Impact Of Engineered Nanomaterials In Genomics And Epigenomics

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Impact of Engineered Nanomaterials in Genomics and Epigenomics

Author : Saura C. Sahu
Publisher : John Wiley & Sons
ISBN 13 : 1119896223
Total Pages : 453 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Impact of Engineered Nanomaterials in Genomics and Epigenomics by : Saura C. Sahu

Download or read book Impact of Engineered Nanomaterials in Genomics and Epigenomics written by Saura C. Sahu and published by John Wiley & Sons. This book was released on 2023-08-14 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impact of Engineered Nanomaterials in Genomics and Epigenomics Overview of current research and technologies in nanomaterial science as applied to omics science at the single cell level Impact of Engineered Nanomaterials in Genomics and Epigenomics is a comprehensive and authoritative compilation of the genetic processes and instructions that specifically direct individual genes to turn on or off, focusing on the developing technologies of engineering nanomaterials and their role in cell engineering which have become important research tools for pharmaceutical, biological, medical, and toxicological studies. Combining state-of-the art information on the impact of engineered nanomaterials in genomics and epigenomics, from a range of internationally recognized investigators from around the world, this edited volume offers unique insights into the current trends and future directions of research in this scientific field. Impact of Engineered Nanomaterials in Genomics and Epigenomics includes detailed information on sample topics such as: Impact of engineered nanomaterials in genomics and epigenomics, including adverse impact on glucose energy metabolism Toxicogenomics, toxicoepigenomics, genotoxicity and epigenotoxicity, and mechanisms of toxicogenomics and toxicoepigenomics Adverse effects of engineered nanomaterials on human environment and metabolomics pathways leading to ecological toxicity Meta-analysis methods to identify genomic toxicity mechanisms of engineered nanomaterials and biological effects of engineered nanomaterial exposure Artificial intelligence and machine learning of single-cell transcriptomics of engineered nanoparticles and trends in plant nano-interaction to mitigate abiotic stresses This comprehensive work is a valuable and excellent source of authoritative and up-to-date information for advanced students and researchers, toxicologists, the drug industry, risk assessors and regulators in academia, industry, and government, as well as for clinical scientists working in hospital and clinical environments.

Environmental Nanotoxicology

Author : Patrick Omoregie Isibor
Publisher : Springer Nature
ISBN 13 : 3031541545
Total Pages : 358 pages
Book Rating : 4.0/5 (315 download)

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Book Synopsis Environmental Nanotoxicology by : Patrick Omoregie Isibor

Download or read book Environmental Nanotoxicology written by Patrick Omoregie Isibor and published by Springer Nature. This book was released on 2024 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Nanotoxicology: Combatting the Minute Contaminants is a comprehensive guide to the rapidly evolving field of nanotoxicology and its implications for environmental health and safety. This book results from the collaborative efforts of leading experts and researchers from diverse disciplines, aiming to thoroughly understand the interactions between nanomaterials and the environment and their potential impacts on the delicate balance of our ecosystems. Nanotechnology has witnessed remarkable innovations leading to the development of nanomaterials with novel properties and applications across various industries. Alongside these innovations, concerns have arisen about the potential risks that nanomaterials may pose to the environment and living organisms. This book addresses these concerns by comprehensively exploring the field's key concepts, principles, and methodologies. It includes case studies and offers insights into developing appropriate regulatory frameworks and guidelines for the responsible use and disposal of nanomaterials. The book is a valuable resource for researchers and professionals working in nanotoxicology on the complex challenges posed by the intersection of nanomaterials and the environment. It is also an essential reference for students studying environmental science, toxicology, and nanotechnology. Addresses risk assessment and management in nanotoxicology; Explores the life cycle assessment of nanoparticles; Sheds light on emerging technologies and future directions in environmental nanotoxicology. .

Adverse Effects of Engineered Nanomaterials

Author : Bengt Fadeel
Publisher : Academic Press
ISBN 13 : 0123869404
Total Pages : 367 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Adverse Effects of Engineered Nanomaterials by : Bengt Fadeel

Download or read book Adverse Effects of Engineered Nanomaterials written by Bengt Fadeel and published by Academic Press. This book was released on 2012-01-27 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety.

Omics Technologies and Bio-engineering

Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128047496
Total Pages : 645 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Omics Technologies and Bio-engineering by : Debmalya Barh

Download or read book Omics Technologies and Bio-engineering written by Debmalya Barh and published by Academic Press. This book was released on 2017-12-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. - Covers various aspects of biotechnology and bio-engineering using omics technologies - Focuses on the latest developments in the field, including biofuel technologies - Provides key insights into omics approaches in personalized and precision medicine - Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

RNA Nanotechnology

Author : Bin Wang
Publisher : CRC Press
ISBN 13 : 9814411647
Total Pages : 468 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis RNA Nanotechnology by : Bin Wang

Download or read book RNA Nanotechnology written by Bin Wang and published by CRC Press. This book was released on 2014-04-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades there has been incredible growth in "bionano"-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.

Exposure to Engineered Nanomaterials in the Environment

Author : Nelson Marmiroli
Publisher : Elsevier
ISBN 13 : 0128148365
Total Pages : 363 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Exposure to Engineered Nanomaterials in the Environment by : Nelson Marmiroli

Download or read book Exposure to Engineered Nanomaterials in the Environment written by Nelson Marmiroli and published by Elsevier. This book was released on 2019-05-28 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to Engineered Nanomaterials in the Environment provide a new, holistic framework for testing and evaluating the potential benefits and risks of engineered nanomaterials (ENMs), including their potential socioeconomic impacts, ethical issues and consumers' expectations and fears. The book covers nanomaterial presence in various environments, agroecosystems and other areas within the human sphere of actions. The book includes sections on (i) Chemical, physical and biological properties, (ii) Presence and diffusion of ENMs in human environments, agriculture, food and drug products, (iii) ENMs as a pillar in biological and medical research, and (iv) Social and regulatory issues emerging from years of application. The book is designed to increase awareness to key end-users and stakeholders, including food producers and processors, industry, representatives of society and consumers, and those looking to implement an accurate and effective risk analysis procedure that promotes the sustainable use of nanotechnology. - Assesses both the positive and negative impacts of engineered nanomaterials in the environment - Shows how engineered nanomaterials are used in agricultural environments, food products, drugs and cosmetics - Discusses the unique properties of a range of engineered nanomaterials that lead to their environmental effects

Test No. 478: Rodent Dominant Lethal Test

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264243119
Total Pages : 15 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis Test No. 478: Rodent Dominant Lethal Test by : OECD

Download or read book Test No. 478: Rodent Dominant Lethal Test written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In this test, the used genetic endpoints measure mutation at hypoxanthine-guanine phosphoribosyl transferase (HPRT), and at a transgene of xanthineguanine phosphoribosyl ...

The Maturing Nanotechnology Market

Author : BCC Research
Publisher :
ISBN 13 : 9781622963850
Total Pages : pages
Book Rating : 4.9/5 (638 download)

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Book Synopsis The Maturing Nanotechnology Market by : BCC Research

Download or read book The Maturing Nanotechnology Market written by BCC Research and published by . This book was released on 2016-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicity of Nanomaterials

Author : Suresh C. Pillai
Publisher :
ISBN 13 : 9780429265471
Total Pages : 0 pages
Book Rating : 4.2/5 (654 download)

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Book Synopsis Toxicity of Nanomaterials by : Suresh C. Pillai

Download or read book Toxicity of Nanomaterials written by Suresh C. Pillai and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Choice Recommended Title, April 2020 This comprehensive book, edited by two leading experts in nanotechnology and bioengineering with contributions from a global team of specialists, provides a detailed overview of the environmental and health impacts associated with the toxicology of nanomaterials. Special attention is given to nanomaterial toxicity during synthesis, production and application, and chapters throughout are focused on key areas that are important for future research and development of nanomaterials. This book will be of interest to advanced students studying biomedical engineering and materials science, PhD researchers, post-docs and academics working in the area of nanotechnology, medicine, manufacturing and regulatory bodies. Features: Collates and critically evaluates various aspects of the toxicology of nanomaterials in one comprehensive text Discusses the various effects of nanocrystals including the morphologies on cytotoxicity, in addition to the environmental and cytotoxicity risks of graphene and 2D nanomaterials Explores practical methods of detection and quantification, with applications in the environmental and healthcare fields

Epigenetics and Metabolomics

Author : Paban K. Agrawala
Publisher : Elsevier
ISBN 13 : 0323856535
Total Pages : 478 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Epigenetics and Metabolomics by : Paban K. Agrawala

Download or read book Epigenetics and Metabolomics written by Paban K. Agrawala and published by Elsevier. This book was released on 2021-08-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. - Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research - Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others - Provides guidance in epigenomics and metabolomic research methodology

Epigenetics of Chronic Pain

Author :
Publisher : Academic Press
ISBN 13 : 0128140712
Total Pages : 250 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Epigenetics of Chronic Pain by :

Download or read book Epigenetics of Chronic Pain written by and published by Academic Press. This book was released on 2018-10-29 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined, with data derived from epigenetic studies on peripheral and central mechanisms of pain sensitivity in animal models and clinical cases studies. The studies and case examples cited highlight therapeutic pathways of significance and next steps for researchers to develop epigenetic-based treatments for chronic pain. In recent years, epigenetic regulation of gene expression has been shown to play a central role in managing human pain sensitivity. Findings show that expression of many genes critical to increases or decreases in pain sensitivity are indeed regulated by DNA methylation and its enzymes, histone-involved chromatin remodeling, and noncoding RNAs, mainly microRNAs. - Compiles all known information on epigenetic regulation of chronic pain in one volume - Covers the basic functionality of epigenetic mechanisms involved in pain management, applications of recent research in understanding different types of chronic pain, and pathways for developing therapeutics - Leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss epigenetics in inflammatory, neuropathic, visceral, and other pain models in-depth - Enables clinicians, researchers, and pharmacologists to better understand and treat chronic pain

Advances in Bioinformatics

Author : Vijai Singh
Publisher : Springer Nature
ISBN 13 : 9819984017
Total Pages : 365 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Advances in Bioinformatics by : Vijai Singh

Download or read book Advances in Bioinformatics written by Vijai Singh and published by Springer Nature. This book was released on with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Bioengineering

Author : Renu Vyas
Publisher : Springer Nature
ISBN 13 : 9811520631
Total Pages : 229 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Advances in Bioengineering by : Renu Vyas

Download or read book Advances in Bioengineering written by Renu Vyas and published by Springer Nature. This book was released on 2020-05-11 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a single source of information on three major bioengineering areas: engineering at the cellular and molecular level; biomedical devices / instrument engineering; and data engineering. It explores the latest strategies that are essential to advancing our understanding of the mechanisms of human diseases, the development of new enzyme-based technologies, diagnostics, prosthetics, high-performance computing platforms for managing huge amounts of biological data, and the use of deep learning methods to create predictive models. The book also highlights the growing importance of integrating chemistry into life sciences research, most notably concerning the development and evaluation of nanomaterials and nanoparticles and their interactions with biological material. The underlying interdisciplinary theme of bioengineering is addressed in a range of multifaceted applications and worked out examples provided in each chapter.

Contemporary Oral Oncology

Author : Moni Abraham Kuriakose
Publisher : Springer
ISBN 13 : 3319149113
Total Pages : 541 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Contemporary Oral Oncology by : Moni Abraham Kuriakose

Download or read book Contemporary Oral Oncology written by Moni Abraham Kuriakose and published by Springer. This book was released on 2016-12-08 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of four volumes that together offer an authoritative, in-depth reference guide covering all aspects of the management of oral cancer from a multidisciplinary perspective and on the basis of a strong scientific foundation. This volume, on tumor biology, epidemiology, etiology, emerging role of cancer stem cells and prevention of oral cancer, opens by discussing oral carcinogenesis in general and the role of particular carcinogens and human papillomavirus. Global epidemiology and changes in disease prevalence are then addressed. Up-to-date information is provided on emerging cancer biomarkers, and the biologic basis of personalized therapy is explained. Histopathological features of malignant and premalignant neoplasms and their relevance to management are described. Further chapters focus on the current status of chemoprevention, the management of oral submucous fibrosis, and the value of various diagnostic adjuncts. The volume concludes by critically evaluating the efficacy of oral screening methods. Volume 1: Biology, Epidemiology, Etiology, and Prevention Volume 2: Diagnosis and Management Volume 3: Oral and Maxillofacial Reconstructive Surgery Volume 4: Rehabilitation and Supportive Care

Epigenetics Protocols

Author : Trygve O. Tollefsbol
Publisher : Humana Press
ISBN 13 : 9781588293367
Total Pages : 304 pages
Book Rating : 4.2/5 (933 download)

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Book Synopsis Epigenetics Protocols by : Trygve O. Tollefsbol

Download or read book Epigenetics Protocols written by Trygve O. Tollefsbol and published by Humana Press. This book was released on 2004-07-23 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of epigenetics has grown exponentially in the past decade, and a steady flow of exciting discoveries in this area has served to move it to the forefront of molecular biology. Although epigenetics may previously have been considered a peripheral science, recent advances have shown considerable progress in unraveling the many mysteries of nontraditional genetic processes. Given the fast pace of epigenetic discoveries and the groundbreaking nature of these developments, a thorough treatment of the methods in the area seems timely and appropriate and is the goal of Epigenetics Protocols. The scope of epigenetics is vast, and an exhaustive analysis of all of the techniques employed by investigators would be unrealistic. However, this TM volume of Methods in Molecular Biology covers three main areas that should be of greatest interest to epigenetics investigators: (1) techniques related to analysis of chromatin remodeling, such as histone acetylation and methylation; (2) methods in newly developed and especially promising areas of epigenetics such as telomere position effects, quantitative epigenetics, and ADP ribosylation; and (3) an updated analysis of techniques involving DNA methylation and its role in the modification, as well as the maintenance, of chromatin structure.

Radionanomedicine

Author : Dong Soo Lee
Publisher : Springer
ISBN 13 : 9783319677194
Total Pages : 0 pages
Book Rating : 4.6/5 (771 download)

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Book Synopsis Radionanomedicine by : Dong Soo Lee

Download or read book Radionanomedicine written by Dong Soo Lee and published by Springer. This book was released on 2018-06-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes radionanomedicine as an integrated medicine using exogenous and endogenous This book describes radionanomedicine as an integrated approach that uses exogenous and endogenous nanomaterials for in vivo and human applications. It comprehensively explains radionanomedicine comprising nuclear and nanomedicine, demonstrating that it is more than radionanodrugs and that radionanomedicine also takes advantage of nuclear medicine using trace technology, in which miniscule amounts of materials and tracer kinetic elucidate in vivo biodistribution. It also discusses exogenous nanomaterials such as inorganic silica, iron oxide, upconversion nanoparticles and quantum dots or organic liposomes labelled with radioisotopes, and radionanomaterials used for targeted delivery and imaging for theranostic purposes. Further, it examines endogenous nanomaterials i.e. extracellular vesicles labelled with radioisotopes, known as radiolabelled extracellular vesicles, as well as positron emission tomography (PET) and single photon emission computed tomography (SPECT), which elucidate the biodistribution and potential for therapeutic success.

Biomedical Applications of Functionalized Nanomaterials

Author : Bruno Filipe Carmelino Cardoso Sarmento
Publisher : Elsevier
ISBN 13 : 9780323508780
Total Pages : 0 pages
Book Rating : 4.5/5 (87 download)

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Book Synopsis Biomedical Applications of Functionalized Nanomaterials by : Bruno Filipe Carmelino Cardoso Sarmento

Download or read book Biomedical Applications of Functionalized Nanomaterials written by Bruno Filipe Carmelino Cardoso Sarmento and published by Elsevier. This book was released on 2018-03-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies.