Introduction To Translational Cardiovascular Research

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Introduction to Translational Cardiovascular Research

Author : Dennis V. Cokkinos
Publisher : Springer
ISBN 13 : 3319087983
Total Pages : 609 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Introduction to Translational Cardiovascular Research by : Dennis V. Cokkinos

Download or read book Introduction to Translational Cardiovascular Research written by Dennis V. Cokkinos and published by Springer. This book was released on 2014-11-06 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and the hypothalamic-pituitary-adrenal axis, while covering genetic polymorphisms both generally and specifically as regards the vascular endothelium and the use of microRNAs. As such, this book will be relevant to young physicians, nurses and other scientists engaged in the clinical cardiovascular field who want to added research-oriented dimension to their efforts towards better understanding and practicing of medicine. It also aims to attract young basic researchers who want to develop a better comprehension of the organism as a whole, man or animal, that they are investigating.

Translational Cardiology

Author : Cam Patterson
Publisher : Springer Science & Business Media
ISBN 13 : 1617798916
Total Pages : 556 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Translational Cardiology by : Cam Patterson

Download or read book Translational Cardiology written by Cam Patterson and published by Springer Science & Business Media. This book was released on 2012-07-04 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.

Encyclopedia of Cardiovascular Research and Medicine

Author :
Publisher : Elsevier
ISBN 13 : 012805154X
Total Pages : 2800 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Encyclopedia of Cardiovascular Research and Medicine by :

Download or read book Encyclopedia of Cardiovascular Research and Medicine written by and published by Elsevier. This book was released on 2017-11-27 with total page 2800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Cardiovascular Research and Medicine offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focused basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine. Presents comprehensive coverage of every aspect of cardiovascular medicine and research Offers readers a broad, interdisciplinary overview of the concepts in cardiovascular research and medicine with applications across biomedical research Includes reputable, foundational content on genetics, cancer, immunology, cell biology and molecular biology Provides a multi-media enriched color-illustrated text with high quality images, graphs and tables.

Myocardial Preservation

Author : Dennis V. Cokkinos
Publisher : Springer
ISBN 13 : 3319981862
Total Pages : 405 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Myocardial Preservation by : Dennis V. Cokkinos

Download or read book Myocardial Preservation written by Dennis V. Cokkinos and published by Springer. This book was released on 2019-01-28 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.

Translational Cardiology

Author :
Publisher : Springer
ISBN 13 : 9781617798924
Total Pages : 560 pages
Book Rating : 4.7/5 (989 download)

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Book Synopsis Translational Cardiology by :

Download or read book Translational Cardiology written by and published by Springer. This book was released on 2012-08-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiovascular Research

Author : Gerard Pasterkamp
Publisher : Springer Science & Business Media
ISBN 13 : 0387233296
Total Pages : 261 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Cardiovascular Research by : Gerard Pasterkamp

Download or read book Cardiovascular Research written by Gerard Pasterkamp and published by Springer Science & Business Media. This book was released on 2007-06-10 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, technical improvements have changed the inventory of many research laboratories. New techniques and discoveries continuously give rise to observations that result in the de?nition of new research objectives. In the past, - search departments were clearly demarcated. Nowadays, technology that is shared by all lines of research stimulates convergence of research interests. This also - plies to cardiovascular research. Vascular occlusive disease is now core business for researchers employed by cardiology, vascular surgery, vascular medicine, - diology, cell biology, chemistry, physiology, and many other areas. Knowledge on actual research development is shared by researchers with different skills. It is sometimes dif?cult to acquire expertise when a researcher feels his experimental work could be improved by introducing a new research technique. In this book, the investigator will ?nd an overview of recent developments that are relevant for research in general but cardiovascular research in particular. Genomics, p- teomics, microarray, RNAi, stem cells, and progenitor cells are just some phrases that have become increasingly prevalent in literature in the last few years and that are recognized by many, but are fully understood by few. In this book, experts share the most appreciated new developments and techniques in cardiovascular research. We hope that this book will help the reader who is working in the ?eld of cardiovascular research to understand and critically appreciate current research, and that it will help improve the quality of experimental work. Dr G.

Clinical and Translational Science

Author : David Robertson
Publisher : Academic Press
ISBN 13 : 012802111X
Total Pages : 812 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Clinical and Translational Science by : David Robertson

Download or read book Clinical and Translational Science written by David Robertson and published by Academic Press. This book was released on 2016-11-25 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Translational Research in Coronary Artery Disease

Author : Wilbert S. Aronow
Publisher : Academic Press
ISBN 13 : 0128026057
Total Pages : 244 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Research in Coronary Artery Disease by : Wilbert S. Aronow

Download or read book Translational Research in Coronary Artery Disease written by Wilbert S. Aronow and published by Academic Press. This book was released on 2015-10-29 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair

Author : Nabil Dib
Publisher : Springer Science & Business Media
ISBN 13 : 038730939X
Total Pages : 332 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair by : Nabil Dib

Download or read book Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair written by Nabil Dib and published by Springer Science & Business Media. This book was released on 2006-04-09 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: In excess of 7 million people worldwide die of coronary heart disease each year. Only one-third of these heart attack victims recover completely. The remainder suffer the consequences of myocardial infarction and its ill fated remodeling process, resulting in chronic congestive heart failure. This malady alone is the leading cause of hospital admissions in the United States. New breakthroughs in stem cell therapy and tissue engineering have promised to reverse this dismal outcome by cardiovascular repair. World authorities, including scientists and regulatory authorities, have joined in a collaborative effort to present for the reader the first collective review of stem cell therapy for the treatment of cardiovascular disease. These contributions in basic science, pre-clinical and clinical experience guided by the regulatory pathways, assure a rapid course of translational research and clinical trials. The contents of this publication will become a prerequisite for those preparing to meet the challenges of this exciting and potentially rewarding field of stem cell research.

Practical Methods in Cardiovascular Research

Author : Stefan Dhein
Publisher : Springer
ISBN 13 : 3540265740
Total Pages : 1010 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Practical Methods in Cardiovascular Research by : Stefan Dhein

Download or read book Practical Methods in Cardiovascular Research written by Stefan Dhein and published by Springer. This book was released on 2006-02-28 with total page 1010 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists working or planning to work in the field of cardiovascular research will welcome Methods in Cardiovascular Research as the reference book they have been waiting for. Not only general aspects of cardiovascular research are well presented but also detailed descriptions of methods, protocols and practical examples. Written by leading scientists in their field, chapters cover classical methods such as the Langendorff heart or working heart models as well as numerous new techniques and methods. Newcomers and experienced researchers alike will benefit from the troubleshooting guide in each chapter, the extensive reference lists for advanced reading and the great practical experience of the authors. Methods in Cardiovascular Research is a "must have" for anybody with an interest in cardiovascular research.

The Role of Physical Fitness on Cardiovascular Responses to Stress

Author : Arto J Hautala
Publisher : Frontiers Media SA
ISBN 13 : 2889194639
Total Pages : 96 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis The Role of Physical Fitness on Cardiovascular Responses to Stress by : Arto J Hautala

Download or read book The Role of Physical Fitness on Cardiovascular Responses to Stress written by Arto J Hautala and published by Frontiers Media SA. This book was released on 2015-03-12 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular responses to physical and/ or mental stressors has been a topic of great interest for some time. For example, significant changes of cardiovascular control and reactivity have been highlighted as important mechanisms for the protective effect of exercise as a simple and effective, non medical therapy for many pathologies. However, despite the great number of studies performed to date (e.g. >54,000 entries in Pubmed for “cardiovascular stress”), important questions of the role stress has on cardiovascular function still remain. For instance, What factors account for the different cardiovascular responses between mental and physical stressors? How do these different components of the cardiovascular system interact during stress? Which cardiovascular responses to stress are the most important for identifying normal, depressed, and enhanced cardiovascular function? Can these stress-induced responses assist with patient diagnosis and prognosis? What impact does physical fitness have on the relationship between cardiovascular function and health? The current topic examined our current understanding of cardiovascular responses to stress and the significant role that physical fitness has on these responses for improved function and health. Manuscripts focusing on heart rate variability (HRV), heart rate recovery, and other novel cardiovascular assessments were especially encouraged.

Manual of Research Techniques in Cardiovascular Medicine

Author : Hossein Ardehali
Publisher : John Wiley & Sons
ISBN 13 : 1118495136
Total Pages : 1 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Manual of Research Techniques in Cardiovascular Medicine by : Hossein Ardehali

Download or read book Manual of Research Techniques in Cardiovascular Medicine written by Hossein Ardehali and published by John Wiley & Sons. This book was released on 2013-12-16 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: While some research methods or techniques are applicable in several areas of medicine, research in cardiovascular diseases requires knowledge of an increasing array of procedures, techniques and measurements that are highly specialized and unique to this area of investigation. Edited by senior clinical investigators who are recognized leaders in cardiovascular medicine worldwide, this book provides readers with a comprehensive, practical “how-to-do-it” review of best-practice techniques for cardiovascular research.

Zebrafish Model for Biomedical Research

Author : Prasan R. Bhandari
Publisher : Springer Nature
ISBN 13 : 9811652171
Total Pages : 493 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Zebrafish Model for Biomedical Research by : Prasan R. Bhandari

Download or read book Zebrafish Model for Biomedical Research written by Prasan R. Bhandari and published by Springer Nature. This book was released on 2022-05-30 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.

Translational Approach to Heart Failure

Author : Jozef Bartunek
Publisher : Springer Science & Business Media
ISBN 13 : 1461473454
Total Pages : 501 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Translational Approach to Heart Failure by : Jozef Bartunek

Download or read book Translational Approach to Heart Failure written by Jozef Bartunek and published by Springer Science & Business Media. This book was released on 2013-07-13 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: The refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients. However the complex interplay between the clinical presentation and the array of the interventions requires a coordinated multidisciplinary “heart team” approach involving various specialists in the cardiovascular field including clinicians, interventionalists, surgeons and cardiac intensivists. In this book, opinion leaders will review of state-of-the-art management of heart failure with particular emphasis on burning clinical questions and challenges faced by the heart team. New medical and interventional therapies for chronic and acute heart failure are addressed by bridging bench to bedside translation in science and technology into practical clinical application and guidance.

Principles of Translational Science in Medicine

Author : Martin Wehling
Publisher : Academic Press
ISBN 13 : 0128007214
Total Pages : 365 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Translational Science in Medicine by : Martin Wehling

Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Thyroid and Heart

Author : Giorgio Iervasi
Publisher : Springer Nature
ISBN 13 : 3030368718
Total Pages : 436 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Thyroid and Heart by : Giorgio Iervasi

Download or read book Thyroid and Heart written by Giorgio Iervasi and published by Springer Nature. This book was released on 2020-03-19 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects – kidney, hormonal pathways systems, brain, muscle, etc – of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.

Cardiovascular Implications of Stress and Depression

Author : Paul D. Chantler
Publisher : Academic Press
ISBN 13 : 0128150165
Total Pages : 380 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cardiovascular Implications of Stress and Depression by : Paul D. Chantler

Download or read book Cardiovascular Implications of Stress and Depression written by Paul D. Chantler and published by Academic Press. This book was released on 2019-08-27 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Implications of Stress and Depression provides an in-depth examination on how exposure to stress influences risk for cardiovascular disease and how depression is associated with this relationship. This authoritative volume examines causal pathways linking stress, depression and cardiovascular disease. In addition, it provides mechanistic insights into how environmental stress can lead to cardiovascular diseases. Current information about mechanistic factors, clinical and epidemiological aspects, and management issues associated with stress/depression are presented. These insights demonstrate how the mechanisms behind chronic stress and depression lead to cardiovascular diseases. In addition, their role in existing diseases (such as obesity, hypertension, and diabetes) is explored. Provides the latest information on how stress leads to depression and how stress/depression interacts to accelerate cardiovascular diseases, including stroke Delivers insights on how mechanisms of stress/depression affect vasculature Explores how to best research this topic from human and pre-clinical models