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Jacked 2015 6
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Download or read book Jacked (2015-) #6 written by Eric Kripke and published by Vertigo. This book was released on 2016-04-27 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can Josh be a hero without being super? Will he still have a family to go back to? One way or the other, kicking an addiction proves harder than kicking some guys in the face as JACKED reaches its shocking conclusion.
Download or read book Jacked (2015-) #1 written by Eric Kripke and published by Vertigo. This book was released on with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eric Kripke (creator of Supernatural) teams up with Vertigo veterans John Higgins (HELLBLAZER) and Glenn Fabry (PREACHER) to bring you a very Vertigo take on the modern superhero in this six-issue miniseries. Josh Jaffe, a neurotic family man mid-midlife crisis, buys an online "smart pill" to increase his focus and jolt him out of his slump. But to Josh's surprise, the pill gives him incredible strength and power-but its cost is that it's extremely addictive. This irreverent and brutally realistic story examines both the mighty highs and humiliating lows of being a real-life superhero.
Download or read book Jacked Vol. 1 written by Eric Kripke and published by Vertigo. This book was released on 2016-06-07 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eric Kripke (creator of the hit TV series SUPERNATURAL) teams up with Vertigo veterans John Higgins (HELLBLAZER) and Glenn Fabry (PREACHER) to bring you a very Vertigo take on the modern superhero in this new graphic novel thriller. Josh Jaffe, a neurotic family man mid-midlife crisis, purchase a "smart pill" to increase his focus and jolt him out of his slump. But to Josh's surprise, the pill gives him incredible strength and power-at the cost of being extremely addictive. This irreverent and brutally realistic story examines both the mighty highs and humiliating lows of being a real-life superhero. Collects JACKED #1-6.
Book Synopsis Potential Therapeutic Strategies for Muscular Dystrophy by : Gisela Gaina
Download or read book Potential Therapeutic Strategies for Muscular Dystrophy written by Gisela Gaina and published by BoD – Books on Demand. This book was released on 2023-11-02 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a comprehensive overview of the different forms of muscular dystrophy (MD), including potential therapeutic interventions and the advantages associated with repurposing pharmaceuticals for treating these conditions. In addition, the book examines the effects of physical training on improving symptoms as well as patient quality of life and life span. The target audience of this book comprises students, researchers, and doctors with an interest in the field of muscular dystrophy.
Book Synopsis Background and Management of Muscular Atrophy by : Julianna Cseri
Download or read book Background and Management of Muscular Atrophy written by Julianna Cseri and published by BoD – Books on Demand. This book was released on 2021-03-03 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: A healthy skeletal musculature is necessary for a good quality of life and is important in sports. The loss of skeletal muscle mass leads to severe clinical complications and alters daily functioning. The aim of this book is to give an overview of skeletal muscle atrophy including pathomechanism, clinical characters, and the tools for prevention and treatment. Skeletal muscle atrophy can develop due to neurogenic or myogenic reasons, and frequently appears as an age-dependent disorder (sarcopenia). The studies of theoretical background give promising perspectives to prevent and treat muscle atrophy. The book is recommended to scientists, practitioners, students, sportsmen, and everybody who is interested in the normal and impaired function of the skeletal muscle.
Book Synopsis Spinal Muscular Atrophy by : Charlotte J Sumner
Download or read book Spinal Muscular Atrophy written by Charlotte J Sumner and published by Academic Press. This book was released on 2016-10-24 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA Includes outstanding questions and perspectives for future investigations and key references for additional detailed study
Book Synopsis Muscular Dystrophy by : Gisela Gaina
Download or read book Muscular Dystrophy written by Gisela Gaina and published by BoD – Books on Demand. This book was released on 2020-12-23 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscular Dystrophy - Research Update and Therapeutic Strategies is for students, researchers, and clinicians interested in muscular dystrophies who want to improve their knowledge of these complex genetic diseases. The book includes information about the genetics of various types of muscular dystrophies as well as explores new and current therapeutic strategies that aim to ameliorate symptoms and improve patients’ quality of life and life expectancy. In addition, this book reviews information on current clinical trials for muscular dystrophies and presents a framework for what to consider during the design of these trials.
Book Synopsis Muscular Dystrophies by : Kunihiro Sakuma
Download or read book Muscular Dystrophies written by Kunihiro Sakuma and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skeletal muscle is a highly plastic organ that is modulated by various pathways controlling protein turnover. Muscle loss is common in muscular dystrophy, in which marked loss of various proteins such as the dystrophin-glycoprotein complex occurs around muscle fibers. This book provides a comprehensive overview of the various muscular dystrophies, including characteristics, diagnosis, and classification. General treatment of drugs (e.g. corticosteroids) and physical therapy for muscular dystrophies are discussed. In addition, current applications for cell and tissue engineering using muscle stem cells or gene therapy are introduced. This book also deals with the recent advances in appropriate models of drug screening using cell cultures or mammalian organs in vitro in this field.
Book Synopsis Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach by : Luciano Merlini
Download or read book Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach written by Luciano Merlini and published by Frontiers Media SA. This book was released on 2016-01-18 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.
Book Synopsis Recent Advances in Stem Cells by : Essam M. Abdelalim
Download or read book Recent Advances in Stem Cells written by Essam M. Abdelalim and published by Springer. This book was released on 2016-09-14 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores recent advances in the use of pluripotent stem cells (PSCs) and adult stem cells (ASCs) in basic and clinical applications. The chapters discuss use of PSCs for drug screening, genome editing, modeling of kidney, motor neuron diseases, and diabetes as well as their application in cancer; ASCs are discussed in the contexts of banking of umbilical cord stem cells, use of multipotential stromal cells (MSCs) for bone repair, cellular interactions during fracture repair stages, and therapeutic applications of neural crest stem cells and lung stem cells. The text is organized by sections dealing with PSCs and ASCs specifically, presenting the reader with a comprehensive examination of both these forms of stem cells. Expertly authored and drawing from a wealth of international perspectives, Recent Advances in Stem Cells: From Basic Research to Clinical Applications presents a succinct yet detailed review of cutting-edge research in this rapidly expanding field. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is essential reading for academics, researchers, and clinicians in the fields of cell biology, genetics, nephrology, osteology, oncology, and pulmonology.
Book Synopsis Duchenne Muscular Dystrophy - A Guide by : Dr.S.Daniel Rajasundaram
Download or read book Duchenne Muscular Dystrophy - A Guide written by Dr.S.Daniel Rajasundaram and published by Shanlax Publications. This book was released on with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book entitled, “Duchenne Muscular Dystrophy- A Guide”, is a comprehensive and easyguide to parents, other family members and care takers which presents the classification of Muscular Dystrophies. However Duchenne Muscular Dystrophy (DMD) alone is elaborated in detail, as DMD is the predominant Genetic Disorder which is widely observed in our society among various group of people in various geographical areas of the country and even world. This book presents a structured management methods for the care takers, while details the necessary information and guidelines to the parents of the DMD patients regarding, Lungs and Breath Care, Food and Digestive Care, Spinal Cord Care, Heart related Care, Medications and Steroid related Care etc. Symptoms and Stages of DMD are also presented. This book emphasizes the need for providing the comfortable areas for the DMD patient to be explored. A brief overview about the adaptability and movement issues of the patients are listed in a crispy way. This will be helpful to the teachers while the patients are at schools. Meanwhile this will be beneficial to the parents while they bring their wards to some public areas. Finally this guide accentuates the key points to make the society free from Muscular Dystrophy.
Book Synopsis Clinical Cardiogenetics by : Hubert F. Baars
Download or read book Clinical Cardiogenetics written by Hubert F. Baars and published by Springer. This book was released on 2016-11-30 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis and treatment of each cardiogenetic disease separately. Therapy advice, ICD indications, indications for and manner of further family investigation will all be covered, while each chapter will also contain take-home messages to reinforce the key points. The chapters reviewing the different diseases will each contain a table describing the genes involved in each. Each chapter will also contain specific illustrations, cumulatively giving a complete, practical review of each cardiogenetic disease separately. Special emphasis will be given to advice on how to diagnose and manage cardiogenetic diseases in clinical practice, which genes should be investigated and why, and the pros and cons of genetic testing. Guidelines for investigation in families with sudden cardiac death at young age will also be included. This book will be written for the general cardiologist and the clinical geneticist who is involved in cardiac patients and will provide answers to question such as: Which genes are involved and which mutations? What is the effect of the mutation at cellular level? Which genes should be tested and why? What is the value of a molecular diagnosis? Does it influence therapy? When should the first degree relatives be tested and in which way?
Book Synopsis Mechanisms in Duchenne Muscular Dystrophy Pathophysiology and Treatment by : Atsushi Asakura
Download or read book Mechanisms in Duchenne Muscular Dystrophy Pathophysiology and Treatment written by Atsushi Asakura and published by Frontiers Media SA. This book was released on 2023-09-07 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Muscular Dystrophy by : Raymond A. Huml
Download or read book Muscular Dystrophy written by Raymond A. Huml and published by Springer. This book was released on 2015-07-16 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical and concise guide offers an overview of muscular dystrophy's complicated features, treatment options and general resources. New treatments and a greater understanding of proteins and structures associated with MD are discussed along with long term patient care. Also included are clinical and developmental challenges within the current regulatory landscape and recent scientific and clinical advances. Muscular Dystrophy offers clinicians, researchers, pharmaceutical executives and patient advocacy groups an easy-to-read reference that provides the necessary perspectives of the care giver and patient.
Book Synopsis Muscular Dystrophy Therapeutics by : Rika Maruyama
Download or read book Muscular Dystrophy Therapeutics written by Rika Maruyama and published by Springer Nature. This book was released on 2022-11-18 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book presents a comprehensive collection of state-of-the-art protocols on muscular dystrophy therapeutics, covering therapeutics using antisense oligonucleotides, gene replacement, genome editing, small molecules, stem cells, and antibodies. Written by leaders in the field, the volume explores techniques that are currently in use and are starting an exciting therapeutic revolution in muscular dystrophy. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Muscular Dystrophy Therapeutics: Methods and Protocols serves as an ideal resource to inspire readers and provide tips, strategies, and advice to develop new therapeutic technologies for this group of diseases.
Book Synopsis A Guide to Duchenne Muscular Dystrophy by : Janet Hoskin
Download or read book A Guide to Duchenne Muscular Dystrophy written by Janet Hoskin and published by Jessica Kingsley Publishers. This book was released on 2017-12-14 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prognosis for individuals with Duchenne Muscular Dystrophy (DMD) is improving, with some men with DMD living into their 30s and 40s. More vital than ever, this book helps teachers and parents to support children and young people with DMD with their education and transition into adulthood. Leading experts on DMD explain Duchenne and its impact in easy-to-understand terms. Going beyond physical management, particular focus is put on learning and behavioural issues, including speech delay and difficulty learning to read, as well as common comorbid conditions, such as ADHD, autism and OCD. Raising aspirations, the book gives guidance on effective support in the classroom and advice on the transition to adulthood, employment and independent living.
Book Synopsis Genetic testing in pediatric disorders by : Merlin G. Butler
Download or read book Genetic testing in pediatric disorders written by Merlin G. Butler and published by Frontiers Media SA. This book was released on 2024-01-03 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: