In Vivo Determination Of Cerebral Hemodynamics And Bioergetics Using Spin Echo Magnetic Resonance Imaging

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Introduction to Functional Magnetic Resonance Imaging

Author : Richard B. Buxton
Publisher : Cambridge University Press
ISBN 13 : 1139481304
Total Pages : 479 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Introduction to Functional Magnetic Resonance Imaging by : Richard B. Buxton

Download or read book Introduction to Functional Magnetic Resonance Imaging written by Richard B. Buxton and published by Cambridge University Press. This book was released on 2009-08-27 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.

Radiomics and Radiogenomics

Author : Ruijiang Li
Publisher : CRC Press
ISBN 13 : 1351208268
Total Pages : 484 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Radiomics and Radiogenomics by : Ruijiang Li

Download or read book Radiomics and Radiogenomics written by Ruijiang Li and published by CRC Press. This book was released on 2019-07-09 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

Targeted Molecular Imaging in Oncology

Author : E. Edmund Kim
Publisher : Springer Science & Business Media
ISBN 13 : 9780387950280
Total Pages : 322 pages
Book Rating : 4.9/5 (52 download)

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Book Synopsis Targeted Molecular Imaging in Oncology by : E. Edmund Kim

Download or read book Targeted Molecular Imaging in Oncology written by E. Edmund Kim and published by Springer Science & Business Media. This book was released on 2001 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.

Neuroimaging of Sleep and Sleep Disorders

Author : Eric Nofzinger
Publisher : Cambridge University Press
ISBN 13 : 1107018633
Total Pages : 445 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Neuroimaging of Sleep and Sleep Disorders by : Eric Nofzinger

Download or read book Neuroimaging of Sleep and Sleep Disorders written by Eric Nofzinger and published by Cambridge University Press. This book was released on 2013-03-07 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.

Magnetic Resonance in Biology

Author : Jack Sidney Cohen
Publisher :
ISBN 13 : 9780471051763
Total Pages : pages
Book Rating : 4.0/5 (517 download)

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Book Synopsis Magnetic Resonance in Biology by : Jack Sidney Cohen

Download or read book Magnetic Resonance in Biology written by Jack Sidney Cohen and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Traumatic Brain and Spinal Cord Injury

Author : Cristina Morganti-Kossmann
Publisher : Cambridge University Press
ISBN 13 : 1107007437
Total Pages : 361 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Traumatic Brain and Spinal Cord Injury by : Cristina Morganti-Kossmann

Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Brain Disorders in Critical Illness

Author : Robert D. Stevens
Publisher : Cambridge University Press
ISBN 13 : 1107434424
Total Pages : 457 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Brain Disorders in Critical Illness by : Robert D. Stevens

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

The Ischemic Penumbra

Author : Geoffrey A. Donnan
Publisher : CRC Press
ISBN 13 : 1420047353
Total Pages : 354 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Ischemic Penumbra by : Geoffrey A. Donnan

Download or read book The Ischemic Penumbra written by Geoffrey A. Donnan and published by CRC Press. This book was released on 2007-04-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SP

Handbook of Cardiac Anatomy, Physiology, and Devices

Author : Paul A. Iaizzo
Publisher : Springer
ISBN 13 : 331919464X
Total Pages : 806 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Handbook of Cardiac Anatomy, Physiology, and Devices by : Paul A. Iaizzo

Download or read book Handbook of Cardiac Anatomy, Physiology, and Devices written by Paul A. Iaizzo and published by Springer. This book was released on 2015-11-13 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Neural Metabolism In Vivo

Author : In-Young Choi
Publisher : Springer Science & Business Media
ISBN 13 : 1461417880
Total Pages : 1168 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Neural Metabolism In Vivo by : In-Young Choi

Download or read book Neural Metabolism In Vivo written by In-Young Choi and published by Springer Science & Business Media. This book was released on 2012-03-08 with total page 1168 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter

Cardiovascular Magnetic Resonance

Author : Warren J. Manning
Publisher : Elsevier Health Sciences
ISBN 13 : 0323497373
Total Pages : 797 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Cardiovascular Magnetic Resonance by : Warren J. Manning

Download or read book Cardiovascular Magnetic Resonance written by Warren J. Manning and published by Elsevier Health Sciences. This book was released on 2018-04-26 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Provides state-of-the-art coverage of CMR technologies and guidelines, including basic principles, imaging techniques, ischemic heart disease, right ventricular and congenital heart disease, vascular and pericardium conditions, and functional cardiovascular disease. - Includes new chapters on non-cardiac pathology, pacemaker safety, economics of CMR, and guidelines as well as new coverage of myocarditis and its diagnosis and assessment of prognosis by cardiovascular magnetic resonance, and the use of PET/CMR imaging of the heart, especially in sarcoidosis. - Features more than 1,100 high-quality images representing today's CMR imaging. - Covers T1, T2 and ECV mapping, as well as T2* imaging in iron overload, which has been shown to save lives in patients with thalassaemia major - Discusses the cost-effectiveness of CMR. - Provides state-of-the-art coverage of CMR technologies and guidelines, including basic principles, imaging techniques, ischemic heart disease, right ventricular and congenital heart disease, vascular and pericardium conditions, and functional cardiovascular disease. - Includes new chapters on non-cardiac pathology, pacemaker safety, economics of CMR, and guidelines as well as new coverage of myocarditis and its diagnosis and assessment of prognosis by cardiovascular magnetic resonance, and the use of PET/CMR imaging of the heart, especially in sarcoidosis. - Features more than 1,100 high-quality images representing today's CMR imaging. - Covers T1, T2 and ECV mapping, as well as T2* imaging in iron overload, which has been shown to save lives in patients with thalassaemia major. - Discusses the cost-effectiveness of CMR. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Applied Cardiovascular Physiology

Author : Michael Pinsky
Publisher : Springer Science & Business Media
ISBN 13 : 3642606962
Total Pages : 405 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Applied Cardiovascular Physiology by : Michael Pinsky

Download or read book Applied Cardiovascular Physiology written by Michael Pinsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios.

Evidence-Based Critical Care

Author : Paul Ellis Marik
Publisher : Springer
ISBN 13 : 3319110209
Total Pages : 836 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Evidence-Based Critical Care by : Paul Ellis Marik

Download or read book Evidence-Based Critical Care written by Paul Ellis Marik and published by Springer. This book was released on 2014-12-08 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new paradigm in critical care medicine, cardiac output monitoring, surgical optimization, vital signs, and arterial blood gas analysis. The book maintains the author’s trademark humor and engaging writing style and is suitable for a broad and diverse audience of medical students, residents, fellows, physicians, nurses, and respiratory therapists who seek the latest and best evidence in critical care. From reviews of previous editions: “This is an excellent introduction to the concept of evidence-based medicine...The writing is clear, logical, and highly organized, which makes for fast and enjoyable reading. I believe this book will get daily use in most intensive care units, by a wide range of readers.” –Respiratory Care “This is one of the most comprehensive handbooks on critical care medicine with a strong emphasis on evidence base...Overall, this book should be useful for junior doctors or intensive care trainees who are starting their term in an intensive care unit.” –Anaesthesia and Intensive Care

Laboratory Animal Anaesthesia

Author : Paul Flecknell
Publisher : Academic Press
ISBN 13 : 0080918999
Total Pages : 325 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Laboratory Animal Anaesthesia by : Paul Flecknell

Download or read book Laboratory Animal Anaesthesia written by Paul Flecknell and published by Academic Press. This book was released on 2009-04-09 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals' body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.• New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography• Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals• Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area• Provides rapid, easily accessed information using tabulated summaries• Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely• Provides sufficient depth for the more experienced anesthetist moving to this field

Thyroid, Obesity and Metabolism

Author : Livio Luzi
Publisher : Springer Nature
ISBN 13 : 3030802671
Total Pages : 268 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Thyroid, Obesity and Metabolism by : Livio Luzi

Download or read book Thyroid, Obesity and Metabolism written by Livio Luzi and published by Springer Nature. This book was released on 2021-08-27 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide readers with up-to-date information on thyroid diseases, obesity and metabolic syndrome. The innovative element is the presentation and exploration of possible connections linking thyroid diseases and metabolism dysfunction. Starting from the classification and diagnosis of thyroid diseases, obesity and metabolic syndrome, techniques to study and treat each of the mentioned diseases are given in an easy-to-use way. This volume will be a useful tool for endocrinologists, diabetologists, dieticians, and any professionals involved in the treatment of thyroid diseases.

Critical Care Nephrology and Renal Replacement Therapy in Children

Author : Akash Deep
Publisher : Springer
ISBN 13 : 3319902814
Total Pages : 456 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Critical Care Nephrology and Renal Replacement Therapy in Children by : Akash Deep

Download or read book Critical Care Nephrology and Renal Replacement Therapy in Children written by Akash Deep and published by Springer. This book was released on 2018-08-17 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents an invaluable resource for professionals for the diagnosis and treatment of acute kidney injury (AKI) in children and how to select and deliver the appropriate form of renal replacement therapy (RRT). Experts from all over the globe have come together to share their wide experience in the field of Critical Care Nephrology in children. Paediatric critical care nephrology is a complex and highly specialised field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time to address all the topics in the field of critical care nephrology in children in a unique book which is the first of its kind. This book covers the basics as well as advances in the field of Critical Care Nephrology. Each chapter is dedicated to practical aspects of a particular topic elucidating various management decision points. Each chapter is also accompanied with algorithms, figures and protocols in tabulated format. Information on how to manage specific conditions are contextualized with relevant background anatomy, physiology and biochemistry and practical examples. At the end of the chapter, there are key learning points. Paediatricians, nephrologists and paediatric intensivists, as well as paediatric critical care and nephrology nurses in all countries will find this book an invaluable reference text.

Muscles as Molecular and Metabolic Machines

Author : Peter W. Hochachka
Publisher : CRC Press
ISBN 13 : 1000013111
Total Pages : 224 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Muscles as Molecular and Metabolic Machines by : Peter W. Hochachka

Download or read book Muscles as Molecular and Metabolic Machines written by Peter W. Hochachka and published by CRC Press. This book was released on 2019-06-04 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1994, this book explores the paradigm of muscles as molecular and metabolic machines in which all structures and functions are exquisitely integrated and matched to each other. The analysis begins with a standard reductionist approach-reviewing the integrated machine parts. The key working components of the complete muscle machine are proteins (soluble, organelle, or membrane localized), and a conservative count indicates that today more than 100 such machine parts are known, essentially all occurring as cell specific isoforms. Random assortment of these machine parts or protein isoforms could generate an astronomical number of "muscle machines" and an equally enormous number of muscle fiber types. The question is, why aren't such large numbers ever seen? To attack this problem, the reductionist approach is complemented with an integrationist/adaptational one. Evidence is presented that the more highly specialized the muscle type, the further one moves from the above extreme; in the most highly specialized muscles, typically only one fiber type is found. It is argued that instead of random assortment of isoforms or machine parts, only specific and often unique combinations can work in appropriate fashion. A few established examples of this fundamental principle are reviewed, but emphasis is placed on the fact that we know dreadfully little about why this is so and what kinds of further studies are needed. The issue of why the very large numbers of fiber types theoretically possible are never even approximately realized has never before been addressed. Indeed, it is rarely recognized. Muscles as Molecular and Metabolic Machines is the first work of its kind on the subject.