Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 0128205512
Total Pages : 232 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases by :

Download or read book Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases written by and published by Academic Press. This book was released on 2019-10-25 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Annual Reports in Medicinal Chemistry series Includes the latest information on Medicinal Approaches to Malaria and Other Tropical Diseases

Disease Control Priorities, Third Edition (Volume 6)

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Author :
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Saving Lives, Buying Time

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Author :
Publisher : National Academies Press
ISBN 13 : 0309165938
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Saving Lives, Buying Time by : Institute of Medicine

Download or read book Saving Lives, Buying Time written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-09 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

CDC Yellow Book 2018: Health Information for International Travel

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Author :
Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 705 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Malaria

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Publisher : National Academies Press
ISBN 13 : 9780309045278
Total Pages : 312 pages
Book Rating : 4.0/5 (452 download)

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Book Synopsis Malaria by : Institute of Medicine

Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Medicinal Approaches to Malaria and Other Tropical Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 0128175567
Total Pages : 188 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Medicinal Approaches to Malaria and Other Tropical Diseases by : Rui Moreira

Download or read book Medicinal Approaches to Malaria and Other Tropical Diseases written by Rui Moreira and published by Academic Press. This book was released on 2019-09-13 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated. Provides an overview of the status of some of the current novel compounds in development as well as new emerging treatment options targeting novel mechanisms of action Identification of hits from phenotypic whole cell screening, followed by target identification Strategies aimed at improving the efficacy of existing clinically used anti-TB drugs by taking advantage inhibitors of mycobacterial transcriptional regulators to boost the anti-tubercular activity, and circumvent acquired-resistance

The Making of a Tropical Disease

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Publisher : JHU Press
ISBN 13 : 1421441799
Total Pages : 351 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis The Making of a Tropical Disease by : Randall M. Packard

Download or read book The Making of a Tropical Disease written by Randall M. Packard and published by JHU Press. This book was released on 2021-07-13 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: A global history of malaria that traces the natural and social forces that have shaped its spread and made it deadly, while limiting efforts to eliminate it. Malaria sickens hundreds of millions of people—and kills nearly a half a million—each year. Despite massive efforts to eradicate the disease, it remains a major public health problem in poorer tropical regions. But malaria has not always been concentrated in tropical areas. How did malaria disappear from other regions, and why does it persist in the tropics? From Russia to Bengal to Palm Beach, Randall M. Packard's far-ranging narrative shows how the history of malaria has been driven by the interplay of social, biological, economic, and environmental forces. The shifting alignment of these forces has largely determined the social and geographical distribution of the disease, including its initial global expansion, its subsequent retreat to the tropics, and its current persistence. Packard argues that efforts to control and eliminate malaria have often ignored this reality, relying on the use of biotechnologies to fight the disease. Failure to address the forces driving malaria transmission have undermined past control efforts. Describing major changes in both the epidemiology of malaria and efforts to control the disease, the revised edition of this acclaimed history, which was chosen as the 2008 End Malaria Awards Book of the Year in its original printing, • examines recent efforts to eradicate malaria following massive increases in funding and political commitment; • discusses the development of new malaria-fighting biotechnologies, including long-lasting insecticide-treated nets, rapid diagnostic tests, combination artemisinin therapies, and genetically modified mosquitoes; • explores the efficacy of newly developed vaccines; and • explains why eliminating malaria will also require addressing the social forces that drive the disease and building health infrastructures that can identify and treat the last cases of malaria. Authoritative, fascinating, and eye-opening, this short history of malaria concludes with policy recommendations for improving control strategies and saving lives.

Malaria

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Author :
Publisher : World Health Organization
ISBN 13 : 9241544910
Total Pages : 37 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Malaria by :

Download or read book Malaria written by and published by World Health Organization. This book was released on 1996-12 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the many simple things that community health workers can do to treat malaria prevent new cases and thus help reduce the alarming number of deaths particularly in young children and pregnant women. Practical in its approach the manual concentrates on activities that are within the competence of health workers and feasible and affordable at the community level. Information ranges from a basic explanation of the disease and its transmission to tables illustrating correct treatment schedules for different age groups. The manual which is abundantly illustrated can be used in training courses as a support to the health worker's day-to-day activities or as a tool for health education in the community. The main purpose is to communicate basic facts and messages that if widely understood within a community could do much to reduce the incidence and severity of malaria. Chloroquine is presented as the first-line treatment. The manual has three parts. The first explains what community health workers can do to control malaria and lists the essential medicines and equipment needed. Part two introduces basic facts about malaria and the behaviour of mosquitos and elaborates three main approaches to malaria prevention in communities. The third and most extensive part sets out step-by-step instructions for the recognition and treatment of malaria giving particular attention to standard malaria treatment schedules measures for ensuring compliance what to do when standard treatment fails and how to recognize treat and refer severe cases. The management of malaria in young children and pregnant women also receives special attention.

Neglected Tropical Diseases - Latin America and the Caribbean

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Author :
Publisher : Springer
ISBN 13 : 3709114225
Total Pages : 247 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Neglected Tropical Diseases - Latin America and the Caribbean by : Carlos Franco-Paredes

Download or read book Neglected Tropical Diseases - Latin America and the Caribbean written by Carlos Franco-Paredes and published by Springer. This book was released on 2015-05-08 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the major neglected tropical diseases (NTDs) – based on their prevalence and the years of healthy life lost to disability – in Latin American and Caribbean countries. These include Chagas disease, leishmaniasis, hookworm infection, and other soil-transmitted helminth infections, followed by dengue, schistosomiasis, leishmaniasis, leprosy, cysticercosis, bartonellosis, Plasmodium vivax malaria, and onchocerciasis. Topics like disease burden, major manifestations and approaches to the control and elimination of NTDs in Latin America and the Caribbean are discussed in detail. As such, the book will be of general interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of this region of the world.​

Global Technical Strategy for Malaria 2016-2030

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Author :
Publisher : World Health Organization
ISBN 13 : 9241564997
Total Pages : 35 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Global Technical Strategy for Malaria 2016-2030 by : World Health Organization

Download or read book Global Technical Strategy for Malaria 2016-2030 written by World Health Organization and published by World Health Organization. This book was released on 2015-11-04 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization's Global Technical Strategy for Malaria 2016- 2030 has been developed with the aim to help countries to reduce the human suffering caused by the world's deadliest mosquito-borne disease. Adopted by the World Health Assembly in May 2015 it provides comprehensive technical guidance to countries and development partners for the next 15 years emphasizing the importance of scaling up malaria responses and moving towards elimination. It also highlights the urgent need to increase investments across all interventions - including preventive measures diagnostic testing treatment and disease surveillance- as well as in harnessing innovation and expanding research. By adopting this strategy WHO Member States have endorsed the bold vision of a world free of malaria and set the ambitious new target of reducing the global malaria burden by 90% by 2030. They also agreed to strengthen health systems address emerging multi-drug and insecticide resistance and intensify national cross-border and regional efforts to scale up malaria responses to protect everyone at risk.

Malaria Methods and Protocols

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592592716
Total Pages : 606 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Malaria Methods and Protocols by : Denise L. Doolan

Download or read book Malaria Methods and Protocols written by Denise L. Doolan and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Plasmodium spp. parasite was identified as the causative agent of malaria in 1880, and the mosquito was identified as the vector in 1897. Despite subsequent efforts focused on the epidemiology, cell biology, immunology, molecular biology, and clinical manifestations of malaria and the Plasmodium parasite, there is still no licensed vaccine for the prevention of malaria. Physical barriers (bed nets, window screens) and chemical prevention methods (insecticides and mosquito repellents) intended to interfere with the transmission of the disease are not highly effective, and the profile of resistance of the parasite to chemoprophylactic and chemotherapeutic agents is increasing. The dawn of the new millennium has seen a resurgence of interest in the disease by government and philanthropic organizations, but we are still faced with compl- ities of the parasite, the host, and the vector, and the interactions among them. Malaria Methods and Protocols offers a comprehensive collection of protocols describing conventional and state-of-the-art techniques for the study of malaria, as well as associated theory and potential problems, written by experts in the field. The major themes reflected here include assessing the risk of infection and severity of disease, laboratory models, diagnosis and typing, molecular biology techniques, immunological techniques, cell biology techniques, and field applications.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

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Author :
Publisher : World Health Organization
ISBN 13 : 9241564865
Total Pages : 211 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Investing to Overcome the Global Impact of Neglected Tropical Diseases by : World Health Organization

Download or read book Investing to Overcome the Global Impact of Neglected Tropical Diseases written by World Health Organization and published by World Health Organization. This book was released on 2015-08-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

CDC Yellow Book 2020

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0190065974
Total Pages : 721 pages
Book Rating : 4.1/5 (9 download)

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Book Synopsis CDC Yellow Book 2020 by : CENTERS FOR DISEASE CONTROL AND PREVENTION. (CDC)

Download or read book CDC Yellow Book 2020 written by CENTERS FOR DISEASE CONTROL AND PREVENTION. (CDC) and published by Oxford University Press, USA. This book was released on 2019-06-11 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference for travel medicine, updated for 2020! "A beloved travel must-have for the intrepid wanderer." -Publishers Weekly "A truly excellent and comprehensive resource." -Journal of Hospital Infection The CDC Yellow Book offers everything travelers and healthcare providers need to know for safe and healthy travel abroad. This 2020 edition includes: · Country-specific risk guidelines for yellow fever and malaria, including expert recommendations and 26 detailed, country-level maps · Detailed maps showing distribution of travel-related illnesses, including dengue, Japanese encephalitis, meningococcal meningitis, and schistosomiasis · Guidelines for self-treating common travel conditions, including altitude illness, jet lag, motion sickness, and travelers' diarrhea · Expert guidance on food and drink precautions to avoid illness, plus water-disinfection techniques for travel to remote destinations · Specialized guidelines for non-leisure travelers, study abroad, work-related travel, and travel to mass gatherings · Advice on medical tourism, complementary and integrative health approaches, and counterfeit drugs · Updated guidance for pre-travel consultations · Advice for obtaining healthcare abroad, including guidance on different types of travel insurance · Health insights around 15 popular tourist destinations and itineraries · Recommendations for traveling with infants and children · Advising travelers with specific needs, including those with chronic medical conditions or weakened immune systems, health care workers, humanitarian aid workers, long-term travelers and expatriates, and last-minute travelers · Considerations for newly arrived adoptees, immigrants, and refugees Long the most trusted book of its kind, the CDC Yellow Book is an essential resource in an ever-changing field -- and an ever-changing world.

Disease Control Priorities, Third Edition (Volume 8)

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Author :
Publisher : World Bank Publications
ISBN 13 : 1464804397
Total Pages : 977 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 8) by : Donald A. P. Bundy

Download or read book Disease Control Priorities, Third Edition (Volume 8) written by Donald A. P. Bundy and published by World Bank Publications. This book was released on 2017-11-20 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.

Partnerships for Malaria Control

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Author :
Publisher : World Health Organization
ISBN 13 : 9241563346
Total Pages : 97 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Partnerships for Malaria Control by : Nicole Fraser

Download or read book Partnerships for Malaria Control written by Nicole Fraser and published by World Health Organization. This book was released on 2006 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication discusses key strategic options for private sector engagement to scale up malaria prevention and treatment, based on current best practice and drawing on experiences in Sub-Saharan Africa and Asia. It seeks to provide practical evidence-based guidance which can be adapted to a variety of country contexts; and it advocates implementation research and illustrates how different options lead into country specific implementation research studies.

Disease in the History of Modern Latin America

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Author :
Publisher : Duke University Press
ISBN 13 : 0822384345
Total Pages : 336 pages
Book Rating : 4.8/5 (223 download)

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Book Synopsis Disease in the History of Modern Latin America by : Diego Armus

Download or read book Disease in the History of Modern Latin America written by Diego Armus and published by Duke University Press. This book was released on 2003-03-26 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Challenging traditional approaches to medical history, Disease in the History of Modern Latin America advances understandings of disease as a social and cultural construction in Latin America. This innovative collection provides a vivid look at the latest research in the cultural history of medicine through insightful essays about how disease—whether it be cholera or aids, leprosy or mental illness—was experienced and managed in different Latin American countries and regions, at different times from the late nineteenth century to the present. Based on the idea that the meanings of sickness—and health—are contestable and subject to controversy, Disease in the History of Modern Latin America displays the richness of an interdisciplinary approach to social and cultural history. Examining diseases in Mexico, Brazil, Argentina, Colombia, Peru, and Bolivia, the contributors explore the production of scientific knowledge, literary metaphors for illness, domestic public health efforts, and initiatives shaped by the agendas of international agencies. They also analyze the connections between ideas of sexuality, disease, nation, and modernity; the instrumental role of certain illnesses in state-building processes; welfare efforts sponsored by the state and led by the medical professions; and the boundaries between individual and state responsibilities regarding sickness and health. Diego Armus’s introduction contextualizes the essays within the history of medicine, the history of public health, and the sociocultural history of disease. Contributors. Diego Armus, Anne-Emanuelle Birn, Kathleen Elaine Bliss, Ann S. Blum, Marilia Coutinho, Marcus Cueto, Patrick Larvie, Gabriela Nouzeilles, Diana Obregón, Nancy Lays Stepan, Ann Zulawski

Malaria

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Author :
Publisher : Wiley
ISBN 13 : 9780471931003
Total Pages : 0 pages
Book Rating : 4.9/5 (31 download)

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Book Synopsis Malaria by : G. A. T. Targett

Download or read book Malaria written by G. A. T. Targett and published by Wiley. This book was released on 1992-04-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria affects very large populations in tropical and sub-tropical areas of the world and the situation is now exacerbated by a growing resistance to drugs and insecticides by parasite and mosquito, respectively. Addresses the problem of public health management at the individual and community level, including the use and supply of drugs currently available as well as the economics of already strained health programs. The current status of vaccine development is assessed and recommendations are made for future research.