Immunology of Clinical and Experimental Diabetes

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Publisher : Springer Science & Business Media
ISBN 13 : 1468445596
Total Pages : 432 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunology of Clinical and Experimental Diabetes by : Sudhir Gupta

Download or read book Immunology of Clinical and Experimental Diabetes written by Sudhir Gupta and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past 5 years, impressive progress has been made in understanding the etiopathogenesis of expeiimental and clinical diabetes. The rapid progress that has been made in the general field of immunology has made possible new understanding regarding the role of the immune system in the pathogenesis of diabetes. The other two areas in which recent progress has been made in the field of diabetes include genetics and the role of infectious agent(s) in the etiopathogenesis of diabetes. Because of these recent developments, a vast amount of data has been accumulated and published in a number of metabolic, endocrine, immunological, and general medicine journals. The purpose of this book is to consolidate all the available information and present it in its current state. In the present volume, I strive to bring together relevant contributions from leaders in the fields of immunopathology, immunobiology, and genetics. The advancing understanding has in several instances reached the point of clinical applica tion. This volume encompasses the entire scope of modem immunology of diabetes mellitus. This volume has been divided into two major parts, Experimental Diabetes and Clinical Diabetes. In the Experimental part are included chapters dealing with the structure and functions of insulin and the immune response to insulin. Spontaneous and experimentally induced models of type I diabetes mellitus are presented. The role of virus(es) in the etiology of experimental diabetes and the influence of sex on experi mental diabetes are discussed. The transplantation of pancreas and islets is reviewed in detail.

Immunology of Clinical and Experimental Diabetes

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Publisher :
ISBN 13 : 9781468445602
Total Pages : 452 pages
Book Rating : 4.4/5 (456 download)

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Book Synopsis Immunology of Clinical and Experimental Diabetes by : Sudhir Gupta

Download or read book Immunology of Clinical and Experimental Diabetes written by Sudhir Gupta and published by . This book was released on 2014-01-15 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunopathology of Insulin

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Publisher : Elsevier
ISBN 13 : 1483162184
Total Pages : 201 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Immunopathology of Insulin by : K. Federlin

Download or read book Immunopathology of Insulin written by K. Federlin and published by Elsevier. This book was released on 2014-05-20 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monographs on Endocrinology, Volume 6: Immunopathology of Insulin provides information pertinent to the fundamental aspects of immunopathology of insulin. This book covers a variety of topics, including cell mediated immunity, biological effects of insulin, insulin allergy, insulin immunology, and humoral insulin antibodies. Organized into six chapters, this volume begins with an overview of the causal relationship between delayed hypersensitivity and antibody production. This text then explains the molecular localization of the most important immunologic components of the insulin molecule. Other chapters consider the clinical observation of allergic reactions of insulin antibodies in the tissue and the in vitro method of standard serology. This book discusses as well methods used for demonstration of insulin antibodies in humans and experimental animals. The final chapter deals with the investigations concerned with the various kinds of immune reactions, which follow the injection of insulin. This book is a valuable resource for endocrinologists, immunologists, and diabetologists.

Type 1 Diabetes

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306478710
Total Pages : 364 pages
Book Rating : 4.4/5 (787 download)

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Book Synopsis Type 1 Diabetes by : George S. Eisenbarth

Download or read book Type 1 Diabetes written by George S. Eisenbarth and published by Springer Science & Business Media. This book was released on 2004-11-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the field of immunology, type 1 diabetes has become one of the major areas of investigation with studies that span from characterization of key molecules to trials for the prevention of the disease. Type 1 Diabetes : Molecular, Cellular and Clinical Immunology communicates both the background and the most recent understanding of this disorder, which will almost certainly be central to elucidating the etiology of autoimmunity, and in particular of organ specific autoimmunity. The book covers immunogenetics, immunopathogenesis, epidemiology, disease prediction and clinical application of current knowledge. Both scientists seeking to understand and prevent type 1 diabetes/autoimmunity as well as physicians caring for families with type 1 diabetes will be interested in this book.

The Role of Viruses and the Immune System in Diabetes Mellitus

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Publisher : Springer Science & Business Media
ISBN 13 : 364275239X
Total Pages : 148 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Role of Viruses and the Immune System in Diabetes Mellitus by : Thomas Dyrberg

Download or read book The Role of Viruses and the Immune System in Diabetes Mellitus written by Thomas Dyrberg and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in diabetes has accelerated in two areas, both of which are being reviewed in CTMI. The first is the use of a variety of animal models; the second is basic research in human investigation, islet cell antigens, and mapping of genes as sociated with susceptibility to disease. Dr. Thomas Dyrberg accepted editorial responsibility for this volume, which covers the first area. A second book, to be published later in the year, is edited by Drs. Brekkeskov and Hansen (CTMI 164, see page VI for contents). Although the contributors to both volumes represent the international scientific community, the editors are from the Hagedorn Research Laboratory in Denmark. Work at this institute and the Steno Memorial Hospital has been dedicated to research in diabetes for decades, and the insti tutions were appointed WHO Collaborating Centres for Re search and Training on the Pathogenesis of Diabetes Mellitus in 1983. It is worth noting that while addressing the hypothesis of the role of class II major histocompatibility glycoproteins in autoimmune diabetes (insulin-dependent diabetes, IDDM) a number of investigators established animal models in which class II molecules were expressed under the control of the rat insulin promoter. While generating interesting information on 100M, the finding of immunologic tolerance in such transgenic mice has attracted the attention of several basic immunologic laboratories for quite different reasons. Thus, we are reminded again of the Pasteur dictum that "chance favors the prepared mind. " Michael B. A. Oldstone, M. D.

Immunopathology of Insulin

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Publisher :
ISBN 13 : 9783642806094
Total Pages : 208 pages
Book Rating : 4.8/5 (6 download)

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Book Synopsis Immunopathology of Insulin by : Konrad Federlin

Download or read book Immunopathology of Insulin written by Konrad Federlin and published by . This book was released on 1971-01-01 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The BALB/c Mouse

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Publisher : Springer Science & Business Media
ISBN 13 : 3642707408
Total Pages : 261 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The BALB/c Mouse by : Michael Potter

Download or read book The BALB/c Mouse written by Michael Potter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse was first used in immunological research by Paul Ehrlich in 1891 in an extraordinary series of experiments on the maternal transfer of antitoxic immunity. A short 22 years later in 1913 Halsey Bagg acquired a stock of albino mice from a commercial dealer and used them in a series of experiments on learning. Because he was interested in the genetics of intelligence, Halsey Bagg began breeding a pedigreed line of these mice that were subsequently named for him - Bagg Albino. Though Halsey Bagg is not credited with initiating the inbred strains of mice, his stock curiously has played an indisputably important role. Bagg Albinos were progenitors of the present day BALB/c family of sublines - the subject of this book. They were also used as one of the parents in the development of inbred strains A, CBA and C3H, three other very famous strains. Today the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research. The hallmark of the BALB/c response to so many kinds of infections is susceptibility and sometimes an exaggerated susceptibility, but this paradoxically is not associated with immunodeficiency as BALB/c is an excellent responder to immuni zation. These characteristics have made the BALB/c mouse a model for identifying genes that determine susceptibility to infectious and neoplastic diseases. In 1985 the laboratory BALB/c mouse became 72 years old. The current filial generations are somewhere around 350 generations [MURPHY].

Immunotherapy of Type 1 Diabetes

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Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunotherapy of Type 1 Diabetes by : Domenico Andreani

Download or read book Immunotherapy of Type 1 Diabetes written by Domenico Andreani and published by John Wiley & Sons. This book was released on 1989 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1968 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1968 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Type 1 Diabetes

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Publisher : BoD – Books on Demand
ISBN 13 : 9533073624
Total Pages : 674 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Type 1 Diabetes by : David Wagner

Download or read book Type 1 Diabetes written by David Wagner and published by BoD – Books on Demand. This book was released on 2011-11-25 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of reviews about the pathogenesis of Type 1 Diabetes. T1D is a classic autoimmune disease. Genetic factors are clearly determinant but cannot explain the rapid, even overwhelming expanse of this disease. Understanding etiology and pathogenesis of this disease is essential. A number of experts in the field have covered a range of topics for consideration that are applicable to researcher and clinician alike. This book provides apt descriptions of cutting edge technologies and applications in the ever going search for treatments and cure for diabetes. Areas including T cell development, innate immune responses, imaging of pancreata, potential viral initiators, etc. are considered.

Diabetes mellitus

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Publisher : Springer-Verlag
ISBN 13 : 3642746101
Total Pages : 294 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Diabetes mellitus by : Reinhard G. Bretzel

Download or read book Diabetes mellitus written by Reinhard G. Bretzel and published by Springer-Verlag. This book was released on 2013-03-08 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die BeitrAge dieses Buches beschAftigen sich mit AutoimmunitAt, Immuntherapie des Typ-I Diabetes, Virusgenese, Insulintherapie und -allergie. Schwerpunkte liegen auf den dynamischen Aspekten der Insulinsubstitution unter BerA1/4cksichtigung einer angepaAten DiAt und der Therapie mit oralen Antibiotika, Insulinen und Pro-Insulinen. Gleichzeitig wird anhand der Makro-Angiopathie und der Neuropathie auf die Auswirkungen der dynamischen Insulinsubstitution bei SekundArkomplikationen hingewiesen. Die MAglichkeit der computerunterstA1/4tzten TherapiefA1/4hrung und glukosesensorgesteuerten Biofeedback-Kontrolle werden vorgestellt. Ein umfangreiches Kapitel vermittelt den aktuellen Stand der experimentellen Forschung und der klinischen Anwendung der Pankreas- und Inselzelltransplantation.

International Textbook of Diabetes Mellitus

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Publisher : John Wiley & Sons
ISBN 13 : 1118387686
Total Pages : 1240 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis International Textbook of Diabetes Mellitus by : R. A. DeFronzo

Download or read book International Textbook of Diabetes Mellitus written by R. A. DeFronzo and published by John Wiley & Sons. This book was released on 2015-03-05 with total page 1240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.

Perspectives on Autoimmunity

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Publisher : CRC Press
ISBN 13 : 1000083543
Total Pages : 315 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Perspectives on Autoimmunity by : Irun R. Cohen

Download or read book Perspectives on Autoimmunity written by Irun R. Cohen and published by CRC Press. This book was released on 2020-04-15 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, this book offers a full, comprehensive guide to autoimmunity. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine, and other practitioners in their respective fields.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1044 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Clinical Immunology

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Publisher : John Wiley & Sons
ISBN 13 : 1118487877
Total Pages : 661 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Essentials of Clinical Immunology by : Helen Chapel

Download or read book Essentials of Clinical Immunology written by Helen Chapel and published by John Wiley & Sons. This book was released on 2013-12-17 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Clinical Immunology provides the most up-to-date, core information required to understand diseases with an immunological basis. Clinically focussed, the sixth edition of this classic text presents theoretical and practical information in a simple yet thorough way. Essentials of Clinical Immunology covers the underlying pathophysiology, the signs and symptoms of disease, the investigations required and guidance on the management of patients. Perfect for clinical medical students, junior doctors and medical professionals seeking a refresher in the role of immunology in clinical medicine, this comprehensive text features fully updated clinical information, boxes with key points, real-life case histories to illustrate key concepts and an index of contents at the start of each chapter. A companion website at www.immunologyclinic.com provides additional learning tools, including more case studies, interactive multiple-choice questions and answers, all of the photographs and illustrations from the book, links to useful websites, and a selection of review articles from the journal Clinical and Experimental Immunology. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

Stress Challenges and Immunity in Space

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Publisher : Springer Nature
ISBN 13 : 3030169960
Total Pages : 756 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Stress Challenges and Immunity in Space by : Alexander Choukèr

Download or read book Stress Challenges and Immunity in Space written by Alexander Choukèr and published by Springer Nature. This book was released on 2019-11-27 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Clinical Diabetes Mellitus

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Publisher :
ISBN 13 :
Total Pages : 1008 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Clinical Diabetes Mellitus by : John K. Davidson

Download or read book Clinical Diabetes Mellitus written by John K. Davidson and published by . This book was released on 2000 with total page 1008 pages. Available in PDF, EPUB and Kindle. Book excerpt: