Perioperative Chemotherapy

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Perioperative Chemotherapy

Author : U. Metzger
Publisher : Springer Science & Business Media
ISBN 13 : 3642824323
Total Pages : 170 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Perioperative Chemotherapy by : U. Metzger

Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

Preoperative (Neoadjuvant) Chemotherapy

Author : Joseph Ragaz
Publisher : Springer Science & Business Media
ISBN 13 : 3642826717
Total Pages : 172 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz

Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Preoperative (Neoadjuvant) Chemotherapy

Author : Joseph Ragaz
Publisher : Springer
ISBN 13 : 9783642826733
Total Pages : 0 pages
Book Rating : 4.8/5 (267 download)

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Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz

Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer. This book was released on 2012-03-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Cytoreductive Surgery and Perioperative Chemotherapy for Peritoneal Surface Malignancy

Author : Marcello Deraco
Publisher : Cine Med, Incorporated
ISBN 13 : 9780984617159
Total Pages : 214 pages
Book Rating : 4.6/5 (171 download)

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Book Synopsis Cytoreductive Surgery and Perioperative Chemotherapy for Peritoneal Surface Malignancy by : Marcello Deraco

Download or read book Cytoreductive Surgery and Perioperative Chemotherapy for Peritoneal Surface Malignancy written by Marcello Deraco and published by Cine Med, Incorporated. This book was released on 2012-10-01 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prior to the use of the combined treatment of cytoreductive surgery (CRS) and perioperative chemotherapy (POC), peritoneal metastases were uniformly fatal. While the combined treatment of CRS and POC has been practiced for nearly 30 years, the benefits of the treatment are just emerging. This text is for surgical and medical oncologists, and describes the rationale, treatment, and results of treatment of peritoneal metastases, peritoneal mesothelioma, and sarcomatosis. Internationally renowned peritoneal surface oncology teams have authored the chapters. The text is accompanied by surgical video presentations which includes on-camera commentary by the international experts offering his or her own approach to CRS and POC.

Perioperative Care of the Cancer Patient

Author : Carin A. Hagberg
Publisher : Elsevier Health Sciences
ISBN 13 : 032369585X
Total Pages : 659 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Perioperative Care of the Cancer Patient by : Carin A. Hagberg

Download or read book Perioperative Care of the Cancer Patient written by Carin A. Hagberg and published by Elsevier Health Sciences. This book was released on 2022-03-26 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 80% of patients with cancer will need the services of anesthesiology and perioperative medicine, intensive care medicine, and pain management specialists during their cancer journey for diagnostic, therapeutic, and symptom management needs, as well as for the management of recurrent disease, secondary cancers, and ongoing non-oncologic surgical needs during survivorship. Perioperative Care of the Cancer Patient is today’s most up-to-date, authoritative, comprehensive reference on the acute care of surgical patients with cancer, from a team of international experts in this emerging and dynamic specialty. Covers current clinical practice and perioperative care guidelines during the entire cancer journey for both adult and pediatric patients. Includes a diverse array of topics on cancer care, such as cancer epidemiology, cancer biology, ethics in cancer care delivery, value proposition in cancer care, opportunities and challenges with research programs in perioperative cancer care, application of big data and computational sciences in cancer medicine and care delivery, and the MD Anderson Cancer Center Moon Shots Program®. Discusses newer cancer therapies and their perioperative implications, functional assessment and prehabilitation, enhanced recovery programs in cancer care, challenges with novel cancer therapies in the care of the critically ill cancer patient, chronic and interventional pain management in patients with cancer, and more. An educational resource and clinical reference for surgeons, anesthesia practitioners, hospitalists, internists, pain physicians, intensivists, basic science researchers, and all clinicians involved in the acute care of surgical patients with cancer.

The Chemotherapy Source Book

Author : Michael Clinton Perry
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781773287
Total Pages : 820 pages
Book Rating : 4.7/5 (732 download)

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Book Synopsis The Chemotherapy Source Book by : Michael Clinton Perry

Download or read book The Chemotherapy Source Book written by Michael Clinton Perry and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemotherapy Source Book, Fourth Edition pulls together all the current information on the chemotherapeutic management of cancer patients, including choice of chemotherapeutic agents, use of combinations, and toxicity of individual drugs. Organized by disease site, the book brings together pharmacologic and patient management information in one source that clinicians can consult for any question encountered in the delivery of chemotherapy. This updated Fourth Edition includes new drugs as well as new indications for older drugs. Content has been streamlined to provide essential information more quickly for the busy practitioner. Plus, this edition is softcover for greater portability and convenience.

Peritoneal Surface Malignancies

Author : Emel Canbay
Publisher : Springer
ISBN 13 : 3319129376
Total Pages : 109 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Peritoneal Surface Malignancies by : Emel Canbay

Download or read book Peritoneal Surface Malignancies written by Emel Canbay and published by Springer. This book was released on 2015-07-09 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by our leader Paul H. Sugarbaker are performed to treat peritoneal metastases by surgeons all around the world. Therefore this book is focused on detailed surgical anatomy of the peritoneum, preoperative clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipments, different surgical procedures for CRS and reconstruction, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies. The chapter on molecular mechanisms of the formation of peritoneal carcinomatosis provides insight into a rapidly expanding knowledge within this speciality. This book should be valuable for surgical oncologists who deal with multimodal treatment for peritoneal surface malignancies, as well as for the trained peritonectomy surgeons. For the senior surgeons, it will also introduce new techniques and approaches in this field such as dealing with the omental cakes and massive organ involvement that requires multi-organ resection.

Original Article: Role of Adjuvant Chemotherapy in a Perioperative Chemotherapy Regimen for Gastric Cancer

Author : Baicheng Baicheng Press
Publisher :
ISBN 13 : 9781540678409
Total Pages : 40 pages
Book Rating : 4.6/5 (784 download)

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Book Synopsis Original Article: Role of Adjuvant Chemotherapy in a Perioperative Chemotherapy Regimen for Gastric Cancer by : Baicheng Baicheng Press

Download or read book Original Article: Role of Adjuvant Chemotherapy in a Perioperative Chemotherapy Regimen for Gastric Cancer written by Baicheng Baicheng Press and published by . This book was released on 2016-11-27 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multimodal treatment strategies - perioperative chemotherapy (CTx) and radical surgery - are currently accepted as treatment standard for locally advanced gastric cancer. However, the role of adjuvant postoperative CTx (postCTx) in addition to neoadjuvant preoperative CTx (preCTx) in this setting remains controversial. Proceeds from the sale of this book go to support an elderly disabled person.

Surgery for Ovarian Cancer

Author : Robert E. Bristow
Publisher : CRC Press
ISBN 13 : 0429578857
Total Pages : 437 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Surgery for Ovarian Cancer by : Robert E. Bristow

Download or read book Surgery for Ovarian Cancer written by Robert E. Bristow and published by CRC Press. This book was released on 2019-02-21 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The chapters cover relevant anatomical considerations, surgical challenges specific to each region, and operative approaches and techniques favored by the authors. The list of contributing authors has been expanded from the previous edition and includes international and world-renowned experts from the fields of gynecologic oncology and surgical oncology. The topics of minimally invasive surgery, secondary cytoreduction, palliative surgery, and postoperative care are also covered in detail. New to the third edition are chapters on preoperative risk stratification, regional therapeutics and peritonectomy procedures, and quality assurance relating to ovarian cancer surgery. This comprehensive text is essential reading for all practitioners working with patients with ovarian cancers.

Perioperative Inflammation as Triggering Origin of Metastasis Development

Author : Michael W. Retsky
Publisher : Springer
ISBN 13 : 3319579436
Total Pages : 236 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Perioperative Inflammation as Triggering Origin of Metastasis Development by : Michael W. Retsky

Download or read book Perioperative Inflammation as Triggering Origin of Metastasis Development written by Michael W. Retsky and published by Springer. This book was released on 2017-06-28 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses. With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.

Anesthesia and Perioperative Care of the High-Risk Patient

Author : Ian McConachie
Publisher : Cambridge University Press
ISBN 13 : 1107690579
Total Pages : 501 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Anesthesia and Perioperative Care of the High-Risk Patient by : Ian McConachie

Download or read book Anesthesia and Perioperative Care of the High-Risk Patient written by Ian McConachie and published by Cambridge University Press. This book was released on 2014-09-04 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise summary of perioperative management of high-risk surgical patients, bridging the gap between the operating theatre and ICU.

Recent Advances in Cancer Research and Therapy

Author : Xin-Yuan Liu
Publisher : Elsevier
ISBN 13 : 012397836X
Total Pages : 700 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Recent Advances in Cancer Research and Therapy by : Xin-Yuan Liu

Download or read book Recent Advances in Cancer Research and Therapy written by Xin-Yuan Liu and published by Elsevier. This book was released on 2012-05-18 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.

Multidisciplinary Treatment of Hepatocellular Carcinoma

Author : Jean-Nicolas` Vauthey
Publisher : Springer Science & Business Media
ISBN 13 : 3642160379
Total Pages : 266 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Multidisciplinary Treatment of Hepatocellular Carcinoma by : Jean-Nicolas` Vauthey

Download or read book Multidisciplinary Treatment of Hepatocellular Carcinoma written by Jean-Nicolas` Vauthey and published by Springer Science & Business Media. This book was released on 2012-08-31 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now widely accepted that multidisciplinary collaboration and multimodality treatment approaches are important in improving the survival of patients with hepatocellular carcinoma. In this comprehensive textbook, internationally renowned experts in the field present and discuss the various strategies employed in the treatment of the disease. Up-to-date information is provided on the indications for and outcome of a range of treatment options, including surgical resection, liver transplantation, radiofrequency ablation, transarterial chemoembolization, yttrium-90 transarterial radioembolization, and systemic therapy. In addition, important background information is included on biology, pathology, staging, and imaging. This book will be particularly helpful to all professionals and trainees worldwide who have an interest in the diagnosis and treatment of hepatocellular carcinoma.

Peritoneal Carcinomatosis: Principles of Management

Author : Paul H. Sugarbaker
Publisher : Springer Science & Business Media
ISBN 13 : 1461312477
Total Pages : 434 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Peritoneal Carcinomatosis: Principles of Management by : Paul H. Sugarbaker

Download or read book Peritoneal Carcinomatosis: Principles of Management written by Paul H. Sugarbaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.

Surgical Challenges of the Foregut An Issue of Surgical Clinics

Author : Sushanth Reddy
Publisher : Elsevier Health Sciences
ISBN 13 : 0323678068
Total Pages : pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Surgical Challenges of the Foregut An Issue of Surgical Clinics by : Sushanth Reddy

Download or read book Surgical Challenges of the Foregut An Issue of Surgical Clinics written by Sushanth Reddy and published by Elsevier Health Sciences. This book was released on 2019-05-08 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Clinics of North America focuses on Surgical Challenges of Foregut Malignancies and is edited by Dr. Sushanth Reddy. Articles will include: Molecular basis of gastric and esophageal tumors; Multidisciplinary therapy of gastric cancers; Management of early stage gastric and esophageal disease; What is the best operation for proximal gastric cancer and distal esophageal cancer?; The difficult esophageal conduit; Managing the Western patient in contrast to the Eastern patient; Complications after esophagectomy; Next generation sequencing in the management of gastric and esophageal cancers; Managing squamous cell esophageal cancer; Esophageal and gastric GISTs; Surgical Challenges of Foregut Malignancies; and more!

Perioperative antineoplastische Chemotherapie

Author : P. Preusser
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Perioperative antineoplastische Chemotherapie by : P. Preusser

Download or read book Perioperative antineoplastische Chemotherapie written by P. Preusser and published by . This book was released on 1988 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surgical Management of Advanced Pelvic Cancer

Author : Desmond C. Winter
Publisher : John Wiley & Sons
ISBN 13 : 1119518407
Total Pages : 324 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Surgical Management of Advanced Pelvic Cancer by : Desmond C. Winter

Download or read book Surgical Management of Advanced Pelvic Cancer written by Desmond C. Winter and published by John Wiley & Sons. This book was released on 2021-11-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.