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Lipid Metabolism In The Normoxic And Ischemic Heart
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Book Synopsis Lipid Metabolism in Normoxic and Ischemic Heart by : Ger J. van der Vusse
Download or read book Lipid Metabolism in Normoxic and Ischemic Heart written by Ger J. van der Vusse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: During recent decades, bewildering progress has occurred in the field of Molecular and Cellular Biochemistry. Progress has been extraordinarily rapid primarily because of the challenge for finding solutions to a wide variety of diseases and the availability of new techniques for monitoring biochemical processes. This has resulted in a voluminous and complex literature in the field of biochemical medicine so that there is a clear need for the synthesis and analysis of the continuing expansion of valuable data. It was thus considered appropriate to initiate a new series of monographs, each dedicated to a specialized area of investigation, encompassing molecular and cellular processes in health and disease. Most of the biochemical scientists have devoted their energies in understanding the fundamentals of biochemistry and indeed impressive advances have been made in the past. However, the full potential for explanation has been hampered by the concept of universality of biochemical reactions occurring in the cell. In view of the fact that each organ in the body performs a distinct function, it is now beginning to be realized that each cell type is unique in its need to survive and perform its specific function. Accordingly, the aspect of individualty is receiving increased attention for revealing new avenues in the study of pathophysiology of cellular abnormalities.
Book Synopsis Lipid metabolism in the normoxic and ischaemic heart by : H. Stam
Download or read book Lipid metabolism in the normoxic and ischaemic heart written by H. Stam and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific progress with respect to the important role of various lipids in myocardial function and the dearrangements of lipid metabolism underlying ischaemic heart disease(s) has been con siderable in recent years. In 1986 alone, an overall number ofl 044 full papers covering the topics "Lipids-Heart-Heart Disease", have been published in a variety of biochemistry, physiology, pharmacology and cardiology journals (source: Index Medicus). They have broadened our in sight into the molecular basis of myocardial lipidology and the lipido-chemical basis of car diology in health and disease, and have narrowed the gap between promising pharmacological intervention in experimental animals and clinical treatment of patients suffering from an ischaemic heart. Furthermore, they illustrate the fundamental significance of the product of the union between basic and clinical science. The rapid development of knowledge in the "Lipids-Heart-Heart Disease" triad prompted us to organize the International Symposium on Lipid Metabolism in the Normoxic and lschaemic Heart, held in Rotterdam (The Netherlands) on September 22 and 23, 1986. This meeting was a coproject of the Department of Biochemistry I (Medical Faculty, Erasmus University Rotter dam) and the Department of Physiology (Medical Faculty, University of Limburg) and was held under the auspices of the GerritJan Mulder Foundation (named after a famous Rotterdam physi cian and chemist who lived from 1802-1880) whom we thank for their co-operation. The present volume is a compendium of invited papers and contributions selected from the posters presented during the symposium.
Book Synopsis Lipid Metabolism in the Healthy and Disease Heart by : Ger J. van der Vusse
Download or read book Lipid Metabolism in the Healthy and Disease Heart written by Ger J. van der Vusse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Third International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart, September 9 & 10, 1991, Rotterdam, The Netherlands
Book Synopsis Lipid Metabolism in the Normoxic and Ischaemic Heart by : H. Stam
Download or read book Lipid Metabolism in the Normoxic and Ischaemic Heart written by H. Stam and published by Springer Verlag. This book was released on 1987 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Metabolism in Normoxic and Ischemic Heart by : Ger J Van Der Vusse
Download or read book Lipid Metabolism in Normoxic and Ischemic Heart written by Ger J Van Der Vusse and published by . This book was released on 1989-11-30 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Myocardial Ischemia and Lipid Metabolism by : R. Ferrari
Download or read book Myocardial Ischemia and Lipid Metabolism written by R. Ferrari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past years, the thrust of research in cardiology has been toward an understanding of the engineering of the heart as a pump that transports blood to the various organs of the body. More recently, the fields of biochemistry and biophysics have come to influence heart research. The modern cardiologist can no longer pretend to understand, for example, what is happening to the patient with myocardial infarction or ischemia without understanding the principles of molecular biology. The structure and function of the heart are therefore central themes of cardiological research and practice, which incorporate knowledge and discoveries from diverse disciplines. The importance of lipid metabolism in the myocardium has become clearly understood. In the well-oxygenated heart, fatty acids are the preferred substrates. The fact that the heart derives most of its energy from the oxidation of lipids, which represent the larg est energy store of the body, is logical for an organ that must work throughout our lifetime. There are, however, several lines of evidence that during ischemia, lipids may. be harmful to the heart. High levels of free fatty acids in the serum have been suggested to play a role in causing life-threatening arryhthmias and damage in the ischemic heart. The molecular basis for these effects remains poorly understood, and several possible mechanisms for these harm ful effects have been suggested.
Book Synopsis Lipid Metabolism in the Normoxic and Ischemic Heart by : Nederlandse Hartstichting
Download or read book Lipid Metabolism in the Normoxic and Ischemic Heart written by Nederlandse Hartstichting and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis 2nd International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart by : University of Limburg
Download or read book 2nd International Symposium on Lipid Metabolism in the Normoxic and Ischemic Heart written by University of Limburg and published by . This book was released on 1988 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Metabolism in the Healthy and Diseased Heart by : Ger J. van der Vusse
Download or read book Lipid Metabolism in the Healthy and Diseased Heart written by Ger J. van der Vusse and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Metabolism and Health by : Robert J. Moffatt
Download or read book Lipid Metabolism and Health written by Robert J. Moffatt and published by CRC Press. This book was released on 2005-12-15 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: That a relation exists between lipids/lipoproteins and coronary artery disease is no longer an arguable point. However, the complexities associated with this relationship, and the number of factors that can impact and alter circumstances and clinical status, are many and diverse. Consequently, this relationship continues to receive a great deal of
Book Synopsis Drugs Affecting Lipid Metabolism by : Alberico L. Catapano
Download or read book Drugs Affecting Lipid Metabolism written by Alberico L. Catapano and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of experimental, clinical and epidemiological data have been gathered to confirm the strict and causal correlation between plasma lipoproteins and coronary heart disease. However, as usually happens in research, many more interesting issues are being studied, opening new fields of research for the future. These new advances, together with the combined efforts of cell biologists and lipoprotein chemists, have set the pace for an exciting period of research and clinical applications of diets and drugs affecting plasma and cell lipids. This volume, which includes the work of many of the leading world labortories, represents an authoritative and up-to-date appraisal of the status of the art and a stimulus to future research at the laboratory and clinical level in a fascinating area of clinical and preventive medicine.
Book Synopsis Drugs Affecting Lipid Metabolism by : Antonio M. Gotto
Download or read book Drugs Affecting Lipid Metabolism written by Antonio M. Gotto and published by Springer. This book was released on 1996-08-31 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even a brief scan of the table of contents of the present volume is enough to disclose the diversity of research interests and opinions in the field of lipidology. It is precisely this diversity that is the strength of our field and that was showcased by the XII International Symposium of DRUGS AFFECTING LIPID METABOLISM (DALM). The papers published here from these proceedings may be divided into three categories: those that define-and refine---our understanding ofthe clinical benefit of aggressive lipid management, those that develop our knowledge of ris!. assessment, and those that discuss the genetic, bio~hemical, and biophysical mechanisms underlying the pathology of coronary heart disease. On the clinical front, further analysis of the results of the Scandinavian Simvastatin Survival Study (4S) has indicated the cost-effectiveness of therapy in patients with established coronary heart disease. The West of Scotland Coronary Prevention Study (WOSCOPS), whose methodology was described at the DALM XII symposium, has demonstrated in a mostly primary-prevention population what 4S demonstrated for secondary prevention the year before: aggressive lipid-regulating therapy reduces coronary heart disease morbidity and mortality rates without concurrently increasing mortality from noncardiovascular causes. In the future, important considerations will be to develop protocols that maximize benefit in groups underrepresented in traditional clinical research for example, women and the elderly-and to improve compliance to existing treatment regimens. Furthermore, antioxidant, omega-3 fatty acid, and gene therapies warrant further investigation.
Book Synopsis Lipid Metabolism in Normoxic and Ischemic Hearth by :
Download or read book Lipid Metabolism in Normoxic and Ischemic Hearth written by and published by . This book was released on 1989 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Manual of Lipid Disorders by : Antonio M. Gotto
Download or read book Manual of Lipid Disorders written by Antonio M. Gotto and published by . This book was released on 2003 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The newly revised Third Edition of this practical manual offers up-to-date clinical guidelines for evaluating and treating lipid disorders and reducing the risk for coronary heart disease. The book reviews recent advances in the understanding of lipid metabolism and atherogenesis, examines clinical trial results with lipid-regulating drugs, and discusses appropriate dietary and lifestyle modifications. This edition includes the 2001 National Cholesterol Education Program clinical guidelines for assessment and management of lipid disorders in adults. Close attention is given to plasma lipid control and coronary heart disease risk reduction in patients with diabetes mellitus, overweight/obese individuals, women, elderly patients, and younger patients.
Book Synopsis Lipids Metabolism in Ischemic Heart Mitochondrial Inner Membrane by : Indira Gajula
Download or read book Lipids Metabolism in Ischemic Heart Mitochondrial Inner Membrane written by Indira Gajula and published by . This book was released on 1994 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cardiac Metabolism in Health and Disease by : Salah Abdel-aleem
Download or read book Cardiac Metabolism in Health and Disease written by Salah Abdel-aleem and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and pathological conditions, and several other important topics in this area of research. We hope that this special issue of Molecular and Cellular Biochemistry provides an up-to-date source of information for scientists and clinicians interested in the mechanism by which cardiac metabolism is regulated in health and disease and the mechanistic relationship between disturbances in cardiac metabolism and the genesis of cardiovascular diseases.
Book Synopsis Cardiac Energy Metabolism in Health and Disease by : Gary D. Lopaschuk
Download or read book Cardiac Energy Metabolism in Health and Disease written by Gary D. Lopaschuk and published by Springer. This book was released on 2014-08-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.