISBN 13 : 9781071608630
Total Pages : 0 pages
Book Rating : 4.6/5 (86 download)

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Book Synopsis Metabolomics by : Paul L. Wood

Download or read book Metabolomics written by Paul L. Wood and published by Humana. This book was released on 2020-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses the latest analytical approaches used to sample defined molecular populations of metabolites via functional group derivatization, specialized chromatographic methods, and ionization techniques. Chapters cover key methods for sample introductions to the ion source, including direct flow, gas chromatography, liquid chromatography, and capillary electrophoresis. Chapters also explore non-targeted and targeted analyses, as well as the emerging field of metallomics. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Metabolomics is a valuable resource for students, researchers, practicing physicians and veterinarians, and administrators involved in the funding of research.

Plant Metabolomics

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Publisher : Springer Science & Business Media
ISBN 13 : 3540297820
Total Pages : 351 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Plant Metabolomics by : Kazuki Saito

Download or read book Plant Metabolomics written by Kazuki Saito and published by Springer Science & Business Media. This book was released on 2006-06-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.

Metabolomics, Metabonomics and Metabolite Profiling

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Publisher : Royal Society of Chemistry
ISBN 13 : 0854042997
Total Pages : 336 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Metabolomics, Metabonomics and Metabolite Profiling by : William J. Griffiths

Download or read book Metabolomics, Metabonomics and Metabolite Profiling written by William J. Griffiths and published by Royal Society of Chemistry. This book was released on 2008 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive resource the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology.

Microbial Metabolomics

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Publisher : Springer
ISBN 13 : 3319463268
Total Pages : 321 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Microbial Metabolomics by : David J. Beale

Download or read book Microbial Metabolomics written by David J. Beale and published by Springer. This book was released on 2016-12-05 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together contributions from global experts who have helped to facilitate the exciting and rapid advances that are taking place in microbial metabolomics. The main application of this field is in clinical and veterinary microbiology, but there is a great potential to apply metabolomics to help to better understand complex biological systems that are dominated by multiple-species microbial populations exposed to changing growth and nutritional conditions. In particular, environmental (e.g., water, soil), food (e.g., microbial spoilage, food pathogens), and agricultural and industrial applications are seen as developing areas for microbial metabolomics. As such, the book includes contributions with clinical, environmental, and industrial perspectives.

Mass Spectrometry-Based Metabolomics

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Publisher : CRC Press
ISBN 13 : 1482223775
Total Pages : 294 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Mass Spectrometry-Based Metabolomics by : Sastia Prama Putri

Download or read book Mass Spectrometry-Based Metabolomics written by Sastia Prama Putri and published by CRC Press. This book was released on 2016-04-21 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry-Based Metabolomics: A Practical Guide is a simple, step-by-step reference for profiling metabolites in a target organism. It discusses optimization of sample preparation for urine, serum, blood, tissue, food, and plant and animal cell samples. Encompassing three different technical fields—biology, analytical chemistry, and informatics— mass spectrometry-based metabolomics can be challenging for biologists without special training in quantitative mass spectrometry. This book is designed to overcome this limitation by providing researchers with the knowledge they need to use metabolomics technology in their respective disciplines. The book summarizes all steps in metabolomics research, from experimental design to sample preparation, analytical procedures, and data analysis. Case studies are presented for easy understanding of the metabolomics workflow and its practical applications in different research fields. The book includes an in-house library and built-in software so that those new to the field can begin to analyze real data samples. In addition to being an excellent introductory text, the book also contains the latest advancements in this emerging field and can thus be a useful reference for metabolomics specialists.

Metabolomics in Food and Nutrition

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Publisher : Elsevier
ISBN 13 : 0857098810
Total Pages : 264 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Metabolomics in Food and Nutrition by : Bart C Weimer

Download or read book Metabolomics in Food and Nutrition written by Bart C Weimer and published by Elsevier. This book was released on 2013-10-31 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry. Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes. With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area. Provides an overview of the current and potential future use of metabolomics in the food industry Chapters focus on key applications and review the analytical methods used and the bioinformatics techniques involved in processing the results Discusses metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications

Metabolomics

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Publisher : CRC Press
ISBN 13 : 1315353482
Total Pages : 313 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Metabolomics by : Ron Wehrens

Download or read book Metabolomics written by Ron Wehrens and published by CRC Press. This book was released on 2019-08-19 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics is the scientific study of the chemical processes in a living system, environment and nutrition. It is a relatively new omics science, but the potential applications are wide, including medicine, personalized medicine and intervention studies, food and nutrition, plants, agriculture and environmental science. The topics presented and discussed in this book are based on the European Molecular Biology Organization (EMBO) practical courses in metabolomics bioinformatics taught to those working in the field, from masters to postgraduate students, PhDs, postdoctoral and early PIs. The book covers the basics and fundamentals of data acquisition and analytical technologies, but the primary focus is data handling and data analysis. The mentioning and usage of a particular data analysis tool has been avoided; rather, the focus is on the concepts and principles of data processing and analysis. The material has been class-tested and includes lots of examples, computing and exercises. Key Features: Provides an overview of qualitative /quantitative methods in metabolomics Offers an introduction to the key concepts of metabolomics, including experimental design and technology Covers data handling, processing, analysis, data standards and sharing Contains lots of examples to illustrate the topics Includes contributions from some of the leading researchers in the field of metabolomics with extensive teaching experiences

Metabolomics Data Processing and Data Analysis-Current Best Practices

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Publisher : Mdpi AG
ISBN 13 : 9783036511948
Total Pages : 276 pages
Book Rating : 4.5/5 (119 download)

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Book Synopsis Metabolomics Data Processing and Data Analysis-Current Best Practices by : Justin Van Der Hooft

Download or read book Metabolomics Data Processing and Data Analysis-Current Best Practices written by Justin Van Der Hooft and published by Mdpi AG. This book was released on 2021-09-10 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics data analysis strategies are central to transforming raw metabolomics data files into meaningful biochemical interpretations that answer biological questions or generate novel hypotheses. This book contains a variety of papers from a Special Issue around the theme "Best Practices in Metabolomics Data Analysis". Reviews and strategies for the whole metabolomics pipeline are included, whereas key areas such as metabolite annotation and identification, compound and spectral databases and repositories, and statistical analysis are highlighted in various papers. Altogether, this book contains valuable information for researchers just starting in their metabolomics career as well as those that are more experienced and look for additional knowledge and best practice to complement key parts of their metabolomics workflows.

Proteomic and Metabolomic Approaches to Biomarker Discovery

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Publisher : Academic Press
ISBN 13 : 0128197889
Total Pages : 504 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Proteomic and Metabolomic Approaches to Biomarker Discovery by : Haleem J. Issaq

Download or read book Proteomic and Metabolomic Approaches to Biomarker Discovery written by Haleem J. Issaq and published by Academic Press. This book was released on 2019-10-24 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research. Addresses the full range of proteomic and metabolomic methods and technologies used for biomarker discovery and validation Covers all steps involved in biomarker discovery, from study design to study execution Serves as a vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals and graduate students

NMR-Based Metabolomics

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Publisher : Humana
ISBN 13 : 9781493996926
Total Pages : 489 pages
Book Rating : 4.9/5 (969 download)

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Book Synopsis NMR-Based Metabolomics by : G. A. Nagana Gowda

Download or read book NMR-Based Metabolomics written by G. A. Nagana Gowda and published by Humana. This book was released on 2020-08-29 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics.

Cancer Metabolomics

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Publisher : Springer Nature
ISBN 13 : 3030516520
Total Pages : 317 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Cancer Metabolomics by : Shen Hu

Download or read book Cancer Metabolomics written by Shen Hu and published by Springer Nature. This book was released on 2021-04-01 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling liquid chromatography - mass spectrometry, capillary ion chromatography - mass spectrometry, 2-D gas chromatography – mass spectrometry, capillary electrophoresis – mass spectrometry, nuclear magnetic resonance spectroscopy, shotgun lipidomics, tracer-based metabolomics, microbial metabolomics, mass spectrometry imaging for single cell metabolomics and functional metabolomics. In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translational applications of metabolomics in human cancers such as glioma, head and neck cancer, and gastric cancer. This new volume will be a unique reference source for cancer researchers and promote applications of metabolomics in understanding cancer metabolism.

Metabolomics

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Publisher : Springer Science & Business Media
ISBN 13 : 1597452440
Total Pages : 290 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Metabolomics by : Wolfram Weckwerth

Download or read book Metabolomics written by Wolfram Weckwerth and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.

NMR Metabolomics in Cancer Research

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Publisher : Elsevier
ISBN 13 : 1908818263
Total Pages : 446 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis NMR Metabolomics in Cancer Research by : Miroslava Čuperlović-Culf

Download or read book NMR Metabolomics in Cancer Research written by Miroslava Čuperlović-Culf and published by Elsevier. This book was released on 2012-12-17 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Ecometabolomics

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Publisher : Academic Press
ISBN 13 : 012814873X
Total Pages : 401 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Ecometabolomics by : Sumira Jan

Download or read book Ecometabolomics written by Sumira Jan and published by Academic Press. This book was released on 2019-03-10 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics. Provides an in-depth overview of the basics of the discipline, including non-targeted analysis and quantification of plant metabolites Outlines the applications of various analytical techniques in comprehending the total metabolome of the organism Covers both NMR and MS-based approaches