Mechanisms Of Fibre Carcinogenesis

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Mechanisms in Fibre Carcinogenesis

Author : Robert C. Brown
Publisher : Springer Science & Business Media
ISBN 13 : 1468413635
Total Pages : 564 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Mechanisms in Fibre Carcinogenesis by : Robert C. Brown

Download or read book Mechanisms in Fibre Carcinogenesis written by Robert C. Brown and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Editors are sorry that the production of this volume was delayed by the ill health of one of them and we hope that this does not detract from the value of the con tents. For once this delay is not the fault of any of the authors only the editors are to blame. Many of the workers in the field of fibre toxicology became convinced by the middle 1980's that the worst of the furore over asbestos was over although we were left with an intriguing problem - how does asbestos cause disease? It was expected that the future impact of fibres on human health would be very small since asbestos exposure would be controlled and there was little chance that man-made fibres would prove haz ardous. These man-made fibres are much thicker than asbestos and, in most cases, they are less durable in the body. Both of these properties are believed to make them much less likely to cause disease. However many of us had fallen into the habit of calling these materials "asbestos substitutes" and thus they have acquired a little of the notoriety at tached to the natural fibrous minerals. Very few of these man-made fibres are actually used as replacements for asbestos. Asbestos was not suitable for the uses to which the insulation wools are usually put and the ceramic fibres are replacements for fire brick not asbestos which is destroyed at the temperatures at which these materials are used.

Mechanisms of Fibre Carcinogenesis

Author : A. B. Kane
Publisher :
ISBN 13 :
Total Pages : 164 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Mechanisms of Fibre Carcinogenesis by : A. B. Kane

Download or read book Mechanisms of Fibre Carcinogenesis written by A. B. Kane and published by . This book was released on 1996 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The result of a meeting held at IARC early in 1996, this volume provides a thorough and up-to-date synthesis of the mechanisms of fibre carcinogenesis. A consensus document assesses the strengths, weaknesses and gaps in the data concerning fibre characterization and genotoxicity, fibre-related cell proliferation and activation, gene expression, animal models, mixed dust exposure and interactions with other carcinogens. The relevance of mechanistic data from in vitro and in vivo assays to the evaluation of fibre carcinogenicity are also discussed. Authored review papers, also published in this volume, provide the background material for much of the discussion.

Mechanisms of Carcinogenesis

Author : Patricia A. Buffler
Publisher : IARC Scientific Publications
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Patricia A. Buffler

Download or read book Mechanisms of Carcinogenesis written by Patricia A. Buffler and published by IARC Scientific Publications. This book was released on 2004 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, molecular epidemiology has become an important discipline in cancer research. It has evolved towards the development, validation and application of markers of susceptibility and, more recently, markers of mechanisms of cancer development. This volume on mechanisms of carcinogenesis covers from an interdisciplinary perspective, the contribution of molecular epidemiology to the understanding of mechanisms of carcinogenesis, and represents a further contribution to the development of molecular epidemiology as a major cancer research domain.

Antimutagenesis and Anticarcinogenesis Mechanisms III

Author : Giorgio Bronzetti
Publisher : Springer
ISBN 13 : 9781461362999
Total Pages : 0 pages
Book Rating : 4.3/5 (629 download)

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Book Synopsis Antimutagenesis and Anticarcinogenesis Mechanisms III by : Giorgio Bronzetti

Download or read book Antimutagenesis and Anticarcinogenesis Mechanisms III written by Giorgio Bronzetti and published by Springer. This book was released on 2012-11-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk area, and vice versa (25,42). Populations that customarily consume fruits and vegetables and also whole grain cereal products generally have a lower risk of cardiovascular diseases and specific types of cancer than populations with a lower intake of such foods, everything else being equal (63). In the last few years, research has provided mechanistic explanations as to the reasons for the protective effects of specific foods. This paper will emphasize the mechanisms whereby cancer risks are reduced by dietary modification.

Mechanisms of Fibre Carcinogenesis

Author : A. B. Kane
Publisher : International Agency for Research on Cancer (I A R C)
ISBN 13 : 9789283221401
Total Pages : 166 pages
Book Rating : 4.2/5 (214 download)

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Book Synopsis Mechanisms of Fibre Carcinogenesis by : A. B. Kane

Download or read book Mechanisms of Fibre Carcinogenesis written by A. B. Kane and published by International Agency for Research on Cancer (I A R C). This book was released on 1996 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The result of a meeting held at IARC early in 1996, this volume provides a thorough and up-to-date synthesis of the mechanisms of fibre carcinogenesis. A consensus document assesses the strengths, weaknesses and gaps in the data concerning fibre characterization and genotoxicity, fibre-related cell proliferation and activation, gene expression, animal models, mixed dust exposure and interactions with other carcinogens. The relevance of mechanistic data fromin vitroandin vivoassays to the evaluation of fibre carcinogenicity are also discussed. Authored review papers, also published in this volume, provide the background material for much of the discussion.

Man-made Vitreous Fibres

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher : World Health Organization
ISBN 13 : 9283212819
Total Pages : 434 pages
Book Rating : 4.2/5 (832 download)

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Book Synopsis Man-made Vitreous Fibres by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Man-made Vitreous Fibres written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2002 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This publication represents the views and expert opinions of an IARC working group on the evaluation of carcinogenic risks to humans, which met in Lyon, 9-16 October 2001."

Diet Nutrition And Cancer

Author : National Research Council
Publisher : Legare Street Press
ISBN 13 : 9781015698871
Total Pages : 0 pages
Book Rating : 4.6/5 (988 download)

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Book Synopsis Diet Nutrition And Cancer by : National Research Council

Download or read book Diet Nutrition And Cancer written by National Research Council and published by Legare Street Press. This book was released on 2022-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Environmental Toxicants

Author : Morton Lippmann
Publisher : John Wiley & Sons
ISBN 13 : 0470442883
Total Pages : 1189 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Environmental Toxicants by : Morton Lippmann

Download or read book Environmental Toxicants written by Morton Lippmann and published by John Wiley & Sons. This book was released on 2009-03-26 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles

A Review of Human Carcinogens

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (815 download)

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Book Synopsis A Review of Human Carcinogens by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference

Download or read book A Review of Human Carcinogens written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carcinogenicity of Inorganic Substances

Author : J H Duffus
Publisher : Woodhead Publishing
ISBN 13 : 1782424415
Total Pages : 296 pages
Book Rating : 4.7/5 (824 download)

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Book Synopsis Carcinogenicity of Inorganic Substances by : J H Duffus

Download or read book Carcinogenicity of Inorganic Substances written by J H Duffus and published by Woodhead Publishing. This book was released on 2014-01-31 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the state of scientific knowledge about the carcinogenicity of metals, their compounds and other inorganic substances. It provides a valuable guide for chemists involved in risk assessment, health and safety and toxicology.

Molecular and Cellular Mechanisms of Toxicity

Author : Francesco De Matteis
Publisher : CRC Press
ISBN 13 : 9781439805589
Total Pages : 244 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Molecular and Cellular Mechanisms of Toxicity by : Francesco De Matteis

Download or read book Molecular and Cellular Mechanisms of Toxicity written by Francesco De Matteis and published by CRC Press. This book was released on 1995-09-25 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by specialists in their fields, this book contains short reviews intended to highlight points of growing interest in mechanistic toxicology. The first section considers selected aspects of molecular mechanisms, including selectivity of toxic agents and repair processes in the nervous system, toxicity of oxygen, fibers and aflatoxins. The second section discusses the interactions of carcinogens with DNA, and other targets, and their relevance to both molecular dosimetry of exposure and development of cancer. The final part is concerned with cellular and genetic aspects and includes coverage of some of the most recent and rapidly developing problems in toxicology.

Environmental Health Perspectives

Author :
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres

Author : John M.G. Davis
Publisher : Springer Science & Business Media
ISBN 13 : 3642790410
Total Pages : 434 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres by : John M.G. Davis

Download or read book Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres written by John M.G. Davis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presented here are recent data on the mechanisms of action of different dusts and fibres of industrial interest. Emphasis is placed on the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occurring after their interaction with fibrous and non-fibrous particulates including metal compounds. In four sections, the volume provides research findings in the following areas: - Cellular and Metabolic Changes Caused by Mineral Dusts - Molecular Changes and DNA Alterations Produced by Mineral Dusts - In Vivo Dust-Related Pathological Processes. Correlations Between in Vitro and in Vivo Data - Physico-Chemical Properties of Minerals in Relation to Their Biological Effects.

Principles of Tumors

Author : Leon P. Bignold
Publisher : Academic Press
ISBN 13 : 0128173297
Total Pages : 686 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Principles of Tumors by : Leon P. Bignold

Download or read book Principles of Tumors written by Leon P. Bignold and published by Academic Press. This book was released on 2019-11-01 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Tumors: A Translational Approach to Foundations, Second Edition, provides a concise summary of translational/interdisciplinary topics on the various aspects of tumors, especially abnormalities in their cells, their causes and effects on patients. Topics discussed include how genomic abnormalities in tumors may result from the actions of carcinogens and how genomic changes determine the cell biological/morphological abnormalities in tumor cell populations. In addition, the relationships between tumor cell genomics and therapeutic outcomes are described. There are also supporting appendices on general bioscience, including the principles of histology (the cells and tissues of the body), genetics, pathology, radiology and pharmacology. This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine. Presents content that has been totally updated with the most recent developments of the field, including new chapters on tumor imaging exams, new surgical techniques, immunotherapy, gene therapy, and several novel therapies using natural and synthetic compounds Presents translational approaches for every topic to improve conceptual insights for new research projects Covers a broad range of subjects, making it easier for the reader to understand related fields Includes diagrams for complex topics to aid in understanding for non-specialists

Biopersistence of Respirable Synthetic Fibers and Minerals

Author :
Publisher :
ISBN 13 :
Total Pages : 314 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Biopersistence of Respirable Synthetic Fibers and Minerals by :

Download or read book Biopersistence of Respirable Synthetic Fibers and Minerals written by and published by . This book was released on 1994 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Malignant Pleural Mesothelioma

Author : Kenneth O'Byrne
Publisher : Oxford University Press
ISBN 13 : 0191566926
Total Pages : pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Malignant Pleural Mesothelioma by : Kenneth O'Byrne

Download or read book Malignant Pleural Mesothelioma written by Kenneth O'Byrne and published by Oxford University Press. This book was released on 2006-11-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and is expected to kill over 100,000 people worldwide. As malignant pleural mesothelioma gains in profile, Kenneth O'Byrne and Valerie Rusch present a comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease. The book includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, radiotherapy, and palliative medicine, written by an international team of contributors. A molecular biology section focuses on the carcinogenic effects of asbestos fibres and simian virus 40, angiogenesis and angiogenic growth factors, the immune response, and genetic abnormalities detected in the disease. Future therapies are also covered, as is a perspective on the distinct legal issues related to the disease. This highly-illustrated, full colour book provides the ultimate, timely resource on this devastating disease.

Mechanisms of Carcinogenesis

Author : Elizabeth K. Weisburger
Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Elizabeth K. Weisburger

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.