Management of Treatment-Resistant Major Psychiatric Disorders

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199974144
Total Pages : 384 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Management of Treatment-Resistant Major Psychiatric Disorders by : Charles B. Nemeroff MD, PhD

Download or read book Management of Treatment-Resistant Major Psychiatric Disorders written by Charles B. Nemeroff MD, PhD and published by Oxford University Press. This book was released on 2012-06-05 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although there are a variety of textbooks and manuals of psychiatric disorders, few have focused on the management of treatment-resistant patients. Those that exist have largely focused on treatment-resistant depression and even these are now largely outdated. Because psychiatrists and other mental health care professionals increasingly manage patients who fail treatment from family practitioners and other non-psychiatric specialists, a single practical volume summarizing the evidence-based medicine as well as the art of managing treatment-resistant patients is a much needed volume for practitioners, psychiatry residents and other mental health workers. Most importantly, both psychopharmacological and psychotherapeutic interventions will be included, a shortcoming of many previous volumes. "Management of Treatment Resistant Major Psychiatric Disorders" contains chapters authored by leaders in the field on the management of the major treatment resistant psychiatric disorders.

Management of Treatment-Resistant Major Psychiatric Disorders

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Author :
Publisher : OUP USA
ISBN 13 : 0199739986
Total Pages : 379 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Management of Treatment-Resistant Major Psychiatric Disorders by : Charles B. Nemeroff

Download or read book Management of Treatment-Resistant Major Psychiatric Disorders written by Charles B. Nemeroff and published by OUP USA. This book was released on 2012-06-05 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sizable percentage of patients with major psychiatric disorders do not respond to the first or second treatments they receive. This book summarizes the latest evidence from clinical studies concerning the treatment of patients with treatment-resistant psychiatric disorders. Both pharmacological and psychotherapeutic interventions are included, as well as somatic non-pharmacological treatments. The chapter authors represent the leaders in their respective fields.

Treatment Resistance in Psychiatry

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Author :
Publisher : Springer
ISBN 13 : 9811043582
Total Pages : 416 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Treatment Resistance in Psychiatry by : Yong-Ku Kim

Download or read book Treatment Resistance in Psychiatry written by Yong-Ku Kim and published by Springer. This book was released on 2018-10-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews all the important aspects of treatment-resistant psychiatric disorders, covering issues such as definitions, clinical aspects, neurobiological correlates, treatment options, and predictors of treatment response. The book is divided into three sections, the first of which examines the most recent thinking on treatment resistance in psychiatry, including definition and epidemiology, paradigm shift in the study of the subjects, individual susceptibility and resilience, abnormal structural or functional connectivity, and insights from animal models. The second section then discusses treatment resistance in each of the major psychiatric disorders, with particular focus on the responsible clinical and biological factors and the available management strategies. Finally, more detailed information is presented on diverse pharmacological and non-pharmacological therapeutic interventions. The book, written by leading experts from across the world, will be of value to all who seek a better understanding of the clinical-neurobiological underpinnings and the development of management for treatment resistance in psychiatric disorders.

Ketamine for Treatment-Resistant Depression

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Author :
Publisher : Academic Press
ISBN 13 : 0128210346
Total Pages : 170 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Ketamine for Treatment-Resistant Depression by : Gustavo H. Vazquez

Download or read book Ketamine for Treatment-Resistant Depression written by Gustavo H. Vazquez and published by Academic Press. This book was released on 2020-09-16 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. Provides efficacy research on ketamine as a treatment for depression Identifies best practices for clinical use, both long-term and acute Discusses the molecular mechanisms and neurobiology of action

Managing Treatment-Resistant Depression

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Author :
Publisher : Academic Press
ISBN 13 : 0128240687
Total Pages : 614 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Managing Treatment-Resistant Depression by : Joao Quevedo

Download or read book Managing Treatment-Resistant Depression written by Joao Quevedo and published by Academic Press. This book was released on 2022-03-31 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. Defines Treatment-Resistant Depression and Staging Treatment Intensity Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions Discusses the use of Ketamine and Esketamine for treatment-resistant depression

Treatment Resistant Depression

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Author :
Publisher : American Psychiatric Pub
ISBN 13 : 1585624098
Total Pages : 366 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis Treatment Resistant Depression by : John F. Greden

Download or read book Treatment Resistant Depression written by John F. Greden and published by American Psychiatric Pub. This book was released on 2011 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book presents the treatment "roadmap" implemented by the University of Michigan Comprehensive Depression Center's Treatment Resistant Depression Program, step-by-step guidance that has long eluded clinicians, patients, and their families. Writing across discipline, modality, lifespan, and patient demographics, the authors have compiled the most current thinking on TRD and distilled it into a highly readable, imminently practical, and brilliantly organized source of hope. The authors believe that early intervention is critical, and they advocate strategies for renewed focus on identifying youths who are at risk or already symptomatic. Similarly, they devote chapters to special populations such as pregnant women, older people, and those with comorbidities. Perhaps most useful to patients and their families, the book has a strong self-care orientation, emphasizing the importance of exercise, nutrition, and healthy sleep guidelines. Patients who are actively engaged in managing their disease often have better outcomes. Treatment Resistant Depression is frequently a lifetime diagnosis. The book acknowledges that fact and offers a systematic course of treatment grounded in evidence-based research that is current and comprehensive. Treatment Resistant Depression: A Roadmap for Effective Care offers a new way of conceptualizing an old enemy, and should prove to be an indispensable weapon in the battle.

Treatment-Resistant Depression

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118556739
Total Pages : 229 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Treatment-Resistant Depression by : Siegfried Kasper

Download or read book Treatment-Resistant Depression written by Siegfried Kasper and published by John Wiley & Sons. This book was released on 2013-02-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment-resistant Depress Successful management of patients with treatment-resistant depression requires a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of treatment-resistant depression originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors and gene variants have been identified as accounting for 50% of the variance in the clinical outcomes of antidepressant treatments. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, suggests that genetic prediction of treatment resistance could become a widespread clinical reality within a few years. Most patients with treatment-resistant depression will be treated pharmacologically, so three chapters review the latest evidence for pharmacological best practice in switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, explaining that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in treatment-resistant depression and summarizes general therapeutic principles. Essential reading for all psychiatrists managing patients with this distressing disorder.

Treatment-resistant Mood Disorders

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Author :
Publisher : Oxford Psychiatry Library
ISBN 13 : 0198707991
Total Pages : 175 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Treatment-resistant Mood Disorders by : André Carvalho

Download or read book Treatment-resistant Mood Disorders written by André Carvalho and published by Oxford Psychiatry Library. This book was released on 2015 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. Providing a concise view of the current definitions, assessment and evidence-based management of such disorders, this work reviews novel therapeutic targets, which may enhance the future therapeutic armamentarium of clinicians.

Treatment-Resistant Mood Disorders

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Author :
Publisher : OUP Oxford
ISBN 13 : 0191017841
Total Pages : 160 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Treatment-Resistant Mood Disorders by : André F Carvalho

Download or read book Treatment-Resistant Mood Disorders written by André F Carvalho and published by OUP Oxford. This book was released on 2015-03-26 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. The assessment and management of refractory patients with mood disorders is a major clinical challenge for mental health providers. Part of the Oxford Psychiatry Library (OPL) series, this pocketbook provides a concise view of the current definitions, assessment and evidence-based management of treatment-resistant mood disorders and reviews novel therapeutic targets for mood disorders, which may enhance the therapeutic armamentarium of clinicians in the near future. The pocketbook serves as a useful guide for mental health practitioners, including psychiatrists, clinical psychologists, trainees, and interested primary care physicians.

Ketamine for Treatment-Resistant Depression

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Author :
Publisher : Springer
ISBN 13 : 3319429256
Total Pages : 155 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Ketamine for Treatment-Resistant Depression by : Sanjay J. Mathew

Download or read book Ketamine for Treatment-Resistant Depression written by Sanjay J. Mathew and published by Springer. This book was released on 2016-11-25 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.

Treatment Resistant Depression

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Author :
Publisher : American Psychiatric Pub
ISBN 13 : 1585629537
Total Pages : 366 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis Treatment Resistant Depression by : University of Michigan Comprehensive Depression Center

Download or read book Treatment Resistant Depression written by University of Michigan Comprehensive Depression Center and published by American Psychiatric Pub. This book was released on 2011-03-28 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: As many as 35-40% of patients afflicted with Major Depressive Disorder (MDD) are treatment resistant, a situation that places a massive emotional and financial burden on society and challenges the mental health profession to develop new treatment paradigms and practices. Even the most astute clinicians can be frustrated when treatment options fail to be effective or work for only a brief time, leaving them to wonder what course to pursue next. Treatment Resistant Depression: A Roadmap for Effective Care gives clinicians and their patients what they need most desperately: a sequence of steps that reflect state-of-the-art diagnostic procedures and integrates all evidence-based treatment modalities -- in short, a roadmap to wellness and recovery. Based primarily on the experiences of the authors, all of whom are leading researchers and/or clinicians in Treatment Resistant Depression and affiliated with the University of Michigan Comprehensive Depression Center, the book also draws upon the clinical research advances and treatment innovations of programs around the world. Although the book's step-by-step organization is clear and easy to follow, its coverage, scope, and level of sophistication are anything but simplified. This book Is comprehensive, addressing treatment options, including psychopharmacotherapy, psychotherapy, neuromodulation (ECT, transcranial magnetic stimulation, deep brain stimulation, vagus nerve stimulation), exercise, nutrition, self-management approaches to enhance adherence, behavioral sleep programs, and others Addresses treatment resistant depression across the lifespan, reflecting the diverse demographics of depression, which knows no age, gender, or socioeconomic status Emphasizes the authors' commitment to early intervention and provides techniques for identifying young people who are at risk for developing depression or already expressing symptoms of the disease Recognizes the chronicity of depression, rather than focusing on only the acute stage, and in this way allows for more effective treatment over the patient's lifetime Introduces self-management as playing a critical role in the patient's prognosis, engagement, adherence to clinical steps that help maintain recovery, and self-esteem Promotes the development of new, personalized, and predictive biomarkers to target treatment more effectively. Designed to be useful across disciplines and treatment modalities, the book includes a multitude of tables, graphs, and learning aids that will benefit students, instructors, and clinicians. At the same time, the book promises to be a valuable resource for patients and their families, since Treatment Resistant Depression is both difficult to live with and little understood. No other book offers so much practical guidance, sound research and hope.

Psychopharmacology Algorithms

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975151216
Total Pages : 384 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Psychopharmacology Algorithms by : David Osser

Download or read book Psychopharmacology Algorithms written by David Osser and published by Lippincott Williams & Wilkins. This book was released on 2020-09-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algorithms serve an important purpose in the field of psychopharmacology as heuristics for avoiding the biases and cognitive lapses that are common when prescribing for many conditions whose treatment is based on complex data. Unique in the field, this title compiles twelve papers from the Psychopharmacology Algorithm Project at the Harvard South Shore Psychiatry Residency Training Program and presents practical ways to adopt evidence-based practices into the day-to-day treatment of patients. Psychopharmacology Algorithms is a useful resource for practicing psychiatrists, residents, and fellows, as well as psychiatric nurse practitioners, psychiatric physician assistants who prescribe, advanced practice pharmacists who prescribe, and primary care clinicians. Teachers of psychopharmacology may find it particularly valuable. Researchers in clinical psychopharmacology may find it helpful in identifying important practice areas that are in need of further study.

Major Depressive Disorder

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323581323
Total Pages : 202 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Major Depressive Disorder by : Roger S McIntyre

Download or read book Major Depressive Disorder written by Roger S McIntyre and published by Elsevier Health Sciences. This book was released on 2019-08-25 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the key issues surrounding best practices and current consensus on major depressive disorder (MDD). This concise resource by Drs. Roger S. McIntyre, Carola Rong, Mehala Subramaniapillai, and Yena Lee consolidates today’s available information on this complex topic into one convenient resource, making it an ideal, easy-to-digest reference for both psychiatrists and primary care physicians. Covers genetics and epigenetics, brain structural abnormalities, cognition, neuroendocrine alterations, and inflammatory abnormalities as they relate to MDD. Contains chapters on psychiatric comorbidity, pharmacological treatments, neuromodulatory treatments, lifestyle interventions, internet-based/technology-based interventions, and glutamate alterations.

Personalized Psychiatry

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Author :
Publisher : Academic Press
ISBN 13 : 0128131772
Total Pages : 604 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Personalized Psychiatry by : Bernhard Baune

Download or read book Personalized Psychiatry written by Bernhard Baune and published by Academic Press. This book was released on 2019-10-16 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Electroconvulsive Therapy in Children and Adolescents

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199937893
Total Pages : 311 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Electroconvulsive Therapy in Children and Adolescents by : Neera Ghaziuddin

Download or read book Electroconvulsive Therapy in Children and Adolescents written by Neera Ghaziuddin and published by Oxford University Press. This book was released on 2013-12 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a pioneering book about the use of ECT in adolescents who are diagnosed with severe, disabling psychiatric disorders or fail conventional treatment. Included are a review of the literature, firsthand experience of the authors and case descriptions making it an invaluable guide to treatment.

Selected Health Conditions and Likelihood of Improvement with Treatment

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Author :
Publisher : National Academies Press
ISBN 13 : 0309670950
Total Pages : 319 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Selected Health Conditions and Likelihood of Improvement with Treatment by : National Academies of Sciences, Engineering, and Medicine

Download or read book Selected Health Conditions and Likelihood of Improvement with Treatment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-12 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Panic Disorder and Agoraphobia

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199562296
Total Pages : 79 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Panic Disorder and Agoraphobia by : Borwin Bandelow

Download or read book Panic Disorder and Agoraphobia written by Borwin Bandelow and published by Oxford University Press. This book was released on 2013-09 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Psychiatry Library series, this pocketbook provides a user-friendly introduction to the diagnosis, etiology, and treatment of patients with panic disorder.