Large-Scale Inverse Problems and Quantification of Uncertainty

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Publisher : Wiley
ISBN 13 : 9780470685853
Total Pages : 0 pages
Book Rating : 4.6/5 (858 download)

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Book Synopsis Large-Scale Inverse Problems and Quantification of Uncertainty by : Lorenz Biegler

Download or read book Large-Scale Inverse Problems and Quantification of Uncertainty written by Lorenz Biegler and published by Wiley. This book was released on 2010-10-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on computational methods for large-scale statistical inverse problems and provides an introduction to statistical Bayesian and frequentist methodologies. Recent research advances for approximation methods are discussed, along with Kalman filtering methods and optimization-based approaches to solving inverse problems. The aim is to cross-fertilize the perspectives of researchers in the areas of data assimilation, statistics, large-scale optimization, applied and computational mathematics, high performance computing, and cutting-edge applications. The solution to large-scale inverse problems critically depends on methods to reduce computational cost. Recent research approaches tackle this challenge in a variety of different ways. Many of the computational frameworks highlighted in this book build upon state-of-the-art methods for simulation of the forward problem, such as, fast Partial Differential Equation (PDE) solvers, reduced-order models and emulators of the forward problem, stochastic spectral approximations, and ensemble-based approximations, as well as exploiting the machinery for large-scale deterministic optimization through adjoint and other sensitivity analysis methods. Key Features: • Brings together the perspectives of researchers in areas of inverse problems and data assimilation. • Assesses the current state-of-the-art and identify needs and opportunities for future research. • Focuses on the computational methods used to analyze and simulate inverse problems. • Written by leading experts of inverse problems and uncertainty quantification. Graduate students and researchers working in statistics, mathematics and engineering will benefit from this book.

Large-Scale Inverse Problems and Quantification of Uncertainty

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Publisher : John Wiley & Sons
ISBN 13 : 1119957583
Total Pages : 403 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Large-Scale Inverse Problems and Quantification of Uncertainty by : Lorenz Biegler

Download or read book Large-Scale Inverse Problems and Quantification of Uncertainty written by Lorenz Biegler and published by John Wiley & Sons. This book was released on 2011-06-24 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on computational methods for large-scale statistical inverse problems and provides an introduction to statistical Bayesian and frequentist methodologies. Recent research advances for approximation methods are discussed, along with Kalman filtering methods and optimization-based approaches to solving inverse problems. The aim is to cross-fertilize the perspectives of researchers in the areas of data assimilation, statistics, large-scale optimization, applied and computational mathematics, high performance computing, and cutting-edge applications. The solution to large-scale inverse problems critically depends on methods to reduce computational cost. Recent research approaches tackle this challenge in a variety of different ways. Many of the computational frameworks highlighted in this book build upon state-of-the-art methods for simulation of the forward problem, such as, fast Partial Differential Equation (PDE) solvers, reduced-order models and emulators of the forward problem, stochastic spectral approximations, and ensemble-based approximations, as well as exploiting the machinery for large-scale deterministic optimization through adjoint and other sensitivity analysis methods. Key Features: Brings together the perspectives of researchers in areas of inverse problems and data assimilation. Assesses the current state-of-the-art and identify needs and opportunities for future research. Focuses on the computational methods used to analyze and simulate inverse problems. Written by leading experts of inverse problems and uncertainty quantification. Graduate students and researchers working in statistics, mathematics and engineering will benefit from this book.

Bayesian Uncertainty Quantification for Large Scale Spatial Inverse Problems

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (817 download)

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Book Synopsis Bayesian Uncertainty Quantification for Large Scale Spatial Inverse Problems by : Anirban Mondal

Download or read book Bayesian Uncertainty Quantification for Large Scale Spatial Inverse Problems written by Anirban Mondal and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: We considered a Bayesian approach to nonlinear inverse problems in which the unknown quantity is a high dimension spatial field. The Bayesian approach contains a natural mechanism for regularization in the form of prior information, can incorporate information from heterogeneous sources and provides a quantitative assessment of uncertainty in the inverse solution. The Bayesian setting casts the inverse solution as a posterior probability distribution over the model parameters. Karhunen-Lo'eve expansion and Discrete Cosine transform were used for dimension reduction of the random spatial field. Furthermore, we used a hierarchical Bayes model to inject multiscale data in the modeling framework. In this Bayesian framework, we have shown that this inverse problem is well-posed by proving that the posterior measure is Lipschitz continuous with respect to the data in total variation norm. The need for multiple evaluations of the forward model on a high dimension spatial field (e.g. in the context of MCMC) together with the high dimensionality of the posterior, results in many computation challenges. We developed two-stage reversible jump MCMC method which has the ability to screen the bad proposals in the first inexpensive stage. Channelized spatial fields were represented by facies boundaries and variogram-based spatial fields within each facies. Using level-set based approach, the shape of the channel boundaries was updated with dynamic data using a Bayesian hierarchical model where the number of points representing the channel boundaries is assumed to be unknown. Statistical emulators on a large scale spatial field were introduced to avoid the expensive likelihood calculation, which contains the forward simulator, at each iteration of the MCMC step. To build the emulator, the original spatial field was represented by a low dimensional parameterization using Discrete Cosine Transform (DCT), then the Bayesian approach to multivariate adaptive regression spline (BMARS) was used to emulate the simulator. Various numerical results were presented by analyzing simulated as well as real data.

Computational Uncertainty Quantification for Inverse Problems

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Publisher : SIAM
ISBN 13 : 1611975387
Total Pages : 141 pages
Book Rating : 4.6/5 (119 download)

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Book Synopsis Computational Uncertainty Quantification for Inverse Problems by : Johnathan M. Bardsley

Download or read book Computational Uncertainty Quantification for Inverse Problems written by Johnathan M. Bardsley and published by SIAM. This book was released on 2018-08-01 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to both computational inverse problems and uncertainty quantification (UQ) for inverse problems. The book also presents more advanced material on Bayesian methods and UQ, including Markov chain Monte Carlo sampling methods for UQ in inverse problems. Each chapter contains MATLAB? code that implements the algorithms and generates the figures, as well as a large number of exercises accessible to both graduate students and researchers. Computational Uncertainty Quantification for Inverse Problems is intended for graduate students, researchers, and applied scientists. It is appropriate for courses on computational inverse problems, Bayesian methods for inverse problems, and UQ methods for inverse problems.

Large Scale Inverse Problems

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Publisher : Walter de Gruyter
ISBN 13 : 3110282267
Total Pages : 216 pages
Book Rating : 4.1/5 (12 download)

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Book Synopsis Large Scale Inverse Problems by : Mike Cullen

Download or read book Large Scale Inverse Problems written by Mike Cullen and published by Walter de Gruyter. This book was released on 2013-08-29 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is thesecond volume of a three volume series recording the "Radon Special Semester 2011 on Multiscale Simulation & Analysis in Energy and the Environment" that took placein Linz, Austria, October 3-7, 2011. This volume addresses the common ground in the mathematical and computational procedures required for large-scale inverse problems and data assimilation in forefront applications. The solution of inverse problems is fundamental to a wide variety of applications such as weather forecasting, medical tomography, and oil exploration. Regularisation techniques are needed to ensure solutions of sufficient quality to be useful, and soundly theoretically based. This book addresses the common techniques required for all the applications, and is thus truly interdisciplinary. Thiscollection of surveyarticlesfocusses onthe large inverse problems commonly arising in simulation and forecasting in the earth sciences. For example, operational weather forecasting models have between 107 and 108 degrees of freedom. Even so, these degrees of freedom represent grossly space-time averaged properties of the atmosphere. Accurate forecasts require accurate initial conditions. With recent developments in satellite data, there are between 106 and 107 observations each day. However, while these also represent space-time averaged properties, the averaging implicit in the measurements is quite different from that used in the models. In atmosphere and ocean applications, there is a physically-based model available which can be used to regularise the problem. We assume that there is a set of observations with known error characteristics available over a period of time. The basic deterministic technique is to fit a model trajectory to the observations over a period of time to within the observation error. Since the model is not perfect the model trajectory has to be corrected, which defines the data assimilation problem. The stochastic view can be expressed by using an ensemble of model trajectories, and calculating corrections to both the mean value and the spread which allow the observations to be fitted by each ensemble member. In other areas of earth science, only the structure of the model formulation itself is known and the aim is to use the past observation history to determine the unknown model parameters. The book records the achievements of Workshop2 "Large-Scale Inverse Problems and Applications in the Earth Sciences". Itinvolves experts in the theory of inverse problems together with experts working on both theoretical and practical aspects of the techniques by which large inverse problems arise in the earth sciences.

An Introduction to Data Analysis and Uncertainty Quantification for Inverse Problems

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Publisher : SIAM
ISBN 13 : 1611974917
Total Pages : 275 pages
Book Rating : 4.6/5 (119 download)

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Book Synopsis An Introduction to Data Analysis and Uncertainty Quantification for Inverse Problems by : Luis Tenorio

Download or read book An Introduction to Data Analysis and Uncertainty Quantification for Inverse Problems written by Luis Tenorio and published by SIAM. This book was released on 2017-07-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inverse problems are found in many applications, such as medical imaging, engineering, astronomy, and geophysics, among others. To solve an inverse problem is to recover an object from noisy, usually indirect observations. Solutions to inverse problems are subject to many potential sources of error introduced by approximate mathematical models, regularization methods, numerical approximations for efficient computations, noisy data, and limitations in the number of observations; thus it is important to include an assessment of the uncertainties as part of the solution. Such assessment is interdisciplinary by nature, as it requires, in addition to knowledge of the particular application, methods from applied mathematics, probability, and statistics. This book bridges applied mathematics and statistics by providing a basic introduction to probability and statistics for uncertainty quantification in the context of inverse problems, as well as an introduction to statistical regularization of inverse problems. The author covers basic statistical inference, introduces the framework of ill-posed inverse problems, and explains statistical questions that arise in their applications. An Introduction to Data Analysis and Uncertainty Quantification for Inverse Problems?includes many examples that explain techniques which are useful to address general problems arising in uncertainty quantification, Bayesian and non-Bayesian statistical methods and discussions of their complementary roles, and analysis of a real data set to illustrate the methodology covered throughout the book.

Computational Methods for Inverse Problems

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Publisher : SIAM
ISBN 13 : 0898717574
Total Pages : 195 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Computational Methods for Inverse Problems by : Curtis R. Vogel

Download or read book Computational Methods for Inverse Problems written by Curtis R. Vogel and published by SIAM. This book was released on 2002-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a basic understanding of both the underlying mathematics and the computational methods used to solve inverse problems.

Nonlinear Model Reduction for Uncertainty Quantification in Large-scale Inverse Problems

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Publisher :
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.:/5 (244 download)

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Book Synopsis Nonlinear Model Reduction for Uncertainty Quantification in Large-scale Inverse Problems by : David Galbally

Download or read book Nonlinear Model Reduction for Uncertainty Quantification in Large-scale Inverse Problems written by David Galbally and published by . This book was released on 2008 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Cont) The extreme computational cost of the Bayesian framework approach for inferring the values of the inputs that generated a given set of empirically measured outputs often precludes its use in practical applications. In this thesis we show that using a reduced order model for running the Markov.

Princeton Companion to Applied Mathematics

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Publisher : Princeton University Press
ISBN 13 : 0691150397
Total Pages : 1014 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis Princeton Companion to Applied Mathematics by : Nicholas J. Higham

Download or read book Princeton Companion to Applied Mathematics written by Nicholas J. Higham and published by Princeton University Press. This book was released on 2015-09-09 with total page 1014 pages. Available in PDF, EPUB and Kindle. Book excerpt: The must-have compendium on applied mathematics This is the most authoritative and accessible single-volume reference book on applied mathematics. Featuring numerous entries by leading experts and organized thematically, it introduces readers to applied mathematics and its uses; explains key concepts; describes important equations, laws, and functions; looks at exciting areas of research; covers modeling and simulation; explores areas of application; and more. Modeled on the popular Princeton Companion to Mathematics, this volume is an indispensable resource for undergraduate and graduate students, researchers, and practitioners in other disciplines seeking a user-friendly reference book on applied mathematics. Features nearly 200 entries organized thematically and written by an international team of distinguished contributors Presents the major ideas and branches of applied mathematics in a clear and accessible way Explains important mathematical concepts, methods, equations, and applications Introduces the language of applied mathematics and the goals of applied mathematical research Gives a wide range of examples of mathematical modeling Covers continuum mechanics, dynamical systems, numerical analysis, discrete and combinatorial mathematics, mathematical physics, and much more Explores the connections between applied mathematics and other disciplines Includes suggestions for further reading, cross-references, and a comprehensive index

Quantifying Uncertainties in Inverse Problems

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (982 download)

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Book Synopsis Quantifying Uncertainties in Inverse Problems by :

Download or read book Quantifying Uncertainties in Inverse Problems written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bayesian Approach to Inverse Problems

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Publisher : John Wiley & Sons
ISBN 13 : 111862369X
Total Pages : 322 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Bayesian Approach to Inverse Problems by : Jérôme Idier

Download or read book Bayesian Approach to Inverse Problems written by Jérôme Idier and published by John Wiley & Sons. This book was released on 2013-03-01 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many scientific, medical or engineering problems raise the issue of recovering some physical quantities from indirect measurements; for instance, detecting or quantifying flaws or cracks within a material from acoustic or electromagnetic measurements at its surface is an essential problem of non-destructive evaluation. The concept of inverse problems precisely originates from the idea of inverting the laws of physics to recover a quantity of interest from measurable data. Unfortunately, most inverse problems are ill-posed, which means that precise and stable solutions are not easy to devise. Regularization is the key concept to solve inverse problems. The goal of this book is to deal with inverse problems and regularized solutions using the Bayesian statistical tools, with a particular view to signal and image estimation. The first three chapters bring the theoretical notions that make it possible to cast inverse problems within a mathematical framework. The next three chapters address the fundamental inverse problem of deconvolution in a comprehensive manner. Chapters 7 and 8 deal with advanced statistical questions linked to image estimation. In the last five chapters, the main tools introduced in the previous chapters are put into a practical context in important applicative areas, such as astronomy or medical imaging.

Uncertainty Quantification

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Publisher : Springer
ISBN 13 : 3319543393
Total Pages : 344 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Uncertainty Quantification by : Christian Soize

Download or read book Uncertainty Quantification written by Christian Soize and published by Springer. This book was released on 2017-04-24 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fundamental notions and advanced mathematical tools in the stochastic modeling of uncertainties and their quantification for large-scale computational models in sciences and engineering. In particular, it focuses in parametric uncertainties, and non-parametric uncertainties with applications from the structural dynamics and vibroacoustics of complex mechanical systems, from micromechanics and multiscale mechanics of heterogeneous materials. Resulting from a course developed by the author, the book begins with a description of the fundamental mathematical tools of probability and statistics that are directly useful for uncertainty quantification. It proceeds with a well carried out description of some basic and advanced methods for constructing stochastic models of uncertainties, paying particular attention to the problem of calibrating and identifying a stochastic model of uncertainty when experimental data is available. This book is intended to be a graduate-level textbook for students as well as professionals interested in the theory, computation, and applications of risk and prediction in science and engineering fields.

Inverse Problem Theory and Methods for Model Parameter Estimation

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Publisher : SIAM
ISBN 13 : 9780898717921
Total Pages : 349 pages
Book Rating : 4.7/5 (179 download)

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Book Synopsis Inverse Problem Theory and Methods for Model Parameter Estimation by : Albert Tarantola

Download or read book Inverse Problem Theory and Methods for Model Parameter Estimation written by Albert Tarantola and published by SIAM. This book was released on 2005-01-01 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the prediction of observations is a forward problem, the use of actual observations to infer the properties of a model is an inverse problem. Inverse problems are difficult because they may not have a unique solution. The description of uncertainties plays a central role in the theory, which is based on probability theory. This book proposes a general approach that is valid for linear as well as for nonlinear problems. The philosophy is essentially probabilistic and allows the reader to understand the basic difficulties appearing in the resolution of inverse problems. The book attempts to explain how a method of acquisition of information can be applied to actual real-world problems, and many of the arguments are heuristic.

Inverse Problems and Large-Scale Computations

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Publisher : Springer Science & Business Media
ISBN 13 : 3319006606
Total Pages : 223 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Inverse Problems and Large-Scale Computations by : Larisa Beilina

Download or read book Inverse Problems and Large-Scale Computations written by Larisa Beilina and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a result of two international workshops, namely the Second Annual Workshop on Inverse Problems and the Workshop on Large-Scale Modeling, held jointly in Sunne, Sweden from May 1-6 2012. The subject of the inverse problems workshop was to present new analytical developments and new numerical methods for solutions of inverse problems. The objective of the large-scale modeling workshop was to identify large-scale problems arising in various fields of science and technology and covering all possible applications, with a particular focus on urgent problems in theoretical and applied electromagnetics. The workshops brought together scholars, professionals, mathematicians, and programmers and specialists working in large-scale modeling problems. The contributions in this volume are reflective of these themes and will be beneficial to researchers in this area.

Novel Algorithms for Uncertainty Quantification in Large Scale Systems

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Publisher :
ISBN 13 :
Total Pages : 354 pages
Book Rating : 4.:/5 (119 download)

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Book Synopsis Novel Algorithms for Uncertainty Quantification in Large Scale Systems by : Siddhant Wahal

Download or read book Novel Algorithms for Uncertainty Quantification in Large Scale Systems written by Siddhant Wahal and published by . This book was released on 2020 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uncertainty Quantification (UQ) algorithms are of increasing significance in science and engineering. The process of modeling physical reality on computers is rife with uncertainties. These uncertainties get propagated through the computer model, leading to uncertain outputs. As decision-makers from every facet of society come to increasingly rely on computer predictions, the need to characterize this uncertainty has never been greater. However, doing so efficiently remains challenging. This is primarily because computer models are often time consuming to run and because their inputs live in high-dimensional spaces that are difficult to explore. In this thesis, we seek to address this challenge in the context of two UQ problems. In the first UQ problem, we study rare-event simulation: given a smooth non-linear map with uncertain inputs, what is the probability that the output evaluates inside a specified interval? Standard statistical approaches for computing this probability, such as the Monte Carlo method, become computationally inefficient as the event under consideration becomes rare. To address this inefficiency, we present two Importance Sampling (IS) algorithms. Our first algorithm, called the Bayesian Inverse Monte Carlo (BIMC) method, relies on solving a fictitious Bayesian inverse problem. The solution of the inverse problem yields a posterior PDF, a local Gaussian approximation to which serves as the importance sampling density. We subject BIMC to rigorous theoretical and experimental analysis, which establishes that BIMC can lead to speedups of several orders-of-magnitude (over the Monte Carlo method) when the forward map is nearly affine, or weakly non-linear. When these conditions are violated, that is, when the forward map is significantly nonlinear, BIMC leads to a poor-quality IS distribution. Motivated by these limitations, we propose modifications to BIMC. The modified algorithm, which we term Adaptive-BIMC (A-BIMC), proceeds in two stages. The first stage roughly identifies those regions in input space that trigger a rare event. The second stage then refines the approximation from the first stage of the algorithm. We study A-BIMC’s performance on synthetic problems and demonstrate that its performance doesn’t depend on how small the target probability is. Rather it depends on the nonlinearity of the input-output map. Through these experiments, we also find that A-BIMC’s performance deteriorates with increasing ambient dimensionality of the problem. To address this issue, we lay the foundation for a general dimension reduction strategy for rare-event probability estimation. The second UQ problem concerns the statistical calibration of model inputs from observed data, with the ultimate aim of issuing uncertainty-equipped predictions of a Quantity-of- Interest (QoI). The physical system that we study here is a hydrocarbon reservoir containing geological faults. Operational decisions concerning the reservoir rely on predictions of financial summaries of the reservoir, such as its Net Present Value. These summaries depend on the nature of fluid flow within the reservoir, which is itself controlled by the extent to which an individual fault inhibits or facilitates flow. This fault property, known as the fault transmissibility, isn’t directly measurable and must be calibrated using production data. Here, we design and analyze a complete data-to-prediction workflow to quantify post-calibration uncertainties. We also discuss how these uncertainties change under different reservoir conditions

Data-driven Reduction Strategies for Bayesian Inverse Problems

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Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Data-driven Reduction Strategies for Bayesian Inverse Problems by : Ellen Brooke Le

Download or read book Data-driven Reduction Strategies for Bayesian Inverse Problems written by Ellen Brooke Le and published by . This book was released on 2018 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: A persistent central challenge in computational science and engineering (CSE), with both national and global security implications, is the efficient solution of large-scale Bayesian inverse problems. These problems range from estimating material parameters in subsurface simulations to estimating phenomenological parameters in climate models. Despite recent progress, our ability to quantify uncertainties and solve large-scale inverse problems lags well behind our ability to develop the governing forward simulations. Inverse problems present unique computational challenges that are only magnified as we include larger observational data sets and demand higher-resolution parameter estimates. Even with the current state-of-the-art, solving deterministic large-scale inverse problems is prohibitively expensive. Large-scale uncertainty quantification (UQ), cast in the Bayesian inversion framework, is thus rendered intractable. To conquer these challenges, new methods that target the root causes of computational complexity are needed. In this dissertation, we propose data driven strategies for overcoming this "curse of di- mensionality." First, we address the computational complexity induced in large-scale inverse problems by high-dimensional observational data. We propose a randomized misfit approach (RMA), which uses random projections--quasi-orthogonal, information-preserving transformations--to map the high-dimensional data-misfit vector to a low dimensional space. We provide the first theoretical explanation for why randomized misfit methods are successful in practice with a small reduced data-misfit dimension (n = O(1)). Next, we develop the randomized geostatistical approach (RGA) for Bayesian sub- surface inverse problems with high-dimensional data. We show that the RGA is able to resolve transient groundwater inverse problems with noisy observed data dimensions up to 107, whereas a comparison method fails due to out-of-memory errors. Finally, we address the solution of Bayesian inverse problems with spatially localized data. The motivation is CSE applications that would gain from high-fidelity estimation over a smaller data-local domain, versus expensive and uncertain estimation over the full simulation domain. We propose several truncated domain inversion methods using domain decomposition theory to build model-informed artificial boundary conditions. Numerical investigations of MAP estimation and sampling demonstrate improved fidelity and fewer partial differential equation (PDE) solves with our truncated methods.

Assessing the Reliability of Complex Models

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Publisher : National Academies Press
ISBN 13 : 0309256348
Total Pages : 144 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Assessing the Reliability of Complex Models by : National Research Council

Download or read book Assessing the Reliability of Complex Models written by National Research Council and published by National Academies Press. This book was released on 2012-07-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computing hardware and algorithms have dramatically improved the ability to simulate complex processes computationally. Today's simulation capabilities offer the prospect of addressing questions that in the past could be addressed only by resource-intensive experimentation, if at all. Assessing the Reliability of Complex Models recognizes the ubiquity of uncertainty in computational estimates of reality and the necessity for its quantification. As computational science and engineering have matured, the process of quantifying or bounding uncertainties in a computational estimate of a physical quality of interest has evolved into a small set of interdependent tasks: verification, validation, and uncertainty of quantification (VVUQ). In recognition of the increasing importance of computational simulation and the increasing need to assess uncertainties in computational results, the National Research Council was asked to study the mathematical foundations of VVUQ and to recommend steps that will ultimately lead to improved processes. Assessing the Reliability of Complex Models discusses changes in education of professionals and dissemination of information that should enhance the ability of future VVUQ practitioners to improve and properly apply VVUQ methodologies to difficult problems, enhance the ability of VVUQ customers to understand VVUQ results and use them to make informed decisions, and enhance the ability of all VVUQ stakeholders to communicate with each other. This report is an essential resource for all decision and policy makers in the field, students, stakeholders, UQ experts, and VVUQ educators and practitioners.