Immunologic Defects In Laboratory Animals 1

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Immunologic Defects in Laboratory Animals 1

Author : M. Eric Gershwin
Publisher : Springer Science & Business Media
ISBN 13 : 1475703252
Total Pages : 365 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Immunologic Defects in Laboratory Animals 1 by : M. Eric Gershwin

Download or read book Immunologic Defects in Laboratory Animals 1 written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.

Immunologic defects in laboratory animals

Author : M. Eric Gershwin
Publisher :
ISBN 13 :
Total Pages : 26 pages
Book Rating : 4.:/5 (834 download)

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Book Synopsis Immunologic defects in laboratory animals by : M. Eric Gershwin

Download or read book Immunologic defects in laboratory animals written by M. Eric Gershwin and published by . This book was released on 1981 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunologic Defects in Laboratory Animals 2

Author : M. Eric Gershwin
Publisher : Springer
ISBN 13 : 9781468486520
Total Pages : 0 pages
Book Rating : 4.4/5 (865 download)

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Book Synopsis Immunologic Defects in Laboratory Animals 2 by : M. Eric Gershwin

Download or read book Immunologic Defects in Laboratory Animals 2 written by M. Eric Gershwin and published by Springer. This book was released on 2013-05-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.

Immunologic Defects in Laboratory Animals 2

Author : M. Eric Gershwin
Publisher : Springer
ISBN 13 : 9781468486544
Total Pages : 0 pages
Book Rating : 4.4/5 (865 download)

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Book Synopsis Immunologic Defects in Laboratory Animals 2 by : M. Eric Gershwin

Download or read book Immunologic Defects in Laboratory Animals 2 written by M. Eric Gershwin and published by Springer. This book was released on 2012-11-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.

Immunologic Defects in Laboratory Animals

Author : 3Island Press
Publisher :
ISBN 13 : 9781475703269
Total Pages : 384 pages
Book Rating : 4.7/5 (32 download)

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Book Synopsis Immunologic Defects in Laboratory Animals by : 3Island Press

Download or read book Immunologic Defects in Laboratory Animals written by 3Island Press and published by . This book was released on 1981-09-30 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Use of Laboratory Animals in Biomedical and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council

Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Laboratory Animal Medicine

Author : James G. Fox
Publisher : Academic Press
ISBN 13 : 1483269167
Total Pages : 769 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Laboratory Animal Medicine by : James G. Fox

Download or read book Laboratory Animal Medicine written by James G. Fox and published by Academic Press. This book was released on 2013-10-02 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Immunological Disorders in Mice

Author : Blanka Rihova
Publisher : CRC Press
ISBN 13 : 9780849356353
Total Pages : 288 pages
Book Rating : 4.3/5 (563 download)

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Book Synopsis Immunological Disorders in Mice by : Blanka Rihova

Download or read book Immunological Disorders in Mice written by Blanka Rihova and published by CRC Press. This book was released on 1990-11-21 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Disorders in Mice focuses on immunological reactions and diseases based on models provided through studies on genetically based immunological disorders in inbred strains of mice. The book discusses various defects affecting all levels of immunological response, featuring new data on "classical" mutations, as well as information regarding lesser known immune defects. New areas presented include genetic manipulation, ontogenetic aspects, clinical implications, the effect of drugs on immunodefective strains, and neuroendocrine regulation. A critical evaluation of the data presented through these studies on immune disorders in mice will facilitate the understanding of immunological processes and have significant application in clinical practice. Theoretical immunologists, animal breeding companies, and clinical immunologists will find this text invaluable.

Immunodeficient Rodents

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309092876
Total Pages : 257 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Immunodeficient Rodents by : National Research Council

Download or read book Immunodeficient Rodents written by National Research Council and published by National Academies Press. This book was released on 1989-02-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.

Cellular Immunology LabFax

Author :
Publisher : Elsevier
ISBN 13 : 1483297705
Total Pages : 280 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Cellular Immunology LabFax by :

Download or read book Cellular Immunology LabFax written by and published by Elsevier. This book was released on 2014-05-19 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: LABFAX volumes are purpose-designed data reference books for practicing scientists. Each book presents the key information for a major subject in one place and so saves hours of searching. The authors and editors of each LABFAX volume have searched the original literature for the accurate data they know the subject specialist needs. Cellular Immunology Labfax is a detailed compendium of information on the tissues and cells of the immune system, cell lines and hybridomas, antigens and receptors, the major histocompatibility complex, soluble immunoregulatory molecules, in vivo procedures, important features of species used in immunological research, and much more. The contents of Cellular Immunology Labfax have been carefully chosen to complement the data presented in Immunochemistry Labfax. It is therefore the companion volume to this text.

ILAR News

Author :
Publisher :
ISBN 13 :
Total Pages : 566 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis ILAR News by :

Download or read book ILAR News written by and published by . This book was released on 1980 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guide for the Care and Use of Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Guide for the Care and Use of Laboratory Animals

Author :
Publisher : National Academies
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.1/5 (317 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by :

Download or read book Guide for the Care and Use of Laboratory Animals written by and published by National Academies. This book was released on 1985 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Control of the Susceptibility to Bacterial Infection

Author : David E. Briles
Publisher : Springer Science & Business Media
ISBN 13 : 3642709869
Total Pages : 181 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Genetic Control of the Susceptibility to Bacterial Infection by : David E. Briles

Download or read book Genetic Control of the Susceptibility to Bacterial Infection written by David E. Briles and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guide for the Care and Use of Laboratory Animals -- Japanese Edition

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309100186
Total Pages : 142 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals -- Japanese Edition by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals -- Japanese Edition written by National Research Council and published by National Academies Press. This book was released on 1997-01-31 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Guide for the Care and Use of Laboratory Animals -- Korean Edition

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309103657
Total Pages : 128 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals -- Korean Edition by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals -- Korean Edition written by National Research Council and published by National Academies Press. This book was released on 2005-08-27 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.