Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Instrumentation For Improving The Spatial Resolution And Sensitivity In Small Animal Positron Emission Tomography
Download Instrumentation For Improving The Spatial Resolution And Sensitivity In Small Animal Positron Emission Tomography full books in PDF, epub, and Kindle. Read online Instrumentation For Improving The Spatial Resolution And Sensitivity In Small Animal Positron Emission Tomography ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Instrumentation for Improving the Spatial Resolution and Sensitivity in Small Animal Positron Emission Tomography by : Sara St. James
Download or read book Instrumentation for Improving the Spatial Resolution and Sensitivity in Small Animal Positron Emission Tomography written by Sara St. James and published by . This book was released on 2010 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy by : Yuji Kuge
Download or read book Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy written by Yuji Kuge and published by Springer. This book was released on 2016-04-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.
Book Synopsis A Very High Spatial Resolution Detector for Small Animal PET. by :
Download or read book A Very High Spatial Resolution Detector for Small Animal PET. written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography (PET) is an in vivo analog of autoradiography and has the potential to become a powerful new tool in imaging biological processes in small laboratory animals. PET imaging of small animals can provide unique information that can help in advancement of human disease models as well as drug development. Clinical PET scanners used for human imaging are bulky, expensive and do not have adequate spatial resolution for small animal studies. Hence, dedicated, low cost instruments are required for conducting small animal studies with higher spatial resolution than what is currently achieved with clinical as well as dedicated small animal PET scanners. The goal of the proposed project is to investigate a new all solid-state detector design for small animal PET imaging. Exceptionally high spatial resolution, good timing resolution, and excellent energy resolution are expected from the proposed detector design. The Phase I project was aimed at demonstrating the feasibility of producing high performance solid-state detectors that provide high sensitivity, spatial resolution, and timing characteristics. Energy resolution characteristics of the new detector were also investigated. The goal of the Phase II project is to advance the promising solid-state detector technology for small animal PET and determine its full potential. Detectors modules will be built and characterized and finally, a bench-top small animal PET system will be assembled and evaluated.
Book Synopsis Small Animal Imaging by : Fabian Kiessling
Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer Science & Business Media. This book was released on 2010-11-29 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small animal imaging has been recognized as an important tool in preclinical research. Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of a suboptimal imaging modality and/or shortcomings in study design, experimental setup, and data evaluation. This textbook is a practical guide to the use of non-invasive imaging in preclinical research. Each of the available imaging modalities is discussed in detail, with the assistance of numerous informative illustrations. In addition, many useful hints are provided on the installation of a small animal unit, study planning, animal handling, and the cost-effective performance of small animal imaging. Cross-calibration methods, data postprocessing, and special imaging applications are also considered in depth. This is the first book to cover all the practical basics in small animal imaging, and it will prove an invaluable aid for researchers, students, and technicians.
Download or read book PET written by Michael E. Phelps and published by Springer Science & Business Media. This book was released on 2006-12-30 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to give the reader a solid understanding of the physics and instrumentation aspects of PET, including how PET data are collected and formed into an image. Topics include basic physics, detector technology used in modern PET scanners, data acquisition, and 3D reconstruction. A variety of modern PET imaging systems are also discussed, including those designed for clinical services and research, as well as small-animal imaging. Methods for evaluating the performance of these systems are also outlined. The book will interest nuclear medicine students, nuclear medicine physicians, and technologists.
Book Synopsis Nuclear Medicine Instrumentation by : Jennifer Prekeges
Download or read book Nuclear Medicine Instrumentation written by Jennifer Prekeges and published by Jones & Bartlett Publishers. This book was released on 2010-10-25 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doody's Book Review - Score: 95, 4 Stars! Nuclear Medicine Instrumentation is the first text to covers instruments vital to nuclear medicine at a technologist’s level. It provides students with concise and straightforward information pertaining to the operation and use of each instrument. It is specifically designed to prepare students for typical scenarios and potential pitfalls they may encounter throughout their careers. Nuclear Medicine Instrumentation is broken into four main parts: • Small Instruments • Gamma Camera • Single Photon Emission Computed Tomography (SPECT) • Positron Emission Tomography (PET) Topics discussed include factors relating to Radiation Measurements, Quality Control of Gamma Cameras, Basic Principles and Image Display Techniques for Single –Photon Emission Computed Technology and much more! Each new print copy of this review guide ncludes an interactive CD-ROM with review questions, answers, and explanations. Please note: Electronic formats of this review guide do not include the CD ROM.
Book Synopsis Nuclear Oncology by : H. William Strauss
Download or read book Nuclear Oncology written by H. William Strauss and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
Book Synopsis Advances in organ-specific PET instrumentation and their clinical and research applications, An Issue of PET Clinics, E-Book by : Abass Alavi
Download or read book Advances in organ-specific PET instrumentation and their clinical and research applications, An Issue of PET Clinics, E-Book written by Abass Alavi and published by Elsevier Health Sciences. This book was released on 2023-11-13 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of PET Clinics, guest editors Drs. Abass Alavi, Habib Zaidi, and Suleman Surti bring their considerable expertise to the topic of Advances in Organ-specific PET Instrumentation and Their Clinical Applications. Top experts cover key topics such as the increasing use of silicon photomultiplier (SiPM) technology, advances in depth-of-interaction (DOI) and time-of-flight (TOF) PET detectors, the use of artificial intelligence technologies for detector development; and more. Contains 11 relevant, practice-oriented topics including advances in PET detectors and readout technologies; whole-gamma imaging; clinical applications of dedicated brain PET; clinical applications of dedicated breast PET; potential clinical applications of dedicated prostate PET; and more. Provides in-depth clinical reviews on advances in organ-specific PET instrumentation and their clinical applications, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Handbook of Small Animal Imaging by : George C. Kagadis
Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2018-09-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Book Synopsis Position-sensitive Solid-state Photomultipliers for Small-animal PET by : Jeffrey P. Schmall
Download or read book Position-sensitive Solid-state Photomultipliers for Small-animal PET written by Jeffrey P. Schmall and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The current generation of small-animal PET systems are being successfully used to understand a wide variety of biological problems, however the limitations in what can be visualized and quantified are readily apparent. The achievable spatial resolution of small- animal PET systems continues to be dominated by the detectors themselves and not by physical effects of positron decay. Prospects of new detector designs using solid-state photomultipliers (SSPM) have recently become available and the goal of this research was to understand the improvements detector designs utilizing SSPMs could bring to the field of small-animal PET. The dissertation work focuses on a new SSPM design, created in collaboration with Radiation Monitoring Devices, Inc. (Watertown, MA), which we refer to as the position-sensitive SSPM (PS-SSPM). The device is manufactured using a complementary-metal-oxide-semiconductor technology, and was designed and optimized for maximum spatial resolution.Two novel large-area PS-SSPMs were evaluated - at the time of production they were the largest area SSPMs ever manufactured - a continuous 10 mm x 10 mm, and a 2 x 2 array of 5 mm x 5 mm PS-SSPMs, both devices covering 1 cm2 area. Application specific electronics were developed and readout strategies were implemented for both large-area detector designs. The detectors were first optimized for operating bias voltage and temperature using a signal to noise analysis developed by our lab group. Their performance was then compared in terms of energy resolution, timing resolution, and spatial decoding ability. It was found that for ultra high spatial resolution applications the 2 x 2 array of 5 mm PS-SSPMs performed much better. Detector designs using a dual-ended readout of high resolution scintillation arrays were then evaluated. Scintillation arrays, composed of individual crystals of dimensions 0.7 mm x 0.7 mm x 20 mm, could be resolved at all depths and a depth of interaction resolution of 3.1 mm was measured; which if translated into a PET system would represent a large improvement in both spatial resolution and sensitivity, compared to current generation systems.
Book Synopsis Small-Animal SPECT Imaging by : Matthew A. Kupinski
Download or read book Small-Animal SPECT Imaging written by Matthew A. Kupinski and published by Springer Science & Business Media. This book was released on 2007-05-27 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.
Book Synopsis Towards High Sensitivity and High Spatial Resolution Positron Emission Tomography Imaging by : Zheng Gu
Download or read book Towards High Sensitivity and High Spatial Resolution Positron Emission Tomography Imaging written by Zheng Gu and published by . This book was released on 2014 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: High sensitivity and high resolution have been pursued as some of the most important research goals for preclinical Positron Emission Tomography (PET) imaging. PETbox4, a new, fully tomographic bench top PET scanner dedicated for mouse imaging, was designed and developed in this work. The aim of the PETbox4 scanner is to achieve very high sensitivity and produce high quality PET tomographic images for molecular imaging based biomedical research. Performance of the prototype PETbox4 system was characterized using the National Electrical Manufacturers Association (NEMA) NU 4-2008 standards. Due to the different characteristics caused by the compact geometrical factors, PETbox4 requires data acquisition protocols that differ from those optimized for conventional large diameter ring systems. In this work the energy window for data acquisitions with PETbox4 was optimized using the Geant4 Application for Tomographic Emission (GATE) simulation. A lower level discriminator (LLD) of 350 keV was proposed as the optimized energy threshold. Pulse pileup is a common problem in multiplexed scintillator detectors readout by resistor divider networks. In this work, a new pileup rejection method named position shift rejection (PSR) is introduced. The PSR method is based on the detection of position shifts on event location as the signal is being integrated. Both simulations and physical measurements show that PSR performs more accurate rejection and avoids erroneous rejection and loss of sensitivity compared to the conventional leading edge rejection (LER) method. A new phoswich DOI Detector with crystal scatter identification capability is being designed and developed for implementation in a next generation small animal PET system at UCLA. Both simulations and measurements were performed to evaluate the characteristics and benefits of the proposed design. In conclusion, these results demonstrate that the proposed detector is feasible and can potentially lead to a high spatial resolution, high sensitivity and DOI PET system.
Book Synopsis Physics of PET and SPECT Imaging by : Magnus Dahlbom
Download or read book Physics of PET and SPECT Imaging written by Magnus Dahlbom and published by CRC Press. This book was released on 2017-02-17 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: PET and SPECT imaging has improved to such a level that they are opening up exciting new horizons in medical diagnosis and treatment. This book provides a complete introduction to fundamentals and the latest progress in the field, including an overview of new scintillator materials and innovations in photodetector development, as well as the latest system designs and image reconstruction algorithms. It begins with basics of PET and SPECT physics, followed by technology advances and computing methods, quantitative techniques, multimodality imaging, instrumentation, pre-clinical and clinical imaging applications.
Download or read book SPECT and SPECT/CT written by Chun K. Kim and published by Thieme. This book was released on 2017-06-14 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: FOUR STARS from Doody's Star Ratings™ Internationally renowned authorities in the field of hybrid imaging contribute firsthand expertise on the practical application of single-photon emission computed tomography (SPECT) and SPECT/CT. By combining clear anatomic markers from CT with functional knowledge from SPECT, SPECT/CT provides added value for patient evaluation and is becoming increasingly prevalent in routine clinical practice. Indeed, hybrid imaging is touted by many as a game changer in nuclear medicine. The first two chapters of this book provide a foundation for understanding SPECT and SPECT/CT technological principles, including the associated radiopharmaceuticals. The remaining chapters detail the utility of SPECT and SPECT/CT in clinical practice including neuroscience and pediatrics, as well as specific pathologies. The book concludes with in-depth discussion of select case studies. Key Features Efficacious use of SPECT and SPECT/CT for primary body systems, including the central nervous, cardiovascular, respiratory, and skeletal systems Value for the assessment of neoplastic disease, infection/inflammation, thyroid and parathyroid gland disorders Fourteen high-quality videos delineate specific techniques and clinical applications Meticulous, four-color graphics clearly elucidate key concepts Illustrative case studies offer educational teaching pearls Together, the concise, evidence-based text and wealth of SPECT/CT images deliver a solid knowledge base, enabling practitioners to learn the effective use of this technology. This must-have book is certain to be an invaluable resource for a diverse spectrum of practicing and trainee clinicians in fields such as radiology, nuclear medicine, and radiation oncology.
Book Synopsis Molecular Imaging of Small Animals by : Habib Zaidi
Download or read book Molecular Imaging of Small Animals written by Habib Zaidi and published by Springer. This book was released on 2014-05-27 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.
Book Synopsis Handbook of Particle Detection and Imaging by : Claus Grupen
Download or read book Handbook of Particle Detection and Imaging written by Claus Grupen and published by Springer Science & Business Media. This book was released on 2012-01-08 with total page 1251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The handbook centers on detection techniques in the field of particle physics, medical imaging and related subjects. It is structured into three parts. The first one is dealing with basic ideas of particle detectors, followed by applications of these devices in high energy physics and other fields. In the last part the large field of medical imaging using similar detection techniques is described. The different chapters of the book are written by world experts in their field. Clear instructions on the detection techniques and principles in terms of relevant operation parameters for scientists and graduate students are given.Detailed tables and diagrams will make this a very useful handbook for the application of these techniques in many different fields like physics, medicine, biology and other areas of natural science.
Book Synopsis Emission Tomography by : Miles N. Wernick
Download or read book Emission Tomography written by Miles N. Wernick and published by Elsevier. This book was released on 2004-12-07 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: PET and SPECT are two of today's most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world's fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.*Contains thorough tutorial treatments, coupled with coverage of advanced topics*Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors*Include color artwork
