Mechanisms, imaging techniques, and therapies for acute ischemic stroke and related neuroprotective strategies

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Publisher : Frontiers Media SA
ISBN 13 : 2832534767
Total Pages : 122 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Mechanisms, imaging techniques, and therapies for acute ischemic stroke and related neuroprotective strategies by : Xunming Ji

Download or read book Mechanisms, imaging techniques, and therapies for acute ischemic stroke and related neuroprotective strategies written by Xunming Ji and published by Frontiers Media SA. This book was released on 2023-10-03 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Acute Ischemic Stroke

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Publisher : Springer Science & Business Media
ISBN 13 : 3642127517
Total Pages : 299 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Acute Ischemic Stroke by : R. Gilberto González

Download or read book Acute Ischemic Stroke written by R. Gilberto González and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Textbook of Stroke Medicine

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Publisher : Cambridge University Press
ISBN 13 : 1107047498
Total Pages : 425 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Textbook of Stroke Medicine by : Michael Brainin

Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.

Stroke Therapy

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Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stroke Therapy by : Marc Fisher

Download or read book Stroke Therapy written by Marc Fisher and published by Butterworth-Heinemann. This book was released on 2001 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition keeps you up to date with the exciting new developments in treating cerebrovascular disorders. Comprehensive and practical, it surveys methods for accurate stroke diagnosis necessary for you to make appropriate therapeutic decisions.

Cerebral Ischemia

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Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.:/5 (129 download)

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Book Synopsis Cerebral Ischemia by : Ryszard M. Pluta

Download or read book Cerebral Ischemia written by Ryszard M. Pluta and published by . This book was released on 2021 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral ischemia is one of the most common causes of dementia, which develops in more than half of patients after an ischemic episode. The main mechanism is thought to be pathological changes in the hippocampus, especially in the CA1 area, underlying episodic memory impairment, which is the earliest and most important clinical symptom of post-ischemic dementia. The 13 chapters of this book present a new picture of ischemic brain disease, synthesizing the latest data on disease mechanisms, care for patients with this disease, and potential therapeutic targets. The authors present the characteristics of cerebral ischemia from pregnancy and childhood through adolescence to adulthood. The first two chapters provide a snapshot of the anatomy of the cerebral cortex and the hippocampus, the most affected brain structures after cerebral ischemia. This is followed by nine chapters that present a comprehensive view of the pathological mechanisms of cerebral ischemia, and how a deep understanding of these pathomechanisms hold the key for the discovery and development of novel therapies to help patients affected by cerebral ischemia. Chapter 12 shares real-life experience and challenges of rehabilitating patients into the community after cerebral ischemia, and chapter 13 analyzes the social risk variations, including gender inequality, in the reintegration of post-ischemic stroke patients. Although primarily aimed at scientists and clinicians, the contents of the book will be of interest to all those who are interested in cerebral ischemia, including patients and their caregivers.

Magnesium in the Central Nervous System

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Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

The Stroke Book

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Publisher : Cambridge University Press
ISBN 13 : 1107634725
Total Pages : 395 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis The Stroke Book by : Michel T. Torbey

Download or read book The Stroke Book written by Michel T. Torbey and published by Cambridge University Press. This book was released on 2013-07-18 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.

Inflammation and Stroke

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Publisher : Springer
ISBN 13 : 3034882971
Total Pages : 351 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Inflammation and Stroke by : Giora Z. Feuerstein

Download or read book Inflammation and Stroke written by Giora Z. Feuerstein and published by Springer. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.

2-Oxoglutarate-Dependent Oxygenases

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849739501
Total Pages : 508 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis 2-Oxoglutarate-Dependent Oxygenases by : Christopher J Schofield

Download or read book 2-Oxoglutarate-Dependent Oxygenases written by Christopher J Schofield and published by Royal Society of Chemistry. This book was released on 2015-05-06 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the first examples of 2-oxoglutarate-dependent oxygenase-catalysed reactions in the 1960s, a remarkably broad diversity of alternate reactions and substrates has been revealed, and extensive advances have been achieved in our understanding of the structures and catalytic mechanisms. These enzymes are important agrochemical targets and are being pursued as therapeutic targets for a wide range of diseases including cancer and anemia. This book provides a central source of information that summarizes the key features of the essential group of 2-oxoglutarate-dependent dioxygenases and related enzymes. Given the numerous recent advances and biomedical interest in the field, this book aims to unite the latest research for those already working in the field as well as to provide an introduction for those newly approaching the topic, and for those interested in translating the basic science into medicinal and agricultural benefits. The book begins with four broad chapters that highlight critical aspects, including an overview of possible catalytic reactions, structures and mechanisms. The following seventeen chapters focus on carefully selected topics, each written by leading experts in the area. Readers will find explanations of rapidly evolving research, from the chemistry of isopenicillin N synthase to the oxidation mechanism of 5-methylcytosine in DNA by ten-eleven-translocase oxygenases.

Oxford Textbook of Neuroscience and Anaesthesiology

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Publisher : Oxford University Press
ISBN 13 : 0191063541
Total Pages : 351 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Neuroscience and Anaesthesiology by : George A. Mashour

Download or read book Oxford Textbook of Neuroscience and Anaesthesiology written by George A. Mashour and published by Oxford University Press. This book was released on 2019-01-10 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The perioperative care of individuals with neurologic compromise is critically important, yet it is only one dimension of the rich relationship between anaesthesiology and the neurosciences. The mechanism of everyday therapeutic interventions such as anaesthesia and analgesia is exciting neuroscience in its own right. At the new frontier of outcomes studies lies the question of how the perioperative period might impact the brain. For example, questions related to anaesthetic neurotoxicity, delirium, and cognitive dysfunction pose critical challenges for the field. The Oxford Textbook in Neuroscience and Anaesthesiology addresses the exciting field of neuroanaesthesiology in a new and stimulating way. In twenty eight chapters, the neuroscientific basis of anaesthesiology, the full spectrum of clinical neuroanaesthesia, and the care of neurologic patients undergoing non-neurologic surgery are explored in one comprehensive textbook for the first time. The first section considers the neural mechanisms of general anaesthetics, cerebral physiology, the neurobiology of pain, and more. The second section explores the care of patients with neurologic disease in the operating room or intensive care unit. These clinical chapters systematically treat the perioperative considerations of both brain and spine surgery, and provide introductions to neurocritical care and pediatric neuroanaesthesia. The final section outlines the care of neurologic patients undergoing non-neurologic surgery. It examines key connections of neurology and anaesthesiology, examining how conditions such as dementia, stroke, or epilepsy interface with the perioperative period. Each chapter has been carefully crafted to be concise yet highly informative, reflecting the cutting edge of neuroscience and neuroanaesthesiology. This international textbook gathers the best available expertise of authors and leaders worldwide. Includes access to online-only content, including more than 20 cases and more than 90 questions that can be used in presentations and teaching sessions. By activating your unique access code, you can access and use the material.

Brain Repair After Stroke

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Publisher : Cambridge University Press
ISBN 13 : 1139490656
Total Pages : 307 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Brain Repair After Stroke by : Steven C. Cramer

Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Warlow's Stroke

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Publisher : John Wiley & Sons
ISBN 13 : 1118492420
Total Pages : 1008 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Warlow's Stroke by : Graeme J. Hankey

Download or read book Warlow's Stroke written by Graeme J. Hankey and published by John Wiley & Sons. This book was released on 2019-01-22 with total page 1008 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical textbook, based on a problem-oriented workflow, that will improve patients' likelihood of full recovery from stroke and prevent future strokes from occurring Stroke is the leading cause of adult disability and is in the top five causes of death globally. Warlow's Stroke: Practical Management, 4th Edition takes a problem-oriented approach and addresses the questions posed by a stroke patient in the order they are likely to present in clinical practice, for instance, 'Is it a stroke?', 'What sort of stroke?', 'What caused it?', and 'What can be done about it?'. Beginning with chapters phrased as questions, the book walks the reader through a standard clinical workflow, exploring the practical skills and assessment required at each stage of patient management. Early chapters cover: locating the vascular lesion, identifying the involved arterial territory, the role imaging should play, and the application thereof. Subsequent chapters look at what causes a transient or persistent ischemic event, an intracerebral hemorrhage and a subarachnoid hemorrhage. Unusual causes of ischemic stroke and transient ischemic attack are also covered. The book then presents a practical approach to the management of stroke and transient ischemic attack; offers specific treatments for acute ischemic stroke and aneurysmal subarachnoid hemorrhage; provides ways for professionals to prevent first or recurrent stroke; and more. Final chapters of the book discuss rehabilitation after stroke, how patients and carers can be supported in the short term and long term, prevention of recurrent stroke, and the organization of stroke services. Warlow's Stroke: Practical Management, 4th Edition Follows clinical workflow for stroke analysis Features evidence-based approach throughout Offers practical application aimed at improving patient outcomes Written and edited by internationally renowned experts in the field An essential resource for all practitioners involved in the care of patients who suffer from cerebrovascular disease, but particularly suitable for neurologists, residents, geriatricians, stroke physicians, radiologists and primary care physicians.

Mechanisms of Disease

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Publisher : Cambridge University Press
ISBN 13 : 1139469495
Total Pages : 305 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Mechanisms of Disease by : Stephen Tomlinson

Download or read book Mechanisms of Disease written by Stephen Tomlinson and published by Cambridge University Press. This book was released on 2008-03-20 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: To reflect the changing face of undergraduate and postgraduate medical education, this new edition emphasises the principles of disease processes and their underlying mechanisms, bringing the content up to date with the latest developments from the fields of molecular and cellular biology. The focus is on describing the fundamental features of pathophysiological processes with examples to illustrate the similar mechanisms underlying apparently diverse clinical conditions. By understanding the cellular interactions in one disease area, similar principles can be applied to other disease groups and to the scientific basis of medical management and treatment strategies. Throughout, the student is encouraged to evaluate and integrate the evidence critically, developing skills for self-directed learning and the application of knowledge. To further encourage the reader to integrate the theory with clinical practice, each chapter concludes with a series of clinical scenarios and MCQs, with answers provided.

Molecular and Cellular Biology of Neuroprotection in the CNS

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Publisher : Springer
ISBN 13 : 9781461349341
Total Pages : 0 pages
Book Rating : 4.3/5 (493 download)

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Book Synopsis Molecular and Cellular Biology of Neuroprotection in the CNS by : Christian Alzheimer

Download or read book Molecular and Cellular Biology of Neuroprotection in the CNS written by Christian Alzheimer and published by Springer. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases. This book brings together leading experts from neurobiology, neurophysiology, neuropharmacology, neuroimmunology and clinical neuroscience to highlight the most recent milestones in this rapidly evolving field. The book will serve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies.

Stroke

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Publisher : Biota Publishing
ISBN 13 : 1615045872
Total Pages : 102 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Stroke by : Jens Minnerup

Download or read book Stroke written by Jens Minnerup and published by Biota Publishing. This book was released on 2013-08-01 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major global health problem because of its large contribution to mortality, morbidity, and disability. The most common form of stroke is ischemic stroke which accounts for approximately 80% of all strokes. During the past decade, our knowledge of the molecular and cellular processes that contribute to stroke pathophysiology has increased substantially and offers many targets for future therapeutic strategies. This book provides an overview of the current knowledge of stroke pathophysiology and the mechanisms that interfere with recovery and regeneration. Moreover, this book reviews the latest advances in the development of future therapeutic strategies.

Neuroinflammation in Stroke

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Publisher : Springer Science & Business Media
ISBN 13 : 3662054264
Total Pages : 224 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Neuroinflammation in Stroke by : Ulrich Dirnagl

Download or read book Neuroinflammation in Stroke written by Ulrich Dirnagl and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The successful treatment of acute stroke remains one of the major challenges in clinical medicine. Over the last decades, the understanding of stroke pathophysiology has greatly improved, while the therapeutic options in stroke therapy remain very limited. Today, hyperacute mechanisms of damage, such as excitotoxicity, can be discriminated from delayed ones, such as inflammation and apoptosis. Targeting of inflammation has already been successfully applied in various stroke models, but translation into a clinically efficacious strategy has not been achieved so far. In this book, leading experts in basic cerebrovascular research as well as stroke treatment review the current evidence for and against an important role for inflammation in stroke, and explore the potential of treating or modulating inflammation in stroke therapy.

Oxford Textbook of Stroke and Cerebrovascular Disease

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Author :
Publisher : Oxford Textbooks in Clinical N
ISBN 13 : 019964120X
Total Pages : 306 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Stroke and Cerebrovascular Disease by : Bo Norrving

Download or read book Oxford Textbook of Stroke and Cerebrovascular Disease written by Bo Norrving and published by Oxford Textbooks in Clinical N. This book was released on 2014 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical volume covers the current pedagogic principles of stroke disease and care, including the acute hospital phase, public health issues, prevention, long-term management, and silent vascular disease.