Implementation Of Automated Visual Inspection Machines In Biopharmaceutical Industry

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Implementation of Automated Visual Inspection Machines in Biopharmaceutical Industry

Author : Prosper Munaishe Nyovanie
Publisher :
ISBN 13 :
Total Pages : 74 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis Implementation of Automated Visual Inspection Machines in Biopharmaceutical Industry by : Prosper Munaishe Nyovanie

Download or read book Implementation of Automated Visual Inspection Machines in Biopharmaceutical Industry written by Prosper Munaishe Nyovanie and published by . This book was released on 2019 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, manual visual inspection is the gold standard for the required visual inspection of particulate matter in parenteral medicines. Automated visual inspection machines offer an opportunity for Amgen to improve efficiency, rate and consistency, while reducing its equipment footprint. However, the implementation of automated visual inspection poses challenges that need to be resolved. This thesis identified and developed solutions to three execution pain points: (1) low detection rates of dense particles in products; (2) misuse of automated inspection machines for product impact testing; and (3) ambiguous understanding of cost drivers when selecting an inspection method. The pain points mentioned above were addressed separately. First, experiments with modified plunger surfaces were conducted to determine their effectiveness at agitating dense particles into solution where the particles could then be easily detected. Second, embedded sensors were identified as the sensor of choice to measure the mechanical stress history of products passing through an automated visual inspection machine. Experiments were designed to test the effectiveness of accelerometers to replace the limited range of gyroscopes' rotational velocity measurements. Third, a cost benefit analysis model was created that used discounted cash flows to calculate the net present cost of selecting automated visual inspection or manual visual inspection. The results of these three work streams were promising. First, the experiments with modified plunger surfaces showed up to a 97% success rate of agitating particles into solution compared to an 1% success rate for the original plunger design. Second, experiments on accelerometers in embedded sensors showed that the accelerometers could measure centripetal acceleration that related to rotational velocity. A linear regression model was developed to relate accelerometer readings to rotational velocity within an accuracy of 50 RPM. Lastly, the cost benefit analysis model confirmed expected drivers regarding the favorability of different inspection methods. The model also showed that automated visual inspection is the cheaper method of inspection, even with conservative estimates of cost of capital and false eject rates. A follow-up effort is necessary to achieve a more streamlined implementation of automated visual inspection machines throughout Amgen's manufacturing network.

Machine Vision

Author : Jürgen Beyerer
Publisher : Springer
ISBN 13 : 3662477947
Total Pages : 802 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Machine Vision by : Jürgen Beyerer

Download or read book Machine Vision written by Jürgen Beyerer and published by Springer. This book was released on 2015-10-01 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book offers a thorough introduction to machine vision. It is organized in two parts. The first part covers the image acquisition, which is the crucial component of most automated visual inspection systems. All important methods are described in great detail and are presented with a reasoned structure. The second part deals with the modeling and processing of image signals and pays particular regard to methods, which are relevant for automated visual inspection.

Intelligent Visual Inspection

Author : R. Rosandich
Publisher : Springer Science & Business Media
ISBN 13 : 1461312019
Total Pages : 311 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Intelligent Visual Inspection by : R. Rosandich

Download or read book Intelligent Visual Inspection written by R. Rosandich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of research is being done in the areas of artificial vision and neural networks. Although much of this research has been theoretical in nature, many of the techniques developed through these efforts are now mature enough for use in practical applications. Automated Visual Inspection Using Artificial Neural Networks explains the application of recently emerging technology in the areas of artificial vision and neural networks to automated visual inspection. The information is organised in a clear, informative manner, bridging the gap between theoretical research and practical application. Significantly this book includes: * broad coverage of all aspects of the automated visual inspection problem, * details of the HAVENET neural network and the CAMERA vision model, and * detailed descriptions of practical applications of intelligent visual inspection.

Machine Vision for the Inspection of Natural Products

Author : Mark Graves
Publisher : Springer Science & Business Media
ISBN 13 : 1852338539
Total Pages : 472 pages
Book Rating : 4.8/5 (523 download)

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Book Synopsis Machine Vision for the Inspection of Natural Products by : Mark Graves

Download or read book Machine Vision for the Inspection of Natural Products written by Mark Graves and published by Springer Science & Business Media. This book was released on 2006-05-18 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine vision technology has revolutionised the process of automated inspection in manufacturing. The specialist techniques required for inspection of natural products, such as food, leather, textiles and stone is still a challenging area of research. Topological variations make image processing algorithm development, system integration and mechanical handling issues much more complex. The practical issues of making machine vision systems operate robustly in often hostile environments together with the latest technological advancements are reviewed in this volume. Features: - Case studies based on real-world problems to demonstrate the practical application of machine vision systems. - In-depth description of system components including image processing, illumination, real-time hardware, mechanical handling, sensing and on-line testing. - Systems-level integration of constituent technologies for bespoke applications across a variety of industries. - A diverse range of example applications that a system may be required to handle from live fish to ceramic tiles. Machine Vision for the Inspection of Natural Products will be a valuable resource for researchers developing innovative machine vision systems in collaboration with food technology, textile and agriculture sectors. It will also appeal to practising engineers and managers in industries where the application of machine vision can enhance product safety and process efficiency.

Smart Inspection Systems

Author : Duc T. Pham
Publisher : Elsevier
ISBN 13 : 0080541275
Total Pages : 236 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Smart Inspection Systems by : Duc T. Pham

Download or read book Smart Inspection Systems written by Duc T. Pham and published by Elsevier. This book was released on 2002-12-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Inspection Systems: Techniques and Applications of Intelligent Vision will enable engineers to understand the various stages of automated visual inspection (AVI) and how artificial intelligence can be incorporated into each stage to create "smart" inspection systems. The book contains many examples that illustrate and explain the application of conventional and artificial intelligence techniques in AVI. The text covers the whole AVI process, from illumination, image enhancement, segmentation and feature extraction, through to classification, and includes case studies of implemented AVI systems as well as reviews of commercially available inspection systems. Each chapter concludes with exercises. This book will be of interest to users and developers of commercial industrial inspection systems as well as researchers in the fields of machine vision, artificial intelligence and advanced manufacturing engineering.

Implementation of Automatic Inspection System

Author : Yugank Chawla
Publisher :
ISBN 13 :
Total Pages : 80 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Implementation of Automatic Inspection System by : Yugank Chawla

Download or read book Implementation of Automatic Inspection System written by Yugank Chawla and published by . This book was released on 2014 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inspection is the formal examination of a product manufactured by any manufacturing process. Inspection process is critical to all the industries as it ensures that a good quality product reach at the end customers. In order to ensure minimum variation in the quality of inspection of a product, industries rely on advanced equipment or gauge to measure the quality parameters of the product. The accuracy of inspection depends a lot on the method and equipments used to inspect a product. However, at AvCarb material solutions, a product called pyrolytic graphite sheet (PGS) is manufactured and at present the types of defects that occur during their manufacturing process can only be identified visually. The problem with using human senses as a tool to perform an inspection is that the accuracy and speed of the inspection vary from person to person based on their experience, their state of mind and other human factors. Automating a visual inspection system ensures minimum variation in the accuracy and speed of an inspection process. This thesis proposes the use of the automatic vision system to perform visual inspection of PGS. The document presents how some software tools can be used to identify and quantify the defects generated on PGS and gives a comparison of the accuracy of identifying a defect through the automatic vision system and accuracy achieved through human inspection.

Machine Vision Inspection Systems

Author : Muthukumaran Malarvel
Publisher : John Wiley & Sons
ISBN 13 : 1119681960
Total Pages : 256 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Machine Vision Inspection Systems by : Muthukumaran Malarvel

Download or read book Machine Vision Inspection Systems written by Muthukumaran Malarvel and published by John Wiley & Sons. This book was released on 2020-05-21 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book brings together leading researchers, academic scientists and research scholars to put forward and share their experiences and research results on all aspects of an inspection system for detection analysis for various machine vision applications. It also provides a premier interdisciplinary platform to present and discuss the most recent innovations, trends, methodology, applications, and concerns as well as practical challenges encountered and solutions adopted in the inspection system in terms of image processing and analytics of machine vision for real and industrial application. Machine vision inspection systems (MVIS) utilized all industrial and non-industrial applications where the execution of their utilities based on the acquisition and processing of images. MVIS can be applicable in industry, governmental, defense, aerospace, remote sensing, medical, and academic/education applications but constraints are different. MVIS entails acceptable accuracy, high reliability, high robustness, and low cost. Image processing is a well-defined transformation between human vision and image digitization, and their techniques are the foremost way to experiment in the MVIS. The digital image technique furnishes improved pictorial information by processing the image data through machine vision perception. Digital image processing has widely been used in MVIS applications and it can be employed to a wide diversity of problems particularly in Non-Destructive testing (NDT), presence/absence detection, defect/fault detection (weld, textile, tiles, wood, etc.,), automated vision test & measurement, pattern matching, optical character recognition & verification (OCR/OCV), barcode reading and traceability, medical diagnosis, weather forecasting, face recognition, defence and space research, etc. This edited book is designed to address various aspects of recent methodologies, concepts and research plan out to the readers for giving more depth insights for perusing research on machine vision using image processing techniques.

Automated Inspection and Quality Assurance

Author : Stanley L. Robinson
Publisher : CRC Press
ISBN 13 : 1351465082
Total Pages : 273 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Automated Inspection and Quality Assurance by : Stanley L. Robinson

Download or read book Automated Inspection and Quality Assurance written by Stanley L. Robinson and published by CRC Press. This book was released on 2017-11-22 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers new concepts for gaging, inspection, machines vision and robotic testing Includes guidelines for installing complex electronic and computerized systems Presents a directory of commercially available computer software, as well as distributors' names and addresses

Automated Visual Inspection

Author : Bruce G. Batchelor
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.:/5 (41 download)

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Book Synopsis Automated Visual Inspection by : Bruce G. Batchelor

Download or read book Automated Visual Inspection written by Bruce G. Batchelor and published by Elsevier Science & Technology. This book was released on 1985 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Industrial Image Processing

Author : Christian Demant
Publisher : Springer Science & Business Media
ISBN 13 : 3642339050
Total Pages : 378 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Industrial Image Processing by : Christian Demant

Download or read book Industrial Image Processing written by Christian Demant and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical introduction focuses on how to design integrated solutions for industrial vision tasks from individual algorithms. The book is now available in a revised second edition that takes into account the current technological developments, including camera technology and color imaging processing. It gives a hands-on guide for setting up automated visual inspection systems using real-world examples and the NeuroCheck® standard software that has proven industrial strength integrated in thousands of applications in real-world production lines. Based on many years of experience in industry, the authors explain all the essential details encountered in the creation of vision system installations. With example material and a demo version of the software found on "extras.springer.com" readers can work their way through the described inspection tasks and carry out their own experiments.

Integrated Imaging and Vision Techniques for Industrial Inspection

Author : Zheng Liu
Publisher : Springer
ISBN 13 : 1447167414
Total Pages : 541 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Integrated Imaging and Vision Techniques for Industrial Inspection by : Zheng Liu

Download or read book Integrated Imaging and Vision Techniques for Industrial Inspection written by Zheng Liu and published by Springer. This book was released on 2015-09-24 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pioneering text/reference presents a detailed focus on the use of machine vision techniques in industrial inspection applications. An internationally renowned selection of experts provide insights on a range of inspection tasks, drawn from their cutting-edge work in academia and industry, covering practical issues of vision system integration for real-world applications. Topics and features: presents a comprehensive review of state-of-the-art hardware and software tools for machine vision, and the evolution of algorithms for industrial inspection; includes in-depth descriptions of advanced inspection methodologies and machine vision technologies for specific needs; discusses the latest developments and future trends in imaging and vision techniques for industrial inspection tasks; provides a focus on imaging and vision system integration, implementation, and optimization; describes the pitfalls and barriers to developing successful inspection systems for smooth and efficient manufacturing process.

Machine Vision Inspection Systems, Machine Learning-Based Approaches

Author : Muthukumaran Malarvel
Publisher : John Wiley & Sons
ISBN 13 : 1119786118
Total Pages : 352 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Machine Vision Inspection Systems, Machine Learning-Based Approaches by : Muthukumaran Malarvel

Download or read book Machine Vision Inspection Systems, Machine Learning-Based Approaches written by Muthukumaran Malarvel and published by John Wiley & Sons. This book was released on 2021-01-15 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Vision Inspection Systems (MVIS) is a multidisciplinary research field that emphasizes image processing, machine vision and, pattern recognition for industrial applications. Inspection techniques are generally used in destructive and non-destructive evaluation industry. Now a day's the current research on machine inspection gained more popularity among various researchers, because the manual assessment of the inspection may fail and turn into false assessment due to a large number of examining while inspection process. This volume 2 covers machine learning-based approaches in MVIS applications and it can be employed to a wide diversity of problems particularly in Non-Destructive testing (NDT), presence/absence detection, defect/fault detection (weld, textile, tiles, wood, etc.), automated vision test & measurement, pattern matching, optical character recognition & verification (OCR/OCV), natural language processing, medical diagnosis, etc. This edited book is designed to address various aspects of recent methodologies, concepts, and research plan out to the readers for giving more depth insights for perusing research on machine vision using machine learning-based approaches.

PAT Applied in Biopharmaceutical Process Development And Manufacturing

Author : Cenk Undey
Publisher : CRC Press
ISBN 13 : 1439829462
Total Pages : 327 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis PAT Applied in Biopharmaceutical Process Development And Manufacturing by : Cenk Undey

Download or read book PAT Applied in Biopharmaceutical Process Development And Manufacturing written by Cenk Undey and published by CRC Press. This book was released on 2011-12-07 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH). Given the rapid growth in the biopharmaceutical area and the comp

Machine Vision for the Inspection of Natural Products

Author : Mark Graves
Publisher : Springer
ISBN 13 : 9781447139188
Total Pages : 471 pages
Book Rating : 4.1/5 (391 download)

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Book Synopsis Machine Vision for the Inspection of Natural Products by : Mark Graves

Download or read book Machine Vision for the Inspection of Natural Products written by Mark Graves and published by Springer. This book was released on 2013-10-03 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine vision technology has revolutionised the process of automated inspection in manufacturing. The specialist techniques required for inspection of natural products, such as food, leather, textiles and stone is still a challenging area of research. Topological variations make image processing algorithm development, system integration and mechanical handling issues much more complex. The practical issues of making machine vision systems operate robustly in often hostile environments together with the latest technological advancements are reviewed in this volume. Features: - Case studies based on real-world problems to demonstrate the practical application of machine vision systems. - In-depth description of system components including image processing, illumination, real-time hardware, mechanical handling, sensing and on-line testing. - Systems-level integration of constituent technologies for bespoke applications across a variety of industries. - A diverse range of example applications that a system may be required to handle from live fish to ceramic tiles. Machine Vision for the Inspection of Natural Products will be a valuable resource for researchers developing innovative machine vision systems in collaboration with food technology, textile and agriculture sectors. It will also appeal to practising engineers and managers in industries where the application of machine vision can enhance product safety and process efficiency.

Evaluating Future Biopharmaceutical Inspection Needs, Infrastructure Capability Gaps, and Technology Development Strategies

Author : Marnix English Hollander
Publisher :
ISBN 13 :
Total Pages : 70 pages
Book Rating : 4.:/5 (815 download)

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Book Synopsis Evaluating Future Biopharmaceutical Inspection Needs, Infrastructure Capability Gaps, and Technology Development Strategies by : Marnix English Hollander

Download or read book Evaluating Future Biopharmaceutical Inspection Needs, Infrastructure Capability Gaps, and Technology Development Strategies written by Marnix English Hollander and published by . This book was released on 2012 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biotechnology industry is undergoing a paradigm shift in the properties of the manufactured drug product. As therapeutic protein formulations change from agonist to antagonist methods of action, the concentration of proteins in each dose increased by orders of magnitude, and with it, the challenge of producing and inspecting the product. Current inspection technologies meet the requirements to properly inspect the existing drug product portfolio, but as new pipeline drugs enter commercial manufacturing, inspection will become a pressing issue from operational efficiency, compliance, and quality standpoints. It is known that the properties of some of these pipeline products render them "uninspectable" by currently installed Automatic Visual Inspection Machines (AVIMs) but the scale and scope of the challenge is not well defined currently. The process and approach outlined in this research focuses on distilling large datasets of future product forecasts together with product attributes and infrastructure capability to generate a quantitative understanding of the future challenge. Through this research, product attributes critical to inspection such as viscosity, presentation, and protein aggregation, are identified for each commercial and pipeline drug product. These attributes are paired with production forecasts to generate attribute focused inspection requirements through 2020, which are then mapped against current capabilities. Gaps identified between requirements and current infrastructure capabilities are determined and the scale quantified. These capability gaps are then segmented by potential solutions, complexity of solutions, and cost of inaction in order to give Amgen the best foresight into future decisions and investments. Based on the gaps identified and near term engineering challenges, several solutions are developed, proposed, and tested throughout the internship. These include the use of Surface Acoustic Waves (SAW) to agitate heavy particles into suspension through acoustic streaming, enhanced lighting and imaging techniques to better identify particles, and segmented machine vision algorithms. These approaches are part of a larger portfolio of technical solutions which must be developed to address future product attributes which render current inspection processes ineffective.

Machine Vision for Robotics and Automated Inspection

Author : Richard K. Miller
Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Machine Vision for Robotics and Automated Inspection by : Richard K. Miller

Download or read book Machine Vision for Robotics and Automated Inspection written by Richard K. Miller and published by . This book was released on 1983 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sterile Drug Products

Author : Michael J. Akers
Publisher : CRC Press
ISBN 13 : 1420020560
Total Pages : 517 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Sterile Drug Products by : Michael J. Akers

Download or read book Sterile Drug Products written by Michael J. Akers and published by CRC Press. This book was released on 2016-04-19 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sterile Drug Products: Formulation, Packaging, Manufacturing, and Quality teaches the basic principles of the development and manufacture of high quality sterile dosage forms. The author has 38 years of experience in the development and manufacture of sterile dosage forms including solutions, suspensions, ophthalmics and freeze dried products. This