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Immunotherapy In Renal Cell Carcinoma
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Book Synopsis Immunotherapy of Renal Cell Carcinoma by : Frans M.J. Debruyne
Download or read book Immunotherapy of Renal Cell Carcinoma written by Frans M.J. Debruyne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Book Synopsis Immunotherapy in Renal Cell Carcinoma by : Walter J. Storkus
Download or read book Immunotherapy in Renal Cell Carcinoma written by Walter J. Storkus and published by Frontiers Media SA. This book was released on 2023-08-07 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kidney Cancer written by Primo N. Lara and published by Springer. This book was released on 2015-06-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
Book Synopsis Nephron-Sparing Surgery by : Krishna Sasidharan
Download or read book Nephron-Sparing Surgery written by Krishna Sasidharan and published by CRC Press. This book was released on 2007-10-18 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the rising popularity of the minimally invasive laparoscopic option, open nephron-sparing surgery is still seen by many experts as the 'gold standard' for open surgery for kidney tumors and should remain the first choice for many patients. This challenges the idea that less-invasive therapies are always more desirable than open surgery. Whi
Book Synopsis Cancer Immunotherapy Principles and Practice by : Lisa H. Butterfield
Download or read book Cancer Immunotherapy Principles and Practice written by Lisa H. Butterfield and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part 1: Intratumoral Signatures Associated With Immune Responsiveness
Book Synopsis Immunotherapy of Renal Cell Carcinoma by : R. J. a Van Moorselaar
Download or read book Immunotherapy of Renal Cell Carcinoma written by R. J. a Van Moorselaar and published by . This book was released on 1991-01-29 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Contemporary Research on Renal Cell Carcinoma by : Gerd Staehler
Download or read book Contemporary Research on Renal Cell Carcinoma written by Gerd Staehler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of advanced renal cell carcinoma is still problematic. Surgery, although the therapy of choice for locally advanced renal tumors, is still controversial as the treatment for metastases. The role of surgery in the management of patients with pulmonary, bony, and liver metastasis is one of the subject matters discussed in this book. Our results with series of patients undergoing resection of metastases from the lung, bone, and liver show that surgery may be appropriate in selected patients with a good performance status, although most of them certainly cannot be cured by this procedure alone, i.e., in the absence of effective adjuvant therapies. As recent developments show, new strategies for immunotherapy of renal cell carcinoma represent a modest advance over traditional approaches in the treatment of this cancer, such as chemo- and radiotherapy. Clinical trials employing recombinant interferon-a and interleukin 2 produced response rates in up to 30% of patients treated, as evidenced by the European Immunotherapy Trials Program. The adverse reactions and the lack of efficacy in the majority of patients warrants the search for new immunotherapeutic approaches.
Book Synopsis Renal Cell Carcinoma by : Eric A. Klein
Download or read book Renal Cell Carcinoma written by Eric A. Klein and published by CRC Press. This book was released on 1993-04-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.
Download or read book Immunotherapy written by Aung Naing and published by Springer Nature. This book was released on 2022-01-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist. Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events. As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions. The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy. Chapters will discuss topics such as biomarkers of response, resistance mechanisms, role of imaging in predicting immune-related adverse events, and management of immune-related adverse events. Written by leading experts conducting cutting-edge research, readers will gain up-to-date knowledge on the current state and future of immunotherapy.
Book Synopsis Integrating Multidisciplinary Treatment for Advanced Renal Cell Carcinoma by : Rana R. McKay
Download or read book Integrating Multidisciplinary Treatment for Advanced Renal Cell Carcinoma written by Rana R. McKay and published by Springer Nature. This book was released on 2023-12-03 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of kidney cancer has dramatically evolved over the past several years due to notable advances. Most importantly, systemic treatment options have expanded to include combination regimens for advanced disease and expansion of treatment options in the adjuvant setting. Additionally, surgical management has evolved towards nephron-sparing and minimally invasive approaches for treatment of localized disease; the role of surgery and focal therapy are changing for patients with advanced disease. While kidney cancer is a common malignancy in both men and women worldwide, mortality has improved over time given advancements in modern oncology. This book provides a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The book reviews new data about systemic treatment options for patients with advanced disease including strategies in the treatment naïve and post frontline setting. It covers new data regarding perioperative and adjuvant treatments for patients with localized disease and will highlight novel targets and treatments under development. Integration of surgery and systemic therapy through cytoreductive and consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain will also be discussed. Additionally, the book discusses the evolving role of alternative focal approaches including radiation therapy for patients with advanced disease. This text serves as a very useful resource for physicians and researchers dealing with and interested in this challenging malignancy. Specifically, urologists, medical oncologists, radiation oncologists, basic science and translational researchers with interest in RCC, fellows in urologic oncology, upper level residents training in urology and medical oncology, and pharmaceutical partners interested in RCC will benefit most significantly. Integrating Multidisciplinary Treatment for Advanced Renal Cell Carcinoma will provide a concise yet comprehensive summary of strategies for sequencing therapies that will help guide patient care and stimulate investigative efforts.
Book Synopsis Basic and Clinical Research on Renal Cell Carcinoma by : Gerd Staehler
Download or read book Basic and Clinical Research on Renal Cell Carcinoma written by Gerd Staehler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Renal Cell Carcinoma (RCC) cannot be cured by surgery alone. Its resillience to irradiation and chemotherapy demands a new approach to the management of this disease. This book provides an overview of the scientific and clinical developments of RCC, and clarifies the fields ofimmunotherapy and immunobiology. The book contains a compilation of approaches that will enhance the effectiveness of the management of advancedRCC, even in the absence of definitive pre-clinical data. These require additional study and will stimulate the reassessment of preliminary results.Furthermore, preliminary results of already implemented clinical trials withbiological modifiers are presented. Of special interest are the current achievements in the field of immunotherapy using topically and subcutaneously low dosage combinations of cytokines. This concise volume will benefit those seeking a thorough review of the research and the clinical aspects of RCC simultaneously.
Book Synopsis Renal Cell Carcinoma by : Ronald M. Bukowski
Download or read book Renal Cell Carcinoma written by Ronald M. Bukowski and published by Springer Science & Business Media. This book was released on 2000-04-10 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal cell carcinoma represents a heterogeneous group of tumors, the most common of which is clear cell adenocarcinoma. The annual incidence of this tumor appears to be rising and approximately 12,000 individuals die from this cancer annually in the United States. One third of patients who present have metastatic disease at the time of diagnosis, and another 40% who undergo nephrectomy will ultimately develop this complication. Over the past 10 years, a significant amount of new information concerning the epidemiology, mole- lar and immunologic characteristics, and therapy for patients with these tumors has appeared. The recognition that inherited forms of renal cancer exist, and that chromosomal abn- malities can be identified in these tumors, suggested a genetic basis for renal cell carcinoma. The familial cancer syndrome, Von Hippel Lindau disease, provided the setting in which the genetic abnormalites associated with the development of renal cancer were first described. Abnormalities of the VHL gene have also been detected in sporadic clear cell carcinoma, and it has now been recognized that approximately 80 % of these tumors will demonstrate ch- acteristic alterations. Currently the functions of the VHL protein are being investigated, and the biology of clear cell carcinoma of the kidney is under study. Additionally, papillary carcinomas of the kidney appear to express different molecular defects, and these are now being unraveled.
Book Synopsis Chemotherapy and Immunotherapy in Urologic Oncology by : Edouard J. Trabulsi
Download or read book Chemotherapy and Immunotherapy in Urologic Oncology written by Edouard J. Trabulsi and published by Springer Nature. This book was released on 2020-09-29 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.
Book Synopsis Renal Cell Carcinoma by : Ronald M. Bukowski
Download or read book Renal Cell Carcinoma written by Ronald M. Bukowski and published by Springer. This book was released on 2014-11-27 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this critically acclaimed book has updated and expanded the survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. Internationally renowned editors and contributors explore the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Third Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by leaders of the field.
Book Synopsis WHO Classification of Tumours of the Urinary System and Male Genital Organs by : International Agency for Research on Cancer
Download or read book WHO Classification of Tumours of the Urinary System and Male Genital Organs written by International Agency for Research on Cancer and published by . This book was released on 2016-02-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Urinary System and Male Genital Organs is the eighth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. It contains numerous color photographs, MRIs, ultrasound images, CT scans, charts and references.
Book Synopsis Diseases of the Abdomen and Pelvis 2018-2021 by : Juerg Hodler
Download or read book Diseases of the Abdomen and Pelvis 2018-2021 written by Juerg Hodler and published by Springer. This book was released on 2018-03-20 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.
Book Synopsis Contemporary Research on Renal Cell Carcinoma by : Gerd Staehler
Download or read book Contemporary Research on Renal Cell Carcinoma written by Gerd Staehler and published by Springer. This book was released on 1994-03-18 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of advanced renal cell carcinoma is still problematic. Surgery, although the therapy of choice for locally advanced renal tumors, is still controversial as the treatment for metastases. The role of surgery in the management of patients with pulmonary, bony, and liver metastasis is one of the subject matters discussed in this book. Our results with series of patients undergoing resection of metastases from the lung, bone, and liver show that surgery may be appropriate in selected patients with a good performance status, although most of them certainly cannot be cured by this procedure alone, i.e., in the absence of effective adjuvant therapies. As recent developments show, new strategies for immunotherapy of renal cell carcinoma represent a modest advance over traditional approaches in the treatment of this cancer, such as chemo- and radiotherapy. Clinical trials employing recombinant interferon-a and interleukin 2 produced response rates in up to 30% of patients treated, as evidenced by the European Immunotherapy Trials Program. The adverse reactions and the lack of efficacy in the majority of patients warrants the search for new immunotherapeutic approaches.
