Genetics and Evolution of Infectious Diseases

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Publisher : Elsevier
ISBN 13 : 0123848911
Total Pages : 772 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc and published by Elsevier. This book was released on 2010-12-17 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary book is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Infectious Disease and Host-Pathogen Evolution

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Publisher : Cambridge University Press
ISBN 13 : 1139451693
Total Pages : 394 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Infectious Disease and Host-Pathogen Evolution by : Krishna R. Dronamraju

Download or read book Infectious Disease and Host-Pathogen Evolution written by Krishna R. Dronamraju and published by Cambridge University Press. This book was released on 2004-04-05 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, originally published in 2004, is concerned with the links between human evolution and infectious disease. It has long been recognised that an important factor in human evolution has been the struggle against infectious disease and, more recently, it was revealed that complex genetic polymorphisms are the direct result of that struggle.

Infections Disease and Host-pathogen Evolution

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Publisher :
ISBN 13 : 9780511195112
Total Pages : 370 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Infections Disease and Host-pathogen Evolution by : Krishna R. Dronamraju

Download or read book Infections Disease and Host-pathogen Evolution written by Krishna R. Dronamraju and published by . This book was released on 2004 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has long been recognised that an important factor in human evolution has been the struggle against infectious disease and, more recently, it has been revealed that complex genetic polymorphisms are the direct result of that struggle. As molecular biological techniques become more sophisticated, a number of breakthroughs in the area of host-pathogen evolution have led to an increased interest in this field. From the historical beginnings of J.B.S. Haldane's original hypothesis to current research, this book strives to evaluate infectious diseases from an evolutionary perspective. It provides a survey of the latest information regarding host-pathogen evolution related to major infectious diseases and parasitic infections, including malaria, influenza and leishmaniasis. Written by leading authorities in the field, and edited by a former pupil of Haldane, Infectious Disease and Host-Pathogen Evolution will be a valuable reference for those working in related areas of microbiology, parasitology, immunology and infectious disease medicine, as well as genetics, evolutionary biology and epidemiology.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Evolution and Co-Adaptation

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Publisher : National Academies Press
ISBN 13 : 0309131219
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine

Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

Immunology and Evolution of Infectious Disease

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Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)

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Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank

Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

Ending the War Metaphor

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Publisher : National Academies Press
ISBN 13 : 0309096014
Total Pages : 306 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Ending the War Metaphor by : Institute of Medicine

Download or read book Ending the War Metaphor written by Institute of Medicine and published by National Academies Press. This book was released on 2006-07-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.

Infectious Diseases in Primates

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Publisher : Oxford University Press
ISBN 13 : 0198565844
Total Pages : 397 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Infectious Diseases in Primates by : Charles Nunn

Download or read book Infectious Diseases in Primates written by Charles Nunn and published by Oxford University Press. This book was released on 2006-04-27 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes the following features: The first book to synthesiseand integrate the previously disparate areas of primate socioecology, parasitefunctional categories, host defences, and theoretical models of disease spread.; Organizes hypotheses according to parasite traits such as transmission mode,host specificity and virulence.; Develops a new co-evolutionary framework forinvestigating parasites and primate social evolution at empirical andtheoretical scales.; Ideal graduate seminar course material.

Ecology and Evolution of Infectious Diseases

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Publisher : Oxford University Press
ISBN 13 : 0192507109
Total Pages : 366 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Ecology and Evolution of Infectious Diseases by : Benjamin Roche

Download or read book Ecology and Evolution of Infectious Diseases written by Benjamin Roche and published by Oxford University Press. This book was released on 2018-05-11 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the ecology and evolution of infectious diseases has been studied extensively and new approaches to the study of host-pathogen interactions continue to emerge. At the same time, pathogen control in low-income countries has tended to remain largely informed by classical epidemiology, where the objective is to treat as many people as possible, despite recent research suggesting new opportunities for improved disease control in the context of limited economic resources. The need to integrate the scientific developments in the ecology and evolution of infectious diseases with public health strategy in low-income countries is now more important than ever. This novel text uniquely incorporates the latest research in ecology and evolutionary biology into the discussion of public health issues in low-income countries. It brings together an international team of experts from both universities and health NGOs to provide an up-to-date, authoritative, and challenging review of the ecology and evolution of infectious diseases, focusing on low-income countries for effective public health applications and outcomes. It discusses a range of public health threats including malaria, TB, HIV, measles, Ebola, tuberculosis, influenza and meningitis among others.

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Infectious Diseases of Humans

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Publisher : Oxford University Press
ISBN 13 : 9780198540403
Total Pages : 772 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Infectious Diseases of Humans by : Roy M. Anderson

Download or read book Infectious Diseases of Humans written by Roy M. Anderson and published by Oxford University Press. This book was released on 1991 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with infectious diseases -- viral, bacterial, protozoan and helminth -- in terms of the dynamics of their interaction with host populations. The book combines mathematical models with extensive use of epidemiological and other data. This analytic framework is highly useful for the evaluation of public health strategies aimed at controlling or eradicating particular infections. Such a framework is increasingly important in light of the widespread concern for primary health care programs aimed at such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis, and the advent of AIDS/HIV and other emerging viruses. Throughout the book, the mathematics is used as a tool for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two parts, one dealing with microparasites (viruses, bacteria and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. The book synthesizes previous work in this rapidly growing field (much of which is scattered between the ecological and the medical literature) with a good deal of new material.

The Causes of Evolution

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Publisher : Princeton University Press
ISBN 13 : 9780691024424
Total Pages : 256 pages
Book Rating : 4.0/5 (244 download)

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Book Synopsis The Causes of Evolution by : John Burdon Haldane

Download or read book The Causes of Evolution written by John Burdon Haldane and published by Princeton University Press. This book was released on 1990-10-10 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: J.B.S. Haldane (1892-1964), one of the founders of the science of population genetics, was also one of the greatest practitioners of the art of explaining science to the layperson. Haldane was a superb story-teller, as his essays and his children's books attest. In The Causes of Evolution he not only helped to marry the new science of genetics to the older one of evolutionary theory but also provided an accessible introduction to the genetical basis of evolution by natural selection. Egbert Leigh's new introduction to this classic work places it in the context of the ongoing study of evolution. Describing Haldane's refusal to be confined by a "System" as a "light-hearted" one, Leigh points out that we are now finding that "Haldane's questions are the appropriate next stage in learning how adaptation can evolve. We are now ready to reap the benefit of the fact that Haldane was a free man in the sense that really matters."

The Stockholm Paradigm

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Publisher : University of Chicago Press
ISBN 13 : 022663258X
Total Pages : 423 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis The Stockholm Paradigm by : Daniel R. Brooks

Download or read book The Stockholm Paradigm written by Daniel R. Brooks and published by University of Chicago Press. This book was released on 2019-07-19 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

Genetics and Evolution of Infectious Diseases

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Publisher : Elsevier
ISBN 13 : 0443288194
Total Pages : 0 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc and published by Elsevier. This book was released on 2024-07-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. Takes an integrated approach to infectious diseases Provides the latest developments in the field of infectious diseases Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases Includes updated and revised contributions from leading authorities, along with six new chapters

Infection, Polymorphism and Evolution

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Publisher : Springer Science & Business Media
ISBN 13 : 9400900775
Total Pages : 120 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Infection, Polymorphism and Evolution by : W.D. Hamilton

Download or read book Infection, Polymorphism and Evolution written by W.D. Hamilton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resulting from a Royal Society discussion meeting, this volume presents a short review of the topic of parasite-host co-evolution. Current thinking on evolution in parasites, viruses and other pathogens is discussed.

Primates, Pathogens, and Evolution

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Publisher : Springer
ISBN 13 : 9781461471820
Total Pages : 428 pages
Book Rating : 4.4/5 (718 download)

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Book Synopsis Primates, Pathogens, and Evolution by : Jessica F. Brinkworth

Download or read book Primates, Pathogens, and Evolution written by Jessica F. Brinkworth and published by Springer. This book was released on 2013-08-30 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune systems of human and non-human primates have diverged over time, such that some species differ considerably in their susceptibility, symptoms, and survival of particular infectious diseases. Variation in primate immunity is such that major human pathogens - such as immunodeficiency viruses, herpesviruses and malaria-inducing species of Plasmodium - elicit striking differences in immune response between closely related species and within primate populations. These differences in immunity are the outcome of complex evolutionary processes that include interactions between the host, its pathogens and symbiont/commensal organisms. The success of some pathogens in establishing persistent infections in humans and other primates has been determined not just by the molecular evolution of the pathogen and its interactions with the host, but also by the evolution of primate behavior and ecology, microflora, immune factors and the evolution of other biological systems. To explore how interactions between primates and their pathogens have shaped their mutual molecular evolution, Primates, Pathogens and Evolution brings together research that explores comparative primate immune function, the emergence of major and neglected primate diseases, primate-microorganism molecular interactions, and related topics. This book will be of interest to anyone curious as to why infectious diseases manifest differently in humans and their closest relatives. It will be of particular interest to scholars specializing in human and non-human primate evolution, epidemiology and immunology, and disease ecology. Primates, Pathogens and Evolution offers an overview and discussion of current findings on differences in the molecular mechanics of primate immune response, as well as on pathogen-mediated primate evolution and human and non-human primate health.

Immunology and Evolution of Infectious Disease

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Publisher : Princeton University Press
ISBN 13 : 0691220166
Total Pages : 360 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank

Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2020-10-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive synthesis of parasite variation at the molecular, population, and evolutionary levels, this book is essential reading for students and researchers throughout biology and biomedicine. The author uses an evolutionary perspective to meld the terms and findings of molecular biology, immunology, pathogen biology, and population dynamics. This multidisciplinary approach offers newcomers a readable introduction while giving specialists an invaluable guide to allied subjects. Every aspect of the immune response is presented in the functional context of parasite recognition and defense--an emphasis that gives structure to a tremendous amount of data and brings into sharp focus the great complexity of immunology. The problems that end each chapter set the challenge for future research, and the text includes extensive discussion of HIV, influenza, foot-and-mouth disease, and many other pathogens. This is the only book that treats in an integrated way all factors affecting variation in infectious disease. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For molecular biologists, immunologists, and evolutionary biologists, this book provides new insight into infectious agents, immunity, and the evolution of infectious disease.