Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis

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Publisher : Springer Science & Business Media
ISBN 13 : 8847021537
Total Pages : 200 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis by : M. Filippi

Download or read book Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have entered an exciting period in the study of multiple sclerosis and its treatment. Central to this progress has been the introduction of magnetic reso nance techniques. When Young and his colleagues published the first images of the brain in multiple sclerosis at the end of 1981, it was at once obvious that magnetic resonance imaging would playa major role in diagnosis. Intuitively one felt that it would also have a role in increasing our understanding of the pathogenesis of the disease and in monitoring treatment. And so it has proved. Important problems however remain, perhaps the most important of which at present is the weak predictive power of standard magnetic resonance ima ging methods in determining the possibility of progression of impairment and disability. Recently, there have been advances which promise to overcome some of these problems, but decisions about what approach to adopt in selecting patients for clinical trials and which techniques to use in monitoring treatment during their course are still difficult. In this book, Dr. Filippi and his colleagues have assembled an outstanding group of contributors whose work is central to the progress that is being made. The coverage of the issues involved in the use of magnetic resonance techniques in assessing therapeutic effect is comprehensive and, though the field is chan ging rapidly, the principles and much of the detail in the book are likely to have lasting value.

MRI Atlas of MS Lesions

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Publisher : Springer Science & Business Media
ISBN 13 : 3540713719
Total Pages : 184 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis MRI Atlas of MS Lesions by : M.A. Sahraian

Download or read book MRI Atlas of MS Lesions written by M.A. Sahraian and published by Springer Science & Business Media. This book was released on 2007-10-16 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: MRI has become the main paraclinical test in the diagnosis and management of multiple sclerosis. We have demonstrated more than 400 pictures of different typical and atypical MS lesions in this atlas. Each image has a teaching point. New diagnostic criteria and differential diagnosis have been discussed.

Magnetic Resonance Spectroscopy in Multiple Sclerosis

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Publisher : Springer Science & Business Media
ISBN 13 : 884702109X
Total Pages : 180 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Magnetic Resonance Spectroscopy in Multiple Sclerosis by : M. Filippi

Download or read book Magnetic Resonance Spectroscopy in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".

Quantitative Magnetic Resonance Imaging

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Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Magnetic Resonance Imaging in Multiple Sclerosis

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Author :
Publisher : Thieme Medical Publishers
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Magnetic Resonance Imaging in Multiple Sclerosis by : Jürg Kesselring

Download or read book Magnetic Resonance Imaging in Multiple Sclerosis written by Jürg Kesselring and published by Thieme Medical Publishers. This book was released on 1989 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Magnetic Resonance in Multiple Sclerosis

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Publisher : Cambridge University Press
ISBN 13 : 9780521473255
Total Pages : 216 pages
Book Rating : 4.4/5 (732 download)

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Book Synopsis Magnetic Resonance in Multiple Sclerosis by : David H. Miller

Download or read book Magnetic Resonance in Multiple Sclerosis written by David H. Miller and published by Cambridge University Press. This book was released on 1997-07-17 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance (MR) imaging and spectroscopy are powerful tools for demonstrating and monitoring pathological processes of the brain and spinal cord. Multiple sclerosis (MS), a common and as yet incurable disease of the brain and spinal cord, is being studied intensively using these techniques. They perform a major role in facilitating the diagnosis, understanding the mechanisms of symptoms, and monitoring the effect of new treatments. Written by experts in the field, this extensively illustrated text provides a comprehensive review of the benefits and limitations of MR in the study of MS. Coverage ranges through the contributions of MR, the variety of techniques available, diagnosis and differential diagnosis, MR as a predictor of the clinical course, MR views of pathophysiology, and finally monitoring new treatment efficacy.

Magnetic Resonance Imaging of the Brain and Spine

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1469873265
Total Pages : 1872 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis Magnetic Resonance Imaging of the Brain and Spine by : Scott W. Atlas

Download or read book Magnetic Resonance Imaging of the Brain and Spine written by Scott W. Atlas and published by Lippincott Williams & Wilkins. This book was released on 2016-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 25 years, Magnetic Resonance Imaging of the Brain and Spine has been the leading textbook on imaging diagnosis of brain and spine disorders. The Fifth Edition continues this tradition of excellence with thorough coverage of recent trends and changes in the clinical diagnosis and treatment of CNS diseases, and how those changes relate to MRI findings. It remains a comprehensive, state-of-the-art reference for all who have an interest in neuroradiology – trainees to experts in the field, basic science researchers, and clinicians.

New Frontiers of MR-based Techniques in Multiple Sclerosis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 8847022371
Total Pages : 174 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis New Frontiers of MR-based Techniques in Multiple Sclerosis by : Massimo Filippi

Download or read book New Frontiers of MR-based Techniques in Multiple Sclerosis written by Massimo Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.

Contrast-Enhanced Clinical Magnetic Resonance Imaging

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Publisher : University Press of Kentucky
ISBN 13 : 9780813132808
Total Pages : 200 pages
Book Rating : 4.1/5 (328 download)

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Book Synopsis Contrast-Enhanced Clinical Magnetic Resonance Imaging by : Val M. Runge

Download or read book Contrast-Enhanced Clinical Magnetic Resonance Imaging written by Val M. Runge and published by University Press of Kentucky. This book was released on 1997 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MR Imaging in White Matter Diseases of the Brain and Spinal Cord

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540402305
Total Pages : 508 pages
Book Rating : 4.4/5 (23 download)

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Book Synopsis MR Imaging in White Matter Diseases of the Brain and Spinal Cord by : Massimo Filippi

Download or read book MR Imaging in White Matter Diseases of the Brain and Spinal Cord written by Massimo Filippi and published by Springer Science & Business Media. This book was released on 2005-05-09 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases, and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book, written by internationally acclaimed experts, comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research.

Demyelinating Disorders of the Central Nervous System in Childhood

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Publisher : Cambridge University Press
ISBN 13 : 1139496514
Total Pages : 297 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Demyelinating Disorders of the Central Nervous System in Childhood by : Dorothée Chabas

Download or read book Demyelinating Disorders of the Central Nervous System in Childhood written by Dorothée Chabas and published by Cambridge University Press. This book was released on 2011-03-17 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although multiple sclerosis and other disorders of myelin formation and repair are most commonly associated with adults, they can also occur in infants, children and adolescents. Up to 5 percent of those with MS experience symptoms before the age of 18, and the number of cases diagnosed is rising. There is a lack of awareness about these diseases in childhood, however, even amongst pediatric neurologists and MS specialists. Demyelinating Disorders of the Central Nervous System in Childhood provides comprehensive coverage of these diseases, highlighting throughout the differences between management in childhood and in adults. With sections dedicated to the diagnosis, course, treatment and biology of pediatric MS, detailed chapters on other childhood demyelinating diseases, including acute disseminated encephomyelitis, optic neuritis, acute complete transverse myelitis and neuromyelitis optica, are also provided. Essential reading for pediatric neurologists and MS specialists, this book will also be valuable reading for adult neurologists and pediatricians.

Advances in Imaging of Multiple Sclerosis, An Issue of Neuroimaging Clinics of North America, E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323528511
Total Pages : pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Advances in Imaging of Multiple Sclerosis, An Issue of Neuroimaging Clinics of North America, E-Book by : Alex Rovira

Download or read book Advances in Imaging of Multiple Sclerosis, An Issue of Neuroimaging Clinics of North America, E-Book written by Alex Rovira and published by Elsevier Health Sciences. This book was released on 2017-04-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neuroimaging Clinics of North America focuses on Imaging of Multiple Sclerosis: Diagnosis and Management, and is edited by Dr. Àlex Rovira Cañellas. Articles will include: Multiple Sclerosis: Epidemiological, Clinical and Therapeutic Aspects; Brain and Spinal Cord MR Imaging Features in Multiple Sclerosis and Variants; Neuromyelitis Optica Spectrum Disorders; Radiologically Isolated Syndrome; MRI in Monitoring and Predicting Treatment Response in Multiple Sclerosis; Cortical Grey Matter MR Imaging in Multiple Sclerosis; Brain Atrophy in Multiple Sclerosis: Technical Aspects and Clinical Relevance; Iron Mapping in Multiple Sclerosis; Microstructural MR Techniques in Multiple Sclerosis; Molecular and Metabolic Imaging in Multiple Sclerosis; Insights from Ultra-high Field Imaging in Multiple Sclerosis; Pediatric Multiple Sclerosis: Distinguishing Clinical and MRI Features, and more!

Magnetic Resonance Imaging of Neurological Diseases in Tropics

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Publisher : JP Medical Ltd
ISBN 13 : 9350909723
Total Pages : 364 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Magnetic Resonance Imaging of Neurological Diseases in Tropics by : Rakesh K Gupta

Download or read book Magnetic Resonance Imaging of Neurological Diseases in Tropics written by Rakesh K Gupta and published by JP Medical Ltd. This book was released on 2014-01-30 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is a scan that uses strong magnetic fields and radio waves to produce detailed images of the inside of the body. This book is a comprehensive guide to the diagnosis and management of neurological infectious diseases using MRI. Divided into four sections, the text begins with an introduction to tropical diseases of the central nervous system, and their epidemiology. The second section provides in depth coverage of the technique of MRI, from the basic principles, to clinical application and more advanced features. The following sections describe use of the technique for both infectious diseases, including tuberculosis, HIV and parasitic diseases; and noninfectious conditions, such as stroke, poisoning and epilepsy. Each chapter features numerous MRI and pathological images and extensive references. Key points Comprehensive guide to diagnosis and management of neurological infectious diseases in tropics using MRI In depth coverage of the technique, from basics to more advanced aspects Covers MRI for both infectious and noninfectious conditions Includes nearly 300 MRI and pathological images

High Field Brain MRI

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Publisher : Springer Science & Business Media
ISBN 13 : 3540317767
Total Pages : 248 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis High Field Brain MRI by : Ugo Salvolini

Download or read book High Field Brain MRI written by Ugo Salvolini and published by Springer Science & Business Media. This book was released on 2006-06-23 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the development of systems of magnetic resonance imaging using the higher magnetic field strength of 3 tesla, in comparison to the current gold standard of 1.5 tesla. These new systems of MRI make it possible to perform with high spatial, temporal and contrast resolution not only morphological examinations but also functional studies on spectroscopy, diffusion, perfusion, and cortical activation, thus helping research and providing an important tool for routine diagnostic activity. At the same time the new systems offer unparalleled sensitivity and specificity in the numerous conditions of neuroradiological interest.

Neurological Disorders and Imaging Physics

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Publisher :
ISBN 13 : 9780750317597
Total Pages : 0 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Neurological Disorders and Imaging Physics by : Jasjit S. Suri

Download or read book Neurological Disorders and Imaging Physics written by Jasjit S. Suri and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a disease where the body's immune system attacks the brain and spinal cord, causing debilitating side effects that last a lifetime for those affected. Magnetic resonance imaging (MRI) has become an established tool in the diagnosis and monitoring of MS due to its ability to depict the pathological features of the disease in high detail. Over the past few decades, developments in MRI applications, and MRI-based visualization of demyelinated CNS lesions have become pivotal to the diagnosis and monitoring of MS. In recent years, newer MR imaging technologies, including higher-field-strength MR units, have been developed to analyse the overall MS damage and highlight potential mechanisms of recovery in patients at different stages of the disease.

Normal-appearing White and Grey Matter Damage in Multiple Sclerosis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 8847021278
Total Pages : 184 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Normal-appearing White and Grey Matter Damage in Multiple Sclerosis by : M. Filippi

Download or read book Normal-appearing White and Grey Matter Damage in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years, increasing effort has been devoted to better define the characteristics of tissue damage occurring outside MRI-visible lesions in patients with multiple sclerosis (MS) and, as a consequence, to improve our understanding of the disease pathobiology and of the mechanisms leading to the accumulation of irreversible disability. This book provides an updated review of the results obtained by leading research groups in this field. The potential clinical applications of what has been shown so far, as well as the areas for future research in the study of normal-appearing white and gray matter damage in MS are extensively discussed, making this book a valuable tool for clinical neurologists who are involved in the daily-life care of MS patients and for neuroscientists involved in MS research.

Neurological Disorders and Imaging Physics

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Publisher :
ISBN 13 : 9780750317580
Total Pages : pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Neurological Disorders and Imaging Physics by : Jasjit S. Suri

Download or read book Neurological Disorders and Imaging Physics written by Jasjit S. Suri and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a disease where the body's immune system attacks the brain and spinal cord, causing debilitating side effects that last a lifetime for those affected. Magnetic resonance imaging (MRI) has become an established tool in the diagnosis and monitoring of MS due to its ability to depict the pathological features of the disease in high detail. Over the past few decades, developments in MRI applications, and MRI-based visualization of demyelinated CNS lesions have become pivotal to the diagnosis and monitoring of MS. In recent years, newer MR imaging technologies, including higher-field-strength MR units, have been developed to analyse the overall MS damage and highlight potential mechanisms of recovery in patients at different stages of the disease.