Local Hepatic Therapies For Metastases To The Liver From Unresectable Colorectal Cancer

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Colorectal Cancer Liver Metastases

Author : Mauro Monteiro Correia
Publisher : Springer Nature
ISBN 13 : 3030254860
Total Pages : 597 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Colorectal Cancer Liver Metastases by : Mauro Monteiro Correia

Download or read book Colorectal Cancer Liver Metastases written by Mauro Monteiro Correia and published by Springer Nature. This book was released on 2019-12-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.

Local Hepatic Therapies for Metastases to the Liver from Unresectable Colorectal Cancer

Author : U. S. Department of Health and Human Services
Publisher : Createspace Independent Pub
ISBN 13 : 9781483955865
Total Pages : 186 pages
Book Rating : 4.9/5 (558 download)

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Book Synopsis Local Hepatic Therapies for Metastases to the Liver from Unresectable Colorectal Cancer by : U. S. Department of Health and Human Services

Download or read book Local Hepatic Therapies for Metastases to the Liver from Unresectable Colorectal Cancer written by U. S. Department of Health and Human Services and published by Createspace Independent Pub. This book was released on 2013-03-25 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report aims to compare the effectiveness and harms of several local hepatic therapies for unresectable colorectal cancer (CRC) metastases to the liver. In this report, we describe CRC and its diagnosis and treatment to orient the reader to the disease. This is followed by a discussion of the treatment of CRC liver metastasis. CRC is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. It is a cancer that forms in the tissues of the colon and the rectum. Most colorectal cancers are adenocarcinomas, meaning that they are a cancer of the epithelium originating from glandular tissue. Adenocarcinomas develop from adenomas, which are noncancerous tumors in the epithelial tissue. Over time, adenomas can become cancerous. This progression from adenoma to adenocarcinoma occurs through a sequential process of accumulating genetic changes. Although the most common type of CRC is adenocarcinoma, squamous carcinoma and adenosquamous carcinoma have been reported infrequently.An elevated risk of CRC has been associated with obesity, low physical activity, high dietary intake of refined sugars, low dietary intake of fiber, consumption of meat, and consumption of more than two alcoholic drinks per day. A reduction in risk has been linked to the intake of dietary calcium and diets high in fiber and potassium. The objective of this systematic review is to characterize the comparative effectiveness and harms of various local hepatic therapies for liver metastases from unresectable CRC in two distinct patient populations: Patients with unresectable, liver-dominant (i.e., majority of disease located in the liver) metastases who are not eligible for continued systemic chemotherapy because their disease is refractory (i.e., they have experienced disease progression while on therapy); Patients who are candidates for local liver therapies as an adjunct to systemic chemotherapy. There is extensive uncertainty surrounding the optimal use of the various local hepatic therapies. Because of the prevalence of CRC and the high likelihood of metastases, especially to the liver, this topic is important to health care providers, patients, and policymakers. We addressed four Key Questions (KQs) for the two patient populations described above: KQ1. What is the comparative effectiveness of the various liver-directed therapies in patients whose disease is refractory to systemic therapy for unresectable CRC metastases to the liver and who have minimal evidence of extrahepatic disease? KQ2. What are the comparative harms of the various liver-directed therapies in patients whose disease is refractory to systemic therapy for unresectable CRC metastases to the liver and who have minimal evidence of extrahepatic disease? KQ3. What is the comparative effectiveness of the various liver-directed therapies in patients who are candidates for local hepatic therapy as an adjunct to systemic therapy for unresectable CRC metastases to the liver and have no evidence of extrahepatic disease? KQ4. What are the comparative harms of the various liver-directed therapies in patients who are candidates for local hepatic therapy as an adjunct to systemic therapy for unresectable CRC metastases to the liver and have no evidence of extrahepatic disease?

Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer by :

Download or read book Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer written by and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Management and Therapy

Author : Amal Hamza
Publisher : BoD – Books on Demand
ISBN 13 : 1789232988
Total Pages : 212 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Cancer Management and Therapy by : Amal Hamza

Download or read book Cancer Management and Therapy written by Amal Hamza and published by BoD – Books on Demand. This book was released on 2018-06-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters.

Perioperative Chemotherapy

Author : U. Metzger
Publisher : Springer Science & Business Media
ISBN 13 : 3642824323
Total Pages : 170 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Perioperative Chemotherapy by : U. Metzger

Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

Preoperative (Neoadjuvant) Chemotherapy

Author : Joseph Ragaz
Publisher : Springer Science & Business Media
ISBN 13 : 3642826717
Total Pages : 172 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz

Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Rectal Cancer Treatment

Author : M.W. Büchler
Publisher : Springer Science & Business Media
ISBN 13 : 3540274499
Total Pages : 284 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Rectal Cancer Treatment by : M.W. Büchler

Download or read book Rectal Cancer Treatment written by M.W. Büchler and published by Springer Science & Business Media. This book was released on 2005-10-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.

Extreme Hepatic Surgery and Other Strategies

Author : Eduardo de Santibañes
Publisher : Springer
ISBN 13 : 3319138960
Total Pages : 383 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Extreme Hepatic Surgery and Other Strategies by : Eduardo de Santibañes

Download or read book Extreme Hepatic Surgery and Other Strategies written by Eduardo de Santibañes and published by Springer. This book was released on 2017-07-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.

Immunotherapy of Hepatocellular Carcinoma

Author : Tim F. Greten
Publisher : Springer
ISBN 13 : 3319649582
Total Pages : 167 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Immunotherapy of Hepatocellular Carcinoma by : Tim F. Greten

Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2017-10-04 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Radiation Therapy for Liver Tumors

Author : Jeffrey Meyer
Publisher : Springer
ISBN 13 : 3319545310
Total Pages : 288 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Radiation Therapy for Liver Tumors by : Jeffrey Meyer

Download or read book Radiation Therapy for Liver Tumors written by Jeffrey Meyer and published by Springer. This book was released on 2017-07-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of liver tumors is a nexus of interactions among multiple medical specialties, including radiation oncology. A multitude of liver-directed therapies are available for patients, ranging from surgery and liver transplantation to intra-arterial therapies, thermal ablation procedures, systemic therapies, and radiation treatments. With the introduction of hypofractionated irradiation, particle therapy, and radioembolization, there is growing interest in the use of radiation as a treatment for liver malignancies. This book examines basic principles of the management of liver tumors. The evolving roles of x-ray and particle therapies as well as radioembolization in the treatment of liver tumors is the main focus. A theme of multidisciplinary management is also emphasized, as surgical, interventional and systemic therapies are reviewed. A unique resource that discusses the role of radiation treatment in the context of other liver-directed therapies, Radiation Therapy for Liver Tumors is of broad interest to radiation oncologists, surgeons, hepatologists, medical oncologists, and radiologists.

Treatment of Soft Tissue Sarcomas

Author : H.M. Pinedo
Publisher : Springer Science & Business Media
ISBN 13 : 1461317576
Total Pages : 143 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Treatment of Soft Tissue Sarcomas by : H.M. Pinedo

Download or read book Treatment of Soft Tissue Sarcomas written by H.M. Pinedo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major advances of the last decade concerning the treatment of patients with soft tissue sarcomas is that an increased number of patients are being discussed in multidisciplinary teams prior to the initial treatment. The present volume on soft tissue sarcomas in the series Cancer Treatment and Research reflects the multidisciplinary approach with a focus on recent developments. The availability of new histopathologic techniques has reduced the number of unclassified sarcomas and has furhter increased the importance of the histo pathologist in providing estimates of the prognosis of the patient as well as data for the planning of treatment strategy. Further data for this strategy will be provided by diagnostic imaging. In this field, the role of magnetic reson ance imaging has been further defined. Of utmost importance is the recent trend toward consensus in staging. The modification of the staging system of the American Joint Commission for Cancer Staging and End Results Report ing brings the possibility of a single staging system within reach in the next decade. As surgery still provides the only chance for cure, the importance of being the most sparing as possible is obvious. For this reason, radiotherapy has been applied with success. The introduction of relatively new radiation tech niques is therefore being observed with interest.

Encyclopedia of Cancer

Author : Manfred Schwab
Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Cancer by : Manfred Schwab

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

Local Therapies for Unresectable Primary Hepatocellular Carcinoma

Author : U. S. Department of Health and Human Services
Publisher : CreateSpace
ISBN 13 : 9781491081099
Total Pages : 330 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Local Therapies for Unresectable Primary Hepatocellular Carcinoma by : U. S. Department of Health and Human Services

Download or read book Local Therapies for Unresectable Primary Hepatocellular Carcinoma written by U. S. Department of Health and Human Services and published by CreateSpace. This book was released on 2013-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comparative effectiveness review evaluates local hepatic therapies for patients with unresectable primary hepatocellular carcinoma (HCC) who are not candidates for surgical resection or liver transplantation. Here we describe the epidemiology and staging of HCC, as well as currently available treatment strategies. We also discuss the current practice guidelines and the impetus for this review. Hepatocellular carcinoma is the most common primary liver tumor. It is the fifth most common cancer and the third leading cause of cancer death worldwide. Overall 5-year survival rates for HCC are less than 10 percent in Europe and the United States. The main etiology of HCC is chronic infection with the hepatitis B and hepatitis C viruses. Approximately 4 million individuals in the United States are chronically infected with hepatitis C virus, and the annual incidence rate of HCC among patients with hepatitis C–related cirrhosis is estimated to be between 2 and 8 percent. Unlike the case with most solid tumors, the incidence of and mortality rate due to HCC are projected to increase worldwide in the next 20 years, primarily due to the dissemination of hepatitis C virus infection.Other causes include cirrhosis due to any cause (e.g., alcohol), hereditary hemochromatosis and iron overload syndromes, nonalcoholic fatty liver disease, obesity, diabetes, and environmental toxins (e.g., aflatoxin, chewing of betel quid, and contaminated water). While there are several causes of HCC, etiology is not an independent prognostic factor for HCC; rather, the underlying cirrhosis impacts prognosis and treatment decisions. In the United States, most cases of HCC occur in patients with cirrhosis.1A small proportion, approximately 5 percent, of all HCC cases in Western countries occur in patients without cirrhosis. For patients with early-stage HCC without underlying cirrhosis, surgical resection is the preferred treatment and offers a high probability of a cure. The Barcelona Clinic Liver Cancer (BCLC) guidelines recommend hepatectomy for patients with a single lesion less than 5 cm in size and mild or no underlying cirrhosis. In contrast, patients with severe cirrhosis are not considered resectable and receive supportive care instead. This report focuses on the approximately 80 percent of patients who are not surgical candidates due to advanced-stage disease at diagnosis, inadequate hepatic reserve to tolerate resection, tumors in unresectable locations, or medical comorbidities that result in a high surgical risk. The following are the Key Questions (KQs) addressed in this review. KQ1. What is the comparative effectiveness of the various liver-directed therapies in patients with HCC who are not otherwise candidates for surgical resection or transplantation with no evidence of extrahepatic disease regarding survival and quality of life? KQ2. What are the comparative harms of the various liver-directed therapies in patients with HCC who are not otherwise candidates for surgical resection or transplantation with no evidence of extrahepatic disease regarding adverse events? KQ3. Are there differences in comparative effectiveness of various liver-directed therapies in patients with HCC who are not otherwise candidates for surgical resection or transplantation for specific patient and tumor characteristics, such as age, gender, disease etiology, and Child-Pugh score?

Liver-Directed Therapy for Primary and Metastatic Liver Tumors

Author : Mark S. Talamonti
Publisher : Springer Science & Business Media
ISBN 13 : 9780792375234
Total Pages : 342 pages
Book Rating : 4.3/5 (752 download)

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Book Synopsis Liver-Directed Therapy for Primary and Metastatic Liver Tumors by : Mark S. Talamonti

Download or read book Liver-Directed Therapy for Primary and Metastatic Liver Tumors written by Mark S. Talamonti and published by Springer Science & Business Media. This book was released on 2001-11-30 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique multi-modality approach to management of all types of primary and secondary liver tumors. The biology of liver cancers, state of the art radiologic imaging and novel, non-surgical interventional strategies are given. There is an in depth analysis of surgical options including transplantation, resection, interstitial ablation techniques and liver-directed chemotherapy for hepatocellular carcinoma, bile duct cancers, and colorectal and neuroendocrine liver metastases. Because of the unique and comprehensive examination of liver tumors, this work is an excellent resource for surgical, transplant and medical oncologists, surgeons, gastroenterologists, and radiologists.

Management of Metastatic Liver Tumors, An Issue of Surgical Oncology Clinics of North America, E-Book

Author : Michael D'Angelica
Publisher : Elsevier Health Sciences
ISBN 13 : 0323764509
Total Pages : 241 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Management of Metastatic Liver Tumors, An Issue of Surgical Oncology Clinics of North America, E-Book by : Michael D'Angelica

Download or read book Management of Metastatic Liver Tumors, An Issue of Surgical Oncology Clinics of North America, E-Book written by Michael D'Angelica and published by Elsevier Health Sciences. This book was released on 2020-12-02 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has assembled expert authors to review the following topics: Surgical management of liver metastases of colorectal cancer; Surgical management of liver metastases of breast cancer; Surgical management of liver metastases of neuroendocrine tumors; Surgical management of liver metastases of sarcoma (including GIST); Surgical management of liver metastases of gynecologic cancers; Surgical management of liver metastases of genitourinary cancers; Surgical management of liver metastases of uveal and dermal melanoma; Is there a role for locoregional therapies for non-colorectal GI malignancies?; Intra-arterial chemotherapy for liver metastases; External beam radiation for liver metastases; Isolated hepatic perfusion for liver metastases; Debate: Improvements in systemic therapies for liver metastases will soon render locoregional treatments obsolete; Debate: Improvements in systemic therapies for liver metastases will increase the role of locoregional treatments; and more!

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

Author : Arthur Zimmermann
Publisher : Springer
ISBN 13 : 9783319269542
Total Pages : 0 pages
Book Rating : 4.2/5 (695 download)

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Book Synopsis Tumors and Tumor-Like Lesions of the Hepatobiliary Tract by : Arthur Zimmermann

Download or read book Tumors and Tumor-Like Lesions of the Hepatobiliary Tract written by Arthur Zimmermann and published by Springer. This book was released on 2016-11-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all liver tumors and lesions that clinically and radiologically mimic liver tumors. It provides readers with a comprehensive overview of this complex and rapidly evolving field. All aspects of surgical pathology are addressed, supplemented by detailed presentations of the lesions’ cell-biologic and molecular features. In addition, the methods employed for diagnosis and diagnostic algorithms are discussed. It appeals to pathologists and hepatologists and serves as an invaluable aid to diagnosis.The field of liver tumors and tumor-like lesions in adults and children has experienced tremendous advances in recent years. Specifically, the recognition of novel entities, deepened insights into known tumors, and refinement of classifications have necessitated continual updates and reappraisals. In addition, previous understanding of hepatic carcinogenesis and tumor progression has been transformed by the very rapid evolution of our understanding of cell biology, genomics, signaling pathways, cell interactions, and mechanisms of invasion and spread of hepatic tumor cells. These general pathology issues must be combined with surgical pathology if a comprehensive understanding of liver tumor pathology is to be achieved.

Liver Malignancies

Author : C. Bartolozzi
Publisher : Springer Science & Business Media
ISBN 13 : 3642586414
Total Pages : 534 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Liver Malignancies by : C. Bartolozzi

Download or read book Liver Malignancies written by C. Bartolozzi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver malignancies. Following background chapters on anatomy, epidemiology, and clinicopathologic features, each of the diagnostic imaging techniques is carefully appraised, focusing on new developments in equipment and contrast agents. The interventional therapeutic approaches to primary and secondary hepatic malignancies are then discussed in depth, as well as such special topics as liver tumors in children and hepatic transplantation. Written by leading experts from around the world, this will prove to be an indispensable source of information for both clinicians and researchers.