Mathematical and Computational Studies on Progress, Prognosis, Prevention and Panacea of Breast Cancer

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Publisher : Springer Nature
ISBN 13 : 9811660778
Total Pages : 377 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Mathematical and Computational Studies on Progress, Prognosis, Prevention and Panacea of Breast Cancer by : Suhrit Dey

Download or read book Mathematical and Computational Studies on Progress, Prognosis, Prevention and Panacea of Breast Cancer written by Suhrit Dey and published by Springer Nature. This book was released on 2022-03-25 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book’s aim is to study the mathematical and computational models to analyze the progress, prognosis, prevention, and panacea of breast cancer. The book discusses application of Markov chains and transient mappings, Charlie–Simpson numerical algorithm, models represented by nonlinear reaction–diffusion-type partial differential equations, and related techniques. The book also attempts to design mathematical model of targeted strategic treatments by using Skilled Killer Drugs (SKD1 and SKD2) to suggest the improvisation of future cancer treatments. Both graduate students and researchers of computational biology and oncologists will benefit by studying this book. Researchers of cancer studies and biological sciences will also find this work helpful.

Perturbed Functional Iterations

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Publisher : CRC Press
ISBN 13 : 1040014933
Total Pages : 327 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Perturbed Functional Iterations by : Suhrit Dey

Download or read book Perturbed Functional Iterations written by Suhrit Dey and published by CRC Press. This book was released on 2024-06-28 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perturbed functional iterations (PFI) is a large‐scale nonlinear system solver. Nature is abundant with events simulated mathematically by nonlinear systems of equations and inequalities. These we call nonlinear models. Often, they are ill‐conditioned, meaning small changes in data causing huge changes in the output. PFI, previously called the perturbed iterative scheme (PIS), is a numerical method to solve nonlinear systems of equations in multidimensional space. Computational results demonstrate that this numerical method has some unique features, which have made it more practical for applications in engineering and applied mathematics. This book will guide readers in the proper use of PFI, both in theoretical and practical settings. Features: Ideal resource for postgraduates and professional researchers in science and engineering working in nonlinear systems Algorithmically simple enough for engineers and applied scientists to write their own software based on the contents

Charting the Course

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Publisher :
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Charting the Course by : National Cancer Institute (U.S.). Breast Cancer Progress Review Group

Download or read book Charting the Course written by National Cancer Institute (U.S.). Breast Cancer Progress Review Group and published by . This book was released on 1998 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Gynecology

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Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Delivering High-Quality Cancer Care

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Publisher : National Academies Press
ISBN 13 : 9780309286602
Total Pages : 0 pages
Book Rating : 4.2/5 (866 download)

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Book Synopsis Delivering High-Quality Cancer Care by : Committee on Improving the Quality of Cancer Care: Addressing the Challenges of an Aging Population

Download or read book Delivering High-Quality Cancer Care written by Committee on Improving the Quality of Cancer Care: Addressing the Challenges of an Aging Population and published by National Academies Press. This book was released on 2014-01-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the United States, approximately 14 million people have had cancer and more than 1.6 million new cases are diagnosed each year. However, more than a decade after the Institute of Medicine (IOM) first studied the quality of cancer care, the barriers to achieving excellent care for all cancer patients remain daunting. Care often is not patient-centered, many patients do not receive palliative care to manage their symptoms and side effects from treatment, and decisions about care often are not based on the latest scientific evidence. The cost of cancer care also is rising faster than many sectors of medicine--having increased to $125 billion in 2010 from $72 billion in 2004--and is projected to reach $173 billion by 2020. Rising costs are making cancer care less affordable for patients and their families and are creating disparities in patients' access to high-quality cancer care. There also are growing shortages of health professionals skilled in providing cancer care, and the number of adults age 65 and older--the group most susceptible to cancer--is expected to double by 2030, contributing to a 45 percent increase in the number of people developing cancer. The current care delivery system is poorly prepared to address the care needs of this population, which are complex due to altered physiology, functional and cognitive impairment, multiple coexisting diseases, increased side effects from treatment, and greater need for social support. Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis presents a conceptual framework for improving the quality of cancer care. This study proposes improvements to six interconnected components of care: (1) engaged patients; (2) an adequately staffed, trained, and coordinated workforce; (3) evidence-based care; (4) learning health care information technology (IT); (5) translation of evidence into clinical practice, quality measurement and performance improvement; and (6) accessible and affordable care. This report recommends changes across the board in these areas to improve the quality of care. Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis provides information for cancer care teams, patients and their families, researchers, quality metrics developers, and payers, as well as HHS, other federal agencies, and industry to reevaluate their current roles and responsibilities in cancer care and work together to develop a higher quality care delivery system. By working toward this shared goal, the cancer care community can improve the quality of life and outcomes for people facing a cancer diagnosis.

Social Monitoring for Public Health

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1681736101
Total Pages : 188 pages
Book Rating : 4.6/5 (817 download)

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Book Synopsis Social Monitoring for Public Health by : Michael J. Paul

Download or read book Social Monitoring for Public Health written by Michael J. Paul and published by Morgan & Claypool Publishers. This book was released on 2017-08-31 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health thrives on high-quality evidence, yet acquiring meaningful data on a population remains a central challenge of public health research and practice. Social monitoring, the analysis of social media and other user-generated web data, has brought advances in the way we leverage population data to understand health. Social media offers advantages over traditional data sources, including real-time data availability, ease of access, and reduced cost. Social media allows us to ask, and answer, questions we never thought possible. This book presents an overview of the progress on uses of social monitoring to study public health over the past decade. We explain available data sources, common methods, and survey research on social monitoring in a wide range of public health areas. Our examples come from topics such as disease surveillance, behavioral medicine, and mental health, among others. We explore the limitations and concerns of these methods. Our survey of this exciting new field of data-driven research lays out future research directions.

Design and Implementation of Health Information Systems

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Publisher :
ISBN 13 : 9789241561990
Total Pages : 270 pages
Book Rating : 4.5/5 (619 download)

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Book Synopsis Design and Implementation of Health Information Systems by : World Health Organization Staff

Download or read book Design and Implementation of Health Information Systems written by World Health Organization Staff and published by . This book was released on 2000 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical guide to the design and implementation of health information systems in developing countries. Noting that most existing systems fail to deliver timely, reliable, and relevant information, the book responds to the urgent need to restructure systems and make them work as both a resource for routine decisions and a powerful tool for improving health services. With this need in mind, the authors draw on their extensive personal experiences to map out strategies, pinpoint common pitfalls, and guide readers through a host of conceptual and technical options. Information needs at all levels - from patient care to management of the national health system - are considered in this comprehensive guide. Recommended lines of action are specific to conditions seen in government-managed health systems in the developing world. In view of common constraints on time and resources, the book concentrates on strategies that do not require large resources, highly trained staff, or complex equipment. Throughout the book, case studies and numerous practical examples are used to explore problems and illustrate solutions. Details range from a list of weaknesses that plague most existing systems, through advice on when to introduce computers and how to choose appropriate software and hardware, to the hotly debated question of whether patient records should be kept by the patient or filed at the health unit. The book has fourteen chapters presented in four parts. Chapters in the first part, on information for decision-making, explain the potential role of health information as a managerial tool, consider the reasons why this potential is rarely realized, and propose general approaches for reform which have proved successful in several developing countries. Presentation of a six-step procedure for restructuring information systems, closely linked to an organizational model of health services, is followed by a practical discussion of the decision-making process. Reasons for the failure of most health information to influence decisions are also critically assessed. Against this background, the second and most extensive part provides a step-by-step guide to the restructuring of information systems aimed at improving the quality and relevance of data and ensuring their better use in planning and management. Steps covered include the identification of information needs and indicators, assessment of the existing system, and the collection of both routine and non-routine data using recommended procedures and instruments. Chapters also offer advice on procedures for data transmission and processing, and discuss the requirements of systems designed to collect population-based community information. Resource needs and technical tools are addressed in part three. A comprehensive overview of the resource base - from staff and training to the purchase and maintenance of equipment - is followed by chapters offering advice on the introduction of computerized systems in developing countries, and explaining the many applications of geographic information systems. Practical advice on how to restructure a health information system is provided in the final part, which considers how different interest groups can influence the design and implementation of a new system, and proposes various design options for overcoming specific problems. Experiences from several developing countries are used to illustrate strategies and designs in terms of those almost certain to fail and those that have the greatest chances of success

Organic Cation Transporter 1 (OCT1): Not Vital for Life, but of Substantial Biomedical Relevance

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889740293
Total Pages : 145 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Organic Cation Transporter 1 (OCT1): Not Vital for Life, but of Substantial Biomedical Relevance by : Jurgen Brockmoller

Download or read book Organic Cation Transporter 1 (OCT1): Not Vital for Life, but of Substantial Biomedical Relevance written by Jurgen Brockmoller and published by Frontiers Media SA. This book was released on 2022-01-12 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Around one third of all biologically relevant small molecules are organic cations. These include endogenous substances like catecholamines and other neurotransmitters, toxins and drugs designed to affect signaling processes. The organic cation transporter 1 (OCT1) is among the strongest expressed membrane transporters at the sinusoidal (blood-facing) side of liver cells and contributes substantially to the clearance of the blood from numerous organic cations. A most striking feature of OCT1 is its pronounced genetic diversity. Between 1 and 10% of all human populations have little to no OCT1 activity. With several of the OCT1 substrates up to 10% of Europeans are functionally OCT1 deficient. Apparently, the lack of OCT1 do not lead to apparent substantial pathological changes in these individuals. It thus appears that this transporter is not essential to human life, but does it means that OCT1 is irrelevant? In the last 25 years since the first cloning of this transporter, data on its pharmacological and physiological relevance is steadily accumulating. Numerous clinically relevant drugs (e.g. metformin, morphine, fenoterol, sumatriptan, tramadol and tropisetron) have been shown to be substrates of OCT1, and OCT1 deficiency has been shown to affect the pharmacokinetics, efficacy, or toxicity of these drugs. Also vitamin B1 has been shown to be a substrate of OCT1, and in genetically modified mice OCT1 substantially modulated hepatic lipid metabolism, total body fat and systemic glucose and lipid concentrations. Still, numerous important questions remain unsolved: For which drugs, toxins, or other endogenous or exogenous substances is OCT1 relevant? How can we predict the relevance of OCT1 from in vitro studies? What determines the substrate selectivity of OCT1 in comparison to other transporters or transport processes for organic cations? What regulates the expression of OCT1 in the liver and possibly in other tissues? What is the impact of OCT1 variation in different areas of medicine, including the therapies for cancer as well as for pulmonary, cardiovascular, or neurological diseases? How can evolutionary biology contribute to a better understanding of the roles of OCT1? And, importantly, what types of research are likely to significantly further the knowledge on OCT1 in the next decades?

Experimental and Quasi-Experimental Designs for Research

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Publisher : Ravenio Books
ISBN 13 :
Total Pages : 172 pages
Book Rating : 4./5 ( download)

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Book Synopsis Experimental and Quasi-Experimental Designs for Research by : Donald T. Campbell

Download or read book Experimental and Quasi-Experimental Designs for Research written by Donald T. Campbell and published by Ravenio Books. This book was released on 2015-09-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: We shall examine the validity of 16 experimental designs against 12 common threats to valid inference. By experiment we refer to that portion of research in which variables are manipulated and their effects upon other variables observed. It is well to distinguish the particular role of this chapter. It is not a chapter on experimental design in the Fisher (1925, 1935) tradition, in which an experimenter having complete mastery can schedule treatments and measurements for optimal statistical efficiency, with complexity of design emerging only from that goal of efficiency. Insofar as the designs discussed in the present chapter become complex, it is because of the intransigency of the environment: because, that is, of the experimenter’s lack of complete control.

Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers

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Publisher : Mdpi AG
ISBN 13 : 9783036526874
Total Pages : 298 pages
Book Rating : 4.5/5 (268 download)

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Book Synopsis Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers by : Veysel Kayser

Download or read book Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers written by Veysel Kayser and published by Mdpi AG. This book was released on 2022-01-25 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody-Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint inhibitors and other closely related topics. Each paper was written by leading active research groups in their fields both from academia and industry. The book should be of interest to those scientists and researchers who develop or use biologics, biotherapeutics, biosimilars and biobetters in cancer treatment.

Behavioral Economics and Public Health

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Publisher : Oxford University Press, USA
ISBN 13 : 019939833X
Total Pages : 385 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Behavioral Economics and Public Health by : Christina A. Roberto

Download or read book Behavioral Economics and Public Health written by Christina A. Roberto and published by Oxford University Press, USA. This book was released on 2016 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral economics has potential to offer novel solutions to some of today's most pressing public health problems: How do we persuade people to eat healthy and lose weight? How can health professionals communicate health risks in a way that is heeded? How can food labeling be modified to inform healthy food choices? Behavioral Economics and Public Health is the first book to apply the groundbreaking insights of behavioral economics to the persisting problems of health behaviors and behavior change. In addition to providing a primer on the behavioral economics principles that are most relevant to public health, this book offers details on how these principles can be employed to mitigating the world's greatest health threats, including obesity, smoking, risky sexual behavior, and excessive drinking. With contributions from an international team of scholars from psychology, economics, marketing, public health, and medicine, this book is a trailblazing new approach to the most difficult and important problems of our time.

Biodiversity and Human Health

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Publisher : Island Press
ISBN 13 : 9781559635004
Total Pages : 0 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis Biodiversity and Human Health by : Francesca Grifo

Download or read book Biodiversity and Human Health written by Francesca Grifo and published by Island Press. This book was released on 1997-02-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The implications of biodiversity loss for the global environment have been widely discussed, but only recently has attention been paid to its direct and serious effects on human health. Biodiversity loss affects the spread of human diseases, causes a loss of medical models, diminishes the supplies of raw materials for drug discovery and biotechnology, and threatens food production and water quality. Biodiversity and Human Health brings together leading thinkers on the global environment and biomedicine to explore the human health consequences of the loss of biological diversity. Based on a two-day conference sponsored by the National Institutes of Health, the National Science Foundation, and the Smithsonian Institution, the book opens a dialogue among experts from the fields of public health, biology, epidemiology, botany, ecology, demography, and pharmacology on this vital but often neglected concern. Contributors discuss the uses and significance of biodiversity to the practice of medicine today, and develop strategies for conservation of these critical resources. Topics examined include: the causes and consequences of biodiversity loss emerging infectious diseases and the loss of biodiversity the significance and use of both prescription and herbal biodiversity-derived remedies indigenous and local peoples and their health care systems sustainable use of biodiversity for medicine an agenda for the future In addition to the editors, contributors include Anthony Artuso, Byron Bailey, Jensa Bell, Bhaswati Bhattacharya, Michael Boyd, Mary S. Campbell, Eric Chivian, Paul Cox, Gordon Cragg, Andrew Dobson, Kate Duffy-Mazan, Robert Engelman, Paul Epstein, Alexandra S. Fairfield, John Grupenhoff, Daniel Janzen, Catherine A. Laughin, Katy Moran, Robert McCaleb, Thomas Mays, David Newman, Charles Peters, Walter Reid, and John Vandermeer. The book provides a common framework for physicians and biomedical researchers who wish to learn more about environmental concerns, and for members of the environmental community who desire a greater understanding of biomedical issues.

Using Discrete Choice Experiments to Value Health and Health Care

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Publisher : Springer Science & Business Media
ISBN 13 : 1402057539
Total Pages : 265 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Using Discrete Choice Experiments to Value Health and Health Care by : Mandy Ryan

Download or read book Using Discrete Choice Experiments to Value Health and Health Care written by Mandy Ryan and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work takes a fresh and contemporary look at the growing interest in the development and application of discrete choice experiments (DCEs) within the field of health economics. The book comprises chapters by highly regarded academics with experience of applying DCEs in the area of health. Thus the book is relevant to post-graduate students and applied researchers with an interest in the use of DCEs for valuing health and health care and has international appeal.

Systematic Reviews in the Social Sciences

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Publisher : John Wiley & Sons
ISBN 13 : 1405150149
Total Pages : 352 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Systematic Reviews in the Social Sciences by : Mark Petticrew

Download or read book Systematic Reviews in the Social Sciences written by Mark Petticrew and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Such diverse thinkers as Lao-Tze, Confucius, and U.S. Defense Secretary Donald Rumsfeld have all pointed out that we need to be able to tell the difference between real and assumed knowledge. The systematic review is a scientific tool that can help with this difficult task. It can help, for example, with appraising, summarising, and communicating the results and implications of otherwise unmanageable quantities of data. This book, written by two highly-respected social scientists, provides an overview of systematic literature review methods: Outlining the rationale and methods of systematic reviews; Giving worked examples from social science and other fields; Applying the practice to all social science disciplines; It requires no previous knowledge, but takes the reader through the process stage by stage; Drawing on examples from such diverse fields as psychology, criminology, education, transport, social welfare, public health, and housing and urban policy, among others. Including detailed sections on assessing the quality of both quantitative, and qualitative research; searching for evidence in the social sciences; meta-analytic and other methods of evidence synthesis; publication bias; heterogeneity; and approaches to dissemination.

Network Meta-Analysis for Decision-Making

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Publisher : John Wiley & Sons
ISBN 13 : 1118647505
Total Pages : 484 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Network Meta-Analysis for Decision-Making by : Sofia Dias

Download or read book Network Meta-Analysis for Decision-Making written by Sofia Dias and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.

The Cancer Atlas

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Publisher :
ISBN 13 : 9781604432282
Total Pages : 0 pages
Book Rating : 4.4/5 (322 download)

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Book Synopsis The Cancer Atlas by : Ahmedin Jemal

Download or read book The Cancer Atlas written by Ahmedin Jemal and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.

The Global Technology Revolution 2020, In-Depth Analyses: Bio/Nano/Materials/Information Trends, Drivers, Barriers, and Social Implications

Download The Global Technology Revolution 2020, In-Depth Analyses: Bio/Nano/Materials/Information Trends, Drivers, Barriers, and Social Implications PDF Online Free

Author :
Publisher : Rand Corporation
ISBN 13 : 0833041142
Total Pages : 332 pages
Book Rating : 4.8/5 (33 download)

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Book Synopsis The Global Technology Revolution 2020, In-Depth Analyses: Bio/Nano/Materials/Information Trends, Drivers, Barriers, and Social Implications by : Richard Silberglitt

Download or read book The Global Technology Revolution 2020, In-Depth Analyses: Bio/Nano/Materials/Information Trends, Drivers, Barriers, and Social Implications written by Richard Silberglitt and published by Rand Corporation. This book was released on 2002-08-30 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2020, areas of particular importance for technology trends will include biotechnology, nanotechnology, materials technology, and information technology. This report, the companion document to The Global Technology Revolution 2020, Executive Summary (Silberglitt et al., MG-475-NIC, 2006), assesses in detail a sample of 29 countries with respect to their ability to acquire and implement 16 key technology applications.