Intracellular Mechanisms for Neuritogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387685618
Total Pages : 347 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Intracellular Mechanisms for Neuritogenesis by : Ivan Curtis

Download or read book Intracellular Mechanisms for Neuritogenesis written by Ivan Curtis and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book present in novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction. Its aim is to present this topic to the general readership of neurobiologists and molecular and cellular biologists to further stimulate the interest into this exciting section of neurobiology.

Molecular and Cellular Mechanisms of Synaptopathies: Emerging Synaptic aging-related molecular pathways in Neurological Disorders

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Publisher : Frontiers Media SA
ISBN 13 : 2832542298
Total Pages : 133 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Molecular and Cellular Mechanisms of Synaptopathies: Emerging Synaptic aging-related molecular pathways in Neurological Disorders by : Dario Maschi

Download or read book Molecular and Cellular Mechanisms of Synaptopathies: Emerging Synaptic aging-related molecular pathways in Neurological Disorders written by Dario Maschi and published by Frontiers Media SA. This book was released on 2024-01-11 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synapses are complex, highly specialized biological structures. Therefore, even slight functional disturbance can lead to disruptive brain disorders. Dysfunction of these structures is associated with a variety of aging-related neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. Most synaptopathies compromise complex signaling pathways by progressively affecting the synaptic protein repertoire. Currently, the treatment of most of these pathologies focuses on the mitigation of symptoms; in consequence, further efforts need to be made to elucidate the common molecular culprit and cellular mechanisms underlying the cause of these severe pathologies to serve as therapeutic targets for clinical applications. In this Research Topic, we aim to discuss synaptic dysfunction as a causal factor for aging-related neurodegenerative diseases. Despite the recent technological advances that allow identifying the individual synaptic components affected in these synaptic pathologies, we know little about how they impact the synaptic function. To promote the discussion around the molecular and functional connection, we primarily welcome original research, review, and perspective articles emphasizing the relationship between synaptic function and the proteins or mechanisms affected.

Molecular and Cellular Mechanisms of Neuronal Plasticity

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Publisher : Springer Science & Business Media
ISBN 13 : 1461548691
Total Pages : 229 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular and Cellular Mechanisms of Neuronal Plasticity by : Yigal H. Ehrlich

Download or read book Molecular and Cellular Mechanisms of Neuronal Plasticity written by Yigal H. Ehrlich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate int the storage of information in the brain, its retention for long durations, and its retrieval upon demand. Cells in the nervous system have the capability of undergoing extremely long-lasting alterations in response to hormonal, pharmacological, and environmental stimulations. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of learning and the formation of memories in the brain. This volume presents research areas which have not been highlighted in the past. In addition to studies on the involement of functional proteins in neuronal adaptation, this volume presents recent developments on the critical roles of bioactive lipids and nucleotides in these processes. In addition to the widely studied role of second messengers, a review of studies on extracellular phosphorylation systems operating on the surface of brain neurons is presented.The first section of the volume presents studies of basic mechanisms operating in a wide range of adaptive processes. The second section presents recent advances in investigations that have demonstrated the clinical implications of this research. These include: state of the art use of transgenic models in studies of molecular and cellular mechanisms implicated in familial Alzheimer's disease and Amyotrophic Lateral Sclerosis; studies of specific proteins implicated in Alzheimer's disease, including an adapter that binds to the beta-amyloid precurser protein (beta-APP) and the microtubular protein Tau and its membrane-bound counterpart. The advantages of using cell culture models for elucidating the causes of neuronal degeneration and for identifying mechanisms of neuroprotection are also presented among the chapters in the section on clinical implications.

Branching Morphogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387308733
Total Pages : 255 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Branching Morphogenesis by : Jamie Davies

Download or read book Branching Morphogenesis written by Jamie Davies and published by Springer Science & Business Media. This book was released on 2007-03-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.

International Review of Cytology

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Publisher : Academic Press
ISBN 13 : 0080856918
Total Pages : 317 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis International Review of Cytology by :

Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1994-08-03 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Intracellular Mechanisms of α-Synuclein Processing

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Publisher : Frontiers Media SA
ISBN 13 : 2889715728
Total Pages : 237 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Intracellular Mechanisms of α-Synuclein Processing by : Friederike Zunke

Download or read book Intracellular Mechanisms of α-Synuclein Processing written by Friederike Zunke and published by Frontiers Media SA. This book was released on 2021-11-02 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Models of Schizophrenia

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Publisher : Elsevier
ISBN 13 : 0080962238
Total Pages : 142 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Genetic Models of Schizophrenia by : Akira Sawa

Download or read book Genetic Models of Schizophrenia written by Akira Sawa and published by Elsevier. This book was released on 2009-11-10 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a well-established international series that examines major areas of basic and clinical research within neuroscience (as well as emerging and promising subfields): neuroanatomy, neurophysiology, neuroimaging, neurobiology, neuropharmacology, neuroendocrinology, neuropathology, neuropsychiatry, and neurobehavior. This volume provides a thorough treatment of gene models of schizophrenia, presenting articles from leading contributors in this important area.

Extracellular and Intracellular Signaling

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849731608
Total Pages : 319 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Extracellular and Intracellular Signaling by : James D. Adams

Download or read book Extracellular and Intracellular Signaling written by James D. Adams and published by Royal Society of Chemistry. This book was released on 2011 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.

Serine Proteases and Their Serpin Inhibitors in the Nervous System

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Publisher : Springer Science & Business Media
ISBN 13 : 1468483579
Total Pages : 359 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Serine Proteases and Their Serpin Inhibitors in the Nervous System by : Barry W. Festoff

Download or read book Serine Proteases and Their Serpin Inhibitors in the Nervous System written by Barry W. Festoff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ARW held in Maratea, Italy, July 2-8, 1989

The Autisms

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Publisher : OUP USA
ISBN 13 : 0199732124
Total Pages : 402 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis The Autisms by : Mary Coleman

Download or read book The Autisms written by Mary Coleman and published by OUP USA. This book was released on 2012-01-05 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Biology of the autistic syndromes / Christopher Gillberg, Mary Coleman. 3rd ed. 2000.

Computational Epigenetics and Diseases

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Publisher : Academic Press
ISBN 13 : 0128145145
Total Pages : 452 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Computational Epigenetics and Diseases by :

Download or read book Computational Epigenetics and Diseases written by and published by Academic Press. This book was released on 2019-02-06 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. - Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases - Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA - Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases

Cytoskeleton

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Publisher : BoD – Books on Demand
ISBN 13 : 9535131699
Total Pages : 344 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Cytoskeleton by : Jose C. Jimenez-Lopez

Download or read book Cytoskeleton written by Jose C. Jimenez-Lopez and published by BoD – Books on Demand. This book was released on 2017-05-17 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

Neuronal Morphogenesis

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Publisher : Springer Nature
ISBN 13 : 1071639692
Total Pages : 382 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Neuronal Morphogenesis by : Kazuhito Toyooka

Download or read book Neuronal Morphogenesis written by Kazuhito Toyooka and published by Springer Nature. This book was released on with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structure and Function of the Neural Cell Adhesion Molecule NCAM

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Publisher : Springer Science & Business Media
ISBN 13 : 1441911707
Total Pages : 429 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Structure and Function of the Neural Cell Adhesion Molecule NCAM by : Vladimir Berezin

Download or read book Structure and Function of the Neural Cell Adhesion Molecule NCAM written by Vladimir Berezin and published by Springer Science & Business Media. This book was released on 2009-12-17 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).

Marijuana and Madness

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Publisher : Cambridge University Press
ISBN 13 : 9781139451659
Total Pages : 238 pages
Book Rating : 4.4/5 (516 download)

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Book Synopsis Marijuana and Madness by : David Castle

Download or read book Marijuana and Madness written by David Castle and published by Cambridge University Press. This book was released on 2004-05-27 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana), with particular emphasis on psychotic disorders. It outlines developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illness such as schizophrenia. A number of controversial issues are critically explored, including whether a discrete 'cannabis psychosis' exists, and whether cannabis can actually cause schizophrenia. Effects of cannabis on mood, notably depression, are reviewed, as are its effects on cognition. This book will be of interest to all members of the mental health team, as well as to neuroscientists and those involved in drug and alcohol research.

Factors Affecting Neurodevelopment

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Publisher : Academic Press
ISBN 13 : 0128179872
Total Pages : 686 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Factors Affecting Neurodevelopment by : Colin R Martin

Download or read book Factors Affecting Neurodevelopment written by Colin R Martin and published by Academic Press. This book was released on 2021-05-29 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with proper and abnormal development. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurodevelopment. In addition, the book examines in vitro and in vivo modeling of development with stem cells and model systems. - Provides the most comprehensive coverage of a broad range of topics relating to the neuroscience of development - Features sections on the genetics of developmental conditions and accompanying behavior - Contains an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding in each chapter - Focuses on neurodevelopmental disorders and environmental factors that influence neural development - Includes more than 500 illustrations and tables

Cellular Migration and Formation of Axons and Dendrites

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Publisher : Academic Press
ISBN 13 : 0128144084
Total Pages : 630 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cellular Migration and Formation of Axons and Dendrites by : Bin Chen

Download or read book Cellular Migration and Formation of Axons and Dendrites written by Bin Chen and published by Academic Press. This book was released on 2020-05-29 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Migration and Formation of Neuronal Connections, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. This book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the formation of axons and dendrites and cellular migration. - Features leading experts in various subfields as section editors and article authors - Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship - Includes coverage of mechanisms which regulate the formation of axons and dendrites and cellular migration - Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity