Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Immunologic Mechanisms And Predictors Of Susceptibility To Mycobacterium Tuberculosis
Download Immunologic Mechanisms And Predictors Of Susceptibility To Mycobacterium Tuberculosis full books in PDF, epub, and Kindle. Read online Immunologic Mechanisms And Predictors Of Susceptibility To Mycobacterium Tuberculosis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Immunologic Mechanisms and Predictors of Susceptibility to Mycobacterium Tuberculosis by : Gillian Lee Beamer
Download or read book Immunologic Mechanisms and Predictors of Susceptibility to Mycobacterium Tuberculosis written by Gillian Lee Beamer and published by . This book was released on 2009 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to low IFN-[gamma] and low CCL5, elevated levels of IL-10 in the lungs predicted reactivation TB approximately 4-8 weeks prior to disease onset in M.tb susceptible mice. Furthermore, IL-10 was shown to be a single cause of reactivation TB, as disease progression was delayed and protective immunity was enhanced by IL-10 blockade in vivo. Overall, these results indicate that single immune mediators may be used as biomarkers of TB disease progression in humans, and furthermore, that appropriately timed immunotherapeutic intervention may prevent the transition from controlled M.tb infection to active TB disease.
Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes
Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Book Synopsis Immune Correlates of Resistance and Susceptibility to Tuberculosis by : Joshua Charles Cyktor
Download or read book Immune Correlates of Resistance and Susceptibility to Tuberculosis written by Joshua Charles Cyktor and published by . This book was released on 2012 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Tuberculosis (TB) has been a prevalent cause of morbidity and mortality in human beings for centuries, and is still a global health emergency today. Although not the headline of news in the United States, TB is rampant is sub-Saharan Africa and southeast Asia, where it is the number one killer of patients with acquired immunodeficiency syndrome (AIDS). Of the estimated 2 billion people infected with Mycobacterium tuberculosis (Mtb), the etiological agent responsible for TB, only a small percentage progress to active, contagious disease. This is because the immune system of most infected individuals is capable of effectively containing the infection, whereas in a percentage of individuals this containment will eventually fail, leading to reactivation of TB. Reactivation can arise due to numerous factors, including HIV infection, malnutrition, aging, or other immunosuppression. In some individuals, however, reactivation can occur without any overt immune deficiency. In this work, we sought to gain further understanding of the immunological mechanisms behind TB reactivation in susceptible individuals with otherwise intact immune systems.
Download or read book Buruli Ulcer written by Gerd Pluschke and published by Springer. This book was released on 2019-04-29 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
Book Synopsis Tuberculosis Host-Pathogen Interactions by : Jeffrey D. Cirillo
Download or read book Tuberculosis Host-Pathogen Interactions written by Jeffrey D. Cirillo and published by Springer Nature. This book was released on 2019-09-10 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery. Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections. Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions. Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide.
Book Synopsis Tuberculosis in Adults and Children by : Dorothee Heemskerk
Download or read book Tuberculosis in Adults and Children written by Dorothee Heemskerk and published by Springer. This book was released on 2015-07-17 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Book Synopsis Global Tuberculosis Report 2013 by : World Health Organization
Download or read book Global Tuberculosis Report 2013 written by World Health Organization and published by World Health Organization. This book was released on 2013 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the eighteenth global report on tuberculosis (TB) published by WHO in a series that started in 1997. It provides a comprehensive and up-to-date assessment of the TB epidemic and progress in implementing and financing TB prevention care and control at global regional and country levels using data reported by almost 200 countries that account for over 99% of the world's TB cases. Two years before the 2015 deadline for achievement of global TB targets the 2013 report includes a special supplement that assesses progress towards the 2015 targets and the actions needed to accelerate towards or move beyond them.The report has 8 main chapters. The introductory chapter provides general background on TB as well as an explanation of global targets for TB control the WHO's Stop TB Strategy that covers the period 2006-2015 and the development of a post-2015 global TB strategy. The remaining seven chapters cover the disease burden caused by TB (incidence prevalence mortality); TB case notifications and treatment outcomes; drug resistance surveillance among TB patients and the programmatic response in detecting and providing treatment for multidrug-resistant TB; diagnostics and laboratory strengthening for TB; addressing the co-epidemics of TB and HIV; financing TB care and control; and research and development for new TB diagnostics drugs and vaccines.The four annexes of the report include a thorough explanation of methods used to estimate the burden of disease caused by TB one-page profiles for 22 high TB-burden countries and tables of data on key indicators for all countries organized by WHO region.
Book Synopsis Tuberculosis in the Workplace by : Institute of Medicine
Download or read book Tuberculosis in the Workplace written by Institute of Medicine and published by National Academies Press. This book was released on 2001-05-15 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Before effective treatments were introduced in the 1950s, tuberculosis was a leading cause of death and disability in the United States. Health care workers were at particular risk. Although the occupational risk of tuberculosis has been declining in recent years, this new book from the Institute of Medicine concludes that vigilance in tuberculosis control is still needed in workplaces and communities. Tuberculosis in the Workplace reviews evidence about the effectiveness of control measuresâ€"such as those recommended by the Centers for Disease Control and Preventionâ€"intended to prevent transmission of tuberculosis in health care and other workplaces. It discusses whether proposed regulations from the Occupational Safety and Health Administration would likely increase or sustain compliance with effective control measures and would allow adequate flexibility to adapt measures to the degree of risk facing workers.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Understanding Tuberculosis by : Pere-Joan Cardona
Download or read book Understanding Tuberculosis written by Pere-Joan Cardona and published by BoD – Books on Demand. This book was released on 2012-02-24 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycobacterium tuberculosis in an attempt to understand the extent to which the bacilli has adapted itself to the host and to its final target. On the other hand, there is a section in which other specialists discuss how to manipulate this immune response to obtain innovative prophylactic and therapeutic approaches to truncate the intimal co-evolution between Mycobacterium tuberculosis and the Homo sapiens.
Book Synopsis Collaborative Framework for Care and Control of Tuberculosis and Diabetes by : World Health Organization
Download or read book Collaborative Framework for Care and Control of Tuberculosis and Diabetes written by World Health Organization and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Given the absence of international guidelines on the joint management and control of TB and diabetes, the World Health Organization (WHO) and the International Union Against Tuberculosis and Lung Disease (the Union) identified key questions to be answered and commissioned systematic reviews of studies addressing those questions. A series of expert consultations were organized to assess the findings of the systematic reviews and a guideline group was established to develop this provisional collaborative framework. The framework aims to guide national programmes, clinicians and others engaged in care of patients and prevention and control of diabetes and TB on how to establish a coordinated response to both diseases, at organizational and clinical levels. The framework is based on evidence collated from systematic reviews and existing guidelines on the diagnosis and management of TB and diabetes. The systematic reviews confirmed the weak evidence base for the effectiveness and cost-effectiveness of collaborative interventions. The framework is therefore provisional; several of its recommendations are provisional pending better evidence. In order to provide advice on how to fill the knowledge gaps, the framework includes a list of priority research areas."--Page vii-viii.
Book Synopsis Tuberculosis of the Central Nervous System by : Mehmet Turgut
Download or read book Tuberculosis of the Central Nervous System written by Mehmet Turgut and published by Springer. This book was released on 2017-06-13 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by leading international authorities in the field, this book provides an in-depth review of knowledge of tuberculosis of the central nervous system, with emphasis on clinical, diagnostics, and therapeutic features. Tuberculosis, one of the most lethal diseases in human history, still poses a serious threat in the world together with economic and social problems, although a great progress in the fight against this infectious disease in the last century. It covers the full range of tuberculosis of central nervous system and the chapters are organized into six sections: (1) the cranial; (2) the spinal; and (3) the peripheral portions of the nervous system; followed by (4) a section on the laboratory studies in tuberculosis; (5) a section on medical and surgical therapy; and (6) further insights into tuberculosis. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and specialists upon infectious diseases seeking both basic and more sophisticated information and surgical procedures relating to the complications associated with tuberculosis involving the spine, brain and peripheral nerves.
Book Synopsis Disease Control Priorities in Developing Countries by : Dean T. Jamison
Download or read book Disease Control Priorities in Developing Countries written by Dean T. Jamison and published by World Bank Publications. This book was released on 2006-04-02 with total page 1449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
Book Synopsis Stress Challenges and Immunity in Space by : Alexander Choukèr
Download or read book Stress Challenges and Immunity in Space written by Alexander Choukèr and published by Springer Nature. This book was released on 2019-11-27 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Global Tuberculosis Report 2019 by : World Health Organization
Download or read book Global Tuberculosis Report 2019 written by World Health Organization and published by . This book was released on 2019-08-12 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO has published a global TB report every year since 1997. The main aim of the report is to provide a comprehensive and up-to-date assessment of the TB epidemic, and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of recommended global TB strategies and targets endorsed by WHO?s Member States, broader development goals set by the United Nations (UN) and targets set in the political declaration at the first UN high-level meeting on TB (held in September 2018). The 2019 edition of the global TB report was released on 17 October 2019. The data in this report are updated annually. Please note that direct comparisons between estimates of TB disease burden in the latest report and previous reports are not appropriate. The most recent time-series of estimates are published in the 2019 global TB report.
Book Synopsis A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis by : Franz Joel Leong
Download or read book A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis written by Franz Joel Leong and published by CRC Press. This book was released on 2016-04-19 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis
Book Synopsis Biomedical Translational Research by : R.C. Sobti
Download or read book Biomedical Translational Research written by R.C. Sobti and published by Springer Nature. This book was released on 2022-06-14 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.
