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Author : Indira Gajula
Publisher :
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.:/5 (329 download)
Download or read book Lipids Metabolism in Ischemic Heart Mitochondrial Inner Membrane written by Indira Gajula and published by . This book was released on 1994 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shijun Wang
Publisher : Frontiers Media SA
ISBN 13 : 2889766209
Total Pages : 245 pages
Book Rating : 4.8/5 (897 download)
Download or read book Mitochondrial Metabolism in Ischemic Heart Disease written by Shijun Wang and published by Frontiers Media SA. This book was released on 2022-07-27 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ger J. van der Vusse
Publisher : Springer Science & Business Media
ISBN 13 : 1461316111
Total Pages : 210 pages
Book Rating : 4.4/5 (613 download)
Download or read book Lipid Metabolism in Normoxic and Ischemic Heart written by Ger J. van der Vusse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: During recent decades, bewildering progress has occurred in the field of Molecular and Cellular Biochemistry. Progress has been extraordinarily rapid primarily because of the challenge for finding solutions to a wide variety of diseases and the availability of new techniques for monitoring biochemical processes. This has resulted in a voluminous and complex literature in the field of biochemical medicine so that there is a clear need for the synthesis and analysis of the continuing expansion of valuable data. It was thus considered appropriate to initiate a new series of monographs, each dedicated to a specialized area of investigation, encompassing molecular and cellular processes in health and disease. Most of the biochemical scientists have devoted their energies in understanding the fundamentals of biochemistry and indeed impressive advances have been made in the past. However, the full potential for explanation has been hampered by the concept of universality of biochemical reactions occurring in the cell. In view of the fact that each organ in the body performs a distinct function, it is now beginning to be realized that each cell type is unique in its need to survive and perform its specific function. Accordingly, the aspect of individualty is receiving increased attention for revealing new avenues in the study of pathophysiology of cellular abnormalities.
Author : R. Ferrari
Publisher : Springer
ISBN 13 :
Total Pages : 362 pages
Book Rating : 4.3/5 (91 download)
Download or read book Myocardial Ischemia and Lipid Metabolism written by R. Ferrari and published by Springer. This book was released on 1984 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past years, the thrust of research in cardiology has been toward an understanding of the engineering of the heart as a pump that transports blood to the various organs of the body. More recently, the fields of biochemistry and biophysics have come to influence heart research. The modern cardiologist can no longer pretend to understand, for example, what is happening to the patient with myocardial infarction or ischemia without understanding the principles of molecular biology. The structure and function of the heart are therefore central themes of cardiological research and practice, which incorporate knowledge and discoveries from diverse disciplines. The importance of lipid metabolism in the myocardium has become clearly understood. In the well-oxygenated heart, fatty acids are the preferred substrates. The fact that the heart derives most of its energy from the oxidation of lipids, which represent the larg est energy store of the body, is logical for an organ that must work throughout our lifetime. There are, however, several lines of evidence that during ischemia, lipids may. be harmful to the heart. High levels of free fatty acids in the serum have been suggested to play a role in causing life-threatening arryhthmias and damage in the ischemic heart. The molecular basis for these effects remains poorly understood, and several possible mechanisms for these harm ful effects have been suggested.
Author : Ger J. van der Vusse
Publisher : Springer Science & Business Media
ISBN 13 : 146153514X
Total Pages : 197 pages
Book Rating : 4.4/5 (615 download)
Download or read book Lipid Metabolism in the Healthy and Disease Heart written by Ger J. van der Vusse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Third International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart, September 9 & 10, 1991, Rotterdam, The Netherlands
Author : H. Stam
Publisher : Springer Science & Business Media
ISBN 13 : 3662083906
Total Pages : 454 pages
Book Rating : 4.6/5 (62 download)
Download or read book Lipid metabolism in the normoxic and ischaemic heart written by H. Stam and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific progress with respect to the important role of various lipids in myocardial function and the dearrangements of lipid metabolism underlying ischaemic heart disease(s) has been con siderable in recent years. In 1986 alone, an overall number ofl 044 full papers covering the topics "Lipids-Heart-Heart Disease", have been published in a variety of biochemistry, physiology, pharmacology and cardiology journals (source: Index Medicus). They have broadened our in sight into the molecular basis of myocardial lipidology and the lipido-chemical basis of car diology in health and disease, and have narrowed the gap between promising pharmacological intervention in experimental animals and clinical treatment of patients suffering from an ischaemic heart. Furthermore, they illustrate the fundamental significance of the product of the union between basic and clinical science. The rapid development of knowledge in the "Lipids-Heart-Heart Disease" triad prompted us to organize the International Symposium on Lipid Metabolism in the Normoxic and lschaemic Heart, held in Rotterdam (The Netherlands) on September 22 and 23, 1986. This meeting was a coproject of the Department of Biochemistry I (Medical Faculty, Erasmus University Rotter dam) and the Department of Physiology (Medical Faculty, University of Limburg) and was held under the auspices of the GerritJan Mulder Foundation (named after a famous Rotterdam physi cian and chemist who lived from 1802-1880) whom we thank for their co-operation. The present volume is a compendium of invited papers and contributions selected from the posters presented during the symposium.
Author : Rong Shao
Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (312 download)
Download or read book Study of Mitochondrial Inner Membrane Subpopulations of the Rat Heart Under Induced Ischemia written by Rong Shao and published by . This book was released on 1993 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : H. Stam
Publisher : Springer Verlag
ISBN 13 : 9780387912912
Total Pages : 269 pages
Book Rating : 4.9/5 (129 download)
Download or read book Lipid Metabolism in the Normoxic and Ischaemic Heart written by H. Stam and published by Springer Verlag. This book was released on 1987 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Pierce A. Grace
Publisher : Wiley-Blackwell
ISBN 13 : 9780632050215
Total Pages : 400 pages
Book Rating : 4.0/5 (52 download)
Download or read book Ischaemia-Reperfusion Injury written by Pierce A. Grace and published by Wiley-Blackwell. This book was released on 1999-02-04 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ischaemia-Reperfusion Injury is concerned with the consequences of interrupting and restoring blood flow to tissues. Many common clinical conditions are caused by interruption of blood flow to tissues (eg, ischaemic heart disease, peripheral vascular disease, stroke); blood flow is also interrupted deliberately in many surgical procedures (eg, cardiac surgery, arterial surgery, transplant surgery, limb surgery with tourniquet). In treating such conditions or after performing such operations the aim of the clinician is to restore the blood supply to the ischaemic tissue. Paradoxically, restoration of blood flow to ischaemic tissues can lead to further tissue damage with the potential for severe local and systemic injury. This book focuses on the clinical, pathological and biochemical processes involved in ischaemia-reperfusion injury and gives an overview of the strategies that may be adopted to mitigate or prevent such injury. This book will be of interest to both clinicians and scientists who have to deal with or have interest in this difficult but important problem.
Author : José Marín-García
Publisher : Springer Science & Business Media
ISBN 13 : 0387255745
Total Pages : 415 pages
Book Rating : 4.3/5 (872 download)
Download or read book Mitochondria and the Heart written by José Marín-García and published by Springer Science & Business Media. This book was released on 2005-05-05 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex network of cellular interactions, involving (1) generation and detoxification of reactive oxygen species, including superoxide anion, hy-drogen peroxide, and hydroxyl radical; (2) maintenance of the antioxidant glutathione in a reduced state and adequate level of mitochondrial matrix superoxide dismutase; (3) cytoplasmic calcium homeostasis, particularly under conditions of cellular calcium loading; (4) transport of metabolites between cytoplasm and matrix; (5) both programmed (apoptosis) and necrotic cell death; and (6) cell growth and development. It is therefore not surprising that this organelle has come to be the center stage in many current investigations of cardiovascular diseases, aging, and agi- related disease. Concomitant with these advances, an impressive effort is under- way for the development of new tools and methodologies to study mitochondrial structure and function, including powerful ways to visualize, monitor, and alter the organelle function to assess the genetic consequences of these perturbations.
Author : Lawrence H. Lash
Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)
Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author : R. Ferrari
Publisher : Springer Science & Business Media
ISBN 13 : 146844865X
Total Pages : 337 pages
Book Rating : 4.4/5 (684 download)
Download or read book Myocardial Ischemia and Lipid Metabolism written by R. Ferrari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past years, the thrust of research in cardiology has been toward an understanding of the engineering of the heart as a pump that transports blood to the various organs of the body. More recently, the fields of biochemistry and biophysics have come to influence heart research. The modern cardiologist can no longer pretend to understand, for example, what is happening to the patient with myocardial infarction or ischemia without understanding the principles of molecular biology. The structure and function of the heart are therefore central themes of cardiological research and practice, which incorporate knowledge and discoveries from diverse disciplines. The importance of lipid metabolism in the myocardium has become clearly understood. In the well-oxygenated heart, fatty acids are the preferred substrates. The fact that the heart derives most of its energy from the oxidation of lipids, which represent the larg est energy store of the body, is logical for an organ that must work throughout our lifetime. There are, however, several lines of evidence that during ischemia, lipids may. be harmful to the heart. High levels of free fatty acids in the serum have been suggested to play a role in causing life-threatening arryhthmias and damage in the ischemic heart. The molecular basis for these effects remains poorly understood, and several possible mechanisms for these harm ful effects have been suggested.
Author : Lionel H. Opie
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 672 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Heart written by Lionel H. Opie and published by Lippincott Williams & Wilkins. This book was released on 1998 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical cardiac physiology for residents and practitioners. Halftone and color illustrations and tables.
Author : Andrew L. Clark
Publisher : Oxford University Press
ISBN 13 : 019876622X
Total Pages : 897 pages
Book Rating : 4.1/5 (987 download)
Download or read book Oxford Textbook of Heart Failure written by Andrew L. Clark and published by Oxford University Press. This book was released on 2022 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking the reader from an understanding of the basic mechanisms of heart failure through to an appreciation of the complexities of heart failure management and the remarkable improvements possible with good treatment, the Oxford Textbook of Heart Failure 2e covers all aspects necessary to manage a patient with heart failure. In full colour throughout, containing over 300 illustrations, and supported by detailed referencing from the huge evidence base that has developed over the last two decades, the textbook also includes extensive chapters on common co-morbidities. The new edition has been completely updated in line with new British and European Guidelines and contains new chapters on; Natriuretic Peptides and Novel Biomarkers in Heart Failure, The Future of Heart Failure, and Regenerative Therapies. Essential reading for consultant cardiologists and those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, pharmacists, and specialist nurses.
Author : J.W. de Jong
Publisher : Springer
ISBN 13 : 9789401041225
Total Pages : 400 pages
Book Rating : 4.0/5 (412 download)
Download or read book The Carnitine System written by J.W. de Jong and published by Springer. This book was released on 2012-01-11 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years, derivatives of L-carnitine, such as acetyl-L-carnitine and propionyl-L-carnitine, have been made available to doctors for treatment of specific pathologies. The effects of this family of related carnitine compounds on cardiovascular systems and diseases constitute the major issue addressed in this volume. Although several books on carnitine have been published, a treatise focusing on experimental and clinical aspects of the carnitine family and cardiovascular diseases was lacking. The present book provides the reader with a concise update in this field. The information collected from experts on various aspects of the fascinating compound, carnitine, will be useful for both clinicians and basic scientists.
Author : Alexandre Mebazaa
Publisher : Springer Science & Business Media
ISBN 13 : 1846287820
Total Pages : 922 pages
Book Rating : 4.8/5 (462 download)
Download or read book Acute Heart Failure written by Alexandre Mebazaa and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
Author : J K Parker
Publisher : Elsevier
ISBN 13 : 1782421114
Total Pages : 448 pages
Book Rating : 4.7/5 (824 download)
Download or read book Flavour Development, Analysis and Perception in Food and Beverages written by J K Parker and published by Elsevier. This book was released on 2014-11-19 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flavour is a critical aspect of food production and processing, requiring careful design, monitoring and testing in order to create an appealing food product. This book looks at flavour generation, flavour analysis and sensory perception of food flavour and how these techniques can be used in the food industry to create new and improve existing products. Part one covers established and emerging methods of characterising and analysing taste and aroma compounds. Part two looks at different factors in the generation of aroma. Finally, part three focuses on sensory analysis of food flavour. Covers the analysis and characterisation of aromas and taste compounds Examines how aromas can be created and predicted Reviews how different flavours are perceived
