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Author : Ying Ding (Ph. D.)
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (828 download)
Download or read book Magnetic Resonance Diffusion Characterization of Brain Diseases written by Ying Ding (Ph. D.) and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ying Ding
Publisher : Open Dissertation Press
ISBN 13 : 9781361304877
Total Pages : pages
Book Rating : 4.3/5 (48 download)
Download or read book Magnetic Resonance Diffusion Characterization of Brain Diseases written by Ying Ding and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Magnetic Resonance Diffusion Characterization of Brain Diseases" by 丁莹, Ying, Ding, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Magnetic resonance imaging (MRI) is a valuable imaging technique. It provides excellent soft tissue contrast and multi-parametric non-invasive imaging protocols. Among those various techniques, diffusion MRI measures the water diffusion properties of biological tissue. It is a useful tool in characterizing various brain tissue microstructures quantitatively. With its rapid development, it is emerging that subtle changes can be probed by diffusion tensor imaging (DTI) quantitation. The objectives of this doctoral work are to access the subtle microstructural alterations in rodent brains due to hemodynamic changes, fear conditioning and sleep deprivation using in vivo DTI. With the improved reproducibility and specificity achieved by using advanced post-processing and animal preparation procedures, in vivo DTI is expected to be useful to explore the underlying biological mechanisms for posttraumatic stress disorder and memory deficit following sleep loss in human. Firstly, as DTI could be influenced by the presence of water molecules in brain vasculature, for better understand the reproducibility and sensitivity of in vivo DTI measurements, conventional DTI protocol was applied to a well-controlled rat model of hypercapnia. Our data demonstrated that diffusivities increased in whole brain, gray and white matter regions in response to hypercapnia. These results indicate that in vivo DTI quantitation in brain can be interfered by vascular factors on the order of few percents. Cautions should be taken in designing and interpreting quantitative DTI studies as all DTI indices can be potentially confounded by physiologic conditions, cerebrovascular and hemodynamic characteristics. Secondly, recent DTI studies have shown detection of long-term neural plasticity weeks to months following relatively extensive periods of training in animals. However, rapid plasticity within a short period (24 hours) after learning is important for observing the time course of training-evoked changes and narrow down candidate mechanisms. Fear conditioning (FC), which typically occurs over a short timescale (in minutes), was selected as a paradigm for investigation. Using voxel-wise repeated measures analysis, FA was found to increase in amygdala and decrease in hippocampus 1-hour post-FC, and it reversed in both regions 1-day post-FC. Results indicate that DTI can detect rapid microstructural changes in brain regions known to mediate fear conditioning in vivo. DTI indices could be explored as a translational tool to capture potential early biological changes in individuals at risk for developing post-traumatic stress disorder. Thirdly, in vivo DTI was employed to access regional specific microstructural changes following rapid eye movement sleep deprivation (SD), and explore possible temporal differentiation of these changes. With voxel-base analysis, MD is found to decrease in post-SD time points in bilateral hippocampi and cerebral cortex. The distributions of these clusters exhibited differentiable layer specific patterns, which were pointing to dentate gyrus and CA1 layer in hippocampus, and parietal cortex and barrel field layers in cerebral cortex. Results indicate that in vivo DTI is capable to detect microstructural changes in specific layers and reveal temporal distinction between them. These specific layers are possibly more susceptible to sleep loss, and the temporal distinction of changes between these
Author : Yang Ding (Ph. D.)
Publisher :
ISBN 13 :
Total Pages : 93 pages
Book Rating : 4.:/5 (828 download)
Download or read book Magnetic Resonance Diffusion Characterization of Brain Diseases written by Yang Ding (Ph. D.) and published by . This book was released on 2012 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xuan Gu
Publisher : Linköping University Electronic Press
ISBN 13 : 9175190036
Total Pages : 93 pages
Book Rating : 4.1/5 (751 download)
Download or read book Advanced analysis of diffusion MRI data written by Xuan Gu and published by Linköping University Electronic Press. This book was released on 2019-11-19 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion magnetic resonance imaging (diffusion MRI) is a non-invasive imaging modality which can measure diffusion of water molecules, by making the MRI acquisition sensitive to diffusion. Diffusion MRI provides unique possibilities to study structural connectivity of the human brain, e.g. how the white matter connects different parts of the brain. Diffusion MRI enables a range of tools that permit qualitative and quantitative assessments of many neurological disorders, such as stroke and Parkinson. This thesis introduces novel methods for diffusion MRI data analysis. Prior to estimating a diffusion model in each location (voxel) of the brain, the diffusion data needs to be preprocessed to correct for geometric distortions and head motion. A deep learning approach to synthesize diffusion scalar maps from a T1-weighted MR image is proposed, and it is shown that the distortion-free synthesized images can be used for distortion correction. An evaluation, involving both simulated data and real data, of six methods for susceptibility distortion correction is also presented in this thesis. A common problem in diffusion MRI is to estimate the uncertainty of a diffusion model. An empirical evaluation of tractography, a technique that permits reconstruction of white matter pathways in the human brain, is presented in this thesis. The evaluation is based on analyzing 32 diffusion datasets from a single healthy subject, to study how reliable tractography is. In most cases only a single dataset is available for each subject. This thesis presents methods based on frequentistic (bootstrap) as well as Bayesian inference, which can provide uncertainty estimates when only a single dataset is available. These uncertainty measures can then, for example, be used in a group analysis to downweight subjects with a higher uncertainty.
Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author : Federico Giove
Publisher : Frontiers Media SA
ISBN 13 : 2889455548
Total Pages : 150 pages
Book Rating : 4.8/5 (894 download)
Download or read book Proceedings of the International School on Magnetic Resonance and Brain Function - XII Workshop written by Federico Giove and published by Frontiers Media SA. This book was released on 2018-09-06 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last thirty years, Magnetic Resonance has generated a wide revolution in biomedical research and in medical imaging in general. More recently, the "in vivo" studies of the human brain were extended by new original ways to the dynamic study of function and metabolism of the human brain. The enormous interest in expanding the investigation of the brain is emphasizing the search for new NMR methods capable of extracting information of so-far obscure aspects of the brain function. In fact, many quantitative approaches have been proposed in order to complement the information obtained by functional MRI, and several multimodal and multiparametric approaches have been developed to exploit the information, either functional or structural, made available by the flexible contrast generation typical of MRI, and to combine it with complementary information. The XII workshop of the International School on Magnetic Resonanceand Brain Function, held in Erice between 17 April and 6 May, 2016, was specially devoted to novel approaches aimed at better structural characterization of brain diseases, and at investigating frontiers MRI approaches to better understand the brain function. The papers included in this eBook offer a broad overview of the subjects covered during the Workshop, including applications of multiparametric MRI to neurological diseases, multimodal combination of MRI with electrophysiology, advanced methods for the investigation of brain networks and of brain physiology, and perspectives towards brain state reading.
Author : Moo K. Chung
Publisher : Cambridge University Press
ISBN 13 : 110718486X
Total Pages : 343 pages
Book Rating : 4.1/5 (71 download)
Download or read book Brain Network Analysis written by Moo K. Chung and published by Cambridge University Press. This book was released on 2019-06-27 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.
Author : Heidi Johansen-Berg
Publisher : Academic Press
ISBN 13 : 0124055095
Total Pages : 627 pages
Book Rating : 4.1/5 (24 download)
Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout
Author : Jörg Polzehl
Publisher : Springer Nature
ISBN 13 : 3030291847
Total Pages : 231 pages
Book Rating : 4.0/5 (32 download)
Download or read book Magnetic Resonance Brain Imaging written by Jörg Polzehl and published by Springer Nature. This book was released on 2019-09-25 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the modeling and analysis of magnetic resonance imaging (MRI) data acquired from the human brain. The data processing pipelines described rely on R. The book is intended for readers from two communities: Statisticians who are interested in neuroimaging and looking for an introduction to the acquired data and typical scientific problems in the field; and neuroimaging students wanting to learn about the statistical modeling and analysis of MRI data. Offering a practical introduction to the field, the book focuses on those problems in data analysis for which implementations within R are available. It also includes fully worked examples and as such serves as a tutorial on MRI analysis with R, from which the readers can derive their own data processing scripts. The book starts with a short introduction to MRI and then examines the process of reading and writing common neuroimaging data formats to and from the R session. The main chapters cover three common MR imaging modalities and their data modeling and analysis problems: functional MRI, diffusion MRI, and Multi-Parameter Mapping. The book concludes with extended appendices providing details of the non-parametric statistics used and the resources for R and MRI data.The book also addresses the issues of reproducibility and topics like data organization and description, as well as open data and open science. It relies solely on a dynamic report generation with knitr and uses neuroimaging data publicly available in data repositories. The PDF was created executing the R code in the chunks and then running LaTeX, which means that almost all figures, numbers, and results were generated while producing the PDF from the sources.
Author : Jörg Polzehl
Publisher : Springer Nature
ISBN 13 : 3031389492
Total Pages : 268 pages
Book Rating : 4.0/5 (313 download)
Download or read book Magnetic Resonance Brain Imaging written by Jörg Polzehl and published by Springer Nature. This book was released on 2023-11-12 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses modelling and analysis of Magnetic Resonance Imaging (MRI) data of the human brain. For the data processing pipelines we rely on R, the software environment for statistical computing and graphics. The book is intended for readers from two communities: Statisticians, who are interested in neuroimaging and look for an introduction to the acquired data and typical scientific problems in the field and neuroimaging students, who want to learn about the statistical modeling and analysis of MRI data. Being a practical introduction, the book focuses on those problems in data analysis for which implementations within R are available. By providing full worked-out examples the book thus serves as a tutorial for MRI analysis with R, from which the reader can derive its own data processing scripts. The book starts with a short introduction into MRI. The next chapter considers the process of reading and writing common neuroimaging data formats to and from the R session. The main chapters then cover four common MR imaging modalities and their data modeling and analysis problems: functional MRI, diffusion MRI, Multi-Parameter Mapping and Inversion Recovery MRI. The book concludes with extended Appendices on details of the utilize non-parametric statistics and on resources for R and MRI data. The book also addresses the issues of reproducibility and topics like data organization and description, open data and open science. It completely relies on a dynamic report generation with knitr: The books R-code and intermediate results are available for reproducibility of the examples.
Author : Lara A. Brandao
Publisher : Elsevier Health Sciences
ISBN 13 : 1455772011
Total Pages : 549 pages
Book Rating : 4.4/5 (557 download)
Download or read book Modern Imaging Evaluation of the Brain, Body and Spine, An Issue of Magnetic Resonance Imaging Clinics written by Lara A. Brandao and published by Elsevier Health Sciences. This book was released on 2013-05-28 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy (MRS) is an analytical method used in chemistry that enables the identification and quantification of metabolites in samples. It differs from conventional Magnetic Resonance Imaging in that spectra provide physiological and chemical information instead of anatomy. This issue examines MRS methods for a wide variety of body imaging needs.
Author : Yong He
Publisher : Frontiers Media SA
ISBN 13 : 2889194353
Total Pages : 366 pages
Book Rating : 4.8/5 (891 download)
Download or read book Magnetic Resonance Imaging of Healthy and Diseased Brain Networks written by Yong He and published by Frontiers Media SA. This book was released on 2015-03-05 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important aspect of neuroscience is to characterize the underlying connectivity patterns of the human brain (i.e., human connectomics). Over the past few years, researchers have demonstrated that by combining a variety of different neuroimaging technologies (e.g., structural MRI, diffusion MRI and functional MRI) with sophisticated analytic strategies such as graph theory, it is possible to noninvasively map the patterns of structural and functional connectivity of human whole-brain networks. With these novel approaches, many studies have shown that human brain networks have nonrandom properties such as modularity, small-worldness and highly connected hubs. Importantly, these quantifiable network properties change with age, learning and disease. Moreover, there is growing evidence for behavioral and genetic correlates. Network analysis of neuroimaging data is opening up a new avenue of research into the understanding of the organizational principles of the brain that will be of interest for all basic scientists and clinical researchers. Such approaches are powerful but there are a number of challenging issues when extracting reliable brain networks from various imaging modalities and analyzing the topological properties, e.g., definitions of network nodes and edges and reproducibility of network analysis. We assembled contributions related to the state-of-the-art methodologies of brain connectivity and the applications involving development, aging and neuropsychiatric disorders such as Alzheimer’s disease, schizophrenia, attention deficit hyperactivity disorder and mood and anxiety disorders. It is anticipated that the articles in this Research Topic will provide a greater range and depth of provision for the field of imaging connectomics.
Author : Jay J. Pillai
Publisher : Springer Science & Business Media
ISBN 13 : 1441958584
Total Pages : 253 pages
Book Rating : 4.4/5 (419 download)
Download or read book Functional Brain Tumor Imaging written by Jay J. Pillai and published by Springer Science & Business Media. This book was released on 2013-10-16 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Imaging of Brain Tumors is a unique resource that serves to advance patient care and research in this rapidly developing field.
Author : Paul Tofts
Publisher : John Wiley & Sons
ISBN 13 : 9780470847213
Total Pages : 678 pages
Book Rating : 4.8/5 (472 download)
Download or read book Quantitative MRI of the Brain written by Paul Tofts and published by John Wiley & Sons. This book was released on 2003 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 'how to' manual of quantitative MR, essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological diseases, its progression and its response to treatment. It is also designed for research-minded radiologists, neurologists and MRI physicists who are considering undertaking quantitative work, as well as those already in the field.
Author : Kathline Swift
Publisher : American Medical Publishers
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (874 download)
Download or read book Neuroimaging for the Characterization of Brain Disorders written by Kathline Swift and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimaging refers to the utilization of quantitative methods for the study of the structure and function of the central nervous system. It was developed as a non-invasive method to scientifically investigate the healthy human brain. It is widely being used in quantitative investigations for psychiatric illnesses and brain disorders. Various techniques that are used in neuroimaging include computed axial tomography and magnetic resonance imaging, diffuse optical imaging, positron emission tomography, cranial ultrasound. The human brain is a massive, interconnected and complex system. Advanced neuroimaging techniques such as diffusion tensor imaging and functional magnetic resonance imaging allow us to investigate the underlying principles of brain structural and functional architectures. It also enables us to study the pathological changes in a variety of brain disorders. Multi-modal neuroimaging techniques could provide a more thorough understanding of the pathomechanism of brain disorders, which facilitates early diagnosis and helps in assessing prognosis and therapeutic effect. This book elucidates the concepts and innovative models around prospective developments with respect to the characterization of brain disorders. The topics covered herein offer the readers new insights in the field of neuroimaging.
Author : Claudia Leite
Publisher : Thieme
ISBN 13 : 1638530653
Total Pages : 466 pages
Book Rating : 4.6/5 (385 download)
Download or read book Diffusion Weighted and Diffusion Tensor Imaging written by Claudia Leite and published by Thieme. This book was released on 2015-12-16 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion-weighted imaging (DWI) is an integral part of routine neuroimaging, used nearly universally in brain MRIs, and more recently for the spine, spinal cord, and head and neck. DWI provides clinically relevant information on conditions including stroke, infection, and neoplasms. Diffusion tensor imaging (DTI) is a powerful, newer technique with the potential for multiple protocols, including the diagnosis of mild traumatic brain injury and psychiatric disorders. Written by leading authorities in neuroradiology and radiology, Diffusion Weighted and Diffusion Tensor Imaging: A Clinical Guide provides key points and summaries on the concepts and applications required for proper implementation and interpretation of DWI and DTI. Key Features: More than 600 high-quality illustrations Protocols and applications from early childhood to older adulthood Methods to differentiate normal versus pathological states Brain edema pathophysiology and use of DWI to distinguish between cytotoxic and vasogenic edema Utilization of DWI and DTI to diagnose trauma, white matter disease, tumors, cerebrovascular disease, and head, neck, and spine disorders This concise handbook is an invaluable resource for neuro-radiologists and radiologists, as well as fellows and residents in these disciplines. With the expanding use of these procedures, neuroscientists, neurologists, neurosurgeons, and psychiatrists will also find it indispensable.
Author : Herbert B. Newton
Publisher : Academic Press
ISBN 13 : 0128229950
Total Pages : 1022 pages
Book Rating : 4.1/5 (282 download)
Download or read book Handbook of Neuro-Oncology Neuroimaging written by Herbert B. Newton and published by Academic Press. This book was released on 2022-08-21 with total page 1022 pages. Available in PDF, EPUB and Kindle. Book excerpt: With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. Summarizes translational research on brain imaging for brain tumors Discusses limitations of neuroimaging for diagnosis and treatment Presents advanced imaging technologies, including CT, MRI, and PET Contains new coverage on Laser Interstitial Thermal Therapy, radiation therapy, clinical trials, and more
