Mammalian Brain Development

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Publisher : Springer Science & Business Media
ISBN 13 : 1607612879
Total Pages : 227 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Mammalian Brain Development by : Damir Janigro

Download or read book Mammalian Brain Development written by Damir Janigro and published by Springer Science & Business Media. This book was released on 2009-09-18 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Denis Noble Nearly a decade after completion of the first draft of the entire Human Genome sequence we are in a better position to assess the nature and the consequences of that heroic achievement, which can be seen as the culmination of the molecular biological revolution of the second half of the twentieth century. The achievement itself was celebrated at the highest levels (President and Prime Minister) on both sides of the Atlantic, and rightly so. DNA sequencing has become sufficiently c- mon now, even to the extent of being used in law courts, that it is easy to forget how technically difficult it was and how cleverly the sequencing teams solved those problems in the exciting race to finish by the turn of the century [1, 2]. The fanfares were misplaced, however, in an important respect. The metaphors used to describe the project and its biological significance gave the impression to the public at large, and to many scientists themselves, that this sequence would reveal the secrets of life. DNA had already been likened to a computer program [3]. The “genetic program” for life was therefore to be found in those sequences: A kind of map that had simply to be unfolded during development. The even more colo- ful “book of life” metaphor gave the promise that reading that book would lead to a veritable outpouring of new cures for diseases, hundreds of new drug targets, and a brave new world of medicine.

Discovering the Brain

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Publisher : National Academies Press
ISBN 13 : 0309045290
Total Pages : 195 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Discovering the Brain by : National Academy of Sciences

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Mammalian Brain Development

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Publisher :
ISBN 13 : 9781607612889
Total Pages : 246 pages
Book Rating : 4.6/5 (128 download)

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Book Synopsis Mammalian Brain Development by : Damir Janigro

Download or read book Mammalian Brain Development written by Damir Janigro and published by . This book was released on 2009-09-20 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mouse Brain Development

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540480021
Total Pages : 347 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Mouse Brain Development by : Andre M. Goffinet

Download or read book Mouse Brain Development written by Andre M. Goffinet and published by Springer Science & Business Media. This book was released on 2012-08-10 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit nessed a quantum leap in our knowledge, due to technological improve ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno type. Nevertheless, the recent progress in genetics will allow us to contem plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop mental biology. The purpose of the present book is to provide an overview that syn thesizes up-to-date information on selected aspects of mouse brain devel opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.

The Fundamentals of Brain Development

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Publisher : Harvard University Press
ISBN 13 : 9780674026742
Total Pages : 452 pages
Book Rating : 4.0/5 (267 download)

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Book Synopsis The Fundamentals of Brain Development by : Joan Stiles

Download or read book The Fundamentals of Brain Development written by Joan Stiles and published by Harvard University Press. This book was released on 2008-02-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a remarkable synthesis of the research of the last two decades, a leading developmental neuroscientist provides psychologists with a sophisticated introduction to the brain—the system that underpins the functions that they study. In clear terms, with ample illustrations, Joan Stiles explains the complexities of genetic variation and transcription, and the variable paths of neural development, from embryology through early childhood. She describes early developmental processes from gene expression to physiology to behavior. Sections on clinical correlations show the consequences for later physiological, neurological, or psychological disturbances in neural development. As Stiles shows, brain development is far more complex and dynamic than is often assumed in debates about nature vs. nurture, nativism vs. cultural learning. Inherited and experienced factors interact constantly in an ever-changing organism. The key question is, what developmental processes give rise to particular structures or mechanisms? A landmark of synthesis and interdisciplinary illumination, The Fundamentals of Brain Development will enrich discussion of developmental processes and more rigorously define the terms that are central to psychological debates.

Mammalian Subventricular Zones

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Publisher : Springer Science & Business Media
ISBN 13 : 0387313893
Total Pages : 313 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Mammalian Subventricular Zones by : Steve Levison

Download or read book Mammalian Subventricular Zones written by Steve Levison and published by Springer Science & Business Media. This book was released on 2006-05-03 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive summary of research and findings that have lead to the current understanding of the subventricular zones. It provides an overview of the roles of subventricular zones in normal development and in disease and a foundation from which current and future studies can be evaluated.

Patterning and Cell Type Specification in the Developing CNS and PNS

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Publisher : Academic Press
ISBN 13 : 0123973481
Total Pages : 992 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Patterning and Cell Type Specification in the Developing CNS and PNS by :

Download or read book Patterning and Cell Type Specification in the Developing CNS and PNS written by and published by Academic Press. This book was released on 2013-05-06 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells

Neurobiology of Monotremes

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Publisher : CSIRO PUBLISHING
ISBN 13 : 0643103163
Total Pages : 626 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Neurobiology of Monotremes by : Ken Ashwell

Download or read book Neurobiology of Monotremes written by Ken Ashwell and published by CSIRO PUBLISHING. This book was released on 2013-12-01 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Monotremes brings together current information on the development, structure, function and behavioural ecology of the monotremes. The monotremes are an unusual and evolutionarily important group of mammals showing striking behavioural and physiological adaptations to their niches. They are the only mammals exhibiting electroreception (in the trigeminal sensory pathways) and the echidna shows distinctive olfactory specialisations. The authors aim to close the current gap in knowledge between the genes and developmental biology of monotremes on the one hand, and the adult structure, function and ecology of monotremes on the other. They explore how the sequence 'embryonic structure › adult structure › behaviour' is achieved in monotremes and how this differs from other mammals. The work also combines a detailed review of the neurobiology of monotremes with photographic and diagrammatic atlases of the sectioned adult brains and peripheral nervous system of the short-beaked echidna and platypus. Pairing of a detailed review of the field with the first published brain atlases of two of the three living monotremes will allow the reader to immediately relate key points in the text to features in the atlases and will extend a universal system of brain nomenclature developed in eutherian brain atlases by G Paxinos and colleagues to monotremes.

Evolution of the Horse Brain

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Publisher : Geological Society of America
ISBN 13 : 0813710251
Total Pages : 192 pages
Book Rating : 4.8/5 (137 download)

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Book Synopsis Evolution of the Horse Brain by : Tilly Edinger

Download or read book Evolution of the Horse Brain written by Tilly Edinger and published by Geological Society of America. This book was released on 1948 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Neurobiology of the Mammalian Brain

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Publisher : Springer Science & Business Media
ISBN 13 : 1461574919
Total Pages : 648 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular Neurobiology of the Mammalian Brain by : Patrick McGeer

Download or read book Molecular Neurobiology of the Mammalian Brain written by Patrick McGeer and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human brain is the inner universe through which all external events are perceived. That fact alone should ensure that neuroscience will eventually receive top priority in the list of human endeavors. The brain represents the pinnacle of sophistication in the realm of living systems. Yet it is an imperfect organ, whose failures in disease processes lead to the occupation of more than half of all hospital beds and whose variable performance in the healthy state contributes in undetermined degree to the world's social problems. Every significant advance in our understanding of the brain has yielded enormous practical dividends. There is every reason to believe the future holds even greater promise. It can be said that brain research took root near the end of the last century when Ram6n y Cajal proved beyond doubt that the neuron is the basic functioning unit of the brain and Sherrington revealed its method of transmitting impulses. But it is only in the past two decades that neuroscience has been established as a recognized discipline where the anatomical, physiological, and chemical aspects of neuronal function are treated in a unified fashion. It can be anticipated that this logical advance'will allow brain research to reach new levels of sophistication. Already it has resulted in the establishment of graduate programs at dozens of universities, and the found ing of numerous journals devoted to reports of interdisciplinary research on the brain.

Brain Development and Behavior

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Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Brain Development and Behavior by : M. B. Sterman

Download or read book Brain Development and Behavior written by M. B. Sterman and published by . This book was released on 1971 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evolution, Early Experience and Human Development

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Publisher : Oxford University Press, USA
ISBN 13 : 0199755051
Total Pages : 508 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Evolution, Early Experience and Human Development by : Darcia Narváez

Download or read book Evolution, Early Experience and Human Development written by Darcia Narváez and published by Oxford University Press, USA. This book was released on 2012-11-29 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cognitive psychology has expanded rapidly in recent years, with experts in affective and cognitive neuroscience revealing more about mammalian brain function than ever before. In contrast, psychological problems such as ADHD, autism, anxiety, and depression are on the rise, as are medical conditions such as diabetes, obesity, and autoimmune disorders. Why, in this era of unprecedented scientific self-knowledge, does there seem to be so much uncertainty about what human beings need for optimal development? Evolution, Early Experience and Human Development asserts that human development is being misshaped by government policies, social practices, and public beliefs that fail to consider basic human needs. In this pioneering volume, scientists from a range of disciplines theorize that the increase in conditions such as depression and obesity can be partially attributed to a disparity between the environments and conditions under which our mammalian brains currently develop and our evolutionary heritage. For example, healthy brain and emotional development depends to a significant extent upon caregiver availability and quality of care. These include practices such as breastfeeding, co-sleeping, and parental social support, which have waned in modern society, but nevertheless may be integral to healthy development. As the authors argue, without a more informed appreciation of the ideal conditions under which human brains/minds develop and function, human beings will continue to struggle with suboptimal mental and physical health, and as problems emerge psychological treatments alone will not be effective. The best approach is to recognize these needs at the outset so as to optimize child development. Evolution, Early Experience and Human Development puts forth a logical, empirically based argument regarding human mammalian needs for optimal development, based on research from anthropology, neurobiology, animal science, and human development. The result is a unique exploration of evolutionary approaches to human behavior that will support the advancement of new policies, new attitudes towards health, and alterations in childcare practices that will better promote healthy human development.

Endogenous Stem Cell-Based Brain Remodeling in Mammals

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Publisher : Springer Science & Business Media
ISBN 13 : 1489973990
Total Pages : 230 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Endogenous Stem Cell-Based Brain Remodeling in Mammals by : Marie-Pierre Junier

Download or read book Endogenous Stem Cell-Based Brain Remodeling in Mammals written by Marie-Pierre Junier and published by Springer Science & Business Media. This book was released on 2014-02-08 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our understanding of ongoing brain development throughout the lifespan and serve to introduce the concept of brain plasticity following injury. The second part is devoted to the endogenous reparative potential of the brain, including its limitations, and articles focusing on defined pathologies (e.g. anoxia/hypoxia, epilepsy, traumatic brain injury and stress) in animal models and in humans pinpoint eventual ways these pathologies might be manipulated. The third and final focuses on the "dark side" of stem cells for brain repair or of the manipulation of spontaneous adaptive events after injury (e.g. genomic instability, sensitization to cancerous transformation and defective neural networks).

Human Brain Evolution

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Publisher : John Wiley & Sons
ISBN 13 : 9780470609873
Total Pages : 232 pages
Book Rating : 4.6/5 (98 download)

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Book Synopsis Human Brain Evolution by : Stephen Cunnane

Download or read book Human Brain Evolution written by Stephen Cunnane and published by John Wiley & Sons. This book was released on 2010-07-30 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolution of the human brain and cognitive ability is one of the central themes of physical/biological anthropology. This book discusses the emergence of human cognition at a conceptual level, describing it as a process of long adaptive stasis interrupted by short periods of cognitive advance. These advances were not linear and directed, but were acquired indirectly as part of changing human behaviors, in other words through the process of exaptation (acquisition of a function for which it was not originally selected). Based on studies of the modem human brain, certain prerequisites were needed for the development of the early brain and associated cognitive advances. This book documents the energy and nutrient constraints of the modern brain, highlighting the significant role of long-chain polyunsaturated fatty acids (LC-PUFA) in brain development and maintenance. Crawford provides further emphasis for the role of essential fatty acids, in particular DHA, in brain development, by discussing the evolution of the eye and neural systems. This is an ideal book for Graduate students, post docs, research scientists in Physical/Biological Anthropology, Human Biology, Archaeology, Nutrition, Cognitive Science, Neurosciences. It is also an excellent selection for a grad student discussion seminar.

Biology of the NMDA Receptor

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Publisher : CRC Press
ISBN 13 : 9781420044157
Total Pages : 350 pages
Book Rating : 4.0/5 (441 download)

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Book Synopsis Biology of the NMDA Receptor by : Antonius M. VanDongen

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.

The Neurobiology of Australian Marsupials

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Publisher : Cambridge University Press
ISBN 13 : 1139492845
Total Pages : 491 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Neurobiology of Australian Marsupials by : Ken Ashwell

Download or read book The Neurobiology of Australian Marsupials written by Ken Ashwell and published by Cambridge University Press. This book was released on 2010-10-14 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Australian marsupials represent a parallel adaptive radiation to that seen among placental mammals. This great natural experiment has produced a striking array of mammals with structural and behavioural features echoing those seen among primates, rodents, carnivores, edentates and ungulates elsewhere in the world. Many of these adaptations involve profound evolutionary changes in the nervous system, and occurred in isolation from those unfolding among placental mammals. Ashwell provides the first comprehensive review of the scientific literature on the structure and function of the nervous system of Australian marsupials. The book also includes the first comprehensive delineated atlases of brain structure in a representative diprotodont marsupial (the tammar wallaby) and a representative polyprotodont marsupial (the stripe-faced dunnart). For those interested in brain development, the book also provides the first comprehensive delineated atlas of brain development in a diprotodont marsupial (the tammar wallaby) during the critical first 4 weeks of pouch life.

The Neurobiology of Childhood

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Author :
Publisher : Springer
ISBN 13 : 3642549136
Total Pages : 368 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis The Neurobiology of Childhood by : Susan L. Andersen

Download or read book The Neurobiology of Childhood written by Susan L. Andersen and published by Springer. This book was released on 2014-05-13 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past years there has been rapid progress in the understanding of how early life stress impacts psychopathology in children. The first two parts of this book present the basic principles of brain development and describe the most important neuronal systems. This includes systems involved in emotion processing, cognitive control, and social processes. These first two general sections are followed by an overview about recent research on various neuronal and psychiatric disorders, where environmental exposures and altered brain development play an important role: sleep, autism, ADHD and other developmental forms of psychopathology.